This protein family includes Protein FAM210A (and its homologues) and FAM210B, which contain a transmembrane peptide [, , ].FAM210A, a protein essential in maintaining skeletal muscle structure and strength [], interacts with mitochondrial translation elongation factor EF-Tu and promotes mitochondrial protein expression. FAM210B plays a role in erythroid differentiation and is involved in cell proliferation and tumor cell growth suppression [, ].
This domain is found in mitochondrial proteins, including FAM210A (and its homologues) and B, which contain a transmembrane peptide [, , ]. Its function is not clear. FAM210A, a protein essential in maintaining skeletal muscle structure and strength [], interacts with mitochondrial translation elongation factor EF-Tu and promotes mitochondrial protein expression. In FAM210A, this domain is responsible for binding EF-Tu []. FAM210B plays a role in erythroid differentiation and is involved in cell proliferation and tumor cell growth suppression [, ]. This domain is also present in the uncharacterised protein C106.07c from fission yeast and putative N-terminal acetyltransferase 2 from Baker's yeast.
