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Search results 201 to 258 out of 258 for Osm

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0.038s

Type

Details

Score

Publication

20229348 | -

First Author:	Wang Y
Year:	1999
Journal:	Sci China C Life Sci
Title:	cDNA cloning and expression of an apoptosis-related gene, humanTFAR15 gene.
Volume:	42
Issue:	3
Pages:	323-9

•

Protein Domain

IPR009652 | PDCD10

Type:

Family

Description:

Programmed cell death 10 protein (PDCD10/CCM3) is part of the CCM complex and is required for neuronal migration []. It also has roles outside of this complex [], it is crucial in vascularization and in angiogenesis as it functions in vessel permeability and stability []. PDCD10/CCM3 was originally discovered to be upregulated during granulocyte apoptosis and is thought to play a role in cell death []. However, a specific role for PDCD10 in cell survival is not clear as both pro-survival and pro-apoptotic effects have been reported [, ]. PDCD10/CCM3 contains an N-terminal dimerisation domain and a C-terminal focal adhesion targeting-homology (FAT-H) domain [].There are three CCM proteins: CCM1 (also known as KRIT1), CCM2 (also known as OSM and malcavernin) and CCM3 (also known as PDCD10). Mutations in the genes encoding CCM proteins cause cerebral cavernous malformations (CCMs), a disease characterised by dilated leaky blood vessels, especially in the neurovasculature, that result in increased risk of stroke, focal neurological defects and seizures. The CCM proteins can form a trimeric complex. They can also interact with a range of signaling, cytoskeletal and adaptor proteins that may account for their roles in a range of basic cellular processes including cell adhesion, migration, polarity and apoptosis [].

•

Protein Coding Gene

MGI:1330819 | Osmr

Type:	protein_coding_gene
Organism:	mouse, laboratory

•

Publication

9584176 | J:47670

First Author:	Lindberg RA
Year:	1998
Journal:	Mol Cell Biol
Title:	Cloning and characterization of a specific receptor for mouse oncostatin M.
Volume:	18
Issue:	6
Pages:	3357-67

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Publication

10455148 | J:57022

First Author:	Nakayama K
Year:	1999
Journal:	J Biol Chem
Title:	A novel oncostatin M-inducible gene OIG37 forms a gene family with MyD118 and GADD45 and negatively regulates cell growth.
Volume:	274
Issue:	35
Pages:	24766-72

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Publication

18981146 | J:141077

First Author:	Mozaffarian A
Year:	2008
Journal:	J Immunol
Title:	Mechanisms of oncostatin M-induced pulmonary inflammation and fibrosis.
Volume:	181
Issue:	10
Pages:	7243-53

•

Publication

23760954 | J:198637

First Author:	Minchin JE
Year:	2013
Journal:	Development
Title:	Oesophageal and sternohyal muscle fibres are novel Pax3-dependent migratory somite derivatives essential for ingestion.
Volume:	140
Issue:	14
Pages:	2972-84

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Publication

24695736 | J:214124

First Author:	Komori T
Year:	2014
Journal:	J Biol Chem
Title:	Deficiency of oncostatin M receptor β (OSMRβ) exacerbates high-fat diet-induced obesity and related metabolic disorders in mice.
Volume:	289
Issue:	20
Pages:	13821-37

•

Publication

16410783 | J:106761

First Author:	Goren I
Year:	2006
Journal:	J Invest Dermatol
Title:	Oncostatin M expression is functionally connected to neutrophils in the early inflammatory phase of skin repair: implications for normal and diabetes-impaired wounds.
Volume:	126
Issue:	3
Pages:	628-37

•

Publication

12855584 | J:86261

First Author:	Tanaka M
Year:	2003
Journal:	Blood
Title:	Targeted disruption of oncostatin M receptor results in altered hematopoiesis.
Volume:	102
Issue:	9
Pages:	3154-62

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Publication

28258089 | J:241513

First Author:	Zhang X
Year:	2017
Journal:	J Lipid Res
Title:	Oncostatin M receptor β deficiency attenuates atherogenesis by inhibiting JAK2/STAT3 signaling in macrophages.
Volume:	58
Issue:	5
Pages:	895-906

•

Publication

33051515 | J:299046

First Author:	Yamashita S
Year:	2020
Journal:	Sci Rep
Title:	Essential roles of oncostatin M receptor β signaling in renal crystal formation in mice.
Volume:	10
Issue:	1
Pages:	17150

•

Publication

37120549 | J:336118

First Author:	Feng Y
Year:	2023
Journal:	J Transl Med
Title:	OSMR deficiency aggravates pressure overload-induced cardiac hypertrophy by modulating macrophages and OSM/LIFR/STAT3 signalling.
Volume:	21
Issue:	1
Pages:	290

•

Publication

23760275 | J:201766

First Author:	Komori T
Year:	2013
Journal:	J Biol Chem
Title:	Lack of oncostatin M receptor β leads to adipose tissue inflammation and insulin resistance by switching macrophage phenotype.
Volume:	288
Issue:	30
Pages:	21861-75

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Publication

34301760 | J:310829

First Author:	Nguyen-Tran HH
Year:	2021
Journal:	Cancer Res
Title:	Endothelial Reprogramming Stimulated by Oncostatin M Promotes Inflammation and Tumorigenesis in VHL-Deficient Kidney Tissue.
Volume:	81
Issue:	19
Pages:	5060-5073

•

Publication

14999682 | J:105527

First Author:	Nakamura K
Year:	2004
Journal:	Hepatology
Title:	Hepatocyte proliferation and tissue remodeling is impaired after liver injury in oncostatin M receptor knockout mice.
Volume:	39
Issue:	3
Pages:	635-44

•

Publication

18641356 | J:139227

First Author:	Hams E
Year:	2008
Journal:	J Immunol
Title:	Oncostatin M receptor-beta signaling limits monocytic cell recruitment in acute inflammation.
Volume:	181
Issue:	3
Pages:	2174-80

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Publication

25751817 | J:227930

First Author:	Lörchner H
Year:	2015
Journal:	Nat Med
Title:	Myocardial healing requires Reg3β-dependent accumulation of macrophages in the ischemic heart.
Volume:	21
Issue:	4
Pages:	353-62

•

Publication

20956341 | J:165780

First Author:	Bilsborough J
Year:	2010
Journal:	J Immunol
Title:	IL-31 receptor (IL-31RA) knockout mice exhibit elevated responsiveness to oncostatin M.
Volume:	185
Issue:	10
Pages:	6023-30

•

Publication

12891556 | J:98441

First Author:	Streetz KL
Year:	2003
Journal:	Gastroenterology
Title:	Lack of gp130 expression in hepatocytes promotes liver injury.
Volume:	125
Issue:	2
Pages:	532-43

•

Publication

12147685 | J:79290

First Author:	Matsui T
Year:	2002
Journal:	J Biol Chem
Title:	STAT3 down-regulates the expression of cyclin D during liver development.
Volume:	277
Issue:	39
Pages:	36167-73

•

Publication

12831858 | J:84736

First Author:	Tamura S
Year:	2003
Journal:	Neuroscience
Title:	Localization of oncostatin M receptor beta in adult and developing CNS.
Volume:	119
Issue:	4
Pages:	991-7

•

Publication

15349890 | J:94930

First Author:	Kamiya A
Year:	2004
Journal:	Hepatology
Title:	TNF-alpha regulates mouse fetal hepatic maturation induced by oncostatin M and extracellular matrices.
Volume:	40
Issue:	3
Pages:	527-36

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Publication

15893881 | J:104249

First Author:	Tamura S
Year:	2005
Journal:	Neuroscience
Title:	Up-regulated phosphorylation of signal transducer and activator of transcription 3 and cyclic AMP-responsive element binding protein by peripheral inflammation in primary afferent neurons possibly through oncostatin M receptor.
Volume:	133
Issue:	3
Pages:	797-806

•

Publication

16291739 | J:110314

First Author:	Dekanty A
Year:	2006
Journal:	J Biol Chem
Title:	Leukemia inhibitory factor induces DNA synthesis in Swiss mouse 3T3 cells independently of cyclin D1 expression through a mechanism involving MEK/ERK1/2 activation.
Volume:	281
Issue:	10
Pages:	6136-43

•

Publication

11867530 | J:115358

First Author:	Matsui T
Year:	2002
Journal:	EMBO J
Title:	K-Ras mediates cytokine-induced formation of E-cadherin-based adherens junctions during liver development.
Volume:	21
Issue:	5
Pages:	1021-30

•

Publication

17214902 | J:119912

First Author:	Fong B
Year:	2007
Journal:	BMC Dev Biol
Title:	Mouse preimplantation embryo responses to culture medium osmolarity include increased expression of CCM2 and p38 MAPK activation.
Volume:	7

Pages:	2

•

Publication

21457934 | J:171268

First Author:	Hoermann G
Year:	2011
Journal:	Am J Pathol
Title:	Identification of oncostatin M as a STAT5-dependent mediator of bone marrow remodeling in KIT D816V-positive systemic mastocytosis.
Volume:	178
Issue:	5
Pages:	2344-56

•

Publication

21712438 | J:174387

First Author:	Zhou X
Year:	2011
Journal:	Proc Natl Acad Sci U S A
Title:	Rac1/osmosensing scaffold for MEKK3 contributes via phospholipase C-gamma1 to activation of the osmoprotective transcription factor NFAT5.
Volume:	108
Issue:	29
Pages:	12155-60

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Publication

22051730 | J:180613

First Author:	Hoermann G
Year:	2012
Journal:	FASEB J
Title:	Identification of oncostatin M as a JAK2 V617F-dependent amplifier of cytokine production and bone marrow remodeling in myeloproliferative neoplasms.
Volume:	26
Issue:	2
Pages:	894-906

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Publication

34408010 | J:322337

First Author:	Fraszczak J
Year:	2021
Journal:	J Immunol
Title:	Severe Inflammatory Reactions in Mice Expressing a GFI1^P2A Mutant Defective in Binding to the Histone Demethylase KDM1A (LSD1).
Volume:	207
Issue:	6
Pages:	1599-1615

•

Publication

34518644 | J:319704

First Author:	Bisht K
Year:	2022
Journal:	Leukemia
Title:	Oncostatin M regulates hematopoietic stem cell (HSC) niches in the bone marrow to restrict HSC mobilization.
Volume:	36
Issue:	2
Pages:	333-347

•

Publication

34757808 | J:344047

First Author:	Tseng PY
Year:	2021
Journal:	Sci Transl Med
Title:	Oncostatin M can sensitize sensory neurons in inflammatory pruritus.
Volume:	13
Issue:	619
Pages:	eabe3037

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Protein Coding Gene

MGI:96788 | Lifr

Type:	protein_coding_gene
Organism:	mouse, laboratory

•

Protein

Q8VE70

Organism:	Mus musculus/domesticus
Length:	212
Fragment?:	false

•

Protein

Q3TVB4

Organism:	Mus musculus/domesticus
Length:	162
Fragment?:	true

•

Protein

E0CY82

Organism:	Mus musculus/domesticus
Length:	66
Fragment?:	true

•

Publication

24595293 | J:208651

First Author:	Louvi A
Year:	2014
Journal:	Development
Title:	Ccm3, a gene associated with cerebral cavernous malformations, is required for neuronal migration.
Volume:	141
Issue:	6
Pages:	1404-15

•

Publication

24481819 | -

First Author:	Draheim KM
Year:	2014
Journal:	J Cell Sci
Title:	Cerebral cavernous malformation proteins at a glance.
Volume:	127
Issue:	Pt 4
Pages:	701-7

•

Publication

26490252 | -

First Author:	Lambertz N
Year:	2015
Journal:	BMC Cancer
Title:	Downregulation of programmed cell death 10 is associated with tumor cell proliferation, hyperangiogenesis and peritumoral edema in human glioblastoma.
Volume:	15

Pages:	759

•

Publication

30273401 | J:266636

First Author:	van Keulen D
Year:	2018
Journal:	PLoS One
Title:	Inflammatory cytokine oncostatin M induces endothelial activation in macro- and microvascular endothelial cells and in APOE*3Leiden.CETP mice.
Volume:	13
Issue:	10
Pages:	e0204911

•

Publication

30582455 | J:290188

First Author:	Ikeda S
Year:	2019
Journal:	Circ Res
Title:	Hippo Deficiency Leads to Cardiac Dysfunction Accompanied by Cardiomyocyte Dedifferentiation During Pressure Overload.
Volume:	124
Issue:	2
Pages:	292-305

•

Publication

26311783 | J:226167

First Author:	Guo S
Year:	2015
Journal:	J Neurosci
Title:	Oncostatin M Confers Neuroprotection against Ischemic Stroke.
Volume:	35
Issue:	34
Pages:	12047-62

•

Publication

31680865 | J:332408

First Author:	Sims SG
Year:	2019
Journal:	Front Cell Neurosci
Title:	Janus Kinase 1 Is Required for Transcriptional Reprograming of Murine Astrocytes in Response to Endoplasmic Reticulum Stress.
Volume:	13

Pages:	446

•

Publication

22774981 | J:188290

First Author:	Upadhyay A
Year:	2012
Journal:	Clin Exp Immunol
Title:	K/B×N serum transfer arthritis is delayed and less severe in leukaemia inhibitory factor (LIF)-deficient mice.
Volume:	169
Issue:	2
Pages:	71-8

•

Publication

15848385 | J:98062

First Author:	Fouladi-Nashta AA
Year:	2005
Journal:	Dev Biol
Title:	Characterization of the uterine phenotype during the peri-implantation period for LIF-null, MF1 strain mice.
Volume:	281
Issue:	1
Pages:	1-21

•

Publication

37688912 | J:341236

First Author:	Wang Z
Year:	2023
Journal:	Int Immunopharmacol
Title:	Tuberous sclerosis complex 1 targeted depletion in macrophages promotes osteogenesis by modulating secretion of Oncostatin M in the inflammatory stage of bone healing.
Volume:	124
Issue:	Pt A
Pages:	110895

•

Publication

25432964 | J:227787

First Author:	Xiao J
Year:	2015
Journal:	Toxicol Sci
Title:	Cyclooxygenase-1 serves a vital hepato-protective function in chemically induced acute liver injury.
Volume:	143
Issue:	2
Pages:	430-40

•

Publication

17379091 | J:123111

First Author:	Broxmeyer HE
Year:	2007
Journal:	Exp Hematol
Title:	Regulation of myeloid progenitor cell proliferation/survival by IL-31 receptor and IL-31.
Volume:	35
Issue:	4 Suppl 1
Pages:	78-86

•

Protein Coding Gene

MGI:96560 | Il6st

Type:	protein_coding_gene
Organism:	mouse, laboratory

•

Publication

32019420 | J:314488

First Author:	Wang Z
Year:	2021
Journal:	Autophagy
Title:	Autophagy-based unconventional secretion of HMGB1 by keratinocytes plays a pivotal role in psoriatic skin inﬂammation.
Volume:	17
Issue:	2
Pages:	529-552

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Protein

O70458

Organism:	Mus musculus/domesticus
Length:	971
Fragment?:	false

•

Protein

B9EHD2

Organism:	Mus musculus/domesticus
Length:	972
Fragment?:	false

•

Protein

A0A0R4J268

Organism:	Mus musculus/domesticus
Length:	970
Fragment?:	false

•

Protein

G3X8V6

Organism:	Mus musculus/domesticus
Length:	971
Fragment?:	false

•

Protein

P42703

Organism:	Mus musculus/domesticus
Length:	1092
Fragment?:	false

•

Protein

Q3UKU5

Organism:	Mus musculus/domesticus
Length:	719
Fragment?:	false

•

Protein

Q3U234

Organism:	Mus musculus/domesticus
Length:	1092
Fragment?:	false

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Search results 201 to 258 out of 258 for Osm

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