|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 201 to 214 out of 214 for Mapre2

<< First    < Previous  |  Next >    Last >>
0.017s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Publication
First Author: De Groot CO
Year: 2010
Journal: J Biol Chem
Title: Molecular insights into mammalian end-binding protein heterodimerization.
Volume: 285
Issue: 8
Pages: 5802-14
Publication
First Author: Liu H
Year: 2010
Journal: Mol Microbiol
Title: Aspergillus fumigatus AcuM regulates both iron acquisition and gluconeogenesis.
Volume: 78
Issue: 4
Pages: 1038-54
Publication
First Author: Geraldo S
Year: 2008
Journal: Nat Cell Biol
Title: Targeting of the F-actin-binding protein drebrin by the microtubule plus-tip protein EB3 is required for neuritogenesis.
Volume: 10
Issue: 10
Pages: 1181-9
Protein Domain
Type: Family
Description: This entry represents the microtubule-associated protein RP/EB (MAPRE) family, including MAPRE1 (EB1), MAPRE2 (RP1, also known as EB2), MAPRE3 (EBF3, also known as EB3) and their homologues from eukaryotes. Despite their high protein sequence conservation, the individual EBs exhibit different regulatory and functional properties []. For instance, EB1 and EB3, but not EB2, promote persistent microtubule growth by suppressing catastrophes [].EB1 contains an N-terminal calponin homology (CH) domain that is responsible for the interaction with microtubules (MTs), and a C-terminal coiled coil domain that extends into a four-helix bundle, required for dimer formation []. Through their C-terminal sequences, EBs interact with most other known +TIPs (plus end tracking proteins) and recruit many of them to the growing MT ends [, ]. EB1 is involved in MT anchoring at the centrosome and cell migration []. EB2 is highly expressed in pancreatic cancer cells, and seems to be involved in perineural invasion []. EB3 is specifically upregulated upon myogenic differentiation. Knockdown of EB3, but not that of EB1, prevents myoblast elongation and fusion into myotubes []. This entry also includes bZIP transcription factor hapX from the yeast Neosartorya fumigata, which is a transcription factor required for repression of genes during iron starvation [].
Protein
Organism: Mus musculus/domesticus
Length: 171  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 326  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 284  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 260  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 140  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 268  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 281  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 268  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 281  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 266  
Fragment?: false