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Search results 201 to 300 out of 3322 for Sacs

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Type Details Score
GXD Expression
Probe: MGI:6283351
Assay Type: Immunohistochemistry
Annotation Date: 2019-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803619
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6283371
Age: embryonic day 11.5
Image: 3C
Note: Authors report expression in lymph sacs immediately adjacent to pre-lymphatic clusters.
Specimen Label: 3C
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:5555854
Assay Type: Immunohistochemistry
Annotation Date: 2019-05-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803619
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6303621
Age: embryonic day 11.5
Image: 3J/K
Note: Authors report enlarged lymph sacs in mutatnt embryos complared to wild type embryos.
Specimen Label: 3J/K
Detected: true
Specimen Num: 5
GXD Expression
Probe: MGI:6303617
Assay Type: Immunohistochemistry
Annotation Date: 2019-05-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6303622
Age: embryonic day 14.5
Image: 4J
Note: Authors report enlarge lymph sacs in mutatnt embryos complared to wild type embryos.
Specimen Label: 4J
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:5555852
Assay Type: Immunohistochemistry
Annotation Date: 2019-05-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803619
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6303623
Age: embryonic day 11.5
Image: 3I/K
Note: Authors report enlarged lymph sacs in mutatnt embryos complared to wild type embryos.
Specimen Label: 3I/K
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:5555852
Assay Type: Immunohistochemistry
Annotation Date: 2019-05-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6303623
Age: embryonic day 14.5
Image: 4J
Note: Authors report enlarge lymph sacs in mutatnt embryos complared to wild type embryos.
Specimen Label: 4J
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:5551742
Assay Type: Immunohistochemistry
Annotation Date: 2020-09-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803620
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6454345
Age: embryonic day 12.5
Image: 1D
Note: Lymphatic endothelial cells in the jugular lymph sacs were double positive for Prox1 and LA102.
Specimen Label: 1D
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:6454056
Assay Type: Immunohistochemistry
Annotation Date: 2020-09-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803621
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6454685
Age: embryonic day 13.5
Note: Proliferating Lyve1+/Mki67+ cells were detected in lymph sacs and sprouts from lymph sacs.
Specimen Label: not shown
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:6454053
Assay Type: Immunohistochemistry
Annotation Date: 2020-09-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803621
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6454344
Age: embryonic day 13.5
Note: Proliferating Lyve1+/Mki67+ cells were detected in lymph sacs and sprouts from lymph sacs.
Specimen Label: not shown
Detected: true
Specimen Num: 12
GXD Expression
Probe: MGI:5587807
Assay Type: Immunohistochemistry
Annotation Date: 2021-09-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803621
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6758976
Age: embryonic day 13.5
Image: S2B/C
Note: Many cardiac lymphatic endothelial cells lining the jugular lymph sacs were Isl1+ lineage.
Specimen Label: S2B/C
Detected: true
Specimen Num: 5
Allele
Name: pleckstrin homology like domain, family A, member 2; targeted mutation 1, Benjamin Tycko
Allele Type: Targeted
Attribute String: Null/knockout
GXD Expression  
Probe: MGI:1328239
Assay Type: Immunohistochemistry
Annotation Date: 1999-04-23
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1637014
Stage: TS14
Assay Id: MGI:1334704
Age: embryonic day 9.5
Image: 6F
Note: Lack of vessel assembly in mutant yolk sacs was confirmed by PECAM-1 staining (notwithstanding the presence of some angioblastic cords).
Specimen Label: 6F
Detected: false
Specimen Num: 2
GXD Expression
Probe: MGI:2448748
Assay Type: RNA in situ
Annotation Date: 1999-02-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672825
Pattern: Single cells
Stage: TS25
Assay Id: MGI:1330864
Age: embryonic day 17.5
Image: 2E
Note: Expression was detected in cells lining the lumen of terminal sacs and was strong in widely scattered numerous cells.
Specimen Label: 2E
Detected: true
Specimen Num: 8
GXD Expression
Probe: MGI:2448748
Assay Type: RNA in situ
Annotation Date: 1999-02-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672825
Pattern: Single cells
Stage: TS25
Assay Id: MGI:1330864
Age: embryonic day 17.5
Image: 2G
Note: Expression was detected in cells lining the lumen of terminal sacs and was strong in widely scattered numerous cells.
Specimen Label: 2G
Detected: true
Specimen Num: 10
GXD Expression
Probe: MGI:5660390
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824820
Pattern: Uniform
Stage: TS20
Assay Id: MGI:5660396
Age: embryonic day 12.5
Image: 1B/D
Note: Uniform bilateral expression in jugular lymph sacs endothelial cells. Expressed in nuclei. Coexpressed with Prox1 and Flt4.
Specimen Label: 1B/D
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:5660390
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824820
Pattern: Uniform
Stage: TS20
Assay Id: MGI:5660396
Age: embryonic day 12.5
Image: S1A/C
Note: Uniform bilateral expression in developing jugular lymph sacs endothelial cells and sprouting lymphatic endothelial cells. Coexpressed with Prox1 and Flt4.
Specimen Label: S1A/C
Detected: true
Specimen Num: 13
GXD Expression
Probe: MGI:5660390
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5660396
Age: embryonic day 12.5
Image: S1D
Note: Uniform bilateral expression in developing jugular lymph sacs endothelial cells and sprouting lymphatic endothelial cells. Coexpressed with Prox1 and Pdpn.
Specimen Label: S1D
Detected: true
Specimen Num: 14
GXD Expression
Probe: MGI:5660390
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824820
Pattern: Uniform
Stage: TS20
Assay Id: MGI:5660396
Age: embryonic day 12.5
Image: S1E
Note: Uniform bilateral expression in developing jugular lymph sacs endothelial cells and sprouting lymphatic endothelial cells. Coexpressed with Prox1.
Specimen Label: S1E
Detected: true
Specimen Num: 15
GXD Expression
Probe: MGI:5660391
Assay Type: Immunohistochemistry
Annotation Date: 2015-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824820
Pattern: Uniform
Stage: TS20
Assay Id: MGI:5660554
Age: embryonic day 12.5
Image: S1C
Note: Uniform bilateral expression in developing jugular lymph sacs endothelial cells and sprouting lymphatic endothelial cells. Coexpressed with Prox1 and Nfatc1.
Specimen Label: S1C
Detected: true
Specimen Num: 8
GXD Expression
Probe: MGI:5476703
Assay Type: Immunohistochemistry
Annotation Date: 2015-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5660608
Age: embryonic day 12.5
Image: S1D
Note: Uniform bilateral expression in developing jugular lymph sacs endothelial cells and sprouting lymphatic endothelial cells. Coexpressed with Prox1 and Nfatc1.
Specimen Label: S1D
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:1328239
Assay Type: Immunohistochemistry
Annotation Date: 2022-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3517626
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7377703
Age: embryonic day 18.5
Image: 4I
Note: In this mutant there is a disarrangement of blood capillaries in the terminal air sacs compared to wild-type.
Specimen Label: 4I
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:5634415
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803619
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6437766
Age: embryonic day 11.5
Note: Expression is in lymph sacs near the cardinal vein and is absent in the area towards the craniofacial region.
Specimen Label: 2B
Detected: true
Specimen Num: 4
CL Term
CL Term
CL Term
Allele
Name: pleckstrin homology like domain, family A, member 2; targeted mutation 2, Benjamin Tycko
Allele Type: Targeted
Attribute String: Null/knockout
Strain
Attribute String: congenic, mutant strain, targeted mutation
Publication
First Author: Creeth HDJ
Year: 2018
Journal: PLoS Biol
Title: Maternal care boosted by paternal imprinting in mammals.
Volume: 16
Issue: 7
Pages: e2006599
Publication
First Author: Tunster SJ
Year: 2016
Journal: Dev Biol
Title: The imprinted Phlda2 gene modulates a major endocrine compartment of the placenta to regulate placental demands for maternal resources.
Volume: 409
Issue: 1
Pages: 251-60
Publication
First Author: Tunster SJ
Year: 2016
Journal: Dev Biol
Title: Increased dosage of the imprinted Ascl2 gene restrains two key endocrine lineages of the mouse Placenta.
Volume: 418
Issue: 1
Pages: 55-65
Genotype
Symbol: Phlda2/Phlda2
Background: involves: 129/Sv * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Phlda2/Phlda2<+>
Background: 129S2.Cg-Phlda2
Zygosity: ht
Has Mutant Allele: true
DO Term
GXD Expression
Probe: MGI:3693737
Assay Type: Immunohistochemistry
Annotation Date: 2007-01-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1637015
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:3693892
Age: embryonic day 9.5
Image: 3h
Note: Expression was detected in endothelial cells of blood vessels as in wild type, but the mutant yolk sacs had a blood vessel defect.
Specimen Label: 3h
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5555854
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1735520
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6437759
Age: embryonic day 12.5
Note: Expression is in lymphatic endothelial cells, including individual, aggregated, and forming lymph sacs and lymphatic vessels in the sublingual regions of the mandibular arches.
Specimen Label: 7A
Detected: true
Specimen Num: 33
GXD Expression  
Probe: MGI:5555854
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1735520
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6437759
Age: embryonic day 12.5
Note: Expression is in lymphatic endothelial cells, including individual, aggregated, and forming lymph sacs and lymphatic vessels in the sublingual regions of the mandibular arches.
Specimen Label: 7B
Detected: true
Specimen Num: 34
GXD Expression  
Probe: MGI:5555854
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1735520
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6437759
Age: embryonic day 12.5
Note: Expression is in lymphatic endothelial cells, including individual, aggregated, and forming lymph sacs and lymphatic vessels in the sublingual regions of the mandibular arches.
Specimen Label: 7C
Detected: true
Specimen Num: 35
GXD Expression  
Probe: MGI:5555854
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1735520
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6437759
Age: embryonic day 12.5
Note: Expression is in lymphatic endothelial cells, including individual, aggregated, and forming lymph sacs and lymphatic vessels in the sublingual regions of the mandibular arches.
Specimen Label: 7D
Detected: true
Specimen Num: 36
GXD Expression  
Probe: MGI:4943862
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1735520
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6437762
Age: embryonic day 12.5
Note: Expression is in lymphatic endothelial cells, including individual, aggregated, and forming lymph sacs and lymphatic vessels in the sublingual regions of the mandibular arches.
Specimen Label: 7A
Detected: true
Specimen Num: 20
GXD Expression
Probe: MGI:5476703
Assay Type: Immunohistochemistry
Annotation Date: 2015-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:5660608
Age: embryonic day 11.5
Image: S2A
Note: Expressed in endothelial cells sprouting from the cardinal vein in organized lymph sacs and dispersed single cell clusters. Coexpressed with Prox1.
Specimen Label: S2A
Detected: true
Specimen Num: 5
GXD Expression
Probe: MGI:5476703
Assay Type: Immunohistochemistry
Annotation Date: 2015-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:5660608
Age: embryonic day 11.5
Image: S2B
Note: Expressed in endothelial cells sprouting from the cardinal vein in organized lymph sacs and dispersed single cell clusters. Coexpressed with Prox1.
Specimen Label: S2B
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:5660388
Assay Type: Immunohistochemistry
Annotation Date: 2015-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:5660552
Age: embryonic day 11.5
Image: S2A
Note: Expressed in endothelial cells sprouting from the cardinal vein in organized lymph sacs and dispersed single cell clusters. Coexpressed with Pdpn.
Specimen Label: S2A
Detected: true
Specimen Num: 19
GXD Expression
Probe: MGI:5660388
Assay Type: Immunohistochemistry
Annotation Date: 2015-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:5660552
Age: embryonic day 11.5
Image: S2B
Note: Expressed in endothelial cells sprouting from the cardinal vein in organized lymph sacs and dispersed single cell clusters. Coexpressed with Pdpn.
Specimen Label: S2B
Detected: true
Specimen Num: 20
GXD Expression  
Probe: MGI:3275214
Assay Type: RNA in situ
Annotation Date: 2015-09-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1859224
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:5660813
Age: embryonic day 16.0
Note: Expression was detected in starburst amacrine cells (SAC) in the inner nuclear layer. Migrating SACs in the outer neuroblast layer, which are positive for Isl1, were not labeled.
Specimen Label: 1d
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5555854
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1790622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6437759
Age: embryonic day 14.5
Note: Expression is in lymphatic endothelial cells, including individual, aggregated, and forming lymph sacs and lymphatic vessels in the sublingual regions of the mandibular arches.
Specimen Label: 7E
Detected: true
Specimen Num: 37
GXD Expression  
Probe: MGI:5555854
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1790622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6437759
Age: embryonic day 14.5
Note: Expression is in lymphatic endothelial cells, including individual, aggregated, and forming lymph sacs and lymphatic vessels in the sublingual regions of the mandibular arches.
Specimen Label: 7F
Detected: true
Specimen Num: 38
GXD Expression  
Probe: MGI:5555854
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1790622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6437759
Age: embryonic day 14.5
Note: Expression is in lymphatic endothelial cells, including individual, aggregated, and forming lymph sacs and lymphatic vessels in the sublingual regions of the mandibular arches.
Specimen Label: 7G
Detected: true
Specimen Num: 39
GXD Expression  
Probe: MGI:5555854
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1790622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6437759
Age: embryonic day 14.5
Note: Expression is in lymphatic endothelial cells, including individual, aggregated, and forming lymph sacs and lymphatic vessels in the sublingual regions of the mandibular arches.
Specimen Label: 7H
Detected: true
Specimen Num: 40
GXD Expression  
Probe: MGI:4943862
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1790622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6437762
Age: embryonic day 14.5
Note: Expression is in lymphatic endothelial cells, including individual, aggregated, and forming lymph sacs and lymphatic vessels in the sublingual regions of the mandibular arches.
Specimen Label: 7E
Detected: true
Specimen Num: 21
GXD Expression  
Probe: MGI:5555854
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803620
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6437759
Age: embryonic day 12.5
Note: Expression is in lymphatic endothelial cells, including individual, aggregated, and forming lymph sacs and lymphatic vessels in the sublingual regions of the mandibular arches.
Specimen Label: 7A
Detected: true
Specimen Num: 33
GXD Expression  
Probe: MGI:5555854
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803620
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6437759
Age: embryonic day 12.5
Note: Expression is in lymphatic endothelial cells, including individual, aggregated, and forming lymph sacs and lymphatic vessels in the sublingual regions of the mandibular arches.
Specimen Label: 7B
Detected: true
Specimen Num: 34
GXD Expression  
Probe: MGI:5555854
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803620
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6437759
Age: embryonic day 12.5
Note: Expression is in lymphatic endothelial cells, including individual, aggregated, and forming lymph sacs and lymphatic vessels in the sublingual regions of the mandibular arches.
Specimen Label: 7C
Detected: true
Specimen Num: 35
GXD Expression  
Probe: MGI:5555854
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803620
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6437759
Age: embryonic day 12.5
Note: Expression is in lymphatic endothelial cells, including individual, aggregated, and forming lymph sacs and lymphatic vessels in the sublingual regions of the mandibular arches.
Specimen Label: 7D
Detected: true
Specimen Num: 36
GXD Expression  
Probe: MGI:5555854
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6437759
Age: embryonic day 14.5
Note: Expression is in lymphatic endothelial cells, including individual, aggregated, and forming lymph sacs and lymphatic vessels in the sublingual regions of the mandibular arches.
Specimen Label: 7E
Detected: true
Specimen Num: 37
GXD Expression  
Probe: MGI:5555854
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6437759
Age: embryonic day 14.5
Note: Expression is in lymphatic endothelial cells, including individual, aggregated, and forming lymph sacs and lymphatic vessels in the sublingual regions of the mandibular arches.
Specimen Label: 7F
Detected: true
Specimen Num: 38
GXD Expression  
Probe: MGI:5555854
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6437759
Age: embryonic day 14.5
Note: Expression is in lymphatic endothelial cells, including individual, aggregated, and forming lymph sacs and lymphatic vessels in the sublingual regions of the mandibular arches.
Specimen Label: 7G
Detected: true
Specimen Num: 39
GXD Expression  
Probe: MGI:5555854
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6437759
Age: embryonic day 14.5
Note: Expression is in lymphatic endothelial cells, including individual, aggregated, and forming lymph sacs and lymphatic vessels in the sublingual regions of the mandibular arches.
Specimen Label: 7H
Detected: true
Specimen Num: 40
GXD Expression  
Probe: MGI:4943862
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803620
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6437762
Age: embryonic day 12.5
Note: Expression is in lymphatic endothelial cells, including individual, aggregated, and forming lymph sacs and lymphatic vessels in the sublingual regions of the mandibular arches.
Specimen Label: 7A
Detected: true
Specimen Num: 20
GXD Expression  
Probe: MGI:4943862
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6437762
Age: embryonic day 14.5
Note: Expression is in lymphatic endothelial cells, including individual, aggregated, and forming lymph sacs and lymphatic vessels in the sublingual regions of the mandibular arches.
Specimen Label: 7E
Detected: true
Specimen Num: 21
GXD Expression  
Probe: MGI:7519199
Assay Type: Immunohistochemistry
Annotation Date: 2023-08-22
Strength: Present
Sex: Female
Emaps: EMAPS:3803622
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7520054
Age: embryonic day 14.5
Note: This mutant had significant dilation of the lymph sacs. The lymph sacs were significantly larger than those of apparently normal knock-outs.
Specimen Label: 6C Female
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:7519199
Assay Type: Immunohistochemistry
Annotation Date: 2023-08-22
Strength: Present
Sex: Male
Emaps: EMAPS:3803622
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7520054
Age: embryonic day 14.5
Note: This mutant had significant dilation of the lymph sacs. The lymph sacs were significantly larger than those of apparently normal knock-outs.
Specimen Label: 6C Male
Detected: true
Specimen Num: 5
GXD Expression
Probe: MGI:5558929
Assay Type: Immunohistochemistry
Annotation Date: 2024-01-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803621
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7574217
Age: embryonic day 13.5
Image: 2C/F
Note: Blood-filled lymph sacs consisted of both Lyve1+ lymphatic and CD31+ blood endothelial cells. The endothelial cells remained close to those of the cardinal veins.
Specimen Label: 2C/F
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:5558929
Assay Type: Immunohistochemistry
Annotation Date: 2024-01-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803621
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7574217
Age: embryonic day 13.5
Image: 2C/F
Note: Blood-filled lymph sacs consisted of both Lyve1+ lymphatic and CD31+ blood endothelial cells. The endothelial cells remained close to those of the cardinal veins.
Specimen Label: 2C/F
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:5558929
Assay Type: Immunohistochemistry
Annotation Date: 2024-01-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803621
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7574217
Age: embryonic day 13.5
Image: 2B/E
Note: Blood-filled lymph sacs consisted of both Lyve1+ lymphatic and CD31+ blood endothelial cells. The endothelial cells remained close to those of the cardinal veins.
Specimen Label: 2B/E
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:5558929
Assay Type: Immunohistochemistry
Annotation Date: 2024-01-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803621
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7574217
Age: embryonic day 13.5
Image: 2B/E
Note: Blood-filled lymph sacs consisted of both Lyve1+ lymphatic and CD31+ blood endothelial cells. The endothelial cells remained close to those of the cardinal veins.
Specimen Label: 2B/E
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:7574151
Assay Type: Immunohistochemistry
Annotation Date: 2024-01-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803621
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7574218
Age: embryonic day 13.5
Image: 2B/E
Note: Blood-filled lymph sacs consisted of both Lyve1+ lymphatic and CD31+ blood endothelial cells. The endothelial cells remained close to those of the cardinal veins.
Specimen Label: 2B/E
Detected: true
Specimen Num: 2
Allele
Name: hematopoietically expressed homeobox; targeted mutation 2, Clifford W Bogue
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
Allele
Name: polycystin 2, transient receptor potential cation channel; targeted mutation 1, Stefan Somlo
Allele Type: Targeted
Attribute String: Hypomorph
Allele  
Name: ovarian teratoma susceptibility 1; LT/Sv
Allele Type: QTL
HT Experiment
Series Id: GSE48146
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Genotype
Symbol: Igf2/Igf2<+> Phlda2/Phlda2<+>
Background: involves: 129/Sv * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Phlda2/Phlda2
Background: involves: 129/Sv * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Phlda2/Phlda2 Phlda3/Phlda3
Background: involves: 129/Sv * C57BL/6
Zygosity: cx
Has Mutant Allele: true
GXD Expression
Probe: MGI:2448748
Assay Type: RNA in situ
Annotation Date: 1999-02-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672825
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:1330864
Age: embryonic day 17.5
Image: 2F
Note: Expression was strong in clustered cells at the proximal tubule and was detected in thin walled tubules of the prospective terminal sacs but in hardly any cells compared to wild type.
Specimen Label: 2F
Detected: true
Specimen Num: 9
GXD Expression
Probe: MGI:2448748
Assay Type: RNA in situ
Annotation Date: 1999-02-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672825
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:1330864
Age: embryonic day 17.5
Image: 2H
Note: Expression was strong in clustered cells at the proximal tubule and was detected in thin walled tubules of the prospective terminal sacs but in hardly any cells compared to wild type.
Specimen Label: 2H
Detected: true
Specimen Num: 11
GXD Expression
Probe: MGI:5555854
Assay Type: Immunohistochemistry
Annotation Date: 2019-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824817
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6283364
Age: embryonic day 10.5
Image: 5E/G
Note: Expression in lymph sacs maintaining a stalklike connection to the cardinal vein at these stages of development. Expression in lymphatic endothelial cells sprouting in a dorso-lateral direction towards the embryo periphery.
Specimen Label: 5E/G
Detected: true
Specimen Num: 22
HT Experiment
Series Id: E-GEOD-60896
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
DO Term
Allele  
Name: renal cystic disease severity; CAST/EiJ
Allele Type: QTL
Allele
Name: deletion, Chr 2, Denis Duboule 39
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele  
Name: BicC family RNA binding protein 1; mutation 1006, J Larry Jameson
Allele Type: Chemically induced (ENU)
Allele
Name: WW domain containing transcription regulator 1; gene trap CSD245, BayGenomics
Allele Type: Gene trapped
Attribute String: Null/knockout, Reporter
QTL
Type: QTL
Organism: mouse, laboratory
MP Term
MP Term
MP Term
MP Term
MP Term
Genotype
Symbol: Ots1/Ots1
Background: involves: C57BL/6J * LT/Sv
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Ots1/Ots1
Background: involves: C57BL/6J * LT/Sv
Zygosity: hm
Has Mutant Allele: true
MP Term
MP Term
MP Term
MP Term
MP Term
MP Term
Genotype
Symbol: Pkd2/Pkd2
Background: involves: 129/Sv * C57BL/6J * SJL
Zygosity: hm
Has Mutant Allele: true
MP Term
MP Term
MP Term
MP Term