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Search results 1301 to 1400 out of 1421 for Tox

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Type Details Score
GXD Expression  
Probe: MGI:1990549
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828872
Age: embryonic day 14.5
Image: euxassay_006138_08
Specimen Label: euxassay_006138_08
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:1990549
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828872
Age: embryonic day 14.5
Image: euxassay_006138_09
Specimen Label: euxassay_006138_09
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:1990549
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828872
Age: embryonic day 14.5
Image: euxassay_006138_10
Specimen Label: euxassay_006138_10
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:1990549
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828872
Age: embryonic day 14.5
Image: euxassay_006138_11
Specimen Label: euxassay_006138_11
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:1990549
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828872
Age: embryonic day 14.5
Image: euxassay_006138_12
Specimen Label: euxassay_006138_12
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:1990549
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828872
Age: embryonic day 14.5
Image: euxassay_006138_13
Specimen Label: euxassay_006138_13
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:1990549
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828872
Age: embryonic day 14.5
Image: euxassay_006138_14
Specimen Label: euxassay_006138_14
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:1990549
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828872
Age: embryonic day 14.5
Image: euxassay_006138_15
Specimen Label: euxassay_006138_15
Detected: true
Specimen Num: 15
GXD Expression    
Probe: MGI:4845498
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1618415
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:4849010
Age: embryonic day 9.5
Specimen Label: Table S4 - E9.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4845498
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1618419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4849010
Age: embryonic day 11.5
Specimen Label: Table S4 - E11.5
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3506216
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5539251
Age: embryonic day 15.5
Image: GUDMAP:5533
Specimen Label: GUDMAP:5533
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3506218
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5539252
Age: embryonic day 15.5
Image: GUDMAP:5534
Specimen Label: GUDMAP:5534
Detected: false
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691795
Age: postnatal adult
Image: JAX_1632579
Specimen Label: JAX_1632579
Detected: true
Specimen Num: 22
GXD Expression    
Probe: MGI:6185679
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6189699
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - 5730589K01Rik
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6185679
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6189699
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - 5730589K01Rik
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6185679
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6189699
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - 5730589K01Rik
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6185679
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6189699
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - 5730589K01Rik
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6185679
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189699
Age: postnatal day 4
Specimen Label: Table S2 - P4 - 5730589K01Rik
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6185679
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189699
Age: postnatal day 14
Specimen Label: Table S2 - P14 - 5730589K01Rik
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6185679
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189699
Age: postnatal day 28
Specimen Label: Table S2 - P28 - 5730589K01Rik
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:6185677
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190728
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - LOC269389
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6185677
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190728
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - LOC269389
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6185677
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190728
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - LOC269389
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6185677
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190728
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - LOC269389
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6185677
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190728
Age: postnatal day 4
Specimen Label: Table S2 - P4 - LOC269389
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6185677
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190728
Age: postnatal day 14
Specimen Label: Table S2 - P14 - LOC269389
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6185677
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190728
Age: postnatal day 28
Specimen Label: Table S2 - P28 - LOC269389
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:6185678
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191494
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Tnrc9
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6185678
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191494
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Tnrc9
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6185678
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191494
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Tnrc9
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6185678
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191494
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Tnrc9
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6185678
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191494
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Tnrc9
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6185678
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191494
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Tnrc9
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6185678
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191494
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Tnrc9
Detected: true
Specimen Num: 7
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691795
Age: postnatal adult
Image: JAX_1632584
Specimen Label: JAX_1632584
Detected: true
Specimen Num: 27
GXD Expression  
Probe: MGI:3506216
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1796223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539251
Age: embryonic day 15.5
Image: GUDMAP:5533
Specimen Label: GUDMAP:5533
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691795
Age: postnatal adult
Image: JAX_1632582
Specimen Label: JAX_1632582
Detected: true
Specimen Num: 25
GXD Expression  
Probe: MGI:4845498
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1638817
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:4849010
Age: embryonic day 10.5
Note: Staining is present in the maxillary process.
Specimen Label: Table S4 - E10.5
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1881228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691795
Age: postnatal adult
Image: JAX_1632588
Specimen Label: JAX_1632588
Detected: true
Specimen Num: 31
GXD Expression  
Probe: MGI:1990549
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828872
Age: embryonic day 14.5
Image: euxassay_006138_09
Specimen Label: euxassay_006138_09
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:1990549
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828872
Age: embryonic day 14.5
Image: euxassay_006138_10
Specimen Label: euxassay_006138_10
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:1990549
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828872
Age: embryonic day 14.5
Image: euxassay_006138_11
Specimen Label: euxassay_006138_11
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:1990549
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828872
Age: embryonic day 14.5
Image: euxassay_006138_12
Specimen Label: euxassay_006138_12
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:6416490
Assay Type: RNA in situ
Annotation Date: 2020-05-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3671620
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6416497
Age: embryonic day 12.5
Note: Expressed in the ganglionic eminences.
Specimen Label: 3E
Detected: true
Specimen Num: 1
Allele
Name: thymocyte selection-associated high mobility group box; targeted mutation 2.1, Jonathan Kaye
Allele Type: Targeted
Attribute String: Reporter
Strain
Attribute String: mutant strain, coisogenic, targeted mutation
Strain
Attribute String: mutant strain, coisogenic, targeted mutation
Strain
Attribute String: mutant strain, coisogenic, targeted mutation
Strain
Attribute String: mutant strain, coisogenic, targeted mutation
Genotype
Symbol: Tox3/Tox3<+>
Background: C57BL/6NCrl-Tox3/Tcp
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Tox4/Tox4<+>
Background: C57BL/6N-Tox4/J
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Tox3/Tox3<+>
Background: C57BL/6N-Tox3/Ucd
Zygosity: ht
Has Mutant Allele: true
HT Experiment
Series Id: E-GEOD-65850
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
Publication
First Author: Huang Y
Year: 2024
Journal: Cell Death Dis
Title: E3 ligase TRIM65 alleviates intestinal ischemia/reperfusion injury through inhibition of TOX4-mediated apoptosis.
Volume: 15
Issue: 1
Pages: 29
Publication  
First Author: Liang S
Year: 2004
Journal: Mol Vis
Title: Novel retinal genes discovered by mining the mouse embryonic RetinalExpress database.
Volume: 10
Pages: 773-86
Publication
First Author: Sahu SK
Year: 2016
Journal: Biochim Biophys Acta
Title: TOX3 regulates neural progenitor identity.
Volume: 1859
Issue: 7
Pages: 833-40
Publication
First Author: Qiu X
Year: 1995
Journal: Structure
Title: Three-dimensional structure of the diphtheria toxin repressor in complex with divalent cation co-repressors.
Volume: 3
Issue: 1
Pages: 87-100
Publication
First Author: Bastien D
Year: 2015
Journal: J Neurosci
Title: IL-1α Gene Deletion Protects Oligodendrocytes after Spinal Cord Injury through Upregulation of the Survival Factor Tox3.
Volume: 35
Issue: 30
Pages: 10715-30
Protein Domain
Type: Homologous_superfamily
Description: The diphtheria toxin repressor protein (DTXR) is a member of this group []. In Corynebacterium diphtheriae where it has been studied in some detail this protein acts as an iron-binding repressor of diphtheria toxin gene expression and may serve as a global regulator of gene expression. DTXR comprises an N-terminal DNA-binding domain, an interface domain (which contains two metal-binding sites) and a third, very flexible C-terminal domain. The second domain is responsible for dimerization and metal binding. The N terminus may be involved in iron binding and may associate with the Tox operator. Binding of DTXR to Tox operator requires a divalent metal ion such as cobalt, ferric, manganese and nickel whereas zinc shows weak activation [].The dimerisation domain is composed of six helices, each one containing a homodimer of 3-helical domains.
Protein Domain
Type: Family
Description: This entry represents a group of iron dependent repressors, including MntR, IdeR and diphtheria toxin repressor.The diphtheria toxin repressor protein (DTXR) is a member of this group []. In Corynebacterium diphtheriae where it has been studied in some detail this protein acts as an iron-binding repressor of diphtheria toxin gene expression and may serve as a global regulator of gene expression. DTXR comprises an N-terminal DNA-binding domain, an interface domain (which contains two metal-binding sites) and a third, very flexible C-terminal domain. The second domain is responsible for dimerization and metal binding. The N terminus may be involved in iron binding and may associate with the Tox operator. Binding of DTXR to Tox operator requires a divalent metal ion such as cobalt, ferric, manganese and nickel whereas zinc shows weak activation [].
Protein Domain
Type: Domain
Description: The diphtheria toxin repressor protein (DTXR) is a member of this group []. In Corynebacterium diphtheriae where it has been studied in some detail this protein acts as an iron-binding repressor of diphtheria toxin gene expression and may serve as a global regulator of gene expression. DTXR comprises an N-terminal DNA-binding domain, an interface domain (which contains two metal-binding sites) and a third, very flexible C-terminal domain. The second domain is responsible for dimerization and metal binding. The N terminus may be involved in iron binding and may associate with the Tox operator. Binding of DTXR to Tox operator requires a divalent metal ion such as cobalt, ferric, manganese and nickel whereas zinc shows weak activation [].
Genotype
Symbol: Tg(Tox)1Kay/? Tox/Tox
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Publication
First Author: Wise TL
Year: 2004
Journal: Genetics
Title: Oligosyndactylism mice have an inversion of chromosome 8.
Volume: 168
Issue: 4
Pages: 2099-112
Publication
First Author: Spieler D
Year: 2014
Journal: Genome Res
Title: Restless legs syndrome-associated intronic common variant in Meis1 alters enhancer function in the developing telencephalon.
Volume: 24
Issue: 4
Pages: 592-603
Publication
First Author: Cao J
Year: 2019
Journal: Nature
Title: The single-cell transcriptional landscape of mammalian organogenesis.
Volume: 566
Issue: 7745
Pages: 496-502
Publication
First Author: Zhu Q
Year: 2023
Journal: Dev Cell
Title: Decoding anterior-posterior axis emergence among mouse, monkey, and human embryos.
Volume: 58
Issue: 1
Pages: 63-79.e4
Allele
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2.1, Patricia Jensen
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
Publication  
First Author: Lewis EL
Year: 2022
Journal: J Exp Med
Title: NFAT-dependent and -independent exhaustion circuits program maternal CD8 T cell hypofunction in pregnancy.
Volume: 219
Issue: 1
Publication
First Author: Wu CJ
Year: 2019
Journal: Sci Adv
Title: MiR-23~27~24-mediated control of humoral immunity reveals a TOX-driven regulatory circuit in follicular helper T cell differentiation.
Volume: 5
Issue: 12
Pages: eaaw1715
Publication
First Author: Li H
Year: 2019
Journal: Mol Psychiatry
Title: Disruption of TCF4 regulatory networks leads to abnormal cortical development and mental disabilities.
Volume: 24
Issue: 8
Pages: 1235-1246
Strain
Attribute String: mutant strain, congenic, targeted mutation
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor
Background: B6.Cg-Gt(ROSA)26Sor/J
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Bohuslavova R
Year: 2023
Journal: Nat Commun
Title: NEUROD1 reinforces endocrine cell fate acquisition in pancreatic development.
Volume: 14
Issue: 1
Pages: 5554
Publication
First Author: Burrack AL
Year: 2021
Journal: J Immunol
Title: CD40 Agonist Overcomes T Cell Exhaustion Induced by Chronic Myeloid Cell IL-27 Production in a Pancreatic Cancer Preclinical Model.
Volume: 206
Issue: 6
Pages: 1372-1384
Publication
First Author: O'Connell P
Year: 2021
Journal: J Immunol
Title: SLAMF7 Signaling Reprograms T Cells toward Exhaustion in the Tumor Microenvironment.
Volume: 206
Issue: 1
Pages: 193-205
Publication
First Author: Upham J
Year: 2007
Journal: Biochim Biophys Acta
Title: The pesticide adjuvant, Toximul, alters hepatic metabolism through effects on downstream targets of PPARalpha.
Volume: 1772
Issue: 9
Pages: 1057-64
Publication
First Author: Tucker CG
Year: 2020
Journal: J Immunol
Title: Adoptive T Cell Therapy with IL-12-Preconditioned Low-Avidity T Cells Prevents Exhaustion and Results in Enhanced T Cell Activation, Enhanced Tumor Clearance, and Decreased Risk for Autoimmunity.
Volume: 205
Issue: 5
Pages: 1449-1460
Publication
First Author: Page N
Year: 2021
Journal: Nat Commun
Title: Persistence of self-reactive CD8+ T cells in the CNS requires TOX-dependent chromatin remodeling.
Volume: 12
Issue: 1
Pages: 1009
Publication
First Author: Maestre L
Year: 2020
Journal: PLoS One
Title: High-mobility group box (TOX) antibody a useful tool for the identification of B and T cell subpopulations.
Volume: 15
Issue: 2
Pages: e0229743
Publication
First Author: Paul A
Year: 2017
Journal: Cell
Title: Transcriptional Architecture of Synaptic Communication Delineates GABAergic Neuron Identity.
Volume: 171
Issue: 3
Pages: 522-539.e20
Publication
First Author: Klein AD
Year: 2016
Journal: Cell Rep
Title: Identification of Modifier Genes in a Mouse Model of Gaucher Disease.
Volume: 16
Issue: 10
Pages: 2546-2553
Publication      
First Author: The Mammalian Genetics Unit at Harwell
Year: 2004
Journal: Unpublished
Title: Information obtained from the Mammalian Genetics Unit, Medical Research Council (MRC), Harwell, UK
Publication
First Author: Sima J
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation.
Volume: 115
Issue: 32
Pages: 8173-8178
Publication
First Author: Scavuzzo MA
Year: 2018
Journal: Nat Commun
Title: Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis.
Volume: 9
Issue: 1
Pages: 3356
Publication      
First Author: Moffat A
Year: 2024
Journal: bioRxiv
Title: Proneural genes form a combinatorial code to diversify neocortical neural progenitor cells.
Publication
First Author: Ravasi T
Year: 2010
Journal: Cell
Title: An atlas of combinatorial transcriptional regulation in mouse and man.
Volume: 140
Issue: 5
Pages: 744-52
Publication      
First Author: Centre for Modeling Human Disease
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the NorCOMM project by the Centre for Modeling Human Disease (Cmhd), Institute of Biomaterials & Biomedical Engineering, University of Toronto
Publication
First Author: Han S
Year: 2021
Journal: Neuron
Title: Proneural genes define ground-state rules to regulate neurogenic patterning and cortical folding.
Volume: 109
Issue: 18
Pages: 2847-2863.e11
Publication
First Author: Zhou Q
Year: 2007
Journal: Dev Cell
Title: A multipotent progenitor domain guides pancreatic organogenesis.
Volume: 13
Issue: 1
Pages: 103-14
Publication
First Author: Bulfone A
Year: 2005
Journal: J Neurosci
Title: Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes.
Volume: 25
Issue: 33
Pages: 7586-600
Publication
First Author: Okazaki N
Year: 2004
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 11
Issue: 3
Pages: 205-18
Publication      
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
Publication      
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
Publication
First Author: Guo A
Year: 2014
Journal: Mol Cell Proteomics
Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.
Volume: 13
Issue: 1
Pages: 372-87
Publication      
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
Publication
First Author: Trost M
Year: 2009
Journal: Immunity
Title: The phagosomal proteome in interferon-gamma-activated macrophages.
Volume: 30
Issue: 1
Pages: 143-54
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
Publication        
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration