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Search results 1 to 89 out of 89 for Hrnr

0.028s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: rat
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: The hornerin gene is a member of the "fused"gene family. Hornerin is a component of the epidermal cornified cell envelopes [].In humans, a number of genes specifying structural proteins expressed late during epidermal differentiation have been identified and found to be clustered on chromosome 1q21. Therefore, this region is named the epidermal differentiation complex (EDC). The proteins encoded by the EDC genes can be classified into three groups: the precursor proteins of the CE, the S100 family and the "fused"gene family []. In some classification, the "fused gene"family is classified as a subgroup within the S100 gene family []. The "fused"gene family members contain EF hands and internal tandem repeats. It consists of profilaggrin, trichohyalin, repetin, hornerin, the profilaggrin-related protein and cornulin (encoded by c1orf10). They are associated with keratin intermediate filaments and partially cross-linked to the cell envelope (CE) [].
Protein
Organism: Mus musculus/domesticus
Length: 872  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2496  
Fragment?: false
Publication
First Author: Krieg P
Year: 1997
Journal: Genomics
Title: Repetin (Rptn), a new member of the "fused gene" subgroup within the S100 gene family encoding a murine epidermal differentiation protein.
Volume: 43
Issue: 3
Pages: 339-48
Protein
Organism: Mus musculus/domesticus
Length: 3411  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 148  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 3234  
Fragment?: false
Publication
First Author: Huber M
Year: 2005
Journal: J Invest Dermatol
Title: Isolation and characterization of human repetin, a member of the fused gene family of the epidermal differentiation complex.
Volume: 124
Issue: 5
Pages: 998-1007
Publication
First Author: Henry J
Year: 2011
Journal: FASEB J
Title: Hornerin is a component of the epidermal cornified cell envelopes.
Volume: 25
Issue: 5
Pages: 1567-76
Publication
First Author: Rahrig S
Year: 2019
Journal: Allergy
Title: Transient epidermal barrier deficiency and lowered allergic threshold in filaggrin-hornerin (FlgHrnr(-/-) ) double-deficient mice.
Volume: 74
Issue: 7
Pages: 1327-1339
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Gutknecht MF
Year: 2017
Journal: Nat Commun
Title: Identification of the S100 fused-type protein hornerin as a regulator of tumor vascularity.
Volume: 8
Issue: 1
Pages: 552
GXD Expression    
Probe: MGI:4840081
Assay Type: Northern blot
Annotation Date: 2010-12-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:4840092
Age: postnatal adult
Image: 4
Specimen Label: 11
Detected: false
Specimen Num: 11
GXD Expression    
Probe: MGI:4840081
Assay Type: Northern blot
Annotation Date: 2010-12-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752822
Stage: TS22
Assay Id: MGI:4840091
Age: embryonic day 14.5
Image: 4
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:4840081
Assay Type: Northern blot
Annotation Date: 2010-12-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752823
Stage: TS23
Assay Id: MGI:4840091
Age: embryonic day 15.5
Image: 4
Specimen Label: 2
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:4840081
Assay Type: Northern blot
Annotation Date: 2010-12-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752824
Stage: TS24
Assay Id: MGI:4840091
Age: embryonic day 16.5
Image: 4
Specimen Label: 3
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5704394
Assay Type: RT-PCR
Annotation Date: 2016-01-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3272524
Stage: TS24
Assay Id: MGI:5704483
Age: embryonic day 16.5
Specimen Label: qPCR E16.5 wt
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5704394
Assay Type: RT-PCR
Annotation Date: 2016-01-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3272524
Stage: TS24
Assay Id: MGI:5704483
Age: embryonic day 16.5
Specimen Label: qPCR E16.5 Fzd6-/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:4840081
Assay Type: Northern blot
Annotation Date: 2010-12-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1762728
Stage: TS28
Assay Id: MGI:4840092
Age: postnatal adult
Image: 4
Specimen Label: 5
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:4840081
Assay Type: Northern blot
Annotation Date: 2010-12-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:4840092
Age: postnatal adult
Image: 4
Specimen Label: 2
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:4840081
Assay Type: Northern blot
Annotation Date: 2010-12-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:4840092
Age: postnatal adult
Image: 4
Specimen Label: 9
Detected: false
Specimen Num: 9
GXD Expression    
Probe: MGI:4840081
Assay Type: Northern blot
Annotation Date: 2010-12-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1691028
Stage: TS28
Assay Id: MGI:4840092
Age: postnatal adult
Image: 4
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:4840081
Assay Type: Northern blot
Annotation Date: 2010-12-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:4840092
Age: postnatal adult
Image: 4
Specimen Label: 8
Detected: false
Specimen Num: 8
GXD Expression    
Probe: MGI:4840081
Assay Type: Northern blot
Annotation Date: 2010-12-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3283428
Stage: TS28
Assay Id: MGI:4840092
Age: postnatal adult
Image: 4
Specimen Label: 6
Detected: false
Specimen Num: 6
GXD Expression    
Probe: MGI:4840081
Assay Type: Northern blot
Annotation Date: 2010-12-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:4840092
Age: postnatal adult
Image: 4
Specimen Label: 10
Detected: false
Specimen Num: 10
GXD Expression    
Probe: MGI:4840081
Assay Type: Northern blot
Annotation Date: 2010-12-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1893928
Stage: TS28
Assay Id: MGI:4840092
Age: postnatal adult
Image: 4
Specimen Label: 7
Detected: false
Specimen Num: 7
GXD Expression    
Probe: MGI:4840081
Assay Type: Northern blot
Annotation Date: 2010-12-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1718528
Stage: TS28
Assay Id: MGI:4840092
Age: postnatal adult
Image: 4
Specimen Label: 3
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:4840081
Assay Type: Northern blot
Annotation Date: 2010-12-02
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:4840092
Age: postnatal adult
Image: 4
Specimen Label: 12
Detected: false
Specimen Num: 12
GXD Expression    
Probe: MGI:4840081
Assay Type: Northern blot
Annotation Date: 2010-12-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1683328
Stage: TS28
Assay Id: MGI:4840092
Age: postnatal adult
Image: 4
Specimen Label: 4
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:4840081
Assay Type: Northern blot
Annotation Date: 2010-12-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:4840092
Age: postnatal adult
Image: 4
Specimen Label: 14
Detected: true
Specimen Num: 14
GXD Expression    
Probe: MGI:4840087
Assay Type: Western blot
Annotation Date: 2010-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752522
Stage: TS22
Assay Id: MGI:4840114
Age: embryonic day 14.5
Image: 6
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:4840087
Assay Type: Western blot
Annotation Date: 2010-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752523
Stage: TS23
Assay Id: MGI:4840114
Age: embryonic day 15.5
Image: 6
Specimen Label: 2
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:4840087
Assay Type: Western blot
Annotation Date: 2010-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752524
Stage: TS24
Assay Id: MGI:4840114
Age: embryonic day 16.5
Image: 6
Specimen Label: 3
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:4840087
Assay Type: Western blot
Annotation Date: 2010-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752525
Stage: TS25
Assay Id: MGI:4840114
Age: embryonic day 17.5
Image: 6
Specimen Label: 4
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:4840087
Assay Type: Western blot
Annotation Date: 2010-12-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752527
Stage: TS27
Assay Id: MGI:4840350
Age: postnatal day 3
Image: 6
Specimen Label: 1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4840084
Assay Type: Western blot
Annotation Date: 2010-12-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752527
Stage: TS27
Assay Id: MGI:4840351
Age: postnatal day 3
Image: 6
Specimen Label: 3
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:4840081
Assay Type: Northern blot
Annotation Date: 2010-12-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3557728
Stage: TS28
Assay Id: MGI:4840092
Age: postnatal adult
Image: 4
Specimen Label: 13
Detected: false
Specimen Num: 13
GXD Expression    
Probe: MGI:4840081
Assay Type: Northern blot
Annotation Date: 2010-12-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752722
Stage: TS22
Assay Id: MGI:4840091
Age: embryonic day 14.5
Image: 4
Specimen Label: 4
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:4840081
Assay Type: Northern blot
Annotation Date: 2010-12-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752723
Stage: TS23
Assay Id: MGI:4840091
Age: embryonic day 15.5
Image: 4
Specimen Label: 5
Detected: false
Specimen Num: 5
GXD Expression    
Probe: MGI:4840081
Assay Type: Northern blot
Annotation Date: 2010-12-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752724
Stage: TS24
Assay Id: MGI:4840091
Age: embryonic day 16.5
Image: 4
Specimen Label: 6
Detected: false
Specimen Num: 6
GXD Expression  
Probe: MGI:4840087
Assay Type: Immunohistochemistry
Annotation Date: 2010-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3278627
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:4840115
Age: postnatal day 3
Image: 7b
Specimen Label: 7b
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4840084
Assay Type: Immunohistochemistry
Annotation Date: 2010-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3278627
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:4840117
Age: postnatal day 3
Specimen Label: Not shown
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4840087
Assay Type: Immunohistochemistry
Annotation Date: 2010-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3278627
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:4840193
Age: postnatal day 3
Image: 8a,c,d
Specimen Label: 8a,c,d
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4840087
Assay Type: Immunohistochemistry
Annotation Date: 2010-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3278727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:4840115
Age: postnatal day 3
Image: 7b
Specimen Label: 7b
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4840084
Assay Type: Immunohistochemistry
Annotation Date: 2010-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3278727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:4840117
Age: postnatal day 3
Specimen Label: Not shown
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4840087
Assay Type: Immunohistochemistry
Annotation Date: 2010-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3278727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:4840193
Age: postnatal day 3
Image: 8a,c,d
Specimen Label: 8a,c,d
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:4840082
Assay Type: RNA in situ
Annotation Date: 2010-12-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752825
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:4840093
Age: embryonic day 17.5
Image: 5b
Note: Expresion is in the granular cornified layer.
Specimen Label: 5b
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4840082
Assay Type: RNA in situ
Annotation Date: 2010-12-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752827
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:4840093
Age: postnatal day 3
Specimen Label: Not shown
Detected: true
Specimen Num: 2
Publication
First Author: Makino T
Year: 2001
Journal: J Biol Chem
Title: Hornerin, a novel profilaggrin-like protein and differentiation-specific marker isolated from mouse skin.
Volume: 276
Issue: 50
Pages: 47445-52
Publication
First Author: Thyssen JP
Year: 2020
Journal: J Invest Dermatol
Title: Filaggrin Expression and Processing Deficiencies Impair Corneocyte Surface Texture and Stiffness in Mice.
Volume: 140
Issue: 3
Pages: 615-623.e5
Publication
First Author: Cui CY
Year: 2013
Journal: J Invest Dermatol
Title: Frizzled6 deficiency disrupts the differentiation process of nail development.
Volume: 133
Issue: 8
Pages: 1990-7
Publication
First Author: Ravasi T
Year: 2004
Journal: Genomics
Title: Probing the S100 protein family through genomic and functional analysis.
Volume: 84
Issue: 1
Pages: 10-22
Publication
First Author: Kumar V
Year: 2015
Journal: J Cell Biol
Title: A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity.
Volume: 211
Issue: 5
Pages: 1057-75
Publication
First Author: Nagamachi A
Year: 2013
Journal: Cancer Cell
Title: Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7.
Volume: 24
Issue: 3
Pages: 305-17
Publication      
First Author: European Mouse Mutant Archive
Year: 2003
Journal: Unpublished
Title: Information obtained from the European Mouse Mutant Archive (EMMA)
Publication
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
Publication      
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication        
First Author: Haiming Tang, Dustin Ebert, Matthias Blum, Robert Finn, Paul Thomas
Year: 2023
Title: TreeGrafter-generated GO annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
Publication        
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7