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Search results 301 to 400 out of 423 for Pdpk1

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Type Details Score
Publication
First Author: Bayascas JR
Year: 2005
Journal: Curr Biol
Title: Hypomorphic mutation of PDK1 suppresses tumorigenesis in PTEN(+/-) mice.
Volume: 15
Issue: 20
Pages: 1839-46
Publication
First Author: Scortegagna M
Year: 2014
Journal: Oncogene
Title: Genetic inactivation or pharmacological inhibition of Pdk1 delays development and inhibits metastasis of Braf(V600E)::Pten(-/-) melanoma.
Volume: 33
Issue: 34
Pages: 4330-9
Publication
First Author: Rodriguez OC
Year: 2009
Journal: Am J Pathol
Title: A reduction in Pten tumor suppressor activity promotes ErbB-2-induced mouse prostate adenocarcinoma formation through the activation of signaling cascades downstream of PDK1.
Volume: 174
Issue: 6
Pages: 2051-60
Publication
First Author: Wullschleger S
Year: 2011
Journal: Dis Model Mech
Title: How moderate changes in Akt T-loop phosphorylation impact on tumorigenesis and insulin resistance.
Volume: 4
Issue: 1
Pages: 95-103
Publication
First Author: Finlay DK
Year: 2009
Journal: J Exp Med
Title: Phosphoinositide-dependent kinase 1 controls migration and malignant transformation but not cell growth and proliferation in PTEN-null lymphocytes.
Volume: 206
Issue: 11
Pages: 2441-54
Publication
First Author: Mora A
Year: 2005
Journal: FEBS Lett
Title: Role of the PDK1-PKB-GSK3 pathway in regulating glycogen synthase and glucose uptake in the heart.
Volume: 579
Issue: 17
Pages: 3632-8
Publication
First Author: Fishwick KJ
Year: 2010
Journal: Dev Biol
Title: Initiation of neuronal differentiation requires PI3-kinase/TOR signalling in the vertebrate neural tube.
Volume: 338
Issue: 2
Pages: 215-25
Publication
First Author: Zheng W
Year: 2010
Journal: EMBO Rep
Title: Maternal phosphatidylinositol 3-kinase signalling is crucial for embryonic genome activation and preimplantation embryogenesis.
Volume: 11
Issue: 11
Pages: 890-5
Publication
First Author: Yang M
Year: 2015
Journal: J Exp Med
Title: PDK1 orchestrates early NK cell development through induction of E4BP4 expression and maintenance of IL-15 responsiveness.
Volume: 212
Issue: 2
Pages: 253-65
Publication
First Author: Di R
Year: 2012
Journal: Biochem J
Title: S6K inhibition renders cardiac protection against myocardial infarction through PDK1 phosphorylation of Akt.
Volume: 441
Issue: 1
Pages: 199-207
Publication
First Author: Lee CR
Year: 2016
Journal: Cell Rep
Title: Myeloid-Derived Suppressor Cells Are Controlled by Regulatory T Cells via TGF-β during Murine Colitis.
Volume: 17
Issue: 12
Pages: 3219-3232
Publication
First Author: Yang S
Year: 2022
Journal: Diabetologia
Title: MicroRNA-193b impairs muscle growth in mouse models of type 2 diabetes by targeting the PDK1/Akt signalling pathway.
Volume: 65
Issue: 3
Pages: 563-581
Publication
First Author: Du L
Year: 2016
Journal: Oncogene
Title: Overexpression of PIK3CA in murine head and neck epithelium drives tumor invasion and metastasis through PDK1 and enhanced TGFβ signaling.
Volume: 35
Issue: 35
Pages: 4641-52
Publication
First Author: Torbett NE
Year: 2003
Journal: J Biol Chem
Title: Hyperosmotic-induced protein kinase N 1 activation in a vesicular compartment is dependent upon Rac1 and 3-phosphoinositide-dependent kinase 1.
Volume: 278
Issue: 34
Pages: 32344-51
Publication
First Author: Yang SJ
Year: 2013
Journal: PLoS One
Title: Activation of Akt by advanced glycation end products (AGEs): involvement of IGF-1 receptor and caveolin-1.
Volume: 8
Issue: 3
Pages: e58100
Publication
First Author: Tominaga Y
Year: 2005
Journal: Mol Cell Biol
Title: Translational deregulation in PDK-1-/- embryonic stem cells.
Volume: 25
Issue: 19
Pages: 8465-75
Publication
First Author: Liu HX
Year: 2013
Journal: PLoS One
Title: PPARβ Regulates Liver Regeneration by Modulating Akt and E2f Signaling.
Volume: 8
Issue: 6
Pages: e65644
Publication
First Author: Schönhuber N
Year: 2014
Journal: Nat Med
Title: A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer.
Volume: 20
Issue: 11
Pages: 1340-1347
Publication
First Author: Goertz MJ
Year: 2011
Journal: J Clin Invest
Title: Foxo1 is required in mouse spermatogonial stem cells for their maintenance and the initiation of spermatogenesis.
Volume: 121
Issue: 9
Pages: 3456-66
Publication
First Author: Itoh Y
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: PDK1-Akt pathway regulates radial neuronal migration and microtubules in the developing mouse neocortex.
Volume: 113
Issue: 21
Pages: E2955-64
Publication
First Author: Watatani K
Year: 2012
Journal: Genes Cells
Title: PDK1 regulates the generation of oligodendrocyte precursor cells at an early stage of mouse telencephalic development.
Volume: 17
Issue: 4
Pages: 326-35
Publication
First Author: McGuire VA
Year: 2013
Journal: Mol Cell Biol
Title: Cross talk between the Akt and p38α pathways in macrophages downstream of Toll-like receptor signaling.
Volume: 33
Issue: 21
Pages: 4152-65
Publication
First Author: Eser S
Year: 2013
Journal: Cancer Cell
Title: Selective requirement of PI3K/PDK1 signaling for Kras oncogene-driven pancreatic cell plasticity and cancer.
Volume: 23
Issue: 3
Pages: 406-20
Publication
First Author: Inoue H
Year: 2006
Journal: Cell Metab
Title: Role of hepatic STAT3 in brain-insulin action on hepatic glucose production.
Volume: 3
Issue: 4
Pages: 267-75
Publication
First Author: Macintyre AN
Year: 2011
Journal: Immunity
Title: Protein kinase B controls transcriptional programs that direct cytotoxic T cell fate but is dispensable for T cell metabolism.
Volume: 34
Issue: 2
Pages: 224-36
Publication
First Author: Schweighoffer E
Year: 2013
Journal: Immunity
Title: The BAFF receptor transduces survival signals by co-opting the B cell receptor signaling pathway.
Volume: 38
Issue: 3
Pages: 475-88
Publication
First Author: Oh YJ
Year: 2009
Journal: J Immunol
Title: HMGB1 is phosphorylated by classical protein kinase C and is secreted by a calcium-dependent mechanism.
Volume: 182
Issue: 9
Pages: 5800-9
Publication
First Author: Sun F
Year: 2022
Journal: Cell Death Dis
Title: SUMOylation of PDPK1 Is required to maintain glycolysis-dependent CD4 T-cell homeostasis.
Volume: 13
Issue: 2
Pages: 181
Publication
First Author: Yang ZH
Year: 2020
Journal: Mol Cell
Title: A Non-canonical PDK1-RSK Signal Diminishes Pro-caspase-8-Mediated Necroptosis Blockade.
Volume: 80
Issue: 2
Pages: 296-310.e6
Publication
First Author: Orlacchio A
Year: 2017
Journal: Cancer Res
Title: SGK1 Is a Critical Component of an AKT-Independent Pathway Essential for PI3K-Mediated Tumor Development and Maintenance.
Volume: 77
Issue: 24
Pages: 6914-6926
Publication
First Author: Feng Q
Year: 2010
Journal: Mol Cell Biol
Title: PDK1 regulates vascular remodeling and promotes epithelial-mesenchymal transition in cardiac development.
Volume: 30
Issue: 14
Pages: 3711-21
Publication
First Author: Iskandar K
Year: 2010
Journal: Am J Physiol Endocrinol Metab
Title: PDK-1/FoxO1 pathway in POMC neurons regulates Pomc expression and food intake.
Volume: 298
Issue: 4
Pages: E787-98
Publication
First Author: Zhang S
Year: 2021
Journal: Cell Death Dis
Title: TMEM116 is required for lung cancer cell motility and metastasis through PDK1 signaling pathway.
Volume: 12
Issue: 12
Pages: 1086
Publication
First Author: Remy I
Year: 2004
Journal: Mol Cell Biol
Title: Regulation of apoptosis by the Ft1 protein, a new modulator of protein kinase B/Akt.
Volume: 24
Issue: 4
Pages: 1493-504
Publication
First Author: Liao J
Year: 2021
Journal: Cell Rep
Title: Prenatal correction of IGF2 to rescue the growth phenotypes in mouse models of Beckwith-Wiedemann and Silver-Russell syndromes.
Volume: 34
Issue: 6
Pages: 108729
Publication      
First Author: Cordón-Barris L
Year: 2016
Journal: Mol Cell Biol
Title: Mutation of the 3-phosphoinositide-dependent protein kinase-1 (PDK1) substrate-docking site in the developing brain causes microcephaly with abnormal brain morphogenesis independently of Akt, leading to impaired cognition and disruptive behaviors.
Publication
First Author: Olthof AM
Year: 2021
Journal: Nucleic Acids Res
Title: Disruption of exon-bridging interactions between the minor and major spliceosomes results in alternative splicing around minor introns.
Volume: 49
Issue: 6
Pages: 3524-3545
Publication
First Author: Zurashvili T
Year: 2013
Journal: Mol Cell Biol
Title: Interaction of PDK1 with phosphoinositides is essential for neuronal differentiation but dispensable for neuronal survival.
Volume: 33
Issue: 5
Pages: 1027-40
Publication
First Author: Zheng Y
Year: 2016
Journal: Leukemia
Title: Loss of Dnmt3b accelerates MLL-AF9 leukemia progression.
Volume: 30
Issue: 12
Pages: 2373-2384
Publication
First Author: Nadra K
Year: 2006
Journal: Mol Cell Biol
Title: Differentiation of trophoblast giant cells and their metabolic functions are dependent on peroxisome proliferator-activated receptor beta/delta.
Volume: 26
Issue: 8
Pages: 3266-81
Publication
First Author: Hryciw T
Year: 2010
Journal: J Neurochem
Title: The fibroblast growth factor receptor substrate 3 adapter is a developmentally regulated microtubule-associated protein expressed in migrating and differentiated neurons.
Volume: 112
Issue: 4
Pages: 924-39
Publication
First Author: Zamfirescu RC
Year: 2021
Journal: Am J Physiol Cell Physiol
Title: mTORC1/2 signaling is downregulated by amino acid-free culture of mouse preimplantation embryos and is only partially restored by amino acid readdition.
Volume: 320
Issue: 1
Pages: C30-C44
Publication
First Author: Westmoreland JJ
Year: 2009
Journal: Dev Biol
Title: Pdk1 activity controls proliferation, survival, and growth of developing pancreatic cells.
Volume: 334
Issue: 1
Pages: 285-98
Publication
First Author: Darido C
Year: 2011
Journal: Cancer Cell
Title: Targeting of the tumor suppressor GRHL3 by a miR-21-dependent proto-oncogenic network results in PTEN loss and tumorigenesis.
Volume: 20
Issue: 5
Pages: 635-48
Publication
First Author: Oishi K
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Selective induction of neocortical GABAergic neurons by the PDK1-Akt pathway through activation of Mash1.
Volume: 106
Issue: 31
Pages: 13064-9
Publication
First Author: Wei Y
Year: 2020
Journal: Mol Brain
Title: PDK1 regulates the survival of the developing cortical interneurons.
Volume: 13
Issue: 1
Pages: 65
Publication
First Author: Xu M
Year: 2019
Journal: Cereb Cortex
Title: PDK1 Deficit Impairs the Development of the Dentate Gyrus in Mice.
Volume: 29
Issue: 3
Pages: 1185-1198
Publication
First Author: Lee MJ
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: RGS4 and RGS5 are in vivo substrates of the N-end rule pathway.
Volume: 102
Issue: 42
Pages: 15030-5
Publication
First Author: Di-Poï N
Year: 2005
Journal: Mol Cell Biol
Title: Epithelium-mesenchyme interactions control the activity of peroxisome proliferator-activated receptor beta/delta during hair follicle development.
Volume: 25
Issue: 5
Pages: 1696-712
Publication
First Author: Inoue T
Year: 2011
Journal: Stem Cell Rev
Title: APOA-1 is a novel marker of erythroid cell maturation from hematopoietic stem cells in mice and humans.
Volume: 7
Issue: 1
Pages: 43-52
Publication
First Author: Chen X
Year: 2010
Journal: Mol Endocrinol
Title: The cooperative function of nuclear receptor coactivator 1 (NCOA1) and NCOA3 in placental development and embryo survival.
Volume: 24
Issue: 10
Pages: 1917-34
Publication
First Author: Dainichi T
Year: 2016
Journal: Cell Rep
Title: PDK1 Is a Regulator of Epidermal Differentiation that Activates and Organizes Asymmetric Cell Division.
Volume: 15
Issue: 8
Pages: 1615-23
Publication
First Author: Childress P
Year: 2015
Journal: Mol Endocrinol
Title: Genome-Wide Mapping and Interrogation of the Nmp4 Antianabolic Bone Axis.
Volume: 29
Issue: 9
Pages: 1269-85
Publication
First Author: Wajapeyee N
Year: 2013
Journal: Genes Dev
Title: Oncogenic RAS directs silencing of tumor suppressor genes through ordered recruitment of transcriptional repressors.
Volume: 27
Issue: 20
Pages: 2221-6
Publication  
First Author: Himmels P
Year: 2017
Journal: Nat Commun
Title: Motor neurons control blood vessel patterning in the developing spinal cord.
Volume: 8
Pages: 14583
Publication
First Author: Han X
Year: 2020
Journal: Cereb Cortex
Title: PDK1 Regulates Transition Period of Apical Progenitors to Basal Progenitors by Controlling Asymmetric Cell Division.
Volume: 30
Issue: 1
Pages: 406-420
Publication
First Author: Luo W
Year: 2015
Journal: Development
Title: Akt1 signaling coordinates BMP signaling and β-catenin activity to regulate second heart field progenitor development.
Volume: 142
Issue: 4
Pages: 732-42
Publication
First Author: Munton RP
Year: 2007
Journal: Mol Cell Proteomics
Title: Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.
Volume: 6
Issue: 2
Pages: 283-93
Publication
First Author: Li S
Year: 2016
Journal: Biol Reprod
Title: Ggnbp2 Is Essential for Pregnancy Success via Regulation of Mouse Trophoblast Stem Cell Proliferation and Differentiation.
Volume: 94
Issue: 2
Pages: 41
Publication  
First Author: Koutelou E
Year: 2019
Journal: Development
Title: USP22 controls multiple signaling pathways that are essential for vasculature formation in the mouse placenta.
Volume: 146
Issue: 4
Publication      
First Author: Lexicon Genetics Inc
Year: 2005
Journal: MGI Direct Data Submission
Title: NIH initiative supporting placement of Lexicon Genetics, Inc. mice into public repositories
Publication        
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
UniProt Feature
Begin: 305
Description: Phosphothreonine; by PDPK1
Type: modified residue
End: 305
UniProt Feature
Begin: 309
Description: Phosphothreonine; by PDPK1
Type: modified residue
End: 309
UniProt Feature
Begin: 198
Description: Phosphothreonine; by PDPK1
Type: modified residue
End: 198
UniProt Feature
Begin: 513
Description: Phosphothreonine; by PDPK1
Type: modified residue
End: 513