|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 354 for Col4a3

<< First    < Previous  |  Next >    Last >>
0.05s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: chicken
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression
Probe: MGI:7336864
Assay Type: RNA in situ
Annotation Date: 2023-08-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3268226
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7520042
Age: embryonic day 18.0
Image: 6I Col4a3 E18
Note: Expression somewhat specific to alveolar type I (AT1) epithelial cells.
Specimen Label: 6I Col4a3 E18
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:7336864
Assay Type: RNA in situ
Annotation Date: 2023-08-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3268227
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7520042
Age: postnatal day 0
Image: 6I Col4a3 P0
Note: Expression somewhat specific to alveolar type I (AT1) epithelial cells.
Specimen Label: 6I Col4a3 P0
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:7336864
Assay Type: RNA in situ
Annotation Date: 2023-08-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3268226
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7520042
Age: embryonic day 18.0
Image: S10B Col4a3 E18
Note: Expression somewhat specific to alveolar type I (AT1) epithelial cells.
Specimen Label: S10B Col4a3 E18
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:7336864
Assay Type: RNA in situ
Annotation Date: 2023-08-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3268227
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7520042
Age: postnatal day 0
Image: S10B Col4a3 P0
Note: Expression somewhat specific to alveolar type I (AT1) epithelial cells.
Specimen Label: S10B Col4a3 P0
Detected: true
Specimen Num: 5
GXD Expression
Probe: MGI:7336864
Assay Type: RNA in situ
Annotation Date: 2023-08-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3268226
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7520042
Age: embryonic day 18.0
Image: S10D Col4a3 E18
Note: Expression somewhat specific to alveolar type I (AT1) epithelial cells.
Specimen Label: S10D Col4a3 E18
Detected: true
Specimen Num: 7
GXD Expression
Probe: MGI:7336864
Assay Type: RNA in situ
Annotation Date: 2023-08-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3268227
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7520042
Age: postnatal day 0
Image: S10D Col4a3 P0
Note: Expression somewhat specific to alveolar type I (AT1) epithelial cells.
Specimen Label: S10D Col4a3 P0
Detected: true
Specimen Num: 8
GXD Expression
Probe: MGI:7336864
Assay Type: RNA in situ
Annotation Date: 2023-08-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3268228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7520042
Age: postnatal day 5
Image: 6I Col4a3 P5
Note: Expression somewhat specific to alveolar type I (AT1) epithelial cells.
Specimen Label: 6I Col4a3 P5
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:7336864
Assay Type: RNA in situ
Annotation Date: 2023-08-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3268228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7520042
Age: postnatal day 5
Image: S10B Col4a3 P5
Note: Expression somewhat specific to alveolar type I (AT1) epithelial cells.
Specimen Label: S10B Col4a3 P5
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:7336864
Assay Type: RNA in situ
Annotation Date: 2023-08-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3268228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7520042
Age: postnatal day 5
Image: S10D Col4a3 P5
Note: Expression somewhat specific to alveolar type I (AT1) epithelial cells.
Specimen Label: S10D Col4a3 P5
Detected: true
Specimen Num: 9
Publication
First Author: Cosgrove D
Year: 1996
Journal: Genes Dev
Title: Collagen COL4A3 knockout: a mouse model for autosomal Alport syndrome.
Volume: 10
Issue: 23
Pages: 2981-92
Publication
First Author: Lu W
Year: 1999
Journal: Genomics
Title: Insertional mutation of the collagen genes Col4a3 and Col4a4 in a mouse model of Alport syndrome.
Volume: 61
Issue: 2
Pages: 113-24
Publication
First Author: Kim M
Year: 2015
Journal: PLoS One
Title: Progression of Alport Kidney Disease in Col4a3 Knock Out Mice Is Independent of Sex or Macrophage Depletion by Clodronate Treatment.
Volume: 10
Issue: 11
Pages: e0141231
Publication  
First Author: Odiatis C
Year: 2021
Journal: Matrix Biol Plus
Title: A glycine substitution in the collagenous domain of Col4a3 in mice recapitulates late onset Alport syndrome.
Volume: 9
Pages: 100053
Publication  
First Author: Pokidysheva EN
Year: 2021
Journal: J Biol Chem
Title: Collagen IVα345 dysfunction in glomerular basement membrane diseases. I. Discovery of a COL4A3 variant in familial Goodpasture's and Alport diseases.
Volume: 296
Pages: 100590
Publication  
First Author: Rubel D
Year: 2014
Journal: Matrix Biol
Title: Collagen receptors integrin alpha2beta1 and discoidin domain receptor 1 regulate maturation of the glomerular basement membrane and loss of integrin alpha2beta1 delays kidney fibrosis in COL4A3 knockout mice.
Volume: 34
Pages: 13-21
Publication
First Author: Heidet L
Year: 2003
Journal: Am J Pathol
Title: A human-mouse chimera of the alpha3alpha4alpha5(IV) collagen protomer rescues the renal phenotype in Col4a3-/- Alport mice.
Volume: 163
Issue: 4
Pages: 1633-44
Publication  
First Author: LeBleu VS
Year: 2024
Journal: Life Sci Alliance
Title: Genetic reprogramming with stem cells regenerates glomerular epithelial podocytes in Alport syndrome.
Volume: 7
Issue: 6
Publication
First Author: Funk SD
Year: 2019
Journal: Am J Physiol Renal Physiol
Title: Endothelial cell-specific collagen type IV-α3 expression does not rescue Alport syndrome in Col4a3-/- mice.
Volume: 316
Issue: 5
Pages: F830-F837
Publication
First Author: Pieri M
Year: 2014
Journal: J Am Soc Nephrol
Title: Evidence for activation of the unfolded protein response in collagen IV nephropathies.
Volume: 25
Issue: 2
Pages: 260-75
Publication
First Author: Beirowski B
Year: 2006
Journal: J Am Soc Nephrol
Title: Chronic renal failure and shortened lifespan in COL4A3+/- mice: an animal model for thin basement membrane nephropathy.
Volume: 17
Issue: 7
Pages: 1986-94
Publication
First Author: Gross O
Year: 2003
Journal: Kidney Int
Title: Preemptive ramipril therapy delays renal failure and reduces renal fibrosis in COL4A3-knockout mice with Alport syndrome.
Volume: 63
Issue: 2
Pages: 438-46
Publication
First Author: Baxter RM
Year: 2007
Journal: Matrix Biol
Title: The plant pathogenesis related protein GLIPR-2 is highly expressed in fibrotic kidney and promotes epithelial to mesenchymal transition in vitro.
Volume: 26
Issue: 1
Pages: 20-9
Publication
First Author: Dai B
Year: 2012
Journal: Kidney Int
Title: Assessment of 24,25(OH)2D levels does not support FGF23-mediated catabolism of vitamin D metabolites.
Volume: 82
Issue: 10
Pages: 1061-70
Publication
First Author: Bae EH
Year: 2017
Journal: Kidney Int
Title: Murine recombinant angiotensin-converting enzyme 2 attenuates kidney injury in experimental Alport syndrome.
Volume: 91
Issue: 6
Pages: 1347-1361
Publication
First Author: Andrews KL
Year: 2002
Journal: Am J Pathol
Title: Quantitative trait loci influence renal disease progression in a mouse model of Alport syndrome.
Volume: 160
Issue: 2
Pages: 721-30
Publication
First Author: Cosgrove D
Year: 1998
Journal: Hear Res
Title: Ultrastructural, physiological, and molecular defects in the inner ear of a gene-knockout mouse model for autosomal Alport syndrome.
Volume: 121
Issue: 1-2
Pages: 84-98
Publication
First Author: Dufek B
Year: 2020
Journal: PLoS One
Title: RNA-seq analysis of gene expression profiles in isolated stria vascularis from wild-type and Alport mice reveals key pathways underling Alport strial pathogenesis.
Volume: 15
Issue: 8
Pages: e0237907
Publication
First Author: Hamano Y
Year: 2002
Journal: J Biol Chem
Title: Determinants of vascular permeability in the kidney glomerulus.
Volume: 277
Issue: 34
Pages: 31154-62
Publication
First Author: Tsuji K
Year: 2017
Journal: Sci Rep
Title: Ultrastructural Characterization of the Glomerulopathy in Alport Mice by Helium Ion Scanning Microscopy (HIM).
Volume: 7
Issue: 1
Pages: 11696
Publication  
First Author: Murata T
Year: 2016
Journal: Sci Rep
Title: COL4A6 is dispensable for autosomal recessive Alport syndrome.
Volume: 6
Pages: 29450
Publication
First Author: Korstanje R
Year: 2014
Journal: Kidney Int
Title: A mouse Col4a4 mutation causing Alport glomerulosclerosis with abnormal collagen α3α4α5(IV) trimers.
Volume: 85
Issue: 6
Pages: 1461-8
Publication
First Author: Stubbs JR
Year: 2012
Journal: J Bone Miner Res
Title: Longitudinal evaluation of FGF23 changes and mineral metabolism abnormalities in a mouse model of chronic kidney disease.
Volume: 27
Issue: 1
Pages: 38-46
Publication  
First Author: Kim JJ
Year: 2021
Journal: EBioMedicine
Title: Discoidin domain receptor 1 activation links extracellular matrix to podocyte lipotoxicity in Alport syndrome.
Volume: 63
Pages: 103162
Publication
First Author: Zeisberg M
Year: 2014
Journal: Am J Pathol
Title: Thrombospondin-1 deficiency causes a shift from fibroproliferative to inflammatory kidney disease and delays onset of renal failure.
Volume: 184
Issue: 10
Pages: 2687-98
Publication
First Author: Steenhard BM
Year: 2012
Journal: PLoS One
Title: Upregulated expression of integrin α1 in mesangial cells and integrin α3 and vimentin in podocytes of Col4a3-null (Alport) mice.
Volume: 7
Issue: 12
Pages: e50745
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Miyoshi T
Year: 2006
Journal: FASEB J
Title: Tumor-specific expression of the RGD-alpha3(IV)NC1 domain suppresses endothelial tube formation and tumor growth in mice.
Volume: 20
Issue: 11
Pages: 1904-6
Publication
First Author: LeBleu VS
Year: 2013
Journal: Nat Med
Title: Origin and function of myofibroblasts in kidney fibrosis.
Volume: 19
Issue: 8
Pages: 1047-53
Publication
First Author: Lin X
Year: 2014
Journal: J Am Soc Nephrol
Title: Feasibility of repairing glomerular basement membrane defects in Alport syndrome.
Volume: 25
Issue: 4
Pages: 687-92
Publication
First Author: Gomez IG
Year: 2015
Journal: J Clin Invest
Title: Anti-microRNA-21 oligonucleotides prevent Alport nephropathy progression by stimulating metabolic pathways.
Volume: 125
Issue: 1
Pages: 141-56
Publication
First Author: Wyss HM
Year: 2011
Journal: Am J Physiol Cell Physiol
Title: Biophysical properties of normal and diseased renal glomeruli.
Volume: 300
Issue: 3
Pages: C397-405
Publication
First Author: Miner JH
Year: 1996
Journal: J Cell Biol
Title: Molecular and functional defects in kidneys of mice lacking collagen alpha 3(IV): implications for Alport syndrome.
Volume: 135
Issue: 5
Pages: 1403-13
Publication
First Author: Zhang JJ
Year: 2012
Journal: J Immunol
Title: Murine membranous nephropathy: immunization with α3(IV) collagen fragment induces subepithelial immune complexes and FcγR-independent nephrotic syndrome.
Volume: 188
Issue: 7
Pages: 3268-77
Publication
First Author: Ryu M
Year: 2012
Journal: J Pathol
Title: Plasma leakage through glomerular basement membrane ruptures triggers the proliferation of parietal epithelial cells and crescent formation in non-inflammatory glomerular injury.
Volume: 228
Issue: 4
Pages: 482-94
Publication
First Author: Rao VH
Year: 2006
Journal: Am J Pathol
Title: Role for macrophage metalloelastase in glomerular basement membrane damage associated with alport syndrome.
Volume: 169
Issue: 1
Pages: 32-46
Publication
First Author: Andersen K
Year: 2017
Journal: J Am Soc Nephrol
Title: Intestinal Dysbiosis, Barrier Dysfunction, and Bacterial Translocation Account for CKD-Related Systemic Inflammation.
Volume: 28
Issue: 1
Pages: 76-83
Publication
First Author: Hanudel MR
Year: 2022
Journal: Sci Rep
Title: Renoprotective effects of ferric citrate in a mouse model of chronic kidney disease.
Volume: 12
Issue: 1
Pages: 6695
Publication
First Author: Ryu M
Year: 2011
Journal: Kidney Int
Title: Bacterial CpG-DNA accelerates Alport glomerulosclerosis by inducing an M1 macrophage phenotype and tumor necrosis factor-α-mediated podocyte loss.
Volume: 79
Issue: 2
Pages: 189-98
Publication
First Author: Wright MB
Year: 2021
Journal: Nat Commun
Title: Compounds targeting OSBPL7 increase ABCA1-dependent cholesterol efflux preserving kidney function in two models of kidney disease.
Volume: 12
Issue: 1
Pages: 4662
Publication
First Author: Kalluri R
Year: 2000
Journal: J Biol Chem
Title: Assembly of type IV collagen. Insights from alpha3(IV) collagen-deficient mice.
Volume: 275
Issue: 17
Pages: 12719-24
Publication  
First Author: Suh SH
Year: 2019
Journal: Int J Mol Sci
Title: Olmesartan Attenuates Kidney Fibrosis in a Murine Model of Alport Syndrome by Suppressing Tubular Expression of TGFβ.
Volume: 20
Issue: 15
Publication
First Author: Bae EH
Year: 2015
Journal: Am J Pathol
Title: Characterization of the intrarenal renin-angiotensin system in experimental alport syndrome.
Volume: 185
Issue: 5
Pages: 1423-35
Publication
First Author: Bollenbecker S
Year: 2023
Journal: Sci Rep
Title: Phosphate induces inflammation and exacerbates injury from cigarette smoke in the bronchial epithelium.
Volume: 13
Issue: 1
Pages: 4898
Publication  
First Author: Rubel D
Year: 2022
Journal: Cells
Title: Anti-microRNA-21 Therapy on Top of ACE Inhibition Delays Renal Failure in Alport Syndrome Mouse Models.
Volume: 11
Issue: 4
Publication
First Author: Cosgrove D
Year: 2007
Journal: Kidney Int
Title: Choosing a mouse model to study the molecular pathobiology of Alport glomerulonephritis.
Volume: 71
Issue: 7
Pages: 615-8
Publication
First Author: Ninichuk V
Year: 2006
Journal: Kidney Int
Title: Multipotent mesenchymal stem cells reduce interstitial fibrosis but do not delay progression of chronic kidney disease in collagen4A3-deficient mice.
Volume: 70
Issue: 1
Pages: 121-9
Publication
First Author: Gratton MA
Year: 2005
Journal: Am J Pathol
Title: Matrix metalloproteinase dysregulation in the stria vascularis of mice with Alport syndrome: implications for capillary basement membrane pathology.
Volume: 166
Issue: 5
Pages: 1465-74
Publication
First Author: Choi HS
Year: 2020
Journal: Sci Rep
Title: Angiotensin-[1-7] attenuates kidney injury in experimental Alport syndrome.
Volume: 10
Issue: 1
Pages: 4225
Publication
First Author: Sayers R
Year: 1999
Journal: Kidney Int
Title: Role for transforming growth factor-beta1 in alport renal disease progression.
Volume: 56
Issue: 5
Pages: 1662-73
Publication
First Author: Clauss S
Year: 2009
Journal: J Pathol
Title: Ccl2/Mcp-1 blockade reduces glomerular and interstitial macrophages but does not ameliorate renal pathology in collagen4A3-deficient mice with autosomal recessive Alport nephropathy.
Volume: 218
Issue: 1
Pages: 40-7
Publication
First Author: Iida M
Year: 2022
Journal: PLoS One
Title: TNF-α induces Claudin-1 expression in renal tubules in Alport mice.
Volume: 17
Issue: 3
Pages: e0265081
GXD Expression      
Probe: MGI:6444275
Assay Type: RT-PCR
Annotation Date: 2020-07-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:6444768
Age: postnatal week 5
Specimen Label: wild type control
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6444275
Assay Type: RT-PCR
Annotation Date: 2020-07-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:6444768
Age: postnatal week 5
Specimen Label: miR-183C
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3576056
Assay Type: RT-PCR
Annotation Date: 2005-05-03
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:3576070
Age: embryonic day 9.5
Image: 4
Specimen Label: a3 +/+
Specimen Num: 1
GXD Expression      
Probe: MGI:3576056
Assay Type: RT-PCR
Annotation Date: 2005-05-03
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:3576070
Age: embryonic day 9.5
Image: 4
Specimen Label: a3 -/-
Specimen Num: 2
GXD Expression      
Probe: MGI:3576056
Assay Type: RT-PCR
Annotation Date: 2005-05-03
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:3576070
Age: embryonic day 10.5
Image: 4
Specimen Label: a3 +/+
Specimen Num: 3
GXD Expression      
Probe: MGI:3576056
Assay Type: RT-PCR
Annotation Date: 2005-05-03
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:3576070
Age: embryonic day 10.5
Image: 4
Specimen Label: a3 -/-
Specimen Num: 4
GXD Expression      
Probe: MGI:6316043
Assay Type: Northern blot
Annotation Date: 2019-07-08
Strength: Present
Sex: Male
Emaps: EMAPS:1797227
Stage: TS27
Assay Id: MGI:6316312
Age: postnatal newborn
Specimen Label: 1
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6316043
Assay Type: Northern blot
Annotation Date: 2019-07-08
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6316312
Age: postnatal day 5
Specimen Label: 5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6316043
Assay Type: Northern blot
Annotation Date: 2019-07-08
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6316312
Age: postnatal day 10
Specimen Label: 10
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6316043
Assay Type: Northern blot
Annotation Date: 2019-07-08
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6316312
Age: postnatal day 20
Specimen Label: 20
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:6316043
Assay Type: Northern blot
Annotation Date: 2019-07-08
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6316312
Age: postnatal day 30
Specimen Label: 30
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:6316043
Assay Type: Northern blot
Annotation Date: 2019-07-08
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6316312
Age: postnatal day 40
Specimen Label: 40
Detected: true
Specimen Num: 6