Type |
Details |
Score |
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Contreras PS |
Year: |
2020 |
Journal: |
iScience |
Title: |
c-Abl Inhibition Activates TFEB and Promotes Cellular Clearance in a Lysosomal Disorder. |
Volume: |
23 |
Issue: |
11 |
Pages: |
101691 |
|
•
•
•
•
•
|
Publication |
First Author: |
Magini A |
Year: |
2017 |
Journal: |
Hum Mol Genet |
Title: |
TFEB activation restores migration ability to Tsc1-deficient adult neural stem/progenitor cells. |
Volume: |
26 |
Issue: |
17 |
Pages: |
3303-3312 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang J |
Year: |
2019 |
Journal: |
Autophagy |
Title: |
Cross-regulation of defective endolysosome trafficking and enhanced autophagy through TFEB in UNC13D deficiency. |
Volume: |
15 |
Issue: |
10 |
Pages: |
1738-1756 |
|
•
•
•
•
•
|
Publication |
First Author: |
Arhzaouy K |
Year: |
2019 |
Journal: |
Autophagy |
Title: |
VCP maintains lysosomal homeostasis and TFEB activity in differentiated skeletal muscle. |
Volume: |
15 |
Issue: |
6 |
Pages: |
1082-1099 |
|
•
•
•
•
•
|
Publication |
First Author: |
Palmieri M |
Year: |
2017 |
Journal: |
Nat Commun |
Title: |
mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases. |
Volume: |
8 |
|
Pages: |
14338 |
|
•
•
•
•
•
|
Publication |
First Author: |
Trivedi PC |
Year: |
2016 |
Journal: |
Biochim Biophys Acta |
Title: |
Glucolipotoxicity diminishes cardiomyocyte TFEB and inhibits lysosomal autophagy during obesity and diabetes. |
Volume: |
1861 |
Issue: |
12 Pt A |
Pages: |
1893-1910 |
|
•
•
•
•
•
|
Publication |
First Author: |
Matthews I |
Year: |
2023 |
Journal: |
Cell Rep |
Title: |
Skeletal muscle TFEB signaling promotes central nervous system function and reduces neuroinflammation during aging and neurodegenerative disease. |
Volume: |
42 |
Issue: |
11 |
Pages: |
113436 |
|
•
•
•
•
•
|
Publication |
First Author: |
El-Houjeiri L |
Year: |
2019 |
Journal: |
Cell Rep |
Title: |
The Transcription Factors TFEB and TFE3 Link the FLCN-AMPK Signaling Axis to Innate Immune Response and Pathogen Resistance. |
Volume: |
26 |
Issue: |
13 |
Pages: |
3613-3628.e6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xia Q |
Year: |
2016 |
Journal: |
EMBO J |
Title: |
TDP-43 loss of function increases TFEB activity and blocks autophagosome-lysosome fusion. |
Volume: |
35 |
Issue: |
2 |
Pages: |
121-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Comerota MM |
Year: |
2023 |
Journal: |
Mol Neurodegener |
Title: |
Oleoylethanolamide facilitates PPARα and TFEB signaling and attenuates Aβ pathology in a mouse model of Alzheimer's disease. |
Volume: |
18 |
Issue: |
1 |
Pages: |
56 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang H |
Year: |
2016 |
Journal: |
eNeuro |
Title: |
TFEB Overexpression in the P301S Model of Tauopathy Mitigates Increased PHF1 Levels and Lipofuscin Puncta and Rescues Memory Deficits. |
Volume: |
3 |
Issue: |
2 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Nabar NR |
Year: |
2022 |
Journal: |
Autophagy |
Title: |
LRRK2 is required for CD38-mediated NAADP-Ca2+ signaling and the downstream activation of TFEB (transcription factor EB) in immune cells. |
Volume: |
18 |
Issue: |
1 |
Pages: |
204-222 |
|
•
•
•
•
•
|
Allele |
Name: |
transcription factor EB; endonuclease-mediated mutation 2, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Allele |
Name: |
transcription factor EB; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhao GQ |
Year: |
1993 |
Journal: |
Mol Cell Biol |
Title: |
TFEC, a basic helix-loop-helix protein, forms heterodimers with TFE3 and inhibits TFE3-dependent transcription activation. |
Volume: |
13 |
Issue: |
8 |
Pages: |
4505-12 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
32
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This entry represents a domain found at the N terminus of the MiT/TFE family members, which include MITF (microphthalmia-associated transcription factor) and its related family members TFE3, TFEB and TFEC []. They are basic helix-loop-helix leucine zipper transcription factors found in chordata. These transcription factors heterodimerize with each other and bind to the E-box core sequence (3'-CANNTG-5') [, ]. |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This entry represents a domain found at the C terminus of the MiT/TFE family members, which include MITF (microphthalmia-associated transcription factor) and its related family members TFE3, TFEB and TFEC []. They are basic helix-loop-helix leucine zipper transcription factors found in chordata. These transcription factors heterodimerize with each other and bind to the E-box core sequence (3'-CANNTG-5') [, ]. |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
136
|
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Nezich CL |
Year: |
2015 |
Journal: |
J Cell Biol |
Title: |
MiT/TFE transcription factors are activated during mitophagy downstream of Parkin and Atg5. |
Volume: |
210 |
Issue: |
3 |
Pages: |
435-50 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
The MiT/TFE family of basic helix-loop-helix leucine zipper transcription factors includes MITF (microphthalmia-associated transcription factor) and related family members TFE3, TFEB and TFEC []. The transcription factors heterodimerize with each other and recognise the same DNA sequences []. They recognise and bind E-box sequences (3'-CANNTG-5').This entry represents the transcription factor E3 (TFE3). In association with TFEB, TFE3 activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4+ T-cells and thymus-dependent humoral immunity. It also has also a role in osteoclast development []. TFE3 specifically recognises the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer []. For efficient DNA-binding, TFE3 requires dimerisation with itself or with another MiT/TFE family member, such as TFEB or MITF. |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
145
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
136
|
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Mansky KC |
Year: |
2002 |
Journal: |
J Leukoc Biol |
Title: |
The microphthalmia transcription factor and the related helix-loop-helix zipper factors TFE-3 and TFE-C collaborate to activate the tartrate-resistant acid phosphatase promoter. |
Volume: |
71 |
Issue: |
2 |
Pages: |
304-10 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
128
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
127
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
The MiT/TFE family of basic helix-loop-helix leucine zipper transcription factors includes MITF (microphthalmia-associated transcription factor) and related family members TFE3, TFEB and TFEC []. The transcription factors heterodimerize with each other and recognise the same DNA sequences []. They recognise and bind E-box sequences (3'-CANNTG-5').This entry represents transcription factor EC (TFEC). TFEC can act as a repressor or an activator. It acts as a transcriptional repressor on minimal promoter containing muE3 enhancer sequence []and as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter []. It binds DNA in a homo or heterodimeric form with MITF and TFE3. |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
93
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
105
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Kobayashi T |
Year: |
2017 |
Journal: |
Int Immunol |
Title: |
Lysosome biogenesis regulated by the amino-acid transporter SLC15A4 is critical for functional integrity of mast cells. |
Volume: |
29 |
Issue: |
12 |
Pages: |
551-566 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sergin I |
Year: |
2017 |
Journal: |
Nat Commun |
Title: |
Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis. |
Volume: |
8 |
|
Pages: |
15750 |
|
•
•
•
•
•
|
Publication |
First Author: |
Asrani K |
Year: |
2022 |
Journal: |
Nat Commun |
Title: |
An mTORC1-mediated negative feedback loop constrains amino acid-induced FLCN-Rag activation in renal cells with TSC2 loss. |
Volume: |
13 |
Issue: |
1 |
Pages: |
6808 |
|
•
•
•
•
•
|
Publication |
First Author: |
Martínez-Fábregas J |
Year: |
2018 |
Journal: |
Nat Commun |
Title: |
Lysosomal protease deficiency or substrate overload induces an oxidative-stress mediated STAT3-dependent pathway of lysosomal homeostasis. |
Volume: |
9 |
Issue: |
1 |
Pages: |
5343 |
|
•
•
•
•
•
|
Publication |
First Author: |
Calcagnì A |
Year: |
2016 |
Journal: |
Elife |
Title: |
Modelling TFE renal cell carcinoma in mice reveals a critical role of WNT signaling. |
Volume: |
5 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Dutta D |
Year: |
2022 |
Journal: |
Cell Rep |
Title: |
Treadmill exercise reduces α-synuclein spreading via PPARα. |
Volume: |
40 |
Issue: |
2 |
Pages: |
111058 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li Y |
Year: |
2016 |
Journal: |
Nat Cell Biol |
Title: |
Protein kinase C controls lysosome biogenesis independently of mTORC1. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1065-77 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang S |
Year: |
2022 |
Journal: |
Oxid Med Cell Longev |
Title: |
Activation of Transcription Factor EB Alleviates Tubular Epithelial Cell Injury via Restoring Lysosomal Homeostasis in Diabetic Nephropathy. |
Volume: |
2022 |
|
Pages: |
2812493 |
|
•
•
•
•
•
|
Publication |
First Author: |
Goodwin JM |
Year: |
2021 |
Journal: |
Sci Adv |
Title: |
GABARAP sequesters the FLCN-FNIP tumor suppressor complex to couple autophagy with lysosomal biogenesis. |
Volume: |
7 |
Issue: |
40 |
Pages: |
eabj2485 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hasan M |
Year: |
2013 |
Journal: |
Nat Immunol |
Title: |
Trex1 regulates lysosomal biogenesis and interferon-independent activation of antiviral genes. |
Volume: |
14 |
Issue: |
1 |
Pages: |
61-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chauhan S |
Year: |
2013 |
Journal: |
Mol Cell |
Title: |
ZKSCAN3 is a master transcriptional repressor of autophagy. |
Volume: |
50 |
Issue: |
1 |
Pages: |
16-28 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang X |
Year: |
2016 |
Journal: |
Nat Commun |
Title: |
MCOLN1 is a ROS sensor in lysosomes that regulates autophagy. |
Volume: |
7 |
|
Pages: |
12109 |
|
•
•
•
•
•
|
Publication |
First Author: |
Petri R |
Year: |
2017 |
Journal: |
EMBO J |
Title: |
let-7 regulates radial migration of new-born neurons through positive regulation of autophagy. |
Volume: |
36 |
Issue: |
10 |
Pages: |
1379-1391 |
|
•
•
•
•
•
|
Publication |
First Author: |
Choy CH |
Year: |
2018 |
Journal: |
J Cell Sci |
Title: |
Lysosome enlargement during inhibition of the lipid kinase PIKfyve proceeds through lysosome coalescence. |
Volume: |
131 |
Issue: |
10 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
López-Hernández T |
Year: |
2020 |
Journal: |
Nat Cell Biol |
Title: |
Endocytic regulation of cellular ion homeostasis controls lysosome biogenesis. |
Volume: |
22 |
Issue: |
7 |
Pages: |
815-827 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhu P |
Year: |
2022 |
Journal: |
Front Cardiovasc Med |
Title: |
Receptor-Interacting Protein Kinase 3 Suppresses Mitophagy Activation via the Yes-Associated Protein/Transcription Factor EB Pathways in Septic Cardiomyopathy. |
Volume: |
9 |
|
Pages: |
856041 |
|
•
•
•
•
•
|
Publication |
First Author: |
Malik N |
Year: |
2023 |
Journal: |
Science |
Title: |
Induction of lysosomal and mitochondrial biogenesis by AMPK phosphorylation of FNIP1. |
Volume: |
380 |
Issue: |
6642 |
Pages: |
eabj5559 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
572
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
572
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
539
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
537
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang J |
Year: |
2017 |
Journal: |
J Biol Chem |
Title: |
Cystinosin, the small GTPase Rab11, and the Rab7 effector RILP regulate intracellular trafficking of the chaperone-mediated autophagy receptor LAMP2A. |
Volume: |
292 |
Issue: |
25 |
Pages: |
10328-10346 |
|
•
•
•
•
•
|
Publication |
First Author: |
Min SH |
Year: |
2019 |
Journal: |
Mol Cell Biol |
Title: |
PIKfyve Deficiency in Myeloid Cells Impairs Lysosomal Homeostasis in Macrophages and Promotes Systemic Inflammation in Mice. |
Volume: |
39 |
Issue: |
21 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hashimoto Y |
Year: |
2018 |
Journal: |
Genes Cells |
Title: |
TMEM55B contributes to lysosomal homeostasis and amino acid-induced mTORC1 activation. |
Volume: |
23 |
Issue: |
6 |
Pages: |
418-434 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gatto F |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
AAV-mediated transcription factor EB (TFEB) gene delivery ameliorates muscle pathology and function in the murine model of Pompe Disease. |
Volume: |
7 |
Issue: |
1 |
Pages: |
15089 |
|
•
•
•
•
•
|
Publication |
First Author: |
Baron O |
Year: |
2017 |
Journal: |
Curr Biol |
Title: |
Stall in Canonical Autophagy-Lysosome Pathways Prompts Nucleophagy-Based Nuclear Breakdown in Neurodegeneration. |
Volume: |
27 |
Issue: |
23 |
Pages: |
3626-3642.e6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Biswas VK |
Year: |
2023 |
Journal: |
PLoS Biol |
Title: |
NCoR1 controls Mycobacterium tuberculosis growth in myeloid cells by regulating the AMPK-mTOR-TFEB axis. |
Volume: |
21 |
Issue: |
8 |
Pages: |
e3002231 |
|
•
•
•
•
•
|
Publication |
First Author: |
Song HL |
Year: |
2019 |
Journal: |
Mol Cell Neurosci |
Title: |
Ouabain activates transcription factor EB and exerts neuroprotection in models of Alzheimer's disease. |
Volume: |
95 |
|
Pages: |
13-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu M |
Year: |
2017 |
Journal: |
Am J Physiol Lung Cell Mol Physiol |
Title: |
Immunomodulators targeting MARCO expression improve resistance to postinfluenza bacterial pneumonia. |
Volume: |
313 |
Issue: |
1 |
Pages: |
L138-L153 |
|
•
•
•
•
•
|
Publication |
First Author: |
Doccini S |
Year: |
2022 |
Journal: |
Cells |
Title: |
Lysosomal Proteomics Links Disturbances in Lipid Homeostasis and Sphingolipid Metabolism to CLN5 Disease. |
Volume: |
11 |
Issue: |
11 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
McKee CA |
Year: |
2023 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Circadian clock protein BMAL1 broadly influences autophagy and endolysosomal function in astrocytes. |
Volume: |
120 |
Issue: |
20 |
Pages: |
e2220551120 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim S |
Year: |
2023 |
Journal: |
Sci Rep |
Title: |
Disruptive lysosomal-metabolic signaling and neurodevelopmental deficits that precede Purkinje cell loss in a mouse model of Niemann-Pick Type-C disease. |
Volume: |
13 |
Issue: |
1 |
Pages: |
5665 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lin W |
Year: |
2023 |
Journal: |
J Neuroinflammation |
Title: |
TNEA therapy promotes the autophagic degradation of NLRP3 inflammasome in a transgenic mouse model of Alzheimer's disease via TFEB/TFE3 activation. |
Volume: |
20 |
Issue: |
1 |
Pages: |
21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chandra S |
Year: |
2019 |
Journal: |
Neurobiol Dis |
Title: |
Cinnamic acid activates PPARα to stimulate Lysosomal biogenesis and lower Amyloid plaque pathology in an Alzheimer's disease mouse model. |
Volume: |
124 |
|
Pages: |
379-395 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chandra S |
Year: |
2018 |
Journal: |
J Neurosci |
Title: |
Aspirin Induces Lysosomal Biogenesis and Attenuates Amyloid Plaque Pathology in a Mouse Model of Alzheimer's Disease via PPARα. |
Volume: |
38 |
Issue: |
30 |
Pages: |
6682-6699 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li L |
Year: |
2024 |
Journal: |
Nat Struct Mol Biol |
Title: |
Lineage regulators TFAP2C and NR5A2 function as bipotency activators in totipotent embryos. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Kim SH |
Year: |
2017 |
Journal: |
Autophagy |
Title: |
Ezetimibe ameliorates steatohepatitis via AMP activated protein kinase-TFEB-mediated activation of autophagy and NLRP3 inflammasome inhibition. |
Volume: |
13 |
Issue: |
10 |
Pages: |
1767-1781 |
|
•
•
•
•
•
|
Publication |
First Author: |
MacLeod CM |
Year: |
2023 |
Journal: |
PLoS One |
Title: |
Trehalose enhances mitochondria deficits in human NPC1 mutant fibroblasts but disrupts mouse Purkinje cell dendritic growth ex vivo. |
Volume: |
18 |
Issue: |
11 |
Pages: |
e0294312 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chua JP |
Year: |
2014 |
Journal: |
Hum Mol Genet |
Title: |
Transcriptional activation of TFEB/ZKSCAN3 target genes underlies enhanced autophagy in spinobulbar muscular atrophy. |
Volume: |
23 |
Issue: |
5 |
Pages: |
1376-86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sun J |
Year: |
2022 |
Journal: |
Aging Cell |
Title: |
Growth differentiation factor 11 accelerates liver senescence through the inhibition of autophagy. |
Volume: |
21 |
Issue: |
1 |
Pages: |
e13532 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lotfi P |
Year: |
2018 |
Journal: |
Autophagy |
Title: |
Trehalose reduces retinal degeneration, neuroinflammation and storage burden caused by a lysosomal hydrolase deficiency. |
Volume: |
14 |
Issue: |
8 |
Pages: |
1419-1434 |
|
•
•
•
•
•
|
Publication |
First Author: |
Paquette M |
Year: |
2021 |
Journal: |
Sci Rep |
Title: |
Loss of hepatic Flcn protects against fibrosis and inflammation by activating autophagy pathways. |
Volume: |
11 |
Issue: |
1 |
Pages: |
21268 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shyam R |
Year: |
2021 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Mitochondrial ROS Induced Lysosomal Dysfunction and Autophagy Impairment in an Animal Model of Congenital Hereditary Endothelial Dystrophy. |
Volume: |
62 |
Issue: |
12 |
Pages: |
15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ma X |
Year: |
2015 |
Journal: |
Mol Cell Biol |
Title: |
Regulation of the transcription factor EB-PGC1α axis by beclin-1 controls mitochondrial quality and cardiomyocyte death under stress. |
Volume: |
35 |
Issue: |
6 |
Pages: |
956-76 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen Z |
Year: |
2018 |
Journal: |
Theranostics |
Title: |
Cardiomyocyte-Restricted Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) Deletion Leads to Lethal Dilated Cardiomyopathy Partly Through Drp1 Signaling. |
Volume: |
8 |
Issue: |
3 |
Pages: |
627-643 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stagi M |
Year: |
2014 |
Journal: |
Mol Cell Neurosci |
Title: |
Lysosome size, motility and stress response regulated by fronto-temporal dementia modifier TMEM106B. |
Volume: |
61 |
|
Pages: |
226-40 |
|
•
•
•
•
•
|
Publication |
First Author: |
Theeuwes WF |
Year: |
2020 |
Journal: |
Biochim Biophys Acta Mol Cell Res |
Title: |
Regulation of PGC-1α expression by a GSK-3β-TFEB signaling axis in skeletal muscle. |
Volume: |
1867 |
Issue: |
2 |
Pages: |
118610 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lim SW |
Year: |
2019 |
Journal: |
FASEB J |
Title: |
Effect of Klotho on autophagy clearance in tacrolimus-induced renal injury. |
Volume: |
33 |
Issue: |
2 |
Pages: |
2694-2706 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim S |
Year: |
2020 |
Journal: |
Autophagy |
Title: |
ESRRA (estrogen related receptor alpha) is a critical regulator of intestinal homeostasis through activation of autophagic flux via gut microbiota. |
|
|
Pages: |
1-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cinque L |
Year: |
2020 |
Journal: |
EMBO J |
Title: |
MiT/TFE factors control ER-phagy via transcriptional regulation of FAM134B. |
Volume: |
39 |
Issue: |
17 |
Pages: |
e105696 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yan Q |
Year: |
2017 |
Journal: |
Mol Pharmacol |
Title: |
Activation of AMPK/mTORC1-Mediated Autophagy by Metformin Reverses Clk1 Deficiency-Sensitized Dopaminergic Neuronal Death. |
Volume: |
92 |
Issue: |
6 |
Pages: |
640-652 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ni H |
Year: |
2020 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Nicotine Modulates CTSS (Cathepsin S) Synthesis and Secretion Through Regulating the Autophagy-Lysosomal Machinery in Atherosclerosis. |
Volume: |
40 |
Issue: |
9 |
Pages: |
2054-2069 |
|
•
•
•
•
•
|
Publication |
First Author: |
Akwa Y |
Year: |
2023 |
Journal: |
Autophagy |
Title: |
Stimulation of synaptic activity promotes TFEB-mediated clearance of pathological MAPT/Tau in cellular and mouse models of tauopathies. |
Volume: |
19 |
Issue: |
2 |
Pages: |
660-677 |
|
•
•
•
•
•
|
Publication |
First Author: |
Reed CB |
Year: |
2020 |
Journal: |
J Neurosci |
Title: |
Deletion of Calcineurin in Schwann Cells Does Not Affect Developmental Myelination, But Reduces Autophagy and Delays Myelin Clearance after Peripheral Nerve Injury. |
Volume: |
40 |
Issue: |
32 |
Pages: |
6165-6176 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nakashima A |
Year: |
2020 |
Journal: |
Autophagy |
Title: |
Evidence for lysosomal biogenesis proteome defect and impaired autophagy in preeclampsia. |
Volume: |
16 |
Issue: |
10 |
Pages: |
1771-1785 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tanaka Y |
Year: |
2013 |
Journal: |
Neuroscience |
Title: |
Increased lysosomal biogenesis in activated microglia and exacerbated neuronal damage after traumatic brain injury in progranulin-deficient mice. |
Volume: |
250 |
|
Pages: |
8-19 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim HK |
Year: |
2021 |
Journal: |
Autophagy |
Title: |
TMBIM6 (transmembrane BAX inhibitor motif containing 6) enhances autophagy through regulation of lysosomal calcium. |
Volume: |
17 |
Issue: |
3 |
Pages: |
761-778 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhao X |
Year: |
2018 |
Journal: |
J Pathol |
Title: |
Advanced glycation end-products suppress autophagic flux in podocytes by activating mammalian target of rapamycin and inhibiting nuclear translocation of transcription factor EB. |
Volume: |
245 |
Issue: |
2 |
Pages: |
235-248 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gu S |
Year: |
2020 |
Journal: |
Circ Res |
Title: |
Downregulation of LAPTM4B Contributes to the Impairment of the Autophagic Flux via Unopposed Activation of mTORC1 Signaling During Myocardial Ischemia/Reperfusion Injury. |
Volume: |
127 |
Issue: |
7 |
Pages: |
e148-e165 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang YT |
Year: |
2019 |
Journal: |
Am J Physiol Cell Physiol |
Title: |
Contribution of transcription factor EB to adipoRon-induced inhibition of arterial smooth muscle cell proliferation and migration. |
Volume: |
317 |
Issue: |
5 |
Pages: |
C1034-C1047 |
|
•
•
•
•
•
|
Publication |
First Author: |
Albanese F |
Year: |
2021 |
Journal: |
Neurobiol Dis |
Title: |
Constitutive silencing of LRRK2 kinase activity leads to early glucocerebrosidase deregulation and late impairment of autophagy in vivo. |
Volume: |
159 |
|
Pages: |
105487 |
|
•
•
•
•
•
|
Publication |
First Author: |
Klein M |
Year: |
2022 |
Journal: |
Autophagy |
Title: |
Converging roles of PSENEN/PEN2 and CLN3 in the autophagy-lysosome system. |
Volume: |
18 |
Issue: |
9 |
Pages: |
2068-2085 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang SM |
Year: |
2023 |
Journal: |
Autophagy |
Title: |
Nucleoporin POM121 signals TFEB-mediated autophagy via activation of SIGMAR1/sigma-1 receptor chaperone by pridopidine. |
Volume: |
19 |
Issue: |
1 |
Pages: |
126-151 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pan B |
Year: |
2019 |
Journal: |
Front Physiol |
Title: |
Highly Dynamic Changes in the Activity and Regulation of Macroautophagy in Hearts Subjected to Increased Proteotoxic Stress. |
Volume: |
10 |
|
Pages: |
758 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang L |
Year: |
2022 |
Journal: |
Autophagy |
Title: |
Torin 1 alleviates impairment of TFEB-mediated lysosomal biogenesis and autophagy in TGFBI (p.G623_H626del)-linked Thiel-Behnke corneal dystrophy. |
Volume: |
18 |
Issue: |
4 |
Pages: |
765-782 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
526
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
317
|
Fragment?: |
false |
|
•
•
•
•
•
|