|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 201 to 283 out of 283 for Rpgr

<< First    < Previous  |  Next >    Last >>
0.047s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
•
•
•
•
•
Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
•
•
•
•
•
Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
•
•
•
•
•
Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
•
•
•
•
•
Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
•
•
•
•
•
Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
•
•
•
•
•
Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
•
•
•
•
•
Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
•
•
•
•
•
Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
•
•
•
•
•
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
•
•
•
•
•
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
•
•
•
•
•
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
•
•
•
•
•
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
•
•
•
•
•
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
•
•
•
•
•
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
•
•
•
•
•
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
•
•
•
•
•
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
•
•
•
•
•
Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
•
•
•
•
•
Gene
108704962 | rpgrip1.S
Type: gene
Organism: frog, African clawed
•
•
•
•
•
Gene
108714961 | rpgrip1.L
Type: gene
Organism: frog, African clawed
•
•
•
•
•
Publication
23351659 | J:196617
First Author: Rachel RA
Year: 2012
Journal: Cilia
Title: Photoreceptor sensory cilia and ciliopathies: focus on CEP290, RPGR and their interacting proteins.
Volume: 1
Issue: 1
Pages: 22
•
•
•
•
•
Publication
22825473 | J:315239
 
First Author: Patil H
Year: 2012
Journal: Cell Death Dis
Title: Selective loss of RPGRIP1-dependent ciliary targeting of NPHP4, RPGR and SDCCAG8 underlies the degeneration of photoreceptor neurons.
Volume: 3
Pages: e355
•
•
•
•
•
Publication
23213406 | -
First Author: Patil H
Year: 2012
Journal: Biol Open
Title: Structural and functional plasticity of subcellular tethering, targeting and processing of RPGRIP1 by RPGR isoforms.
Volume: 1
Issue: 2
Pages: 140-60
•
•
•
•
•
Allele
Rpgr<Rd9> | MGI:3511481
Name: retinitis pigmentosa GTPase regulator; retinal degeneration 9
Allele Type: Spontaneous
Attribute String: Modified isoform(s)
•
•
•
•
•
Genotype
Genotype
Symbol: Rpgr/?
Background: C57BL/6-Rpgr
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Allele
Tg(CAG-Rpgr)mRDefWrght | MGI:4936750
Name: transgene insertion mRDef, Rachel Wright
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
•
•
•
•
•
Genotype
Genotype
Symbol: Rpgr/Rpgr Tg(CMV-Rpgr)1Tili/?
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Allele
Rpgr<tm1Tili> | MGI:2386674
Name: retinitis pigmentosa GTPase regulator; targeted mutation 1, Tiansen Li
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
•
•
•
•
•
Interaction Experiment
Hong DH (2001)
Description: Retinitis pigmentosa GTPase regulator (RPGRr)-interacting protein is stably associated with the photoreceptor ciliary axoneme and anchors RPGR to the connecting cilium.
•
•
•
•
•
Transgene
MGI:4936752 | Tg(CAG-Rpgr)mRDefWrght
Type: transgene
Organism: mouse, laboratory
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(CAG-Rpgr)mRDefWrght/? Rpgr/Rpgr
Background: involves: 129S4/SvJae * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(CAG-Rpgr)mRDefWrght/?
Background: C57BL/6-Tg(CAG-Rpgr)mRDefWrght
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
DO Term
DOID:0110414 | retinitis pigmentosa 3
•
•
•
•
•
Genotype
Genotype
Symbol: Rpgr/Rpgr
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Publication
12140192 | -
First Author: Mavlyutov TA
Year: 2002
Journal: Hum Mol Genet
Title: Species-specific subcellular localization of RPGR and RPGRIP isoforms: implications for the phenotypic variability of congenital retinopathies among species.
Volume: 11
Issue: 16
Pages: 1899-907
•
•
•
•
•
Transgene
MGI:3038635 | Tg(CMV-Rpgr)1Tili
Type: transgene
Organism: mouse, laboratory
•
•
•
•
•
DO Term
DOID:0111008 | X-linked cone-rod dystrophy 1
•
•
•
•
•
DO Term
DOID:0112157 | X-linked atrophic macular degeneration
•
•
•
•
•
Publication
10958648 | -
First Author: Roepman R
Year: 2000
Journal: Hum Mol Genet
Title: The retinitis pigmentosa GTPase regulator (RPGR) interacts with novel transport-like proteins in the outer segments of rod photoreceptors.
Volume: 9
Issue: 14
Pages: 2095-105
•
•
•
•
•
Publication
25414380 | -
 
First Author: Li T
Year: 2014
Journal: Cold Spring Harb Perspect Med
Title: Leber congenital amaurosis caused by mutations in RPGRIP1.
Volume: 5
Issue: 4
•
•
•
•
•
Protein Domain
IPR031134 | RPGRIP1
Type: Family
Description: Retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGRIP1) specifically interacts with retinitis pigmentosa GTPase regulator (RPGR) []. Mutations in RPGR cause X-linked retinitis pigmentosa type 3 (RP3), whereas mutations in RPGRIP1 cause Leber congenital amaurosis (LCA) []. RPGRIP1 is expressed in the retina and is present in the connecting cilium and outer segments of photoreceptors, where it partially co-localises with RPGR [, ]. RPGR isoforms seem to determine the subcellular targeting of RPGRIP1 [].
•
•
•
•
•
GO Term
GO:0120206 | photoreceptor distal connecting cilium
•
•
•
•
•
DO Term
DOID:0112124 | X-linked retinitis pigmentosa and sinorespiratory infections
•
•
•
•
•
Gene
9657 | IQCB1
Type: gene
Organism: human
•
•
•
•
•
Allele
Tg(CMV-Rpgr)1Tili | MGI:3038604
Name: transgene insertion 1, Tiansen Li
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
•
•
•
•
•
Gene
23322 | RPGRIP1L
Type: gene
Organism: human
•
•
•
•
•
Publication
10452952 | -
First Author: Wang W
Year: 1999
Journal: Gene
Title: Molecular characterization and mapping of canine cGMP-phosphodiesterase delta subunit (PDE6D).
Volume: 236
Issue: 2
Pages: 325-32
•
•
•
•
•
Publication
14561760 | J:87331
First Author: Zhang H
Year: 2004
Journal: J Biol Chem
Title: Photoreceptor cGMP phosphodiesterase delta subunit (PDEdelta) functions as a prenyl-binding protein.
Volume: 279
Issue: 1
Pages: 407-13
•
•
•
•
•
Publication
18503409 | -
First Author: Day JP
Year: 2008
Journal: Biochem J
Title: Regulation of a Drosophila melanogaster cGMP-specific phosphodiesterase by prenylation and interaction with a prenyl-binding protein.
Volume: 414
Issue: 3
Pages: 363-74
•
•
•
•
•
Protein Domain
IPR017287 | Rhodop-sen_GMP-Pdiesterase_dsu
Type: Family
Description: Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase () is an oligomer composed of two catalytic chains (alpha and beta), an inhibitory chain (gamma) and a delta chain. This protein interacts with RPGR (retinitis pigmentosa GTPase regulator) [], ARL2 (Arf-like-2) and ARL3. This entry represents the delta subunit [], which is thought to act as a prenyl-binding protein []and participates in the transport of PDE6 catalytic alpha/beta subunits [].
•
•
•
•
•
Protein
M0QWC0
Organism: Mus musculus/domesticus
Length: 289  
Fragment?: false
•
•
•
•
•
Protein
M0QW56
Organism: Mus musculus/domesticus
Length: 191  
Fragment?: true
•
•
•
•
•
Protein
Q5D222
Organism: Mus musculus/domesticus
Length: 553  
Fragment?: false
•
•
•
•
•
Protein
M0QWI1
Organism: Mus musculus/domesticus
Length: 91  
Fragment?: true
•
•
•
•
•
Strain
MGI:3720099 | C57BL/6-Rpgr<Rd9>
Attribute String: spontaneous mutation, mutant strain, coisogenic
•
•
•
•
•
Strain
MGI:2173875 | C57BL/6J-Rpgr<Rd9>/BocJ
Attribute String: spontaneous mutation, mutant strain, coisogenic
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(CMV-Rpgr)1Tili/Tg(CMV-Rpgr)1Tili
Background: involves: C57BL/6
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(CMV-Rpgr)1Tili/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Rpgr/Rpgr<+>
Background: C57BL/6-Rpgr
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Rpgr/Rpgr
Background: C57BL/6-Rpgr
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Protein
M0QWT5
Organism: Mus musculus/domesticus
Length: 71  
Fragment?: true
•
•
•
•
•
Publication
23559067 | J:200445
First Author: Wätzlich D
Year: 2013
Journal: EMBO Rep
Title: The interplay between RPGR, PDEδ and Arl2/3 regulate the ciliary targeting of farnesylated cargo.
Volume: 14
Issue: 5
Pages: 465-72
•
•
•
•
•
Protein
M0QW58
Organism: Mus musculus/domesticus
Length: 201  
Fragment?: true
•
•
•
•
•
Protein
M0QWL3
Organism: Mus musculus/domesticus
Length: 82  
Fragment?: true
•
•
•
•
•
Protein
M0QWM1
Organism: Mus musculus/domesticus
Length: 295  
Fragment?: true
•
•
•
•
•
Publication
26358772 | J:226494
First Author: Mookherjee S
Year: 2015
Journal: Hum Mol Genet
Title: Long-term rescue of cone photoreceptor degeneration in retinitis pigmentosa 2 (RP2)-knockout mice by gene replacement therapy.
Volume: 24
Issue: 22
Pages: 6446-58
•
•
•
•
•
Publication
35368022 | J:323103
First Author: Lu J
Year: 2022
Journal: Sci Rep
Title: Spata7 is required for maintenance of the retinal connecting cilium.
Volume: 12
Issue: 1
Pages: 5575
•
•
•
•
•
Publication
32330228 | J:288418
First Author: Hu S
Year: 2020
Journal: Invest Ophthalmol Vis Sci
Title: In Vivo CRISPR/Cas9-Mediated Genome Editing Mitigates Photoreceptor Degeneration in a Mouse Model of X-Linked Retinitis Pigmentosa.
Volume: 61
Issue: 4
Pages: 31
•
•
•
•
•
Protein Coding Gene
MGI:2144877 | Spata7
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein
Q9EPQ2
Organism: Mus musculus/domesticus
Length: 1331  
Fragment?: false
•
•
•
•
•
Protein
Q0VGR8
Organism: Mus musculus/domesticus
Length: 1126  
Fragment?: false
•
•
•
•
•
Protein
E9QQ97
Organism: Mus musculus/domesticus
Length: 1127  
Fragment?: false
•
•
•
•
•
Protein
E7CHD7
Organism: Mus musculus/domesticus
Length: 1320  
Fragment?: false
•
•
•
•
•
Publication
16123399 | J:101340
First Author: Pawlyk BS
Year: 2005
Journal: Invest Ophthalmol Vis Sci
Title: Gene replacement therapy rescues photoreceptor degeneration in a murine model of Leber congenital amaurosis lacking RPGRIP.
Volume: 46
Issue: 9
Pages: 3039-45
•
•
•
•
•
Protein Coding Gene
MGI:1932134 | Rpgrip1
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Publication
29669747 | J:265696
First Author: Jobling AI
Year: 2018
Journal: J Neurosci
Title: The Role of the Microglial Cx3cr1 Pathway in the Postnatal Maturation of Retinal Photoreceptors.
Volume: 38
Issue: 20
Pages: 4708-4723
•
•
•
•
•
Protein Coding Gene
MGI:1858233 | Nphp1
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:2384210 | Nphp4
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:87971 | Ahi1
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein
O55057
Organism: Mus musculus/domesticus
Length: 150  
Fragment?: false
•
•
•
•
•
Protein
Q3URU9
Organism: Mus musculus/domesticus
Length: 150  
Fragment?: false
•
•
•
•
•
Protein
Q3TDQ8
Organism: Mus musculus/domesticus
Length: 150  
Fragment?: false
•
•
•
•
•
Protein Coding Gene
MGI:2384917 | Cep290
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom