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Search results 101 to 200 out of 298 for Eif2ak3

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Type Details Score
GXD Expression
GXD Expression
   
Probe: MGI:3820987
Assay Type: RNA in situ
Annotation Date: 2023-09-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7525207
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6506007
Assay Type: RNA in situ
Annotation Date: 2021-02-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3527522
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6506026
Age: embryonic day 14.5
Image: 2a
Note: Similar expression in enamel knot, cervical loop region and along dental follicle.
Specimen Label: 2a
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6506007
Assay Type: RNA in situ
Annotation Date: 2021-02-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3674122
Pattern: Uniform
Stage: TS22
Assay Id: MGI:6506026
Age: embryonic day 14.5
Image: 2a
Note: Authors report uniform (ubiquitous) expression along epithelium and mesenchyme.
Specimen Label: 2a
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6506007
Assay Type: RNA in situ
Annotation Date: 2021-02-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3674224
Pattern: Uniform
Stage: TS24
Assay Id: MGI:6506026
Age: embryonic day 16.5
Image: 3a
Note: Uniform expression along epithelium and mesenchyme.
Specimen Label: 3a
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6506007
Assay Type: RNA in situ
Annotation Date: 2021-02-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3808524
Pattern: Ubiquitous
Stage: TS24
Assay Id: MGI:6506026
Age: embryonic day 16.5
Image: 3a
Note: Ubiquitous expression in inner enamel epithelium and dental papilla.
Specimen Label: 3a
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6506007
Assay Type: RNA in situ
Annotation Date: 2021-02-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3808022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6506026
Age: embryonic day 14.5
Image: 2a
Note: Similar expression in enamel knot, cervical loop region and along dental follicle.
Specimen Label: 2a
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6506007
Assay Type: RNA in situ
Annotation Date: 2021-02-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3809222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6506026
Age: embryonic day 14.5
Image: 2a
Note: Similar expression in enamel knot, cervical loop region and along dental follicle.
Specimen Label: 2a
Detected: true
Specimen Num: 1
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Publication
23071091 | J:192859
First Author: Gao Y
Year: 2012
Journal: Mol Cell Biol
Title: PERK is required in the adult pancreas and is essential for maintenance of glucose homeostasis.
Volume: 32
Issue: 24
Pages: 5129-39
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Publication
21709020 | J:175081
First Author: Avivar-Valderas A
Year: 2011
Journal: Mol Cell Biol
Title: PERK integrates autophagy and oxidative stress responses to promote survival during extracellular matrix detachment.
Volume: 31
Issue: 17
Pages: 3616-29
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Publication
20798685 | J:186981
First Author: Lépine S
Year: 2011
Journal: Cell Death Differ
Title: Sphingosine-1-phosphate phosphohydrolase-1 regulates ER stress-induced autophagy.
Volume: 18
Issue: 2
Pages: 350-61
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Publication
23524851 | J:198373
First Author: Guo C
Year: 2013
Journal: EMBO J
Title: SENP3-mediated deSUMOylation of dynamin-related protein 1 promotes cell death following ischaemia.
Volume: 32
Issue: 11
Pages: 1514-28
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Publication
23921556 | J:200066
First Author: Muñoz JP
Year: 2013
Journal: EMBO J
Title: Mfn2 modulates the UPR and mitochondrial function via repression of PERK.
Volume: 32
Issue: 17
Pages: 2348-61
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Publication
29076578 | J:256284
First Author: VerPlank JJS
Year: 2018
Journal: Glia
Title: Impairment of protein degradation and proteasome function in hereditary neuropathies.
Volume: 66
Issue: 2
Pages: 379-395
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Publication
27807175 | J:236772
First Author: Sidoli M
Year: 2016
Journal: J Neurosci
Title: Ablation of Perk in Schwann Cells Improves Myelination in the S63del Charcot-Marie-Tooth 1B Mouse.
Volume: 36
Issue: 44
Pages: 11350-11361
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Publication
36126165 | J:331950
First Author: Riesenberg BP
Year: 2022
Journal: Cancer Res
Title: Stress-Mediated Attenuation of Translation Undermines T-cell Activity in Cancer.
Volume: 82
Issue: 23
Pages: 4386-4399
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Publication
18049481 | J:146385
First Author: Kudo T
Year: 2008
Journal: Cell Death Differ
Title: A molecular chaperone inducer protects neurons from ER stress.
Volume: 15
Issue: 2
Pages: 364-75
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Publication
15911877 | J:99655
First Author: Lin W
Year: 2005
Journal: J Cell Biol
Title: Endoplasmic reticulum stress modulates the response of myelinating oligodendrocytes to the immune cytokine interferon-gamma.
Volume: 169
Issue: 4
Pages: 603-12
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Publication
19783659 | J:269837
First Author: Bunpo P
Year: 2009
Journal: J Biol Chem
Title: GCN2 protein kinase is required to activate amino acid deprivation responses in mice treated with the anti-cancer agent L-asparaginase.
Volume: 284
Issue: 47
Pages: 32742-9
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Publication
29337352 | J:264586
First Author: Zimmermann HR
Year: 2018
Journal: J Neurochem
Title: Genetic removal of eIF2α kinase PERK in mice enables hippocampal L-LTP independent of mTORC1 activity.
Volume: 146
Issue: 2
Pages: 133-144
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Publication
29718201 | J:265094
First Author: Grande V
Year: 2018
Journal: Hum Mol Genet
Title: PERK inhibition delays neurodegeneration and improves motor function in a mouse model of Marinesco-Sjögren syndrome.
Volume: 27
Issue: 14
Pages: 2477-2489
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Publication
35501370 | J:340415
First Author: Zhang D
Year: 2022
Journal: Nat Cell Biol
Title: A non-canonical cGAS-STING-PERK pathway facilitates the translational program critical for senescence and organ fibrosis.
Volume: 24
Issue: 5
Pages: 766-782
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Publication
23933749 | J:203865
First Author: Ma T
Year: 2013
Journal: Nat Neurosci
Title: Suppression of eIF2α kinases alleviates Alzheimer's disease-related plasticity and memory deficits.
Volume: 16
Issue: 9
Pages: 1299-305
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Publication
21285438 | J:170501
First Author: Nanua S
Year: 2011
Journal: Blood
Title: Activation of the unfolded protein response is associated with impaired granulopoiesis in transgenic mice expressing mutant Elane.
Volume: 117
Issue: 13
Pages: 3539-47
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Publication
26627716 | J:228322
First Author: Yu Q
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Type I interferons mediate pancreatic toxicities of PERK inhibition.
Volume: 112
Issue: 50
Pages: 15420-5
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Publication
33592173 | J:303734
First Author: Latorre-Muro P
Year: 2021
Journal: Cell Metab
Title: A cold-stress-inducible PERK/OGT axis controls TOM70-assisted mitochondrial protein import and cristae formation.
Volume: 33
Issue: 3
Pages: 598-614.e7
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Publication
24481666 | J:207477
First Author: Hussien Y
Year: 2014
Journal: Glia
Title: Genetic inactivation of PERK signaling in mouse oligodendrocytes: normal developmental myelination with increased susceptibility to inflammatory demyelination.
Volume: 62
Issue: 5
Pages: 680-91
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Publication
32661025 | J:294220
First Author: Lei Z
Year: 2020
Journal: J Neurosci
Title: NF-κB Activation Accounts for the Cytoprotective Effects of PERK Activation on Oligodendrocytes during EAE.
Volume: 40
Issue: 33
Pages: 6444-6456
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Publication
30553965 | J:272889
First Author: Liu Z
Year: 2019
Journal: Exp Cell Res
Title: PERK is essential for proliferation of intestinal stem cells in mice.
Volume: 375
Issue: 1
Pages: 42-51
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Publication
17325203 | J:119826
First Author: Shang J
Year: 2007
Journal: J Cell Biol
Title: Translation attenuation by PERK balances ER glycoprotein synthesis with lipid-linked oligosaccharide flux.
Volume: 176
Issue: 5
Pages: 605-16
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Publication
26483256 | J:328974
First Author: Barati MT
Year: 2016
Journal: Cell Stress Chaperones
Title: Differential expression of endoplasmic reticulum stress-response proteins in different renal tubule subtypes of OVE26 diabetic mice.
Volume: 21
Issue: 1
Pages: 155-166
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Publication
33500333 | J:322149
 
First Author: Shimizu T
Year: 2021
Journal: Sci Signal
Title: PERK inhibition attenuates vascular remodeling in pulmonary arterial hypertension caused by BMPR2 mutation.
Volume: 14
Issue: 667
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Publication
34549728 | J:335833
 
First Author: He Z
Year: 2021
Journal: JCI Insight
Title: PERK in POMC neurons connects celastrol with metabolism.
Volume: 6
Issue: 18
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Publication
28948615 | J:258331
First Author: Zhang M
Year: 2017
Journal: FEBS Lett
Title: NDRG2 acts as a PERK co-factor to facilitate PERK branch and ERS-induced cell death.
Volume: 591
Issue: 21
Pages: 3670-3681
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Publication
15314157 | J:92781
First Author: Blais JD
Year: 2004
Journal: Mol Cell Biol
Title: Activating transcription factor 4 is translationally regulated by hypoxic stress.
Volume: 24
Issue: 17
Pages: 7469-82
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Publication
20530744 | J:169638
First Author: Gupta S
Year: 2010
Journal: Diabetes
Title: PERK (EIF2AK3) regulates proinsulin trafficking and quality control in the secretory pathway.
Volume: 59
Issue: 8
Pages: 1937-47
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Publication
24958502 | J:281019
First Author: Liu X
Year: 2014
Journal: Hypertension
Title: Endoplasmic reticulum stress sensor protein kinase R-like endoplasmic reticulum kinase (PERK) protects against pressure overload-induced heart failure and lung remodeling.
Volume: 64
Issue: 4
Pages: 738-44
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Publication
32617517 | J:295192
First Author: Cardoso AC
Year: 2020
Journal: Nat Metab
Title: Mitochondrial Substrate Utilization Regulates Cardiomyocyte Cell Cycle Progression.
Volume: 2
Issue: 2
Pages: 167-178
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Publication
12865332 | J:84818
First Author: Li Y
Year: 2003
Journal: Endocrinology
Title: PERK eIF2alpha kinase regulates neonatal growth by controlling the expression of circulating insulin-like growth factor-I derived from the liver.
Volume: 144
Issue: 8
Pages: 3505-13
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Publication
18852460 | J:141100
First Author: Bobrovnikova-Marjon E
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: PERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiation.
Volume: 105
Issue: 42
Pages: 16314-9
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Publication
30118681 | J:266458
First Author: Chang TK
Year: 2018
Journal: Mol Cell
Title: Coordination between Two Branches of the Unfolded Protein Response Determines Apoptotic Cell Fate.
Volume: 71
Issue: 4
Pages: 629-636.e5
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Publication
11430819 | J:70005
First Author: Harding HP
Year: 2001
Journal: Mol Cell
Title: Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival.
Volume: 7
Issue: 6
Pages: 1153-63
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Publication
27181404 | J:234016
First Author: Ho Y
Year: 2016
Journal: Am J Pathol
Title: PERK Activation Promotes Medulloblastoma Tumorigenesis by Attenuating Premalignant Granule Cell Precursor Apoptosis.
Volume: 186
Issue: 7
Pages: 1939-51
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Publication
29335505 | J:260150
First Author: Hisanaga S
Year: 2018
Journal: Sci Rep
Title: PERK-mediated translational control is required for collagen secretion in chondrocytes.
Volume: 8
Issue: 1
Pages: 773
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Publication
17475769 | J:127460
First Author: Mazroui R
Year: 2007
Journal: Mol Biol Cell
Title: Inhibition of the ubiquitin-proteasome system induces stress granule formation.
Volume: 18
Issue: 7
Pages: 2603-18
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Publication
20661282 | J:163090
First Author: Yang L
Year: 2010
Journal: PLoS One
Title: A Phos-tag-based approach reveals the extent of physiological endoplasmic reticulum stress.
Volume: 5
Issue: 7
Pages: e11621
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Publication
21193559 | J:182887
First Author: Moore CE
Year: 2011
Journal: Mol Endocrinol
Title: PERK activation at low glucose concentration is mediated by SERCA pump inhibition and confers preemptive cytoprotection to pancreatic β-cells.
Volume: 25
Issue: 2
Pages: 315-26
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Publication
23068609 | J:190704
First Author: Gupta S
Year: 2012
Journal: FEBS Lett
Title: NOXA contributes to the sensitivity of PERK-deficient cells to ER stress.
Volume: 586
Issue: 22
Pages: 4023-30
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Publication
25986605 | J:223302
   
First Author: Mendez AS
Year: 2015
Journal: Elife
Title: Endoplasmic reticulum stress-independent activation of unfolded protein response kinases by a small molecule ATP-mimic.
Volume: 4
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Publication
26753564 | J:316517
 
First Author: Vandewynckel YP
Year: 2016
Journal: BMC Cancer
Title: Placental growth factor inhibition modulates the interplay between hypoxia and unfolded protein response in hepatocellular carcinoma.
Volume: 16
Pages: 9
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Publication
9930704 | J:51759
First Author: Harding HP
Year: 1999
Journal: Nature
Title: Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase.
Volume: 397
Issue: 6716
Pages: 271-4
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Publication
25329545 | J:218404
First Author: Roobol A
Year: 2015
Journal: Biochem J
Title: p58IPK is an inhibitor of the eIF2α kinase GCN2 and its localization and expression underpin protein synthesis and ER processing capacity.
Volume: 465
Issue: 2
Pages: 213-25
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Publication
14676213 | J:217285
First Author: Kebache S
Year: 2004
Journal: J Biol Chem
Title: Nck-1 antagonizes the endoplasmic reticulum stress-induced inhibition of translation.
Volume: 279
Issue: 10
Pages: 9662-71
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Publication
29720449 | J:261540
 
First Author: Nguyen HG
Year: 2018
Journal: Sci Transl Med
Title: Development of a stress response therapy targeting aggressive prostate cancer.
Volume: 10
Issue: 439
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Publication
29717162 | J:262984
First Author: Kim KH
Year: 2018
Journal: Sci Rep
Title: Growth differentiation factor 15 ameliorates nonalcoholic steatohepatitis and related metabolic disorders in mice.
Volume: 8
Issue: 1
Pages: 6789
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Publication
17765679 | J:124971
First Author: Wu J
Year: 2007
Journal: Dev Cell
Title: ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress.
Volume: 13
Issue: 3
Pages: 351-64
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Publication
30894532 | J:273454
First Author: Cao Y
Year: 2019
Journal: Nat Commun
Title: ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression.
Volume: 10
Issue: 1
Pages: 1280
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Publication
20221394 | J:158673
First Author: Ghosh R
Year: 2010
Journal: PLoS One
Title: Transcriptional regulation of VEGF-A by the unfolded protein response pathway.
Volume: 5
Issue: 3
Pages: e9575
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Publication
28332979 | J:256686
   
First Author: Xiong G
Year: 2017
Journal: Elife
Title: The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration.
Volume: 6
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Publication
11389192 | J:69887
First Author: Kumar R
Year: 2001
Journal: J Neurochem
Title: Brain ischemia and reperfusion activates the eukaryotic initiation factor 2alpha kinase, PERK.
Volume: 77
Issue: 5
Pages: 1418-21
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Publication
26982722 | J:232715
First Author: Ravindran R
Year: 2016
Journal: Nature
Title: The amino acid sensor GCN2 controls gut inflammation by inhibiting inflammasome activation.
Volume: 531
Issue: 7595
Pages: 523-527
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Publication
32329716 | J:291915
   
First Author: Alvarez-Castelao B
Year: 2020
Journal: Elife
Title: The switch-like expression of heme-regulated kinase 1 mediates neuronal proteostasis following proteasome inhibition.
Volume: 9
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Publication
29449374 | J:262786
First Author: Nikonorova IA
Year: 2018
Journal: J Biol Chem
Title: Time-resolved analysis of amino acid stress identifies eIF2 phosphorylation as necessary to inhibit mTORC1 activity in liver.
Volume: 293
Issue: 14
Pages: 5005-5015
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Publication
30923003 | J:278117
 
First Author: Dzhashiashvili Y
Year: 2019
Journal: Neurobiol Dis
Title: The UPR-PERK pathway is not a promising therapeutic target for mutant SOD1-induced ALS.
Volume: 127
Pages: 527-544
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Publication
28594573 | J:265817
First Author: Khalyfa A
Year: 2017
Journal: Am J Respir Cell Mol Biol
Title: Activation of the Integrated Stress Response and Metabolic Dysfunction in a Murine Model of Sleep Apnea.
Volume: 57
Issue: 4
Pages: 477-486
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Publication
22509299 | J:317568
First Author: Bettaieb A
Year: 2012
Journal: PLoS One
Title: Protein tyrosine phosphatase 1B deficiency potentiates PERK/eIF2α signaling in brown adipocytes.
Volume: 7
Issue: 4
Pages: e34412
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Publication
16923392 | J:115988
First Author: Oyadomari S
Year: 2006
Journal: Cell
Title: Cotranslocational degradation protects the stressed endoplasmic reticulum from protein overload.
Volume: 126
Issue: 4
Pages: 727-39
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Publication
27103515 | J:235030
 
First Author: Yang W
Year: 2016
Journal: Neurobiol Aging
Title: Repression of the eIF2α kinase PERK alleviates mGluR-LTD impairments in a mouse model of Alzheimer's disease.
Volume: 41
Pages: 19-24
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Publication
25956028 | J:222955
First Author: Hiramatsu N
Year: 2015
Journal: Am J Pathol
Title: Multiple Mechanisms of Unfolded Protein Response-Induced Cell Death.
Volume: 185
Issue: 7
Pages: 1800-8
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Publication
30674717 | J:278405
 
First Author: Stone S
Year: 2019
Journal: JCI Insight
Title: Neuron-specific PERK inactivation exacerbates neurodegeneration during experimental autoimmune encephalomyelitis.
Volume: 4
Issue: 2
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Publication
26960794 | J:312639
First Author: Fusakio ME
Year: 2016
Journal: Mol Biol Cell
Title: Transcription factor ATF4 directs basal and stress-induced gene expression in the unfolded protein response and cholesterol metabolism in the liver.
Volume: 27
Issue: 9
Pages: 1536-51
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Publication
21917591 | J:273445
First Author: Teske BF
Year: 2011
Journal: Mol Biol Cell
Title: The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress.
Volume: 22
Issue: 22
Pages: 4390-405
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Publication
22813743 | J:196023
First Author: Trinh MA
Year: 2012
Journal: Cell Rep
Title: Brain-specific disruption of the eIF2α kinase PERK decreases ATF4 expression and impairs behavioral flexibility.
Volume: 1
Issue: 6
Pages: 676-88
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Publication
15542627 | J:94221
First Author: Baltzis D
Year: 2004
Journal: J Virol
Title: Resistance to vesicular stomatitis virus infection requires a functional cross talk between the eukaryotic translation initiation factor 2alpha kinases PERK and PKR.
Volume: 78
Issue: 23
Pages: 12747-61
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Publication
21419175 | J:175009
First Author: Farmaki E
Year: 2011
Journal: Biochim Biophys Acta
Title: ERp29 regulates response to doxorubicin by a PERK-mediated mechanism.
Volume: 1813
Issue: 6
Pages: 1165-71
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Publication
28869608 | J:277868
First Author: Hong F
Year: 2017
Journal: Nat Struct Mol Biol
Title: CNPY2 is a key initiator of the PERK-CHOP pathway of the unfolded protein response.
Volume: 24
Issue: 10
Pages: 834-839
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Publication
17707796 | J:296095
First Author: Kondratyev M
Year: 2007
Journal: Exp Cell Res
Title: PERK-dependent compartmentalization of ERAD and unfolded protein response machineries during ER stress.
Volume: 313
Issue: 16
Pages: 3395-407
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Publication
18052927 | J:132301
First Author: Gomez E
Year: 2008
Journal: Biochem J
Title: A decrease in cellular energy status stimulates PERK-dependent eIF2alpha phosphorylation and regulates protein synthesis in pancreatic beta-cells.
Volume: 410
Issue: 3
Pages: 485-93
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Publication
23143306 | J:193979
First Author: Hart LS
Year: 2012
Journal: J Clin Invest
Title: ER stress-mediated autophagy promotes Myc-dependent transformation and tumor growth.
Volume: 122
Issue: 12
Pages: 4621-34
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Publication
24746698 | J:213604
First Author: Karali E
Year: 2014
Journal: Mol Cell
Title: VEGF Signals through ATF6 and PERK to promote endothelial cell survival and angiogenesis in the absence of ER stress.
Volume: 54
Issue: 4
Pages: 559-72
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Publication
27802424 | J:309341
First Author: Stone S
Year: 2016
Journal: Oncotarget
Title: Dual role of the integrated stress response in medulloblastoma tumorigenesis.
Volume: 7
Issue: 39
Pages: 64124-64135
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Publication
26039714 | J:319163
First Author: Li H
Year: 2015
Journal: Cell Cycle
Title: Administration of progranulin (PGRN) triggers ER stress and impairs insulin sensitivity via PERK-eIF2α-dependent manner.
Volume: 14
Issue: 12
Pages: 1893-907
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Publication
11106749 | J:99455
First Author: Harding HP
Year: 2000
Journal: Mol Cell
Title: Regulated translation initiation controls stress-induced gene expression in mammalian cells.
Volume: 6
Issue: 5
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