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Search results 101 to 197 out of 197 for Mvp

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:1398967
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4826517
Age: embryonic day 14.5
Image: euxassay_004411_23
Specimen Label: euxassay_004411_23
Detected: true
Specimen Num: 23
•
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1398967
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4826517
Age: embryonic day 14.5
Image: euxassay_004411_24
Specimen Label: euxassay_004411_24
Detected: true
Specimen Num: 24
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1398967
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826517
Age: embryonic day 14.5
Image: euxassay_004411_05
Specimen Label: euxassay_004411_05
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1398967
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826517
Age: embryonic day 14.5
Image: euxassay_004411_06
Specimen Label: euxassay_004411_06
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1398967
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826517
Age: embryonic day 14.5
Image: euxassay_004411_16
Specimen Label: euxassay_004411_16
Detected: true
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1398967
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826517
Age: embryonic day 14.5
Image: euxassay_004411_17
Specimen Label: euxassay_004411_17
Detected: true
Specimen Num: 17
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1398967
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826517
Age: embryonic day 14.5
Image: euxassay_004411_18
Specimen Label: euxassay_004411_18
Detected: true
Specimen Num: 18
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1398967
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1789623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826517
Age: embryonic day 14.5
Image: euxassay_004411_12
Specimen Label: euxassay_004411_12
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1398967
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4826517
Age: embryonic day 14.5
Image: euxassay_004411_06
Specimen Label: euxassay_004411_06
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1398967
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4826517
Age: embryonic day 14.5
Image: euxassay_004411_07
Specimen Label: euxassay_004411_07
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1398967
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4826517
Age: embryonic day 14.5
Image: euxassay_004411_08
Specimen Label: euxassay_004411_08
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1398967
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4826517
Age: embryonic day 14.5
Image: euxassay_004411_09
Specimen Label: euxassay_004411_09
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1398967
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4826517
Age: embryonic day 14.5
Image: euxassay_004411_10
Specimen Label: euxassay_004411_10
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1398967
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4826517
Age: embryonic day 14.5
Image: euxassay_004411_11
Specimen Label: euxassay_004411_11
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1398967
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4826517
Age: embryonic day 14.5
Image: euxassay_004411_12
Specimen Label: euxassay_004411_12
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1398967
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4826517
Age: embryonic day 14.5
Image: euxassay_004411_13
Specimen Label: euxassay_004411_13
Detected: true
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1398967
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4826517
Age: embryonic day 14.5
Image: euxassay_004411_16
Specimen Label: euxassay_004411_16
Detected: true
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1398967
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4826517
Age: embryonic day 14.5
Image: euxassay_004411_17
Specimen Label: euxassay_004411_17
Detected: true
Specimen Num: 17
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1398967
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4826517
Age: embryonic day 14.5
Image: euxassay_004411_18
Specimen Label: euxassay_004411_18
Detected: true
Specimen Num: 18
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1398967
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4826517
Age: embryonic day 14.5
Image: euxassay_004411_19
Specimen Label: euxassay_004411_19
Detected: true
Specimen Num: 19
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1398967
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4826517
Age: embryonic day 14.5
Image: euxassay_004411_20
Specimen Label: euxassay_004411_20
Detected: true
Specimen Num: 20
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1398967
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4826517
Age: embryonic day 14.5
Image: euxassay_004411_21
Specimen Label: euxassay_004411_21
Detected: true
Specimen Num: 21
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1398967
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4826517
Age: embryonic day 14.5
Image: euxassay_004411_22
Specimen Label: euxassay_004411_22
Detected: true
Specimen Num: 22
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1398967
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4826517
Age: embryonic day 14.5
Image: euxassay_004411_23
Specimen Label: euxassay_004411_23
Detected: true
Specimen Num: 23
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1398967
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826517
Age: embryonic day 14.5
Image: euxassay_004411_08
Specimen Label: euxassay_004411_08
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1398967
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826517
Age: embryonic day 14.5
Image: euxassay_004411_09
Specimen Label: euxassay_004411_09
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1398967
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826517
Age: embryonic day 14.5
Image: euxassay_004411_10
Specimen Label: euxassay_004411_10
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1398967
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826517
Age: embryonic day 14.5
Image: euxassay_004411_11
Specimen Label: euxassay_004411_11
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1398967
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826517
Age: embryonic day 14.5
Image: euxassay_004411_12
Specimen Label: euxassay_004411_12
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1398967
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826517
Age: embryonic day 14.5
Image: euxassay_004411_13
Specimen Label: euxassay_004411_13
Detected: true
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1398967
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826517
Age: embryonic day 14.5
Image: euxassay_004411_14
Specimen Label: euxassay_004411_14
Detected: true
Specimen Num: 14
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1398967
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826517
Age: embryonic day 14.5
Image: euxassay_004411_15
Specimen Label: euxassay_004411_15
Detected: true
Specimen Num: 15
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1398967
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826517
Age: embryonic day 14.5
Image: euxassay_004411_16
Specimen Label: euxassay_004411_16
Detected: true
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1398967
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826517
Age: embryonic day 14.5
Image: euxassay_004411_17
Specimen Label: euxassay_004411_17
Detected: true
Specimen Num: 17
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1398967
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826517
Age: embryonic day 14.5
Image: euxassay_004411_18
Specimen Label: euxassay_004411_18
Detected: true
Specimen Num: 18
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1398967
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826517
Age: embryonic day 14.5
Image: euxassay_004411_19
Specimen Label: euxassay_004411_19
Detected: true
Specimen Num: 19
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1398967
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826517
Age: embryonic day 14.5
Image: euxassay_004411_20
Specimen Label: euxassay_004411_20
Detected: true
Specimen Num: 20
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1398967
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826517
Age: embryonic day 14.5
Image: euxassay_004411_21
Specimen Label: euxassay_004411_21
Detected: true
Specimen Num: 21
•
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•
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Publication
- | J:73401
   
First Author: Strausberg R
Year: 2001
Journal: GenBank Submission
Title: Mus musculus, clone MGC:7951 IMAGE:3584439, mRNA, complete cds
Pages: BC006709
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Publication
11149928 | J:340412
First Author: Kickhoefer VA
Year: 2001
Journal: J Cell Biol
Title: The Telomerase/vault-associated protein TEP1 is required for vault RNA stability and its association with the vault particle.
Volume: 152
Issue: 1
Pages: 157-64
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•
Publication
34174788 | J:307968
First Author: He Y
Year: 2021
Journal: Aging Cell
Title: Single-cell RNA-Seq reveals a highly coordinated transcriptional program in mouse germ cells during primordial follicle formation.
Volume: 20
Issue: 7
Pages: e13424
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:68100
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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•
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
20555386 | -
First Author: Liang P
Year: 2010
Journal: Biochem Cell Biol
Title: MVP interacts with YPEL4 and inhibits YPEL4-mediated activities of the ERK signal pathway.
Volume: 88
Issue: 3
Pages: 445-50
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Protein
P63082
Organism: Mus musculus/domesticus
Length: 155  
Fragment?: false
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Allele
Mvp<tm1.1Smoc> | MGI:6885542
Name: major vault protein; targeted mutation 1.1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Conditional ready
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Publication
16918321 | -
First Author: Steiner E
Year: 2006
Journal: Curr Drug Targets
Title: Cellular functions of vaults and their involvement in multidrug resistance.
Volume: 7
Issue: 8
Pages: 923-34
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Protein Domain
IPR002499 | Vault_N
Type: Repeat
Description: Vaults are the largest ribonucleoprotein particles known, having a mass of approximately 13 MDa. They are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction and may also play a role in nucleo-cytoplasmic transport. Vaults are present in most normal tissues, but are more highly expressed in epithelial cells with secretory and excretory functions, as well as in cells chronically exposed to xenobiotics, such as bronchial cells and cells lining the intestine []. Overexpression of these proteins is linked with multidrug-resistance in cancer cells.The mammalian vault structure is highly regular and consists of approximately 96 molecules of the 100kDa major vault protein (MVP), 2 molecules of the 240kDa minor vault protein TEP1, 8 molecules of the 193kDa minor vault protein VPARP and at least 6 copies of a small untranslated RNA of 88-141 bases. The MVP molecules form the core of the complex, which is a barrel-like structure with an invaginated waist and two protruding caps. The complex can unfold into two symmetrical flower-like structures with 8 petals each supposedly consisting of 6 MVP molecules []. The MVP protein is composed of two distinct domains []. The N-terminal domain contains ~8 copies of the vault repeat (or MVP repeat) in tandem. The MVP repeat is composed of ~53 amino acids and forms a structural part of the vault wall. The C-terminal part of MVP may be involved in oligomerization and be located in the vault cap, while the MVP repeats in the N-terminal partcan be packed like staves in a barrel to form the vault wall. The 3D structure of the repeat forms a fold that consists of a three stranded (B) antiparallel β-sheet in a unique topology B2-B1-B3 and two loops. MVP repeats can be interaction-mediating modules, as MVP repeats 3 and 4 bind VPARP, which is one of the other vault proteins.
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Publication
16373071 | -
First Author: Kozlov G
Year: 2006
Journal: J Mol Biol
Title: Solution structure of a two-repeat fragment of major vault protein.
Volume: 356
Issue: 2
Pages: 444-52
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Publication
10196123 | -
First Author: Kong LB
Year: 1999
Journal: Structure
Title: Structure of the vault, a ubiquitous celular component.
Volume: 7
Issue: 4
Pages: 371-9
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Publication
19779459 | -
First Author: Querol-Audí J
Year: 2009
Journal: EMBO J
Title: The mechanism of vault opening from the high resolution structure of the N-terminal repeats of MVP.
Volume: 28
Issue: 21
Pages: 3450-7
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Protein Domain
IPR043023 | MVP_rep_sf
Type: Homologous_superfamily
Description: This superfamily represents a repeated domain found in the amino terminal half of the Major Vault Protein (MVP). Vaults are one of the largest cytoplasmic ribonucleoprotein particles, found in numerous eukaryotic species. The cellular function carried out by these ribonucleoproteins remains unclear, although roles in multidrug resistance and innate immunity have been suggested []. The primary sequence of MVP consists of seven short sequence repeats of ~55 amino acid residues followed by a central region and a coiled-coil protein association domain, which mediates the interactions between MVP molecules [].
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Protein Domain
IPR043179 | Vault_2_sf
Type: Homologous_superfamily
Description: The vault complex is the largest ribonucleoprotein particle found in eukaryotes []. Although several functions have been proposed for vaults since their discovery in 1986, including roles in multidrug resistance, cell signaling, and innate immunity, their cellular function remains unclear []. In mammals, vaults contain three proteins: the 100kDa major vault protein (MVP), the 193kDa vault poly(ADP-ribosyl)ating polymerase VPARP and the 240kDa telomerase-associated protein TEP1. Approximately 75% of the vault particle mass is due to MVP []. The MVP monomer folds to form structural repeat domains at the N terminus, a shoulder domain, a cap-helix and cap-ring domains.Thissuperfamily represents the major vault protein repeat domain 2, found at the N terminus.
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Publication
19150846 | -
First Author: Tanaka H
Year: 2009
Journal: Science
Title: The structure of rat liver vault at 3.5 angstrom resolution.
Volume: 323
Issue: 5912
Pages: 384-8
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Publication
32151560 | J:290862
First Author: Fulmer D
Year: 2020
Journal: Dev Biol
Title: Desert hedgehog-primary cilia cross talk shapes mitral valve tissue by organizing smooth muscle actin.
Volume: 463
Issue: 1
Pages: 26-38
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Publication
35200715 | J:327314
 
First Author: Moore KS
Year: 2022
Journal: J Cardiovasc Dev Dis
Title: DCHS1, Lix1L, and the Septin Cytoskeleton: Molecular and Developmental Etiology of Mitral Valve Prolapse.
Volume: 9
Issue: 2
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Publication
31118289 | J:291454
 
First Author: Toomer KA
Year: 2019
Journal: Sci Transl Med
Title: Primary cilia defects causing mitral valve prolapse.
Volume: 11
Issue: 493
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Publication
26258302 | J:225789
First Author: Durst R
Year: 2015
Journal: Nature
Title: Mutations in DCHS1 cause mitral valve prolapse.
Volume: 525
Issue: 7567
Pages: 109-13
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Publication
33811421 | J:311537
First Author: Guo L
Year: 2021
Journal: Dev Dyn
Title: DZIP1 regulates mammalian cardiac valve development through a Cby1-β-catenin mechanism.
Volume: 250
Issue: 10
Pages: 1432-1449
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Publication
15546004 | J:94428
First Author: Ng CM
Year: 2004
Journal: J Clin Invest
Title: TGF-beta-dependent pathogenesis of mitral valve prolapse in a mouse model of Marfan syndrome.
Volume: 114
Issue: 11
Pages: 1586-92
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Publication
37202505 | J:337540
First Author: Maier CR
Year: 2023
Journal: Cell Death Differ
Title: USP28 controls SREBP2 and the mevalonate pathway to drive tumour growth in squamous cancer.
Volume: 30
Issue: 7
Pages: 1710-1725
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Publication
26301497 | J:231945
First Author: Dina C
Year: 2015
Journal: Nat Genet
Title: Genetic association analyses highlight biological pathways underlying mitral valve prolapse.
Volume: 47
Issue: 10
Pages: 1206-11
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Publication
31399545 | J:278719
First Author: Hashimoto S
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: ARF6 and AMAP1 are major targets of KRAS and TP53 mutations to promote invasion, PD-L1 dynamics, and immune evasion of pancreatic cancer.
Volume: 116
Issue: 35
Pages: 17450-17459
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Publication
31112420 | J:320845
First Author: Yu M
Year: 2019
Journal: Circ Genom Precis Med
Title: Genome-Wide Association Study-Driven Gene-Set Analyses, Genetic, and Functional Follow-Up Suggest GLIS1 as a Susceptibility Gene for Mitral Valve Prolapse.
Volume: 12
Issue: 5
Pages: e002497
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Publication
32824919 | J:299128
 
First Author: Dye BK
Year: 2020
Journal: J Cardiovasc Dev Dis
Title: Smooth Muscle α-Actin Expression in Mitral Valve Interstitial Cells is Important for Mediating Extracellular Matrix Remodeling.
Volume: 7
Issue: 3
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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