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Search results 401 to 500 out of 646 for Fbn1

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Type Details Score
GXD Expression
GXD Expression
     
Probe: MGI:6479038
Assay Type: Immunohistochemistry
Annotation Date: 2020-12-14
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1783728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6479137
Age: postnatal day 24
Specimen Label: 4 Adamts10+/+ 24 days
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6479038
Assay Type: Immunohistochemistry
Annotation Date: 2020-12-14
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1783728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6479137
Age: postnatal day 8
Note: No change was noted in staining compared with wild type.
Specimen Label: 4 Adamts10-/- 8 days
Specimen Num: 2
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•
GXD Expression
GXD Expression
   
Probe: MGI:6479038
Assay Type: Immunohistochemistry
Annotation Date: 2020-12-14
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1783728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6479137
Age: postnatal day 24
Note: No change was noted in staining compared with wild type.
Specimen Label: 4 Adamts10-/- 24 days
Specimen Num: 4
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•
GXD Expression
GXD Expression
Probe: MGI:25888
Assay Type: RNA in situ
Annotation Date: 2019-06-19
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1701521
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6314411
Age: embryonic day 13.5
Image: 11B/D
Note: Expression was detected in the intimal and medial cells.
Specimen Label: 11B/D
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
Probe: MGI:25888
Assay Type: RNA in situ
Annotation Date: 2019-06-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3567624
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6314411
Age: embryonic day 16.5
Image: 6E/G
Note: Expression was detected in the perichondrium of the laryngeal cartilages.
Specimen Label: 6E/G
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:25888
Assay Type: RNA in situ
Annotation Date: 2019-06-19
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3567621
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6314411
Age: embryonic day 13.5
Image: 7E
Note: Expression was detected in the perichondrium of the long bones.
Specimen Label: 7E
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:25888
Assay Type: RNA in situ
Annotation Date: 2019-06-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3567624
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6314411
Age: embryonic day 16.5
Image: 7H
Note: Expression was detected in the perichondrium of the long bones.
Specimen Label: 7H
Detected: true
Specimen Num: 9
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•
GXD Expression
GXD Expression
Probe: MGI:25888
Assay Type: RNA in situ
Annotation Date: 2019-06-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3567624
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6314411
Age: embryonic day 16.5
Image: 7K
Note: Expression was detected in the perichondrium of flat bones.
Specimen Label: 7K
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
Probe: MGI:3053401
Assay Type: Immunohistochemistry
Annotation Date: 2022-02-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3567620
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6874605
Age: embryonic day 12.5
Image: 8E
Note: Expression was detected as short fibrillar deposits in the perichondrium of wild type embryos.
Specimen Label: 8E
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6258375
Assay Type: RNA in situ
Annotation Date: 2018-11-28
Strength: Absent
Sex: Female
Emaps: EMAPS:2991528
Stage: TS28
Assay Id: MGI:6258376
Age: postnatal adult
Specimen Label: not shown
Detected: false
Specimen Num: 6
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•
•
•
GXD Expression
GXD Expression
Probe: MGI:25888
Assay Type: RNA in situ
Annotation Date: 2019-06-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3545624
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6314411
Age: embryonic day 16.5
Image: 8B/C
Note: Expression was detected in cells surrounding ligaments and tendons.
Specimen Label: 8B/C
Detected: true
Specimen Num: 11
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•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6258375
Assay Type: RNA in situ
Annotation Date: 2018-11-28
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6258376
Age: embryonic day 13.5
Image: 4 day 13.5
Specimen Label: 4 day 13.5
Detected: false
Specimen Num: 3
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•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6258375
Assay Type: RNA in situ
Annotation Date: 2018-11-28
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:6258376
Age: embryonic day 16.5
Image: 4 day 16.5
Specimen Label: 4 day 16.5
Detected: false
Specimen Num: 4
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:25888
Assay Type: RNA in situ
Annotation Date: 2019-06-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609816
Pattern: Not Specified
Stage: TS16
Assay Id: MGI:6314411
Age: embryonic day 10.5
Image: 3B
Specimen Label: 3B
Detected: true
Specimen Num: 1
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•
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•
GXD Expression
GXD Expression
   
Probe: MGI:4846047
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2894521
Stage: TS21
Assay Id: MGI:5540858
Age: embryonic day 13.5
Image: GUDMAP:10908
Specimen Label: GUDMAP:10908
Detected: false
Specimen Num: 4
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:25888
Assay Type: RNA in situ
Annotation Date: 2019-06-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3514624
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6314411
Age: embryonic day 16.5
Image: 4J/L
Specimen Label: 4J/L
Detected: true
Specimen Num: 4
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•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4846047
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1796221
Stage: TS21
Assay Id: MGI:5540858
Age: embryonic day 13.5
Image: GUDMAP:10908
Specimen Label: GUDMAP:10908
Detected: false
Specimen Num: 4
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•
•
GXD Expression
GXD Expression
   
Probe: MGI:4423421
Assay Type: RNA in situ
Annotation Date: 2023-09-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1768022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7525193
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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•
•
GXD Expression
GXD Expression
   
Probe: MGI:4846047
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:3046021
Stage: TS21
Assay Id: MGI:5540858
Age: embryonic day 13.5
Image: GUDMAP:10905
Specimen Label: GUDMAP:10905
Detected: false
Specimen Num: 1
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•
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•
GXD Expression
GXD Expression
 
Probe: MGI:25888
Assay Type: RNA in situ
Annotation Date: 2019-06-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1761817
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6314411
Age: embryonic day 10.5
Image: 10C/D
Specimen Label: 10C/D
Detected: true
Specimen Num: 13
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:25888
Assay Type: RNA in situ
Annotation Date: 2019-06-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3549324
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6314411
Age: embryonic day 16.5
Image: 8B/C
Specimen Label: 8B/C
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6258375
Assay Type: RNA in situ
Annotation Date: 2018-11-28
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3274821
Stage: TS21
Assay Id: MGI:6258376
Age: embryonic day 13.5
Image: 4 day 13.5
Specimen Label: 4 day 13.5
Detected: false
Specimen Num: 3
•
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•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6258375
Assay Type: RNA in situ
Annotation Date: 2018-11-28
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3274824
Stage: TS24
Assay Id: MGI:6258376
Age: embryonic day 16.5
Image: 4 day 16.5
Specimen Label: 4 day 16.5
Detected: false
Specimen Num: 4
•
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•
GXD Expression
GXD Expression
     
Probe: MGI:6479038
Assay Type: Immunohistochemistry
Annotation Date: 2020-12-14
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3802928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6479137
Age: postnatal day 8
Specimen Label: 4 Adamts10+/+ 8 days
Specimen Num: 1
•
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•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6479038
Assay Type: Immunohistochemistry
Annotation Date: 2020-12-14
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3802928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6479137
Age: postnatal day 24
Specimen Label: 4 Adamts10+/+ 24 days
Specimen Num: 3
•
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•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6479038
Assay Type: Immunohistochemistry
Annotation Date: 2020-12-14
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3802928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6479137
Age: postnatal day 8
Note: No change was noted in staining compared with wild type.
Specimen Label: 4 Adamts10-/- 8 days
Specimen Num: 2
•
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•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6479038
Assay Type: Immunohistochemistry
Annotation Date: 2020-12-14
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3802928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6479137
Age: postnatal day 24
Note: No change was noted in staining compared with wild type.
Specimen Label: 4 Adamts10-/- 24 days
Specimen Num: 4
•
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•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6479038
Assay Type: Immunohistochemistry
Annotation Date: 2020-12-14
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3816928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6479134
Age: postnatal day 8
Specimen Label: 3C Adamts10+/+ 8 days
Specimen Num: 1
•
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•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6479038
Assay Type: Immunohistochemistry
Annotation Date: 2020-12-14
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3816928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6479134
Age: postnatal day 8
Specimen Label: 3C Adamts10-/- 8 days
Specimen Num: 2
•
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•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6479038
Assay Type: Immunohistochemistry
Annotation Date: 2020-12-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3816928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6479134
Age: postnatal week 6
Specimen Label: 3C Adamts10+/+ 6 weeks
Detected: true
Specimen Num: 3
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•
•
GXD Expression
GXD Expression
   
Probe: MGI:6479038
Assay Type: Immunohistochemistry
Annotation Date: 2020-12-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3816928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6479134
Age: postnatal year 1
Specimen Label: 3C Adamts10+/+ 1 year
Detected: true
Specimen Num: 5
•
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6479038
Assay Type: Immunohistochemistry
Annotation Date: 2020-12-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3816928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6479134
Age: postnatal year 1
Note: At 1 year of age, expression in the mutant zonule was comparable to wild type.
Specimen Label: 3C Adamts10-/- 1 year
Detected: true
Specimen Num: 6
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•
GXD Expression
GXD Expression
 
Probe: MGI:6479038
Assay Type: Immunohistochemistry
Annotation Date: 2020-12-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3816928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6479134
Age: postnatal week 6
Note: Expression was reduced in the 6 week zonule of the mutant.
Specimen Label: 3C Adamts10-/- 6 weeks
Detected: true
Specimen Num: 4
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•
GXD Expression
GXD Expression
 
Probe: MGI:7506509
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3816928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7506521
Age: postnatal month 6
Note: Microfibrils of the ciliary zonule were strongly labeled. Staining overlapped with the lens capsule in wild type.
Specimen Label: 3B WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7506509
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3816928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7506521
Age: postnatal month 6
Note: Microfibrils of the ciliary zonule were strongly labeled, as in wild type, but were discontinuous from the ciliary body to lens capsule.
Specimen Label: 3B tvrm267
Detected: true
Specimen Num: 2
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Publication
- | J:32746
   
First Author: Siracusa LD
Year: 1995
Journal: 9th International Mouse Genome Conference
Title: The molecular basis of the mouse tight skin (Tsk) mutation reveals its relationship to the microfibrillar protein, Fibrillin 1 (Fbn1)
Pages: 17 (Abstr. 5)
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Publication
30997682 | J:313846
First Author: Jung TW
Year: 2019
Journal: J Cell Physiol
Title: Asprosin attenuates insulin signaling pathway through PKCδ-activated ER stress and inflammation in skeletal muscle.
Volume: 234
Issue: 11
Pages: 20888-20899
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Publication
9642685 | J:48765
First Author: Phelps RG
Year: 1998
Journal: Mol Med
Title: Effect of targeted mutation in collagen V alpha 2 gene on development of cutaneous hyperplasia in tight skin mice.
Volume: 4
Issue: 5
Pages: 356-60
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Publication
7744963 | J:25216
First Author: Zhang H
Year: 1995
Journal: J Cell Biol
Title: Developmental expression of fibrillin genes suggests heterogeneity of extracellular microfibrils.
Volume: 129
Issue: 4
Pages: 1165-76
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Publication
28069701 | J:253368
First Author: Hulin A
Year: 2017
Journal: Cardiovasc Res
Title: Loss of Axin2 results in impaired heart valve maturation and subsequent myxomatous valve disease.
Volume: 113
Issue: 1
Pages: 40-51
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Publication
26408953 | J:237014
 
First Author: Smaldone S
Year: 2016
Journal: Matrix Biol
Title: Fibrillin microfibrils in bone physiology.
Volume: 52-54
Pages: 191-197
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Publication
21440062 | J:172294
First Author: Arteaga-Solis E
Year: 2011
Journal: Matrix Biol
Title: Material and mechanical properties of bones deficient for fibrillin-1 or fibrillin-2 microfibrils.
Volume: 30
Issue: 3
Pages: 188-94
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Publication
29371244 | J:271934
First Author: Galatioto J
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: Cell Type-Specific Contributions of the Angiotensin II Type 1a Receptor to Aorta Homeostasis and Aneurysmal Disease-Brief Report.
Volume: 38
Issue: 3
Pages: 588-591
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Publication
26902431 | J:239423
 
First Author: Walji TA
Year: 2016
Journal: Matrix Biol
Title: Characterization of metabolic health in mouse models of fibrillin-1 perturbation.
Volume: 55
Pages: 63-76
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Publication
29625025 | J:269186
First Author: Guo DC
Year: 2018
Journal: Am J Hum Genet
Title: LTBP3 Pathogenic Variants Predispose Individuals to Thoracic Aortic Aneurysms and Dissections.
Volume: 102
Issue: 4
Pages: 706-712
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Publication
21730037 | J:191706
First Author: Ferruzzi J
Year: 2011
Journal: Cardiovasc Res
Title: Mechanical assessment of elastin integrity in fibrillin-1-deficient carotid arteries: implications for Marfan syndrome.
Volume: 92
Issue: 2
Pages: 287-95
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Publication
26494287 | J:227267
First Author: Zilberberg L
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Genetic analysis of the contribution of LTBP-3 to thoracic aneurysm in Marfan syndrome.
Volume: 112
Issue: 45
Pages: 14012-7
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Publication
22550139 | J:212659
First Author: Xiong W
Year: 2012
Journal: Circ Res
Title: MMP-2 regulates Erk1/2 phosphorylation and aortic dilatation in Marfan syndrome.
Volume: 110
Issue: 12
Pages: e92-e101
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Publication
32616814 | J:294048
First Author: Jespersen K
Year: 2020
Journal: Sci Rep
Title: Enhanced Notch3 signaling contributes to pulmonary emphysema in a Murine Model of Marfan syndrome.
Volume: 10
Issue: 1
Pages: 10949
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Publication
30306291 | J:299123
First Author: Korneva A
Year: 2019
Journal: Biomech Model Mechanobiol
Title: Absence of LTBP-3 attenuates the aneurysmal phenotype but not spinal effects on the aorta in Marfan syndrome.
Volume: 18
Issue: 1
Pages: 261-273
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Publication
17237794 | J:117885
First Author: Cohn RD
Year: 2007
Journal: Nat Med
Title: Angiotensin II type 1 receptor blockade attenuates TGF-beta-induced failure of muscle regeneration in multiple myopathic states.
Volume: 13
Issue: 2
Pages: 204-10
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Publication
32578852 | J:309270
 
First Author: Xiao W
Year: 2020
Journal: Biosci Rep
Title: LncRNA Sox2ot modulates the progression of thoracic aortic aneurysm by regulating miR-330-5p/Myh11.
Volume: 40
Issue: 7
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Publication
26945079 | J:233008
First Author: Onetti Y
Year: 2016
Journal: Am J Physiol Heart Circ Physiol
Title: NADPH oxidase 4 attenuates cerebral artery changes during the progression of Marfan syndrome.
Volume: 310
Issue: 9
Pages: H1081-90
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Publication
30306735 | J:299047
First Author: Kim AJ
Year: 2019
Journal: Anat Rec (Hoboken)
Title: Endothelial Cell Lineage Analysis Does Not Provide Evidence for EMT in Adult Valve Homeostasis and Disease.
Volume: 302
Issue: 1
Pages: 125-135
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Publication
30004239 | J:266128
First Author: Parker SJ
Year: 2018
Journal: Am J Physiol Heart Circ Physiol
Title: Proteomics reveals Rictor as a noncanonical TGF-β signaling target during aneurysm progression in Marfan mice.
Volume: 315
Issue: 5
Pages: H1112-H1126
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Publication
26371162 | J:230673
First Author: Wisler JW
Year: 2015
Journal: Am J Physiol Heart Circ Physiol
Title: The role of β-arrestin2-dependent signaling in thoracic aortic aneurysm formation in a murine model of Marfan syndrome.
Volume: 309
Issue: 9
Pages: H1516-27
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Publication
23251680 | J:195662
First Author: Xu H
Year: 2012
Journal: PLoS One
Title: 4F decreases IRF5 expression and activation in hearts of tight skin mice.
Volume: 7
Issue: 12
Pages: e52046
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Publication
34407634 | J:321016
First Author: Chen JZ
Year: 2021
Journal: Arterioscler Thromb Vasc Biol
Title: Deletion of AT1a (Angiotensin II Type 1a) Receptor or Inhibition of Angiotensinogen Synthesis Attenuates Thoracic Aortopathies in Fibrillin1C1041G/+ Mice.
Volume: 41
Issue: 10
Pages: 2538-2550
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Publication
19850904 | J:167792
First Author: Carta L
Year: 2009
Journal: Arterioscler Thromb Vasc Biol
Title: Discrete contributions of elastic fiber components to arterial development and mechanical compliance.
Volume: 29
Issue: 12
Pages: 2083-9
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Publication
23104139 | J:319561
First Author: Hayes AJ
Year: 2013
Journal: Histochem Cell Biol
Title: Comparative immunolocalisation of fibrillin-1 and perlecan in the human foetal, and HS-deficient hspg2 exon 3 null mutant mouse intervertebral disc.
Volume: 139
Issue: 1
Pages: 1-11
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Publication
8791520 | J:42285
First Author: Ramirez F
Year: 1996
Journal: Curr Opin Genet Dev
Title: Fibrillln mutations in Marfan syndrome and related phenotypes.
Volume: 6
Issue: 3
Pages: 309-15
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Publication
15657057 | J:98020
First Author: Tiedemann K
Year: 2005
Journal: J Biol Chem
Title: Microfibrils at basement membrane zones interact with perlecan via fibrillin-1.
Volume: 280
Issue: 12
Pages: 11404-12
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Publication
15849235 | J:101242
First Author: Bouzeghrane F
Year: 2005
Journal: Am J Physiol Heart Circ Physiol
Title: Enhanced expression of fibrillin-1, a constituent of the myocardial extracellular matrix in fibrosis.
Volume: 289
Issue: 3
Pages: H982-91
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Publication
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