Type |
Details |
Score |
Publication |
First Author: |
Liebmann T |
Year: |
2016 |
Journal: |
Cell Rep |
Title: |
Three-Dimensional Study of Alzheimer's Disease Hallmarks Using the iDISCO Clearing Method. |
Volume: |
16 |
Issue: |
4 |
Pages: |
1138-1152 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lardenoije R |
Year: |
2018 |
Journal: |
Mol Cell Neurosci |
Title: |
Age-related epigenetic changes in hippocampal subregions of four animal models of Alzheimer's disease. |
Volume: |
86 |
|
Pages: |
1-15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jadiya P |
Year: |
2019 |
Journal: |
Nat Commun |
Title: |
Impaired mitochondrial calcium efflux contributes to disease progression in models of Alzheimer's disease. |
Volume: |
10 |
Issue: |
1 |
Pages: |
3885 |
|
•
•
•
•
•
|
Publication |
First Author: |
Clarke JR |
Year: |
2015 |
Journal: |
EMBO Mol Med |
Title: |
Alzheimer-associated Aβ oligomers impact the central nervous system to induce peripheral metabolic deregulation. |
Volume: |
7 |
Issue: |
2 |
Pages: |
190-210 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kamphuis W |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
GFAP isoforms in adult mouse brain with a focus on neurogenic astrocytes and reactive astrogliosis in mouse models of Alzheimer disease. |
Volume: |
7 |
Issue: |
8 |
Pages: |
e42823 |
|
•
•
•
•
•
|
Publication |
First Author: |
Roy DS |
Year: |
2016 |
Journal: |
Nature |
Title: |
Memory retrieval by activating engram cells in mouse models of early Alzheimer's disease. |
Volume: |
531 |
Issue: |
7595 |
Pages: |
508-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jiang H |
Year: |
2020 |
Journal: |
Sci Rep |
Title: |
Live Neuron High-Content Screening Reveals Synaptotoxic Activity in Alzheimer Mouse Model Homogenates. |
Volume: |
10 |
Issue: |
1 |
Pages: |
3412 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lacomme M |
Year: |
2022 |
Journal: |
Sci Adv |
Title: |
Numb regulates Tau levels and prevents neurodegeneration in tauopathy mouse models. |
Volume: |
8 |
Issue: |
42 |
Pages: |
eabm4295 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhou Q |
Year: |
2022 |
Journal: |
EBioMedicine |
Title: |
Human tau accumulation promotes glycogen synthase kinase-3β acetylation and thus upregulates the kinase: A vicious cycle in Alzheimer neurodegeneration. |
Volume: |
78 |
|
Pages: |
103970 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hamilton A |
Year: |
2016 |
Journal: |
Cell Rep |
Title: |
Chronic Pharmacological mGluR5 Inhibition Prevents Cognitive Impairment and Reduces Pathogenesis in an Alzheimer Disease Mouse Model. |
Volume: |
15 |
Issue: |
9 |
Pages: |
1859-65 |
|
•
•
•
•
•
|
Publication |
First Author: |
Haas LT |
Year: |
2017 |
Journal: |
Cell Rep |
Title: |
Silent Allosteric Modulation of mGluR5 Maintains Glutamate Signaling while Rescuing Alzheimer's Mouse Phenotypes. |
Volume: |
20 |
Issue: |
1 |
Pages: |
76-88 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chow HM |
Year: |
2014 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
CDK5 activator protein p25 preferentially binds and activates GSK3β. |
Volume: |
111 |
Issue: |
45 |
Pages: |
E4887-95 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen M |
Year: |
2021 |
Journal: |
Mol Neurodegener |
Title: |
Enhancing GABAergic signaling ameliorates aberrant gamma oscillations of olfactory bulb in AD mouse models. |
Volume: |
16 |
Issue: |
1 |
Pages: |
14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ben Haim L |
Year: |
2015 |
Journal: |
J Neurosci |
Title: |
The JAK/STAT3 pathway is a common inducer of astrocyte reactivity in Alzheimer's and Huntington's diseases. |
Volume: |
35 |
Issue: |
6 |
Pages: |
2817-29 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu L |
Year: |
2021 |
Journal: |
Aging Cell |
Title: |
Therapeutic efficacy of novel memantine nitrate MN-08 in animal models of Alzheimer's disease. |
Volume: |
20 |
Issue: |
6 |
Pages: |
e13371 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fang EF |
Year: |
2019 |
Journal: |
Nat Neurosci |
Title: |
Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease. |
Volume: |
22 |
Issue: |
3 |
Pages: |
401-412 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jan A |
Year: |
2017 |
Journal: |
Acta Neuropathol |
Title: |
eEF2K inhibition blocks Aβ42 neurotoxicity by promoting an NRF2 antioxidant response. |
Volume: |
133 |
Issue: |
1 |
Pages: |
101-119 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wei Y |
Year: |
2018 |
Journal: |
Cell Death Dis |
Title: |
Oxidation of KCNB1 channels in the human brain and in mouse model of Alzheimer's disease. |
Volume: |
9 |
Issue: |
8 |
Pages: |
820 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu H |
Year: |
2023 |
Journal: |
PLoS Biol |
Title: |
DSCAM gene triplication causes excessive GABAergic synapses in the neocortex in Down syndrome mouse models. |
Volume: |
21 |
Issue: |
4 |
Pages: |
e3002078 |
|
•
•
•
•
•
|
Publication |
First Author: |
Adorno M |
Year: |
2018 |
Journal: |
Sci Rep |
Title: |
Usp16 modulates Wnt signaling in primary tissues through Cdkn2a regulation. |
Volume: |
8 |
Issue: |
1 |
Pages: |
17506 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang L |
Year: |
2012 |
Journal: |
Bioeng Bugs |
Title: |
Genetic analysis of Down syndrome facilitated by mouse chromosome engineering. |
Volume: |
3 |
Issue: |
1 |
Pages: |
8-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gupta M |
Year: |
2016 |
Journal: |
Mamm Genome |
Title: |
Mouse models of Down syndrome: gene content and consequences. |
Volume: |
27 |
Issue: |
11-12 |
Pages: |
538-555 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sheppard K |
Year: |
2022 |
Journal: |
Cell Rep |
Title: |
Stride-level analysis of mouse open field behavior using deep-learning-based pose estimation. |
Volume: |
38 |
Issue: |
2 |
Pages: |
110231 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gao FJ |
Year: |
2021 |
Journal: |
Acta Neuropathol Commun |
Title: |
Forebrain Shh overexpression improves cognitive function and locomotor hyperactivity in an aneuploid mouse model of Down syndrome and its euploid littermates. |
Volume: |
9 |
Issue: |
1 |
Pages: |
137 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lian H |
Year: |
2016 |
Journal: |
J Neurosci |
Title: |
Astrocyte-Microglia Cross Talk through Complement Activation Modulates Amyloid Pathology in Mouse Models of Alzheimer's Disease. |
Volume: |
36 |
Issue: |
2 |
Pages: |
577-89 |
|
•
•
•
•
•
|
Publication |
First Author: |
Maeda S |
Year: |
2016 |
Journal: |
EMBO Rep |
Title: |
Expression of A152T human tau causes age-dependent neuronal dysfunction and loss in transgenic mice. |
Volume: |
17 |
Issue: |
4 |
Pages: |
530-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Palop JJ |
Year: |
2007 |
Journal: |
Neuron |
Title: |
Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease. |
Volume: |
55 |
Issue: |
5 |
Pages: |
697-711 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hall AM |
Year: |
2015 |
Journal: |
J Neurosci |
Title: |
Tau-dependent Kv4.2 depletion and dendritic hyperexcitability in a mouse model of Alzheimer's disease. |
Volume: |
35 |
Issue: |
15 |
Pages: |
6221-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Roberson ED |
Year: |
2011 |
Journal: |
J Neurosci |
Title: |
Amyloid-β/Fyn-induced synaptic, network, and cognitive impairments depend on tau levels in multiple mouse models of Alzheimer's disease. |
Volume: |
31 |
Issue: |
2 |
Pages: |
700-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Savas JN |
Year: |
2017 |
Journal: |
Cell Rep |
Title: |
Amyloid Accumulation Drives Proteome-wide Alterations in Mouse Models of Alzheimer's Disease-like Pathology. |
Volume: |
21 |
Issue: |
9 |
Pages: |
2614-2627 |
|
•
•
•
•
•
|
Publication |
First Author: |
Melnikova T |
Year: |
2006 |
Journal: |
Neuroscience |
Title: |
Cycloxygenase-2 activity promotes cognitive deficits but not increased amyloid burden in a model of Alzheimer's disease in a sex-dimorphic pattern. |
Volume: |
141 |
Issue: |
3 |
Pages: |
1149-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Watts JC |
Year: |
2011 |
Journal: |
PLoS Pathog |
Title: |
Protease-resistant prions selectively decrease Shadoo protein. |
Volume: |
7 |
Issue: |
11 |
Pages: |
e1002382 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
655
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Allele |
Name: |
low density lipoprotein receptor; targeted mutation 1, Joachim Herz |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
colony stimulating factor 1 (macrophage); osteopetrosis |
Allele Type: |
Spontaneous |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Nakatsu F |
Year: |
1999 |
Journal: |
Cytogenet Cell Genet |
Title: |
Genomic structure and chromosome mapping of the genes encoding clathrin-associated adaptor medium chains mu1A (Ap1m1) and mu1B (Ap1m2). |
Volume: |
87 |
Issue: |
1-2 |
Pages: |
53-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kerr SM |
Year: |
1994 |
Journal: |
Mamm Genome |
Title: |
Analysis of cDNA sequences from mouse testis. |
Volume: |
5 |
Issue: |
9 |
Pages: |
557-65 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
920
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
900
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
920
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
65
|
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Cascella M |
Year: |
2005 |
Journal: |
J Am Chem Soc |
Title: |
Evolutionarily conserved functional mechanics across pepsin-like and retroviral aspartic proteases. |
Volume: |
127 |
Issue: |
11 |
Pages: |
3734-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Revuelta MV |
Year: |
2014 |
Journal: |
Genome Biol Evol |
Title: |
Extensive expansion of A1 family aspartic proteinases in fungi revealed by evolutionary analyses of 107 complete eukaryotic proteomes. |
Volume: |
6 |
Issue: |
6 |
Pages: |
1480-94 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ishii M |
Year: |
2015 |
Journal: |
Cell Metab |
Title: |
Metabolic and Non-Cognitive Manifestations of Alzheimer's Disease: The Hypothalamus as Both Culprit and Target of Pathology. |
Volume: |
22 |
Issue: |
5 |
Pages: |
761-76 |
|
•
•
•
•
•
|
Publication |
First Author: |
RodrÃguez JJ |
Year: |
2009 |
Journal: |
Cell Death Differ |
Title: |
Astroglia in dementia and Alzheimer's disease. |
Volume: |
16 |
Issue: |
3 |
Pages: |
378-85 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kumar S |
Year: |
2020 |
Journal: |
Acta Neuropathol Commun |
Title: |
Phosphorylated Aβ peptides in human Down syndrome brain and different Alzheimer's-like mouse models. |
Volume: |
8 |
Issue: |
1 |
Pages: |
118 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dudeffant C |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
Contrast-enhanced MR microscopy of amyloid plaques in five mouse models of amyloidosis and in human Alzheimer's disease brains. |
Volume: |
7 |
Issue: |
1 |
Pages: |
4955 |
|
•
•
•
•
•
|
Publication |
First Author: |
Roubertoux PL |
Year: |
2017 |
Journal: |
Behav Genet |
Title: |
Differential Brain, Cognitive and Motor Profiles Associated with Partial Trisomy. Modeling Down Syndrome in Mice. |
Volume: |
47 |
Issue: |
3 |
Pages: |
305-322 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hashimoto M |
Year: |
2003 |
Journal: |
Ann N Y Acad Sci |
Title: |
Transgenic models of alpha-synuclein pathology: past, present, and future. |
Volume: |
991 |
|
Pages: |
171-88 |
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•
•
•
•
•
|
Publication |
First Author: |
Pozueta J |
Year: |
2013 |
Journal: |
Neuroscience |
Title: |
Synaptic changes in Alzheimer's disease and its models. |
Volume: |
251 |
|
Pages: |
51-65 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Szecsi PB |
Year: |
1992 |
Journal: |
Scand J Clin Lab Invest Suppl |
Title: |
The aspartic proteases. |
Volume: |
210 |
|
Pages: |
5-22 |
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•
•
•
•
•
|
Publication |
First Author: |
Inoue S |
Year: |
2000 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Growth suppression of Escherichia coli by induction of expression of mammalian genes with transmembrane or ATPase domains. |
Volume: |
268 |
Issue: |
2 |
Pages: |
553-61 |
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•
•
•
•
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Publication |
First Author: |
Frake RA |
Year: |
2015 |
Journal: |
J Clin Invest |
Title: |
Autophagy and neurodegeneration. |
Volume: |
125 |
Issue: |
1 |
Pages: |
65-74 |
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•
•
•
•
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Publication |
First Author: |
Paris D |
Year: |
1995 |
Journal: |
Mouse Genome |
Title: |
A comparison between and inbred strain and hybrid lines to generate transgenic mice. |
Volume: |
93 |
Issue: |
4 |
Pages: |
1038-40 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Allele |
Name: |
caveolin 1, caveolae protein; targeted mutation 1, Michael P Lisanti |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen H |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
Identification of novel markers of mouse fetal ovary development. |
Volume: |
7 |
Issue: |
7 |
Pages: |
e41683 |
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•
•
•
•
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Publication |
First Author: |
Ye A |
Year: |
2016 |
Journal: |
Epigenetics |
Title: |
PEG3 binds to H19-ICR as a transcriptional repressor. |
Volume: |
11 |
Issue: |
12 |
Pages: |
889-900 |
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•
•
•
•
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Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
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•
•
•
•
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Publication |
First Author: |
Naismith JH |
Year: |
1998 |
Journal: |
Trends Biochem Sci |
Title: |
Modularity in the TNF-receptor family. |
Volume: |
23 |
Issue: |
2 |
Pages: |
74-9 |
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•
•
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Publication |
First Author: |
Bodmer JL |
Year: |
2002 |
Journal: |
Trends Biochem Sci |
Title: |
The molecular architecture of the TNF superfamily. |
Volume: |
27 |
Issue: |
1 |
Pages: |
19-26 |
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•
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•
•
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Publication |
First Author: |
Hansen J |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. |
Volume: |
100 |
Issue: |
17 |
Pages: |
9918-22 |
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•
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•
•
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Publication |
First Author: |
Davies DR |
Year: |
1990 |
Journal: |
Annu Rev Biophys Biophys Chem |
Title: |
The structure and function of the aspartic proteinases. |
Volume: |
19 |
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Pages: |
189-215 |
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•
•
•
•
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Publication |
First Author: |
Rao JK |
Year: |
1991 |
Journal: |
Biochemistry |
Title: |
Structural and evolutionary relationships between retroviral and eucaryotic aspartic proteinases. |
Volume: |
30 |
Issue: |
19 |
Pages: |
4663-71 |
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•
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•
•
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Publication |
First Author: |
Foltmann B |
Year: |
1981 |
Journal: |
Essays Biochem |
Title: |
Gastric proteinases--structure, function, evolution and mechanism of action. |
Volume: |
17 |
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Pages: |
52-84 |
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Publication |
First Author: |
Ko MS |
Year: |
2000 |
Journal: |
Development |
Title: |
Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. |
Volume: |
127 |
Issue: |
8 |
Pages: |
1737-49 |
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•
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Publication |
First Author: |
Krawchuk D |
Year: |
2015 |
Journal: |
J Cell Sci |
Title: |
Loss of LKB1 leads to impaired epithelial integrity and cell extrusion in the early mouse embryo. |
Volume: |
128 |
Issue: |
5 |
Pages: |
1011-22 |
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•
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Publication |
First Author: |
Angueira AR |
Year: |
2021 |
Journal: |
Nat Metab |
Title: |
Defining the lineage of thermogenic perivascular adipose tissue. |
Volume: |
3 |
Issue: |
4 |
Pages: |
469-484 |
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•
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Publication |
First Author: |
Pletcher MT |
Year: |
2001 |
Journal: |
Genomics |
Title: |
Use of comparative physical and sequence mapping to annotate mouse chromosome 16 and human chromosome 21. |
Volume: |
74 |
Issue: |
1 |
Pages: |
45-54 |
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•
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Publication |
First Author: |
Helmholtz Zentrum Muenchen GmbH |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
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•
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Publication |
First Author: |
Li H |
Year: |
2006 |
Journal: |
Mol Cell Neurosci |
Title: |
Potential target genes of EMX2 include Odz/Ten-M and other gene families with implications for cortical patterning. |
Volume: |
33 |
Issue: |
2 |
Pages: |
136-49 |
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Publication |
First Author: |
Fletcher CF |
Year: |
1997 |
Journal: |
Genomics |
Title: |
Mouse chromosomal locations of nine genes encoding homologs of human paraneoplastic neurologic disorder antigens. |
Volume: |
45 |
Issue: |
2 |
Pages: |
313-9 |
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•
•
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Publication |
First Author: |
Brunskill EW |
Year: |
2008 |
Journal: |
Dev Cell |
Title: |
Atlas of gene expression in the developing kidney at microanatomic resolution. |
Volume: |
15 |
Issue: |
5 |
Pages: |
781-91 |
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