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Search results 1 to 100 out of 243 for Mlkl

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Category: Publication
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Type Details Score
Publication
35344427 | J:334165
First Author: Guo J
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Blockage of MLKL prevents myelin damage in experimental diabetic neuropathy.
Volume: 119
Issue: 14
Pages: e2121552119
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Publication
30738250 | J:295288
 
First Author: Zhang J
Year: 2019
Journal: Mol Immunol
Title: MLKL deficiency inhibits DSS-induced colitis independent of intestinal microbiota.
Volume: 107
Pages: 132-141
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Publication
23835476 | J:204622
First Author: Wu J
Year: 2013
Journal: Cell Res
Title: Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis.
Volume: 23
Issue: 8
Pages: 994-1006
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Publication
30837196 | J:292167
 
First Author: Xu H
Year: 2019
Journal: Mol Metab
Title: The pseudokinase MLKL regulates hepatic insulin sensitivity independently of inflammation.
Volume: 23
Pages: 14-23
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Publication
24012422 | J:204620
First Author: Murphy JM
Year: 2013
Journal: Immunity
Title: The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism.
Volume: 39
Issue: 3
Pages: 443-53
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Publication
26549703 | J:250478
First Author: Amini P
Year: 2016
Journal: Eur J Immunol
Title: NET formation can occur independently of RIPK3 and MLKL signaling.
Volume: 46
Issue: 1
Pages: 178-84
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Publication
33767595 | J:308937
First Author: Zhao Q
Year: 2021
Journal: Int J Biol Sci
Title: MLKL inhibits intestinal tumorigenesis by suppressing STAT3 signaling pathway.
Volume: 17
Issue: 3
Pages: 869-881
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Publication
30181240 | J:281925
 
First Author: D'Cruz AA
Year: 2018
Journal: Sci Signal
Title: The pseudokinase MLKL activates PAD4-dependent NET formation in necroptotic neutrophils.
Volume: 11
Issue: 546
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Publication
31158430 | J:277550
 
First Author: Zhao Q
Year: 2019
Journal: Cancer Lett
Title: MLKL attenuates colon inflammation and colitis-tumorigenesis via suppression of inflammatory responses.
Volume: 459
Pages: 100-111
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Publication
29456533 | J:311184
 
First Author: Yu SX
Year: 2018
Journal: Front Immunol
Title: Non-Hematopoietic MLKL Protects Against Salmonella Mucosal Infection by Enhancing Inflammasome Activation.
Volume: 9
Pages: 119
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Publication
30644439 | J:305139
First Author: Xiong Y
Year: 2019
Journal: Cell Death Differ
Title: The bromodomain protein BRD4 positively regulates necroptosis via modulating MLKL expression.
Volume: 26
Issue: 10
Pages: 1929-1941
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Publication
28096356 | J:240607
First Author: Conos SA
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner.
Volume: 114
Issue: 6
Pages: E961-E969
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Publication
34099649 | J:343897
First Author: Garcia LR
Year: 2021
Journal: Nat Commun
Title: Ubiquitylation of MLKL at lysine 219 positively regulates necroptosis-induced tissue injury and pathogen clearance.
Volume: 12
Issue: 1
Pages: 3364
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Publication
30344099 | J:268833
First Author: Ying Z
Year: 2018
Journal: Mol Cell
Title: Mixed Lineage Kinase Domain-like Protein MLKL Breaks Down Myelin following Nerve Injury.
Volume: 72
Issue: 3
Pages: 457-468.e5
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Publication
35173541 | J:321571
First Author: Chen H
Year: 2022
Journal: Int J Biol Sci
Title: The role of MLKL in Hepatic Ischemia-Reperfusion Injury of Alcoholic Steatotic Livers.
Volume: 18
Issue: 3
Pages: 1096-1106
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Publication
26104484 | J:223015
 
First Author: Kang S
Year: 2015
Journal: Nat Commun
Title: Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3.
Volume: 6
Pages: 7515
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Publication
24316671 | J:208282
First Author: Cai Z
Year: 2014
Journal: Nat Cell Biol
Title: Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis.
Volume: 16
Issue: 1
Pages: 55-65
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Publication
24703947 | J:213143
First Author: Wang H
Year: 2014
Journal: Mol Cell
Title: Mixed lineage kinase domain-like protein MLKL causes necrotic membrane disruption upon phosphorylation by RIP3.
Volume: 54
Issue: 1
Pages: 133-146
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Publication
27498868 | J:238962
First Author: Zhang X
Year: 2016
Journal: Cell Rep
Title: MLKL and FADD Are Critical for Suppressing Progressive Lymphoproliferative Disease and Activating the NLRP3 Inflammasome.
Volume: 16
Issue: 12
Pages: 3247-3259
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Publication
30975711 | J:276680
First Author: Sai K
Year: 2019
Journal: J Cell Biol
Title: Necroptosis mediators RIPK3 and MLKL suppress intracellular Listeria replication independently of host cell killing.
Volume: 218
Issue: 6
Pages: 1994-2005
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Publication
30842945 | J:280220
 
First Author: Moerke C
Year: 2019
Journal: Front Cell Dev Biol
Title: Combined Knockout of RIPK3 and MLKL Reveals Unexpected Outcome in Tissue Injury and Inflammation.
Volume: 7
Pages: 19
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Publication
26283547 | J:237021
First Author: Tanzer MC
Year: 2015
Journal: Biochem J
Title: Necroptosis signalling is tuned by phosphorylation of MLKL residues outside the pseudokinase domain activation loop.
Volume: 471
Issue: 2
Pages: 255-65
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Publication
33210566 | J:340128
First Author: Lule S
Year: 2021
Journal: J Cereb Blood Flow Metab
Title: Cell-specific activation of RIPK1 and MLKL after intracerebral hemorrhage in mice.
Volume: 41
Issue: 7
Pages: 1623-1633
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Publication
26024392 | J:258653
First Author: Rodriguez DA
Year: 2016
Journal: Cell Death Differ
Title: Characterization of RIPK3-mediated phosphorylation of the activation loop of MLKL during necroptosis.
Volume: 23
Issue: 1
Pages: 76-88
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32457484 | J:332433
First Author: Seo J
Year: 2020
Journal: Cell Death Differ
Title: Beclin 1 functions as a negative modulator of MLKL oligomerisation by integrating into the necrosome complex.
Volume: 27
Issue: 11
Pages: 3065-3081
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27756058 | J:239618
First Author: Günther C
Year: 2016
Journal: J Clin Invest
Title: The pseudokinase MLKL mediates programmed hepatocellular necrosis independently of RIPK3 during hepatitis.
Volume: 126
Issue: 11
Pages: 4346-4360
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Publication
32561755 | J:292274
First Author: Hildebrand JM
Year: 2020
Journal: Nat Commun
Title: A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction.
Volume: 11
Issue: 1
Pages: 3150
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29786074 | J:275025
First Author: Sarhan J
Year: 2019
Journal: Cell Death Differ
Title: Constitutive interferon signaling maintains critical threshold of MLKL expression to license necroptosis.
Volume: 26
Issue: 2
Pages: 332-347
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Publication
27523270 | J:254600
First Author: Alvarez-Diaz S
Year: 2016
Journal: Immunity
Title: The Pseudokinase MLKL and the Kinase RIPK3 Have Distinct Roles in Autoimmune Disease Caused by Loss of Death-Receptor-Induced Apoptosis.
Volume: 45
Issue: 3
Pages: 513-526
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25288762 | J:216425
First Author: Hildebrand JM
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death.
Volume: 111
Issue: 42
Pages: 15072-7
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Publication
30143632 | J:266094
First Author: Van Hoecke L
Year: 2018
Journal: Nat Commun
Title: Treatment with mRNA coding for the necroptosis mediator MLKL induces antitumor immunity directed against neo-epitopes.
Volume: 9
Issue: 1
Pages: 3417
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Publication
27177019 | J:258651
First Author: Newton K
Year: 2016
Journal: Cell Death Differ
Title: RIPK3 deficiency or catalytically inactive RIPK1 provides greater benefit than MLKL deficiency in mouse models of inflammation and tissue injury.
Volume: 23
Issue: 9
Pages: 1565-76
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35422482 | J:324042
First Author: Martens S
Year: 2022
Journal: Cell Death Dis
Title: MLKL deficiency in BrafV600EPten-/- melanoma model results in a modest delay of nevi development and reduced lymph node dissemination in male mice.
Volume: 13
Issue: 4
Pages: 347
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Publication
- | J:272831
     
First Author: Wang Y
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Ghoulish.
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Publication
31019504 | J:284320
 
First Author: Riegler AN
Year: 2019
Journal: Front Immunol
Title: Necroptotic Cell Death Promotes Adaptive Immunity Against Colonizing Pneumococci.
Volume: 10
Pages: 615
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38022500 | J:343321
 
First Author: Pefanis A
Year: 2023
Journal: Front Immunol
Title: Dynamics of necroptosis in kidney ischemia-reperfusion injury.
Volume: 14
Pages: 1251452
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26868910 | J:258857
First Author: Tanzer MC
Year: 2016
Journal: Cell Death Differ
Title: Evolutionary divergence of the necroptosis effector MLKL.
Volume: 23
Issue: 7
Pages: 1185-97
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22265413 | J:201938
First Author: Sun L
Year: 2012
Journal: Cell
Title: Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase.
Volume: 148
Issue: 1-2
Pages: 213-27
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24095729 | J:204592
First Author: Xie T
Year: 2013
Journal: Cell Rep
Title: Structural insights into RIP3-mediated necroptotic signaling.
Volume: 5
Issue: 1
Pages: 70-8
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33510145 | J:314601
First Author: Moujalled D
Year: 2021
Journal: Cell Death Dis
Title: The necroptotic cell death pathway operates in megakaryocytes, but not in platelet synthesis.
Volume: 12
Issue: 1
Pages: 133
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27321907 | J:289088
First Author: Nogusa S
Year: 2016
Journal: Cell Host Microbe
Title: RIPK3 Activates Parallel Pathways of MLKL-Driven Necroptosis and FADD-Mediated Apoptosis to Protect against Influenza A Virus.
Volume: 20
Issue: 1
Pages: 13-24
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36774342 | J:339743
First Author: Patton T
Year: 2023
Journal: Cell Death Dis
Title: RIPK3 controls MAIT cell accumulation during development but not during infection.
Volume: 14
Issue: 2
Pages: 111
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Publication
28807105 | J:256680
   
First Author: Li D
Year: 2017
Journal: Elife
Title: RIPK1-RIPK3-MLKL-dependent necrosis promotes the aging of mouse male reproductive system.
Volume: 6
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26531064 | J:249849
First Author: Desai J
Year: 2016
Journal: Eur J Immunol
Title: PMA and crystal-induced neutrophil extracellular trap formation involves RIPK1-RIPK3-MLKL signaling.
Volume: 46
Issue: 1
Pages: 223-9
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Publication
29746630 | J:277759
First Author: Yang J
Year: 2018
Journal: Cereb Cortex
Title: RIPK3/MLKL-Mediated Neuronal Necroptosis Modulates the M1/M2 Polarization of Microglia/Macrophages in the Ischemic Cortex.
Volume: 28
Issue: 7
Pages: 2622-2635
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Publication
37511074 | J:339119
 
First Author: Yan M
Year: 2023
Journal: Int J Mol Sci
Title: Targeting Endothelial Necroptosis Disrupts Profibrotic Endothelial-Hepatic Stellate Cells Crosstalk to Alleviate Liver Fibrosis in Nonalcoholic Steatohepatitis.
Volume: 24
Issue: 14
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25316792 | J:216677
First Author: Wang X
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Direct activation of RIP3/MLKL-dependent necrosis by herpes simplex virus 1 (HSV-1) protein ICP6 triggers host antiviral defense.
Volume: 111
Issue: 43
Pages: 15438-43
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32200799 | J:289082
First Author: Zhang T
Year: 2020
Journal: Cell
Title: Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis.
Volume: 180
Issue: 6
Pages: 1115-1129.e13
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Publication
26817517 | J:236068
 
First Author: Mulay SR
Year: 2016
Journal: Nat Commun
Title: Cytotoxicity of crystals involves RIPK3-MLKL-mediated necroptosis.
Volume: 7
Pages: 10274
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29167229 | J:255496
First Author: Xu C
Year: 2018
Journal: J Immunol
Title: Embryonic Lethality and Host Immunity of RelA-Deficient Mice Are Mediated by Both Apoptosis and Necroptosis.
Volume: 200
Issue: 1
Pages: 271-285
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28387756 | J:268620
First Author: González-Juarbe N
Year: 2017
Journal: Cell Death Differ
Title: Pore-forming toxin-mediated ion dysregulation leads to death receptor-independent necroptosis of lung epithelial cells during bacterial pneumonia.
Volume: 24
Issue: 5
Pages: 917-928
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22421439 | J:182661
First Author: Zhao J
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis.
Volume: 109
Issue: 14
Pages: 5322-7
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34753914 | J:322024
First Author: Wu L
Year: 2021
Journal: Cell Death Dis
Title: Genetic inhibition of RIPK3 ameliorates functional outcome in controlled cortical impact independent of necroptosis.
Volume: 12
Issue: 11
Pages: 1064
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32315377 | J:294928
 
First Author: Devos M
Year: 2020
Journal: J Exp Med
Title: Sensing of endogenous nucleic acids by ZBP1 induces keratinocyte necroptosis and skin inflammation.
Volume: 217
Issue: 7
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31819256 | J:290374
First Author: Speir M
Year: 2020
Journal: Nat Immunol
Title: Ptpn6 inhibits caspase-8- and Ripk3/Mlkl-dependent inflammation.
Volume: 21
Issue: 1
Pages: 54-64
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28666573 | J:258144
First Author: Yoon S
Year: 2017
Journal: Immunity
Title: MLKL, the Protein that Mediates Necroptosis, Also Regulates Endosomal Trafficking and Extracellular Vesicle Generation.
Volume: 47
Issue: 1
Pages: 51-65.e7
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28366204 | J:241350
First Author: Daniels BP
Year: 2017
Journal: Cell
Title: RIPK3 Restricts Viral Pathogenesis via Cell Death-Independent Neuroinflammation.
Volume: 169
Issue: 2
Pages: 301-313.e11
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32428502 | J:296046
First Author: Tummers B
Year: 2020
Journal: Immunity
Title: Caspase-8-Dependent Inflammatory Responses Are Controlled by Its Adaptor, FADD, and Necroptosis.
Volume: 52
Issue: 6
Pages: 994-1006.e8
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34625557 | J:312467
First Author: Schünke H
Year: 2021
Journal: Nat Commun
Title: OTULIN inhibits RIPK1-mediated keratinocyte necroptosis to prevent skin inflammation in mice.
Volume: 12
Issue: 1
Pages: 5912
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34798063 | J:317682
First Author: Howard JE
Year: 2021
Journal: Stem Cell Reports
Title: IL-18R-mediated HSC quiescence and MLKL-dependent cell death limit hematopoiesis during infection-induced shock.
Volume: 16
Issue: 12
Pages: 2887-2899
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31026418 | J:277210
First Author: Ni HM
Year: 2019
Journal: Am J Pathol
Title: Receptor-Interacting Serine/Threonine-Protein Kinase 3 (RIPK3)-Mixed Lineage Kinase Domain-Like Protein (MLKL)-Mediated Necroptosis Contributes to Ischemia-Reperfusion Injury of Steatotic Livers.
Volume: 189
Issue: 7
Pages: 1363-1374
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32703968 | J:292377
First Author: Zhang Y
Year: 2020
Journal: Cell Death Dis
Title: Catalytically inactive RIP1 and RIP3 deficiency protect against acute ischemic stroke by inhibiting necroptosis and neuroinflammation.
Volume: 11
Issue: 7
Pages: 565
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31985117 | J:298113
First Author: Webster JD
Year: 2020
Journal: J Leukoc Biol
Title: RIP1 kinase activity is critical for skin inflammation but not for viral propagation.
Volume: 107
Issue: 6
Pages: 941-952
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30837313 | J:272956
First Author: Zhang S
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: RIP1 kinase inhibitor halts the progression of an immune-induced demyelination disease at the stage of monocyte elevation.
Volume: 116
Issue: 12
Pages: 5675-5680
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31506635 | J:296530
First Author: Lin QS
Year: 2020
Journal: Lab Invest
Title: RIP1/RIP3/MLKL mediates dopaminergic neuron necroptosis in a mouse model of Parkinson disease.
Volume: 100
Issue: 3
Pages: 503-511
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33862457 | J:305584
 
First Author: Kim TY
Year: 2021
Journal: Biochem Biophys Res Commun
Title: Down-regulation of pro-necroptotic molecules blunts necroptosis during myogenesis.
Volume: 557
Pages: 33-39
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29212904 | J:284973
First Author: O'Donnell JA
Year: 2018
Journal: J Immunol
Title: Dendritic Cell RIPK1 Maintains Immune Homeostasis by Preventing Inflammation and Autoimmunity.
Volume: 200
Issue: 2
Pages: 737-748
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31141691 | J:281881
First Author: Zhang J
Year: 2019
Journal: Cell Rep
Title: Ubiquitin Ligases cIAP1 and cIAP2 Limit Cell Death to Prevent Inflammation.
Volume: 27
Issue: 9
Pages: 2679-2689.e3
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34625556 | J:312394
First Author: Hoste E
Year: 2021
Journal: Nat Commun
Title: OTULIN maintains skin homeostasis by controlling keratinocyte death and stem cell identity.
Volume: 12
Issue: 1
Pages: 5913
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27819681 | J:242991
First Author: Lin J
Year: 2016
Journal: Nature
Title: RIPK1 counteracts ZBP1-mediated necroptosis to inhibit inflammation.
Volume: 540
Issue: 7631
Pages: 124-128
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25693118 | J:221796
 
First Author: Lawlor KE
Year: 2015
Journal: Nat Commun
Title: RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL.
Volume: 6
Pages: 6282
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23612963 | J:199609
First Author: Chen W
Year: 2013
Journal: J Biol Chem
Title: Diverse sequence determinants control human and mouse receptor interacting protein 3 (RIP3) and mixed lineage kinase domain-like (MLKL) interaction in necroptotic signaling.
Volume: 288
Issue: 23
Pages: 16247-61
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28151480 | J:321619
First Author: Hänggi K
Year: 2017
Journal: Cell Death Dis
Title: RIPK1/RIPK3 promotes vascular permeability to allow tumor cell extravasation independent of its necroptotic function.
Volume: 8
Issue: 2
Pages: e2588
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29527209 | J:318494
 
First Author: Lusthaus M
Year: 2018
Journal: Front Immunol
Title: Receptor-Interacting Protein Kinases 1 and 3, and Mixed Lineage Kinase Domain-Like Protein Are Activated by Sublytic Complement and Participate in Complement-Dependent Cytotoxicity.
Volume: 9
Pages: 306
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- | J:234252
     
First Author: Wang Y
Year: 2016
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for secro
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- | J:225934
     
First Author: Wang Y
Year: 2015
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for necro
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29101355 | J:256942
First Author: Desai J
Year: 2017
Journal: Sci Rep
Title: Particles of different sizes and shapes induce neutrophil necroptosis followed by the release of neutrophil extracellular trap-like chromatin.
Volume: 7
Issue: 1
Pages: 15003
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32735843 | J:305782
First Author: Doerflinger M
Year: 2020
Journal: Immunity
Title: Flexible Usage and Interconnectivity of Diverse Cell Death Pathways Protect against Intracellular Infection.
Volume: 53
Issue: 3
Pages: 533-547.e7
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32846120 | J:312124
First Author: Gonzalez-Juarbe N
Year: 2020
Journal: Cell Rep
Title: Influenza-Induced Oxidative Stress Sensitizes Lung Cells to Bacterial-Toxin-Mediated Necroptosis.
Volume: 32
Issue: 8
Pages: 108062
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33472399 | J:321054
First Author: Hosseini Z
Year: 2021
Journal: Arterioscler Thromb Vasc Biol
Title: Resolvin D1 Enhances Necroptotic Cell Clearance Through Promoting Macrophage Fatty Acid Oxidation and Oxidative Phosphorylation.
Volume: 41
Issue: 3
Pages: 1062-1075
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32089086 | J:325213
First Author: Shi C
Year: 2020
Journal: Circ Res
Title: Crystal Clots as Therapeutic Target in Cholesterol Crystal Embolism.
Volume: 126
Issue: 8
Pages: e37-e52
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- | J:234251
     
First Author: Wang Y
Year: 2016
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for mecro
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31748744 | J:285930
First Author: Fritsch M
Year: 2019
Journal: Nature
Title: Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis.
Volume: 575
Issue: 7784
Pages: 683-687
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27819682 | J:242990
First Author: Newton K
Year: 2016
Journal: Nature
Title: RIPK1 inhibits ZBP1-driven necroptosis during development.
Volume: 540
Issue: 7631
Pages: 129-133
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31659279 | J:297034
First Author: Someda M
Year: 2020
Journal: Cell Death Differ
Title: Caspase-8, receptor-interacting protein kinase 1 (RIPK1), and RIPK3 regulate retinoic acid-induced cell differentiation and necroptosis.
Volume: 27
Issue: 5
Pages: 1539-1553
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Publication
37576598 | J:339076
 
First Author: Meng H
Year: 2023
Journal: Front Cell Dev Biol
Title: Evidence for developmental vascular-associated necroptosis and its contribution to venous-lymphatic endothelial differentiation.
Volume: 11
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First Author: Dannappel M
Year: 2014
Journal: Nature
Title: RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis.
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First Author: Shindo R
Year: 2019
Journal: iScience
Title: Necroptosis of Intestinal Epithelial Cells Induces Type 3 Innate Lymphoid Cell-Dependent Lethal Ileitis.
Volume: 15
Pages: 536-551
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First Author: Newton K
Year: 2019
Journal: Nature
Title: Cleavage of RIPK1 by caspase-8 is crucial for limiting apoptosis and necroptosis.
Volume: 574
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First Author: Peltzer N
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Journal: Nature
Title: LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis.
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First Author: Bisson N
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Title: Mice lacking both mixed-lineage kinase genes Mlk1 and Mlk2 retain a wild type phenotype.
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First Author: Liu Z
Year: 2021
Journal: Immunity
Title: A class of viral inducer of degradation of the necroptosis adaptor RIPK3 regulates virus-induced inflammation.
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First Author: Liu ZZ
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Journal: Front Immunol
Title: STING Contributes to Host Defense Against Staphylococcus aureus Pneumonia Through Suppressing Necroptosis.
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First Author: Yu X
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First Author: Imamura M
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Journal: JCI Insight
Title: RIPK3 promotes kidney fibrosis via AKT-dependent ATP citrate lyase.
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First Author: Shubina M
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First Author: Raju S
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Journal: JCI Insight
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