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Search results 101 to 200 out of 3062 for Sox10

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Type Details Score
Publication
First Author: John N
Year: 2011
Journal: Stem Cells
Title: Transforming growth factor β-mediated Sox10 suppression controls mesenchymal progenitor generation in neural crest stem cells.
Volume: 29
Issue: 4
Pages: 689-99
Heritable Phenotypic Marker
Type: heritable_phenotypic_marker
Organism: mouse, laboratory
Publication
First Author: Deal KK
Year: 2006
Journal: Dev Dyn
Title: Distant regulatory elements in a Sox10-beta GEO BAC transgene are required for expression of Sox10 in the enteric nervous system and other neural crest-derived tissues.
Volume: 235
Issue: 5
Pages: 1413-32
Protein
Organism: Mus musculus/domesticus
Length: 506  
Fragment?: true
Publication
First Author: Polanco JC
Year: 2010
Journal: Hum Mol Genet
Title: Sox10 gain-of-function causes XX sex reversal in mice: implications for human 22q-linked disorders of sex development.
Volume: 19
Issue: 3
Pages: 506-16
Publication
First Author: Breuskin I
Year: 2009
Journal: Dev Biol
Title: Sox10 promotes the survival of cochlear progenitors during the establishment of the organ of Corti.
Volume: 335
Issue: 2
Pages: 327-39
Publication
First Author: Finzsch M
Year: 2010
Journal: J Cell Biol
Title: Sox10 is required for Schwann cell identity and progression beyond the immature Schwann cell stage.
Volume: 189
Issue: 4
Pages: 701-12
Publication
First Author: Vogl MR
Year: 2013
Journal: J Neurosci
Title: Sox10 cooperates with the mediator subunit 12 during terminal differentiation of myelinating glia.
Volume: 33
Issue: 15
Pages: 6679-90
GXD Expression    
Probe: MGI:6159070
Assay Type: Immunohistochemistry
Annotation Date: 2022-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1611819
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:7332913
Age: embryonic day 11.5
Specimen Label: 1H Sox10 Control
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:6159070
Assay Type: Immunohistochemistry
Annotation Date: 2022-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1611819
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:7332913
Age: embryonic day 11.5
Note: Expression unaltered compared to control.
Specimen Label: 1H Sox10 Yy1 cko
Detected: true
Specimen Num: 4
Publication
First Author: Mao Y
Year: 2014
Journal: PLoS One
Title: Targeted deletion of Sox10 by Wnt1-cre defects neuronal migration and projection in the mouse inner ear.
Volume: 9
Issue: 4
Pages: e94580
Publication
First Author: Hodonsky CJ
Year: 2012
Journal: Mol Cell Neurosci
Title: SOX10 regulates expression of the SH3-domain kinase binding protein 1 (Sh3kbp1) locus in Schwann cells via an alternative promoter.
Volume: 49
Issue: 2
Pages: 85-96
Publication
First Author: Bernhardt C
Year: 2022
Journal: Nucleic Acids Res
Title: KLF9 and KLF13 transcription factors boost myelin gene expression in oligodendrocytes as partners of SOX10 and MYRF.
Volume: 50
Issue: 20
Pages: 11509-11528
Publication
First Author: Szeto IYY
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: SOX9 and SOX10 control fluid homeostasis in the inner ear for hearing through independent and cooperative mechanisms.
Volume: 119
Issue: 46
Pages: e2122121119
Publication
First Author: Harris ML
Year: 2013
Journal: PLoS Genet
Title: A dual role for SOX10 in the maintenance of the postnatal melanocyte lineage and the differentiation of melanocyte stem cell progenitors.
Volume: 9
Issue: 7
Pages: e1003644
Publication
First Author: Hou L
Year: 2004
Journal: Dev Dyn
Title: Complementation of melanocyte development in SOX10 mutant neural crest using lineage-directed gene transfer.
Volume: 229
Issue: 1
Pages: 54-62
GXD Expression  
Probe: MGI:6400500
Assay Type: RNA in situ
Annotation Date: 2020-03-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666517
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6400509
Age: embryonic day 10.5
Note: No difference in expression in peripheral nervous system component derived from neural crest between mutant and control embryos.
Specimen Label: Sox10 E10.5 wt/wt not shown
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6400500
Assay Type: RNA in situ
Annotation Date: 2020-03-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666517
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6400509
Age: embryonic day 10.5
Specimen Label: Sox10 E10.5 m1Will/m1Will not shown
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3519721
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7513009
Age: embryonic day 13.5
Image: 1A Sox10 lacZ/+ ce
Note: Trace or absent, presented with colonization delay.
Specimen Label: 1A Sox10 lacZ/+ ce
Specimen Num: 11
GXD Expression  
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3519722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7513009
Age: embryonic day 14.5
Image: 2A Sox10 lacZ/+ ce
Specimen Label: 2A Sox10 lacZ/+ ce
Detected: true
Specimen Num: 25
GXD Expression    
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3519720
Stage: TS20
Assay Id: MGI:7513009
Age: embryonic day 12.25
Image: 4B Sox10 beta1-null
Specimen Label: 4B Sox10 beta1-null
Detected: false
Specimen Num: 59
GXD Expression    
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3519720
Stage: TS20
Assay Id: MGI:7513009
Age: embryonic day 12.25
Image: 4B Sox10 lacZ/+
Specimen Label: 4B Sox10 lacZ/+
Detected: false
Specimen Num: 58
GXD Expression  
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1925221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7513009
Age: embryonic day 13.5
Image: 1A Sox10 lacZ/+ co
Note: Trace or absent in the colon, presented with colonization delay.
Specimen Label: 1A Sox10 lacZ/+ co
Specimen Num: 12
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1925222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7513009
Age: embryonic day 14.5
Image: 2A Sox10 lacZ/+ co
Note: Colonization delay was seen. No positive cells from the middle of the colon caudally.
Specimen Label: 2A Sox10 lacZ/+ co
Detected: true
Specimen Num: 26
GXD Expression    
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1925220
Stage: TS20
Assay Id: MGI:7513009
Age: embryonic day 12.25
Image: 4B Sox10 beta1-null
Specimen Label: 4B Sox10 beta1-null
Detected: false
Specimen Num: 59
GXD Expression    
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1925220
Stage: TS20
Assay Id: MGI:7513009
Age: embryonic day 12.25
Image: 4B Sox10 lacZ/+
Specimen Label: 4B Sox10 lacZ/+
Detected: false
Specimen Num: 58
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3642221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7513009
Age: embryonic day 13.5
Image: 1A Sox10 lacZ/+ s
Note: Fully colonized enteric neural crest cells, similar as in the wild-type.
Specimen Label: 1A Sox10 lacZ/+ s
Detected: true
Specimen Num: 9
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3642221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7513009
Age: embryonic day 13.5
Image: 1A Sox10 lacZ/+ si
Note: Fully colonized enteric neural crest cells, similar as in the wild-type.
Specimen Label: 1A Sox10 lacZ/+ si
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3642221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7513009
Age: embryonic day 13.5
Image: 1A Sox10 lacZ/+ ce
Note: Trace or absent, presented with colonization delay.
Specimen Label: 1A Sox10 lacZ/+ ce
Specimen Num: 11
GXD Expression  
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3642221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7513009
Age: embryonic day 13.5
Image: 1A Sox10 lacZ/+ co
Note: Trace or absent in the colon, presented with colonization delay.
Specimen Label: 1A Sox10 lacZ/+ co
Specimen Num: 12
GXD Expression  
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3642222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7513009
Age: embryonic day 14.5
Image: 2A Sox10 lacZ/+ s
Specimen Label: 2A Sox10 lacZ/+ s
Detected: true
Specimen Num: 22
GXD Expression  
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3642222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7513009
Age: embryonic day 14.5
Image: 2A Sox10 lacZ/+ si-p
Specimen Label: 2A Sox10 lacZ/+ si-p
Detected: true
Specimen Num: 23
GXD Expression  
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3642222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7513009
Age: embryonic day 14.5
Image: 2A Sox10 lacZ/+ si-m
Specimen Label: 2A Sox10 lacZ/+ si-m
Detected: true
Specimen Num: 24
GXD Expression  
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3642222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7513009
Age: embryonic day 14.5
Image: 2A Sox10 lacZ/+ ce
Specimen Label: 2A Sox10 lacZ/+ ce
Detected: true
Specimen Num: 25
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3642222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7513009
Age: embryonic day 14.5
Image: 2A Sox10 lacZ/+ co
Note: Colonization delay was seen. No positive cells from the middle of the colon caudally.
Specimen Label: 2A Sox10 lacZ/+ co
Detected: true
Specimen Num: 26
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3642222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7513009
Age: embryonic day 14.5
Image: 2C Sox10 lacZ/+
Note: Normal neuronal network as in the wild-type.
Specimen Label: 2C Sox10 lacZ/+
Detected: true
Specimen Num: 42
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3642220
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7513009
Age: embryonic day 12.25
Image: 4B Sox10 beta1-null
Note: Slight delay in colonization compared to controls, with the front of migrating enteric neural crest cells in the mutants stopping just before the caecum.
Specimen Label: 4B Sox10 beta1-null
Detected: true
Specimen Num: 59
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3642220
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7513009
Age: embryonic day 12.25
Image: 4B Sox10 lacZ/+
Note: Slight delay in colonization compared to controls, with the front of migrating enteric neural crest cells in the mutants stopping in the final quarter of the midgut.
Specimen Label: 4B Sox10 lacZ/+
Detected: true
Specimen Num: 58
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7513009
Age: embryonic day 13.5
Image: 1A Sox10 lacZ/+ si
Note: Fully colonized enteric neural crest cells, similar as in the wild-type.
Specimen Label: 1A Sox10 lacZ/+ si
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7513009
Age: embryonic day 14.5
Image: 2A Sox10 lacZ/+ si-p
Specimen Label: 2A Sox10 lacZ/+ si-p
Detected: true
Specimen Num: 23
GXD Expression  
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7513009
Age: embryonic day 14.5
Image: 2A Sox10 lacZ/+ si-m
Specimen Label: 2A Sox10 lacZ/+ si-m
Detected: true
Specimen Num: 24
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7513009
Age: embryonic day 14.5
Image: 2C Sox10 lacZ/+
Note: Normal neuronal network as in the wild-type.
Specimen Label: 2C Sox10 lacZ/+
Detected: true
Specimen Num: 42
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283420
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7513009
Age: embryonic day 12.25
Image: 4B Sox10 beta1-null
Note: Slight delay in colonization compared to controls, with the front of migrating enteric neural crest cells in the mutants stopping just before the caecum.
Specimen Label: 4B Sox10 beta1-null
Detected: true
Specimen Num: 59
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283420
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7513009
Age: embryonic day 12.25
Image: 4B Sox10 lacZ/+
Note: Slight delay in colonization compared to controls, with the front of migrating enteric neural crest cells in the mutants stopping in the final quarter of the midgut.
Specimen Label: 4B Sox10 lacZ/+
Detected: true
Specimen Num: 58
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283427
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7513009
Age: postnatal newborn
Image: 5A Sox10 lacZ/+
Note: The network was similar as in the controls.
Specimen Label: 5A Sox10 lacZ/+
Detected: true
Specimen Num: 63
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2692221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7513009
Age: embryonic day 13.5
Image: 1A Sox10 lacZ/+ s
Note: Fully colonized enteric neural crest cells, similar as in the wild-type.
Specimen Label: 1A Sox10 lacZ/+ s
Detected: true
Specimen Num: 9
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2692221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7513009
Age: embryonic day 13.5
Image: 1A Sox10 lacZ/+ si
Note: Fully colonized enteric neural crest cells, similar as in the wild-type.
Specimen Label: 1A Sox10 lacZ/+ si
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:2692221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7513009
Age: embryonic day 13.5
Image: 1A Sox10 lacZ/+ ce
Note: Trace or absent, presented with colonization delay.
Specimen Label: 1A Sox10 lacZ/+ ce
Specimen Num: 11
GXD Expression  
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:2692221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7513009
Age: embryonic day 13.5
Image: 1A Sox10 lacZ/+ co
Note: Trace or absent in the colon, presented with colonization delay.
Specimen Label: 1A Sox10 lacZ/+ co
Specimen Num: 12
GXD Expression  
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2692222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7513009
Age: embryonic day 14.5
Image: 2A Sox10 lacZ/+ s
Specimen Label: 2A Sox10 lacZ/+ s
Detected: true
Specimen Num: 22
GXD Expression  
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2692222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7513009
Age: embryonic day 14.5
Image: 2A Sox10 lacZ/+ si-p
Specimen Label: 2A Sox10 lacZ/+ si-p
Detected: true
Specimen Num: 23
GXD Expression  
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2692222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7513009
Age: embryonic day 14.5
Image: 2A Sox10 lacZ/+ si-m
Specimen Label: 2A Sox10 lacZ/+ si-m
Detected: true
Specimen Num: 24
GXD Expression  
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2692222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7513009
Age: embryonic day 14.5
Image: 2A Sox10 lacZ/+ ce
Specimen Label: 2A Sox10 lacZ/+ ce
Detected: true
Specimen Num: 25
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2692222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7513009
Age: embryonic day 14.5
Image: 2A Sox10 lacZ/+ co
Note: Colonization delay was seen. No positive cells from the middle of the colon caudally.
Specimen Label: 2A Sox10 lacZ/+ co
Detected: true
Specimen Num: 26
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2692222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7513009
Age: embryonic day 14.5
Image: 2C Sox10 lacZ/+
Note: Normal neuronal network as in the wild-type.
Specimen Label: 2C Sox10 lacZ/+
Detected: true
Specimen Num: 42
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2692220
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7513009
Age: embryonic day 12.25
Image: 4B Sox10 beta1-null
Note: Slight delay in colonization compared to controls, with the front of migrating enteric neural crest cells in the mutants stopping just before the caecum.
Specimen Label: 4B Sox10 beta1-null
Detected: true
Specimen Num: 59
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2692220
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7513009
Age: embryonic day 12.25
Image: 4B Sox10 lacZ/+
Note: Slight delay in colonization compared to controls, with the front of migrating enteric neural crest cells in the mutants stopping in the final quarter of the midgut.
Specimen Label: 4B Sox10 lacZ/+
Detected: true
Specimen Num: 58
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2692227
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7513009
Age: postnatal newborn
Image: 5A Sox10 lacZ/+
Note: The network was similar as in the controls.
Specimen Label: 5A Sox10 lacZ/+
Detected: true
Specimen Num: 63
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702121
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7513009
Age: embryonic day 13.5
Image: 1A Sox10 lacZ/+ s
Note: Fully colonized enteric neural crest cells, similar as in the wild-type.
Specimen Label: 1A Sox10 lacZ/+ s
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7513009
Age: embryonic day 14.5
Image: 2A Sox10 lacZ/+ s
Specimen Label: 2A Sox10 lacZ/+ s
Detected: true
Specimen Num: 22
GXD Expression  
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7513009
Age: embryonic day 12.25
Image: 4B Sox10 beta1-null
Specimen Label: 4B Sox10 beta1-null
Detected: true
Specimen Num: 59
GXD Expression  
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7513009
Age: embryonic day 12.25
Image: 4B Sox10 lacZ/+
Specimen Label: 4B Sox10 lacZ/+
Detected: true
Specimen Num: 58
Publication
First Author: Su Z
Year: 2020
Journal: J Cell Mol Med
Title: KIT ligand produced by limbal niche cells under control of SOX10 maintains limbal epithelial stem cell survival by activating the KIT/AKT signalling pathway.
Volume: 24
Issue: 20
Pages: 12020-12031
Publication
First Author: Paratore C
Year: 2001
Journal: Development
Title: Survival and glial fate acquisition of neural crest cells are regulated by an interplay between the transcription factor Sox10 and extrinsic combinatorial signaling.
Volume: 128
Issue: 20
Pages: 3949-61
Publication
First Author: Cossais F
Year: 2010
Journal: Dev Biol
Title: Replacement of mouse Sox10 by the Drosophila ortholog Sox100B provides evidence for co-option of SoxE proteins into vertebrate-specific gene-regulatory networks through altered expression.
Volume: 341
Issue: 1
Pages: 267-81
Publication
First Author: Watanabe Y
Year: 2017
Journal: Gastroenterology
Title: Differentiation of Mouse Enteric Nervous System Progenitor Cells Is Controlled by Endothelin 3 and Requires Regulation of Ednrb by SOX10 and ZEB2.
Volume: 152
Issue: 5
Pages: 1139-1150.e4
GXD Expression    
Probe: MGI:6184025
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191359
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Sox10
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6184025
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191359
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Sox10
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6184025
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191359
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Sox10
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6184025
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191359
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Sox10
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6184025
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191359
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Sox10
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6184025
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191359
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Sox10
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6184025
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191359
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Sox10
Detected: true
Specimen Num: 7
GXD Expression
Probe: MGI:3055733
Assay Type: RNA in situ
Annotation Date: 2004-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666816
Pattern: Single cells
Stage: TS16
Assay Id: MGI:3055734
Age: embryonic day 10.0
Image: 6.A
Note: Sox10 marks cell in the Dorsal Root Ganglion of Neural Crest origin.
Specimen Label: 6.A
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:7595611
Assay Type: RNA in situ
Annotation Date: 2024-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3273713
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:7595647
Age: embryonic day 8.5-9.0
Image: 6M
Note: Sox10 expression was analyzed as a marker of r2- and r4-derived neural crest cells.
Specimen Label: 6M
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:7595611
Assay Type: RNA in situ
Annotation Date: 2024-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3273713
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:7595647
Age: embryonic day 8.5-9.0
Image: 6N
Note: Sox10 expression was analyzed as a marker of r2- and r4-derived neural crest cells.
Specimen Label: 6N
Detected: true
Specimen Num: 2
Publication      
First Author: Smart NG
Year: 2008
Journal: MGI Direct Data Submission
Title: Dalmatian, a mouse white spotting coat color mutant allele of Sox10
GXD Expression
Probe: MGI:3055733
Assay Type: RNA in situ
Annotation Date: 2004-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666816
Pattern: Single cells
Stage: TS16
Assay Id: MGI:3055734
Age: embryonic day 10.0
Image: 6.B
Note: Sox10 marks cell in the Dorsal Root Ganglion of Neural Crest origin. Segmentation in the caudal region at the hindlimg level is disturbed
Specimen Label: 6.B
Detected: true
Specimen Num: 2
Publication
First Author: Harmacek L
Year: 2014
Journal: Dev Neurobiol
Title: A unique missense allele of BAF155, a core BAF chromatin remodeling complex protein, causes neural tube closure defects in mice.
Volume: 74
Issue: 5
Pages: 483-97
Publication
First Author: Silver DL
Year: 2013
Journal: Dev Biol
Title: The EJC component Magoh regulates proliferation and expansion of neural crest-derived melanocytes.
Volume: 375
Issue: 2
Pages: 172-81
Allele  
Name: modifier of Sox10 3
Allele Type: Chemically induced (ENU)
Publication
First Author: Ludwig A
Year: 2004
Journal: Genesis
Title: Sox10-rtTA mouse line for tetracycline-inducible expression of transgenes in neural crest cells and oligodendrocytes.
Volume: 40
Issue: 3
Pages: 171-5
Publication
First Author: Suzuki N
Year: 2017
Journal: Sci Rep
Title: Differentiation of Oligodendrocyte Precursor Cells from Sox10-Venus Mice to Oligodendrocytes and Astrocytes.
Volume: 7
Issue: 1
Pages: 14133
Publication
First Author: Corpening JC
Year: 2011
Journal: Genesis
Title: Isolation and live imaging of enteric progenitors based on Sox10-Histone2BVenus transgene expression.
Volume: 49
Issue: 7
Pages: 599-618
Publication
First Author: Southard-Smith EM
Year: 1999
Journal: Genome Res
Title: The Sox10(Dom) mouse: modeling the genetic variation of Waardenburg-Shah (WS4) syndrome.
Volume: 9
Issue: 3
Pages: 215-25
Publication
First Author: Yu W
Year: 2020
Journal: Stem Cells Dev
Title: SOX10-Cre-Labeled Cells Under the Tongue Epithelium Serve as Progenitors for Taste Bud Cells That Are Mainly Type III and Keratin 8-Low.
Volume: 29
Issue: 10
Pages: 638-647
Publication
First Author: Musser MA
Year: 2015
Journal: Cell Mol Gastroenterol Hepatol
Title: Enteric neuron imbalance and proximal dysmotility in ganglionated intestine of the Sox10Dom/+ Hirschsprung mouse model.
Volume: 1
Issue: 1
Pages: 87-101
Publication
First Author: Hu X
Year: 2021
Journal: J Neurosci
Title: Sustained ErbB Activation Causes Demyelination and Hypomyelination by Driving Necroptosis of Mature Oligodendrocytes and Apoptosis of Oligodendrocyte Precursor Cells.
Volume: 41
Issue: 48
Pages: 9872-9890
Publication
First Author: Weider M
Year: 2018
Journal: Nat Commun
Title: Nfat/calcineurin signaling promotes oligodendrocyte differentiation and myelination by transcription factor network tuning.
Volume: 9
Issue: 1
Pages: 899
Publication  
First Author: Keuls RA
Year: 2021
Journal: Front Cell Neurosci
Title: Single-Cell Multiomic Approaches Reveal Diverse Labeling of the Nervous System by Common Cre-Drivers.
Volume: 15
Pages: 648570
Publication
First Author: Owens SE
Year: 2005
Journal: Hum Mol Genet
Title: Genome-wide linkage identifies novel modifier loci of aganglionosis in the Sox10Dom model of Hirschsprung disease.
Volume: 14
Issue: 11
Pages: 1549-58
Publication
First Author: Stanchina L
Year: 2006
Journal: Dev Biol
Title: Interactions between Sox10, Edn3 and Ednrb during enteric nervous system and melanocyte development.
Volume: 295
Issue: 1
Pages: 232-49
Publication
First Author: Liu JA
Year: 2015
Journal: Gastroenterology
Title: Identification of GLI Mutations in Patients With Hirschsprung Disease That Disrupt Enteric Nervous System Development in Mice.
Volume: 149
Issue: 7
Pages: 1837-1848.e5
Publication
First Author: Fufa TD
Year: 2015
Journal: Hum Mol Genet
Title: Genomic analysis reveals distinct mechanisms and functional classes of SOX10-regulated genes in melanocytes.
Volume: 24
Issue: 19
Pages: 5433-50
Publication
First Author: Jones EA
Year: 2011
Journal: J Neurosci
Title: Regulation of the PMP22 gene through an intronic enhancer.
Volume: 31
Issue: 11
Pages: 4242-50
Publication
First Author: Agarwal P
Year: 2011
Journal: Development
Title: The MADS box transcription factor MEF2C regulates melanocyte development and is a direct transcriptional target and partner of SOX10.
Volume: 138
Issue: 12
Pages: 2555-65
Publication
First Author: Reiprich S
Year: 2008
Journal: Mol Biol Cell
Title: SoxE proteins are differentially required in mouse adrenal gland development.
Volume: 19
Issue: 4
Pages: 1575-86
Publication
First Author: Weider M
Year: 2015
Journal: PLoS Genet
Title: Elevated in vivo levels of a single transcription factor directly convert satellite glia into oligodendrocyte-like cells.
Volume: 11
Issue: 2
Pages: e1005008
Publication
First Author: Motohashi T
Year: 2011
Journal: Dev Dyn
Title: Neural crest cells retain their capability for multipotential differentiation even after lineage-restricted stages.
Volume: 240
Issue: 7
Pages: 1681-93
Publication
First Author: Cheng Y
Year: 2000
Journal: Brain Res Dev Brain Res
Title: Chick sox10, a transcription factor expressed in both early neural crest cells and central nervous system.
Volume: 121
Issue: 2
Pages: 233-41