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Search results 201 to 292 out of 292 for Pomgnt1

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Type Details Score
GXD Expression
GXD Expression
     
Probe: MGI:5310263
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3557722
Stage: TS22
Assay Id: MGI:5423587
Age: embryonic day 14.5
Specimen Label: EH2499; Specimen C2962
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5310263
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1702122
Stage: TS22
Assay Id: MGI:5423587
Age: embryonic day 14.5
Specimen Label: EH2499; Specimen C2962
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5310263
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1756322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423587
Age: embryonic day 14.5
Image: EH2499; Specimen C2962
Specimen Label: EH2499; Specimen C2962
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5310263
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1668822
Stage: TS22
Assay Id: MGI:5423587
Age: embryonic day 14.5
Specimen Label: EH2499; Specimen C2962
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5310263
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Ubiquitous
Stage: TS22
Assay Id: MGI:5423587
Age: embryonic day 14.5
Image: EH2499; Specimen C2962
Specimen Label: EH2499; Specimen C2962
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5310263
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757522
Stage: TS22
Assay Id: MGI:5423587
Age: embryonic day 14.5
Specimen Label: EH2499; Specimen C2962
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5310263
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1738322
Stage: TS22
Assay Id: MGI:5423587
Age: embryonic day 14.5
Specimen Label: EH2499; Specimen C2962
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5310263
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1802422
Stage: TS22
Assay Id: MGI:5423587
Age: embryonic day 14.5
Specimen Label: EH2499; Specimen C2962
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6324625
Assay Type: RNA in situ
Annotation Date: 2019-07-26
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3521725
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6324913
Age: embryonic day 17.0
Note: Expression is in proliferating granule cell precursors.
Specimen Label: 1C
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5310263
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1768022
Stage: TS22
Assay Id: MGI:5423587
Age: embryonic day 14.5
Note: Expression was not detected in the skull (base and vault).
Specimen Label: EH2499; Specimen C2962
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5310263
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2672022
Stage: TS22
Assay Id: MGI:5423587
Age: embryonic day 14.5
Note: Expression was not detected in whisker follicle.
Specimen Label: EH2499; Specimen C2962
Detected: false
Specimen Num: 1
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Publication
25737452 | J:243934
First Author: Dwyer CA
Year: 2015
Journal: J Biol Chem
Title: Neurons and glia modify receptor protein-tyrosine phosphatase ζ (RPTPζ)/phosphacan with cell-specific O-mannosyl glycans in the developing brain.
Volume: 290
Issue: 16
Pages: 10256-73
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Publication
18490429 | J:137930
First Author: Lommel M
Year: 2008
Journal: Glycobiology
Title: POMT2, a key enzyme in Walker-Warburg syndrome: somatic sPOMT2, but not testis-specific tPOMT2, is crucial for mannosyltransferase activity in vivo.
Volume: 18
Issue: 8
Pages: 615-25
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Publication
32453729 | J:291123
First Author: Morioka S
Year: 2020
Journal: PLoS Genet
Title: Congenital hearing impairment associated with peripheral cochlear nerve dysmyelination in glycosylation-deficient muscular dystrophy.
Volume: 16
Issue: 5
Pages: e1008826
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Publication
22270369 | J:183288
First Author: Kuga A
Year: 2012
Journal: J Biol Chem
Title: Absence of post-phosphoryl modification in dystroglycanopathy mouse models and wild-type tissues expressing non-laminin binding form of α-dystroglycan.
Volume: 287
Issue: 12
Pages: 9560-7
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Publication
24256719 | J:215959
 
First Author: Yagi H
Year: 2013
Journal: Sci Rep
Title: AGO61-dependent GlcNAc modification primes the formation of functional glycans on α-dystroglycan.
Volume: 3
Pages: 3288
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Publication
23118208 | J:217719
First Author: Orr SL
Year: 2013
Journal: Glycobiology
Title: A phenotype survey of 36 mutant mouse strains with gene-targeted defects in glycosyltransferases or glycan-binding proteins.
Volume: 23
Issue: 3
Pages: 363-80
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Publication
20562862 | J:161922
First Author: Tang T
Year: 2010
Journal: Nat Biotechnol
Title: A mouse knockout library for secreted and transmembrane proteins.
Volume: 28
Issue: 7
Pages: 749-55
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Publication
- | J:94077
     
First Author: Mutant Mouse Regional Resource Centers
Year: 2004
Journal: Unpublished
Title: Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC)
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Publication
32290105 | J:282558
 
First Author: Collin GB
Year: 2020
Journal: Cells
Title: Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.
Volume: 9
Issue: 4
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Publication
- | J:171883
     
First Author: Lexicon Genetics, Inc
Year: 2011
Journal: Database Download
Title: MGI download of Lexicon knockout data
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein
Q91X88
Organism: Mus musculus/domesticus
Length: 660  
Fragment?: false
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Publication
26908613 | -
First Author: Xu M
Year: 2016
Journal: Hum Mol Genet
Title: Mutations in POMGNT1 cause non-syndromic retinitis pigmentosa.
Volume: 25
Issue: 8
Pages: 1479-88
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Protein
Q91X88-2
Organism: Mus musculus/domesticus
Length: 638  
Fragment?: false
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Protein
Q91X88-3
Organism: Mus musculus/domesticus
Length: 627  
Fragment?: false
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Publication
27493216 | -
First Author: Kuwabara N
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Carbohydrate-binding domain of the POMGnT1 stem region modulates O-mannosylation sites of α-dystroglycan.
Volume: 113
Issue: 33
Pages: 9280-5
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DO Term
DOID:0111236 | congenital muscular dystrophy-dystroglycanopathy type A3
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DO Term
DOID:0112378 | muscular dystrophy-dystroglycanopathy type B3
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Publication
16857188 | -
First Author: Abbott KL
Year: 2006
Journal: Exp Cell Res
Title: Integrin-dependent neuroblastoma cell adhesion and migration on laminin is regulated by expression levels of two enzymes in the O-mannosyl-linked glycosylation pathway, PomGnT1 and GnT-Vb.
Volume: 312
Issue: 15
Pages: 2837-50
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Protein
Q8K4R2
Organism: Mus musculus/domesticus
Length: 54  
Fragment?: false
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Protein Domain
IPR045587 | FKTN_N
Type: Domain
Description: This is the N-terminal domain of Ribitol-5-phosphate transferase FKTN (also referred to fukutin) which contains the transmembrane domain required for its localisation to the Golgi and participates in the interaction with POMGnT1 (Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1) for normal POMGnT1 location and activity []. FKTN is a ribitol-phosphate transferase that forms a complex with FKRP (fukutin-related protein, also a ribitol-phosphate transferase) and TMEM5 (a ribitol xylosyltransferase). Fukutin, FKRP, and TMEM5 maintain each of their enzyme activities in the complex and may contribute to specificbiosynthesis of glycans required for dystroglycan function [].
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Protein Domain
IPR039474 | POMGNT1_PANDER-like
Type: Domain
Description: O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) participates in O-mannosyl glycosylation and may be responsible for creating GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moieties on alpha dystroglycan and other O-mannosylated proteins [, ]. POMGnT1 consists of a stem domain, a catalytic domain, and an extended linker region connecting the two domains. The fold of the stem domain resembles that of PANDER (pancreatic-derived factor); a protein involved in the regulation of glucose homeostasis, but whose the molecular function has not been determined [].
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Protein
Q5M9P4
Organism: Mus musculus/domesticus
Length: 423  
Fragment?: true
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Publication
28751379 | -
First Author: Jansson AM
Year: 2017
Journal: J Biol Chem
Title: The interleukin-like epithelial-mesenchymal transition inducer ILEI exhibits a non-interleukin-like fold and is active as a domain-swapped dimer.
Volume: 292
Issue: 37
Pages: 15501-15511
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Protein Domain
IPR039477 | ILEI/PANDER_dom
Type: Domain
Description: This entry represents the ILEI/PANDER domain found in FAM3 family members and related proteins. Both PANDER and ILEI share a similar β-β-alpha fold, strikingly different from the classical cytokines [].FAM3C, also known as interleukin-like EMT inducer ILEI, is a secreted signaling protein involved in epithelial-mesenchymal transition and tumor progression [].FAM3B, also known as PANDER (PANcreatic DERived factor), is a cytokine-like protein that induces apoptosis of insulin-secreting beta-cells []and functions as a hormone by regulating glucose levels []. The fold of the stem domain of POMGnT1 (O-linked mannose beta1,2-N-acetylglucosaminyltransferase 1) resembles that of PANDER [].
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Protein
Q3UMQ5
Organism: Mus musculus/domesticus
Length: 385  
Fragment?: false
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Publication
23333428 | -
First Author: Johansson P
Year: 2013
Journal: Structure
Title: FAM3B PANDER and FAM3C ILEI represent a distinct class of signaling molecules with a non-cytokine-like fold.
Volume: 21
Issue: 2
Pages: 306-13
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Protein
Q8R507
Organism: Mus musculus/domesticus
Length: 461  
Fragment?: false
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Protein
A0A1Y7VM91
Organism: Mus musculus/domesticus
Length: 500  
Fragment?: false
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Publication
29477842 | -
First Author: Nishihara R
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Cell endogenous activities of fukutin and FKRP coexist with the ribitol xylosyltransferase, TMEM5.
Volume: 497
Issue: 4
Pages: 1025-1030
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Protein
Q9D309
Organism: Mus musculus/domesticus
Length: 235  
Fragment?: false
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Protein
A0A338P739
Organism: Mus musculus/domesticus
Length: 187  
Fragment?: false
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Protein
A0A338P693
Organism: Mus musculus/domesticus
Length: 246  
Fragment?: false
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Protein
A0A338P745
Organism: Mus musculus/domesticus
Length: 107  
Fragment?: false
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Publication
12941769 | -
First Author: Cao X
Year: 2003
Journal: Diabetes
Title: Pancreatic-derived factor (FAM3B), a novel islet cytokine, induces apoptosis of insulin-secreting beta-cells.
Volume: 52
Issue: 9
Pages: 2296-303
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Publication
21664909 | -
First Author: Wilson CG
Year: 2011
Journal: FEBS Lett
Title: PANcreatic-DERived factor: novel hormone PANDERing to glucose regulation.
Volume: 585
Issue: 14
Pages: 2137-43
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Publication
15614444 | J:173899
First Author: Yamamoto T
Year: 2004
Journal: Med Electron Microsc
Title: Expression and localization of fukutin, POMGnT1, and POMT1 in the central nervous system: consideration for functions of fukutin.
Volume: 37
Issue: 4
Pages: 200-7
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Protein
P97805
Organism: Mus musculus/domesticus
Length: 223  
Fragment?: false
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Protein
Q9D8T0
Organism: Mus musculus/domesticus
Length: 230  
Fragment?: false
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Protein
Q91VU0
Organism: Mus musculus/domesticus
Length: 227  
Fragment?: false
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Protein
I7HJS7
Organism: Mus musculus/domesticus
Length: 237  
Fragment?: false
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Protein
I7HLV5
Organism: Mus musculus/domesticus
Length: 199  
Fragment?: true
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Protein
Q6NSU0
Organism: Mus musculus/domesticus
Length: 303  
Fragment?: true
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Protein
A0A158SIT7
Organism: Mus musculus/domesticus
Length: 230  
Fragment?: false
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Protein
G5E911
Organism: Mus musculus/domesticus
Length: 247  
Fragment?: false
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Protein
G3X9I1
Organism: Mus musculus/domesticus
Length: 197  
Fragment?: false
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Protein
I7HPY1
Organism: Mus musculus/domesticus
Length: 192  
Fragment?: false
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Publication
11709191 | -
First Author: Yoshida A
Year: 2001
Journal: Dev Cell
Title: Muscular dystrophy and neuronal migration disorder caused by mutations in a glycosyltransferase, POMGnT1.
Volume: 1
Issue: 5
Pages: 717-24
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Protein
Q5FWI3
Organism: Mus musculus/domesticus
Length: 1383  
Fragment?: false
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Protein
Q8BI06
Organism: Mus musculus/domesticus
Length: 1361  
Fragment?: false
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Protein
Q14AX8
Organism: Mus musculus/domesticus
Length: 1361  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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