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Search results 1301 to 1400 out of 1521 for Rb1

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Type Details Score
Genotype
Genotype
Symbol: Rb1/Rb1
Background: chimera involves: 129S2/SvPas * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1<+> Tg(Th-MYCN)41Waw/?
Background: involves: 129S2/SvPas * BALB/c * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1<+> Rbl1/Rbl1<+>
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1<+> Rbl1/Rbl1
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Tg(Rb1)1Blg/?
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Tg(Rb1)1Blg/?
Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1
Background: involves: 129S2/SvPas * 129S4/SvJae * BALB/c * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Tg(Rb1)1Blg/?
Background: involves: 129S2/SvPas
Zygosity: cx
Has Mutant Allele: true
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Strain
MGI:6827281 | FVB.129-Trp53<tm1Brn> Rb1<tm2Brn>/Nki
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:5607250 | STOCK Akap12<tm1Ihg> Rb1<tm2Brn> Tg(Pbsn-cre)4Prb/J
Attribute String: transgenic, targeted mutation, mutant stock
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Strain
MGI:5607255 | STOCK Rb1<tm2Brn>/J
Attribute String: targeted mutation, mutant stock
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Strain
MGI:3618505 | FVB;129-Rb1<tm2Brn>/Nci
Attribute String: targeted mutation, mutant stock
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Strain
MGI:4837358 | FVB.Cg-Rb1<tm2Brn> Tg(MMTV-cre)105Ayn
Attribute String: targeted mutation, transgenic, mutant strain, congenic
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Strain
MGI:3849042 | FVB;129P2-Rb1<tm2Brn>/Cnrm
Attribute String: targeted mutation, mutant stock
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Strain
MGI:4837360 | FVB.Cg-Trp53<tm1Brn> Rb1<tm2Brn> Tg(MMTV-cre)105Ayn
Attribute String: transgenic, targeted mutation, mutant strain, congenic
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Genotype
Genotype
Symbol: Rb1/Rb1 Trp53/Trp53<+> Tg(Rbp3-cre)1Brn/?
Background: involves: 129 * 129S7/SvEvBrd * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Tg(Rbp3-cre)1Brn/?
Background: involves: 129 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Tg(Col1a1-cre)1Bek/?
Background: involves: 129 * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Tg(Pou4f3-cre)1Devet/?
Background: involves: 129 * 129S/SvEv
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Tg(Pcp2-cre)756Mro/?
Background: involves: 129P2/OlaHsd * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1 Tg(Pcp2-cre)756Mro/?
Background: involves: 129P2/OlaHsd * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Tg(En2-cre)22Alj/?
Background: involves: 129P2/OlaHsd * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1 Tg(En2-cre)22Alj/?
Background: involves: 129P2/OlaHsd * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1<+> Tg(En2-cre)22Alj/?
Background: involves: 129P2/OlaHsd * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1<+> Trp53/Trp53 Tg(En2-cre)22Alj/?
Background: involves: 129P2/OlaHsd * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Tg(Myh6-cre)2182Mds/Tg(Myh6-cre)2182Mds
Background: involves: 129 * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl2/Rbl2 Tg(Myh6-cre)2182Mds/Tg(Myh6-cre)2182Mds
Background: involves: 129 * 129S2/SvPas * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Trp53/Trp53 Tg(Gfap-cre)2Brn/?
Background: involves: 129 * 129S7/SvEvBrd * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Trp53/Trp53 Tg(Gfap-cre)2Brn/?
Background: involves: 129P2/OlaHsd * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Tg(Gfap-cre)2Brn/?
Background: involves: 129 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Tg(KRT14-cre)8Brn/? Tg(KRT5-Akt1*)Jmpa/?
Background: involves: 129 * C57BL/6 * DBA/2 * DBA/2J * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1
Background: involves: 129 * BALB/c
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Trp53/Trp53
Background: involves: 129P2/OlaHsd
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Trp53/Trp53<+>
Background: involves: 129P2/OlaHsd
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1
Background: involves: 129
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Tg(MMTV-cre)105Ayn/?
Background: FVB.Cg-Rb1 Tg(MMTV-cre)105Ayn
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Trp53/Trp53 Tg(MMTV-cre)105Ayn/?
Background: FVB.Cg-Trp53 Rb1 Tg(MMTV-cre)105Ayn
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Rb1/Rb1 Tg(Gfap-cre)2Brn/?
Background: either: (involves: 129 * 129P2/OlaHsd * FVB/N) or (involves: 129 * 129P2/OlaHsd * C57BL/6 * FVB/N)
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Rb1/Rb1 Trp53/Trp53 Tg(Gfap-cre)2Brn/?
Background: either: (involves: 129 * 129P2/OlaHsd * FVB/N) or (involves: 129 * 129P2/OlaHsd * C57BL/6 * FVB/N)
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Trp53/Trp53 Tg(Gfap-cre)2Brn/?
Background: involves: 129 * 129P2/OlaHsd * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Trp53/Trp53
Background: involves: 129
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Calca/Calca<+> Trp53/Trp53 Rb1/Rb1
Background: involves: 129 * 129P2/OlaHsd * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ccnd3/Ccnd3 Rb1/Rb1 Tg(Mx1-cre)1Cgn/?
Background: involves: 129 * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ccnd3/Ccnd3 Cdkn1b/Cdkn1b Rb1/Rb1 Tg(Mx1-cre)1Cgn/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor Rb1/Rb1 Trp53/Trp53
Background: involves: 129 * 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor Pten/Pten Rb1/Rb1
Background: involves: 129 * 129S4/SvJaeSor * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor Pten/Pten Rb1/Rb1 Trp53/Trp53
Background: involves: 129 * 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Tg(Cyp1a1-cre)1Dwi/?
Background: involves: 129 * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Trp53/Trp53 Tg(Ren-cre)#Kwg/?
Background: involves: 129 * 129P2/OlaHsd
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1<+> Trp53/Trp53
Background: involves: 129P2/OlaHsd
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1 Rbl2/Rbl2
Background: involves: 129 * 129S2/SvPas * 129S4/SvJae
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Trp53/Trp53 Tg(Col1a1-cre)1Kry/?
Background: involves: 129 * 129P2/OlaHsd * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1<+> Trp53/Trp53 Tg(Col1a1-cre)1Kry/?
Background: involves: 129 * 129P2/OlaHsd * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prkar1a/Prkar1a<+> Rb1/Rb1<+> Tg(Col1a1-cre)1Kry/? Trp53/Trp53
Background: involves: 129 * 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prkar1a/Prkar1a<+> Rb1/Rb1 Trp53/Trp53 Tg(Col1a1-cre)1Kry/?
Background: involves: 129 * 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Dlg2/Dlg2 Rb1/Rb1 Trp53/Trp53 Tg(Col1a1-cre)1Kry/?
Background: involves: 129 * 129P2/OlaHsd * C57BL/6N * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Trp53/Trp53 Tg(KRT14-cre)8Brn/?
Background: involves: 129 * 129P2/OlaHsd * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Tg(KRT14-cre)8Brn/?
Background: involves: 129 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1
Background: involves: 129 * FVB/N
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1 Tg(KRT14-cre)8Brn/?
Background: involves: 129 * 129S2/SvPas * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Plekha5/Plekha5<+>
Background: involves: 129 * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1<+> Plekha5/Plekha5<+>
Background: involves: 129 * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Tg(Pou4f3-cre)1Devet/?
Background: involves: 129
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1<+> Tg(Pou4f3-cre)1Devet/?
Background: involves: 129
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Trp53/Trp53 Tg(Pbsn-cre)4Prb/?
Background: involves: 129 * 129P2/OlaHsd * C57BL/6 * DBA/2 * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Trp53/Trp53 Tg(Pbsn-cre)4Prb/?
Background: involves: 129 * 129P2/OlaHsd * C57BL/6 * DBA/2 * FVB
Zygosity: cn
Has Mutant Allele: true
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Publication
1835093 | -
First Author: Webster LC
Year: 1991
Journal: Proc Natl Acad Sci U S A
Title: Conversion of the E1A Cys4 zinc finger to a nonfunctional His2,Cys2 zinc finger by a single point mutation.
Volume: 88
Issue: 22
Pages: 9989-93
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Publication
1316611 | -
First Author: Chellappan S
Year: 1992
Journal: Proc Natl Acad Sci U S A
Title: Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product.
Volume: 89
Issue: 10
Pages: 4549-53
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Publication
22718244 | -
First Author: Bellacchio E
Year: 2013
Journal: J Cell Physiol
Title: Understanding the targeting of the RB family proteins by viral oncoproteins to defeat their oncogenic machinery.
Volume: 228
Issue: 2
Pages: 285-91
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Protein Domain
IPR014410 | Aden_E1A
Type: Family
Description: This group represents adenoviral early E1A proteins. The E1A protein is responsible for the transcriptional activation of the early genes with in the viral genome at the start of the infection process as well as some cellular genes [].E1A disrupts the function of host retinoblastoma protein RB1/pRb, which is a key regulator of the cell cycle []. It also induces the disassembly of the E2F1 transcription factors from RB1 by direct competition for the same binding site on RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes []. Inactivation of the ability of RB1 to arrest the cell cycle is critical for cellular transformation, uncontrolled cellular growth and proliferation induced by viral infection. The stimulation of the progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication.
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Publication
20404145 | J:160331
First Author: Kujuro Y
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Esophageal cancer-related gene 4 is a secreted inducer of cell senescence expressed by aged CNS precursor cells.
Volume: 107
Issue: 18
Pages: 8259-64
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Protein
Q99LS0
Organism: Mus musculus/domesticus
Length: 148  
Fragment?: false
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Publication
12800218 | -
First Author: Yue CM
Year: 2003
Journal: World J Gastroenterol
Title: Expression of ECRG4, a novel esophageal cancer-related gene, downregulated by CpG island hypermethylation in human esophageal squamous cell carcinoma.
Volume: 9
Issue: 6
Pages: 1174-8
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Publication
20233222 | -
First Author: Tadross JA
Year: 2010
Journal: Br J Pharmacol
Title: Augurin stimulates the hypothalamo-pituitary-adrenal axis via the release of corticotrophin-releasing factor in rats.
Volume: 159
Issue: 8
Pages: 1663-71
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Protein Domain
IPR028173 | Augurin
Type: Family
Description: Augurin is alternatively named oesophageal cancer-related gene 4 protein. The function of this family of transmembrane proteins is to induce the senescence of oligodendrocyte and neural precursor cells, characterised by G1 arrest, RB1 dephosphorylation and accelerated CCND1 and CCND3 proteasomal degradation [, ]. Augurin is a posible hormone that has been found to stimulate the release of adrenocorticotropic hormone (ACTH) via the release of hypothalamic corticotrophin-releasing factor (CRF) [].
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Genotype
Genotype
Symbol: E2f1/E2f1 Rb1/Rb1 Tg(Rb1)1Blg/?
Background: involves: 129S2/SvPas * 129S4/SvJae
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdkn1a/Cdkn1a Rb1/Rb1 Tg(Rb1)1Blg/?
Background: involves: 129S2/SvPas
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdkn1a/Cdkn1a Rb1/Rb1<+> Tg(Rb1)1Blg/?
Background: involves: 129S2/SvPas
Zygosity: cx
Has Mutant Allele: true
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Publication
21397851 | J:169932
First Author: Maire CL
Year: 2011
Journal: Cancer Cell
Title: Glioma models: new GEMMs add "class" with genomic and expression correlations.
Volume: 19
Issue: 3
Pages: 295-7
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Allele
Tg(LPV-TAg121*E107K)3Tvd | MGI:3531489
Name: transgene insertion 3, Terry Van Dyke
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(LPV-TAg121*E107K)4Tvd | MGI:3531490
Name: transgene insertion 4, Terry Van Dyke
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Publication
22182413 | J:180294
First Author: Wang B
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Liver tumor formation by a mutant retinoblastoma protein in the transgenic mice is caused by an upregulation of c-Myc target genes.
Volume: 417
Issue: 1
Pages: 601-6
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Allele
Tg(LPV-TAg121*E107K)#Tvd | MGI:3531488
Name: transgene insertion #, Terry Van Dyke
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(LPV-TAg121*E107K)5Tvd | MGI:3531491
Name: transgene insertion 5, Terry Van Dyke
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:6144448 | B6D2-Tg(WAPT121)66Tvd/Nci
Attribute String: mutant stock, transgenic
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Genotype
Genotype
Symbol: Rb1/Rb1
Background: either: 129P2/OlaHsd-Rb1 or (involves: 129P2/OlaHsd * BALB/c) or (involves: 129P2/OlaHsd * FVB/N)
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1
Background: either: 129P2/OlaHsd-Rb1 or (involves: 129P2/OlaHsd * BALB/c) or (involves: 129P2/OlaHsd * FVB/N)
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1<+>
Background: either: 129P2/OlaHsd-Rb1 or (involves: 129P2/OlaHsd * BALB/c) or (involves: 129P2/OlaHsd * FVB/N)
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1<+>
Background: either: 129P2/OlaHsd-Rb1 or (involves: 129P2/OlaHsd * BALB/c) or (involves: 129P2/OlaHsd * FVB/N)
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Hnf1a-RB1*)XMiu/?
Background: Not Specified
Zygosity: ot
Has Mutant Allele: true
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Publication
25755634 | J:242452
 
First Author: Tarang S
Year: 2015
Journal: Front Cell Neurosci
Title: Generation of a Retinoblastoma (Rb)1-inducible dominant-negative (DN) mouse model.
Volume: 9
Pages: 52
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Genotype
Genotype
Symbol: Apaf1/Apaf1 Rb1/Rb1 Tg(Rb1)1Blg/?
Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Tg(Rb1)1Blg/? Trp53/Trp53
Background: involves: 129S2/SvPas
Zygosity: cx
Has Mutant Allele: true
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Publication
1395722 | J:2899
First Author: Lemieux N
Year: 1992
Journal: Cytogenet Cell Genet
Title: New gene assignments to rabbit chromosomes; implications for chromosome evolution.
Volume: 61
Issue: 2
Pages: 132-4
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Genotype
Genotype
Symbol: Calca/Calca<+> Trp53/Trp53 Rb1/Rb1 Pten/Pten
Background: involves: 129 * 129P2/OlaHsd * 129S4/SvJae * BALB/c * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nell1/Nell1 Rb1/Rb1 Trp53/Trp53 Tg(BGLAP-cre)1Clem/?
Background: involves: 129 * FVB/NJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Trp53/Trp53 Tg(BGLAP-cre)1Clem/?
Background: involves: 129 * 129P2/OlaHsd * FVB/NJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Rb1/Rb1 Tg(Prdm1-cre)1Masu/?
Background: involves: C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Publication
14966529 | J:88315
First Author: Simin K
Year: 2004
Journal: PLoS Biol
Title: pRb inactivation in mammary cells reveals common mechanisms for tumor initiation and progression in divergent epithelia.
Volume: 2
Issue: 2
Pages: E22
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