|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 601 to 684 out of 684 for Gapdh

<< First    < Previous  |  Next >    Last >>
0.028s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Protein
Organism: Mus musculus/domesticus
Length: 333  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 359  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 440  
Fragment?: false
Protein Domain
Type: Family
Description: This entry includes CP12, a chloroplast protein that regulates the Calvin cycle responsible for CO2 assimilation []. Oxidized CP12 forms a supramolecular complex with two key Calvin cycle enzymes, GAPDH (glyceraldehyde-3-phosphate dehydrogenase) and PRK (phosphoribulokinase), down-regulating their activity. It also interacts with other enzymes such as aldolase and malate dehydrogenase []. This entry also includes proteins from Cyanobacteria (blue-green algae).
Pseudogene
Type: pseudogene
Organism: mouse, laboratory
Pseudogene
Type: pseudogene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 118  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 57  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 55  
Fragment?: true
Publication
First Author: Graciet E
Year: 2003
Journal: Biochemistry
Title: The small protein CP12: a protein linker for supramolecular complex assembly.
Volume: 42
Issue: 27
Pages: 8163-70
Publication
First Author: Gontero B
Year: 2012
Journal: Biochem Soc Trans
Title: An intrinsically disordered protein, CP12: jack of all trades and master of the Calvin cycle.
Volume: 40
Issue: 5
Pages: 995-9
Protein Domain
Type: Family
Description: This entry contains a small clade of dehydrogenases in gamma-proteobacteria which utilise NAD+ to oxidize erythrose-4-phosphate (E4P) to 4-phospho-erythronate, a precursor for the de novo synthesis of pyridoxine via 4-hydroxythreonine and D-1-deoxyxylulose []. This enzyme activity appears to have evolved from glyceraldehyde-3-phosphate dehydrogenase, whose substrate differs only in the lack of one carbon relative to E4P. It is possible that some of the GAPDH enzymes may prove to be bifunctional in certain species.
Protein Domain
Type: Domain
Description: This entry represents an uncharacterised domain found in calvin cycle protein CP12 and other proteins. This domain is sometimes found in association cystathionine-beta-synthase domains.CP12 is a chloroplast protein that regulates the Calvin cycle responsible for CO2 assimilation []. Oxidized CP12 forms a supramolecular complex with two key Calvin cycle enzymes, GAPDH (glyceraldehyde-3-phosphate dehydrogenase) and PRK (phosphoribulokinase), down-regulating their activity. It also interacts with other enzymes such as aldolase and malate dehydrogenase [].
Publication
First Author: Fillinger S
Year: 2000
Journal: J Biol Chem
Title: Two glyceraldehyde-3-phosphate dehydrogenases with opposite physiological roles in a nonphotosynthetic bacterium.
Volume: 275
Issue: 19
Pages: 14031-7
Publication
First Author: Mittenhuber G
Year: 2001
Journal: J Mol Microbiol Biotechnol
Title: Phylogenetic analyses and comparative genomics of vitamin B6 (pyridoxine) and pyridoxal phosphate biosynthesis pathways.
Volume: 3
Issue: 1
Pages: 1-20
Publication
First Author: Boschi-Muller S
Year: 1997
Journal: J Biol Chem
Title: Comparative enzymatic properties of GapB-encoded erythrose-4-phosphate dehydrogenase of Escherichia coli and phosphorylating glyceraldehyde-3-phosphate dehydrogenase.
Volume: 272
Issue: 24
Pages: 15106-12
Protein Domain
Type: Family
Description: This group of sequences represent glyceraldehyde-3-phosphate dehydrogenase (GAPDH), the enzyme responsible for the interconversion of 1,3-diphosphoglycerate and glyceraldehyde-3-phosphate, a central step in glycolysis and gluconeogenesis. Forms exist which utilise NAD (), NADP () or either (). In some species, NAD- and NADP- utilising forms exist, generally being responsible for reactions in the anabolic and catabolic directions respectively []. An additional form of gap gene is found in gamma proteobacteria and is responsible for the conversion of erythrose-4-phosphate (E4P) to 4-phospho-erythronate in the biosynthesis of pyridoxine []. This pathway of pyridoxine biosynthesis appears to be limited, however, to a relatively small number of bacterial species although it is prevalent among the gamma-proteobacteria []. This enzyme is described by . These two groups of sequences exhibit a close evolutionary relationship. There exists the possibility that some forms of GAPDH may be bifunctional and act on E4P in species which make pyridoxine and via hydroxythreonine and lack a separate E4PDH enzyme (for instance, the GAPDH from Bacillus stearothermophilus has been shown to possess a limited E4PD activity as well as a robust GAPDH activity []).
Publication
First Author: Xu R
Year: 2013
Journal: Neuron
Title: Behavioral effects of cocaine mediated by nitric oxide-GAPDH transcriptional signaling.
Volume: 78
Issue: 4
Pages: 623-30
Publication
First Author: Kaluzhny Y
Year: 2002
Journal: FEBS Lett
Title: A selective effect of Mpl ligand on mRNA stabilization during megakaryocyte differentiation.
Volume: 527
Issue: 1-3
Pages: 279-83
Publication
First Author: Snider NT
Year: 2016
Journal: PLoS One
Title: Ethanol and Acetaminophen Synergistically Induce Hepatic Aggregation and TCH346-Insensitive Nuclear Translocation of GAPDH.
Volume: 11
Issue: 8
Pages: e0160982
HT Experiment
Series Id: GSE7217
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: ArrayExpress
Publication
First Author: Zhu Y
Year: 2019
Journal: J Exp Med
Title: The E3 ligase VHL promotes follicular helper T cell differentiation via glycolytic-epigenetic control.
Volume: 216
Issue: 7
Pages: 1664-1681
Publication
First Author: Shin MK
Year: 2021
Journal: Cell
Title: Reducing acetylated tau is neuroprotective in brain injury.
Volume: 184
Issue: 10
Pages: 2715-2732.e23
Publication
First Author: Zala D
Year: 2013
Journal: Cell
Title: Vesicular glycolysis provides on-board energy for fast axonal transport.
Volume: 152
Issue: 3
Pages: 479-91
Publication
First Author: Yun J
Year: 2015
Journal: Science
Title: Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH.
Volume: 350
Issue: 6266
Pages: 1391-6
Publication
First Author: Wiel C
Year: 2019
Journal: Cell
Title: BACH1 Stabilization by Antioxidants Stimulates Lung Cancer Metastasis.
Volume: 178
Issue: 2
Pages: 330-345.e22
Publication
First Author: Sun B
Year: 2009
Journal: Mol Genet Metab
Title: Activation of glycolysis and apoptosis in glycogen storage disease type Ia.
Volume: 97
Issue: 4
Pages: 267-71
Publication
First Author: Haythorne E
Year: 2022
Journal: Nat Commun
Title: Altered glycolysis triggers impaired mitochondrial metabolism and mTORC1 activation in diabetic β-cells.
Volume: 13
Issue: 1
Pages: 6754
Publication
First Author: De Jesus A
Year: 2022
Journal: Mol Cell
Title: Hexokinase 1 cellular localization regulates the metabolic fate of glucose.
Volume: 82
Issue: 7
Pages: 1261-1277.e9
Publication
First Author: Lau EC
Year: 1993
Journal: J Steroid Biochem Mol Biol
Title: Messenger RNA phenotyping for semi-quantitative comparison of glucocorticoid receptor transcript levels in the developing embryonic mouse palate.
Volume: 46
Issue: 6
Pages: 751-8
Publication
First Author: Hidai C
Year: 2003
Journal: Biochem Biophys Res Commun
Title: Specific regulation of nucleocytoplasmic distribution of poly(C)-binding protein gene mRNA in mouse development.
Volume: 309
Issue: 2
Pages: 339-43
Publication  
First Author: Hinckelmann MV
Year: 2016
Journal: Nat Commun
Title: Self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport.
Volume: 7
Pages: 13233
Publication
First Author: Balmer ML
Year: 2016
Journal: Immunity
Title: Memory CD8(+) T Cells Require Increased Concentrations of Acetate Induced by Stress for Optimal Function.
Volume: 44
Issue: 6
Pages: 1312-24
Publication
First Author: Rodrigues DC
Year: 2020
Journal: Nat Commun
Title: Methylglyoxal couples metabolic and translational control of Notch signalling in mammalian neural stem cells.
Volume: 11
Issue: 1
Pages: 2018
Publication    
First Author: Gnanapradeepan K
Year: 2020
Journal: Elife
Title: Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser.
Volume: 9
Publication
First Author: Sisu C
Year: 2020
Journal: Nat Commun
Title: Transcriptional activity and strain-specific history of mouse pseudogenes.
Volume: 11
Issue: 1
Pages: 3695
HT Experiment
Series Id: GSE8027
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Miki K
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Glyceraldehyde 3-phosphate dehydrogenase-S, a sperm-specific glycolytic enzyme, is required for sperm motility and male fertility.
Volume: 101
Issue: 47
Pages: 16501-6
Publication
First Author: Yamaji R
Year: 2003
Journal: Biochim Biophys Acta
Title: Hypoxia up-regulates glyceraldehyde-3-phosphate dehydrogenase in mouse brain capillary endothelial cells: involvement of Na+/Ca2+ exchanger.
Volume: 1593
Issue: 2-3
Pages: 269-76
Publication
First Author: Wisser KC
Year: 2004
Journal: Arch Biochem Biophys
Title: Mapping tissue-specific genes correlated with age-dependent changes in protein stability and function.
Volume: 432
Issue: 1
Pages: 58-70
Publication
First Author: Giulivi C
Year: 2011
Journal: J Biol Chem
Title: Basal bioenergetic abnormalities in skeletal muscle from ryanodine receptor malignant hyperthermia-susceptible R163C knock-in mice.
Volume: 286
Issue: 1
Pages: 99-113
Publication
First Author: Yagi M
Year: 2021
Journal: EMBO J
Title: Mitochondrial translation deficiency impairs NAD+ -mediated lysosomal acidification.
Volume: 40
Issue: 8
Pages: e105268
Publication
First Author: Cho W
Year: 2009
Journal: J Neurochem
Title: Dual transgenic reporter mice as a tool for monitoring expression of glial fibrillary acidic protein.
Volume: 110
Issue: 1
Pages: 343-51
Publication
First Author: Temme A
Year: 2000
Journal: Cell Tissue Res
Title: Acute-phase response and circadian expression of connexin26 are not altered in connexin32-deficient mouse liver.
Volume: 300
Issue: 1
Pages: 111-7
Publication  
First Author: Stork BA
Year: 2022
Journal: Mol Metab
Title: Calcium/calmodulin-dependent protein kinase kinase 2 regulates hepatic fuel metabolism.
Volume: 62
Pages: 101513
Publication
First Author: Wang B
Year: 2017
Journal: Aging Cell
Title: The oxidized thiol proteome in aging and cataractous mouse and human lens revealed by ICAT labeling.
Volume: 16
Issue: 2
Pages: 244-261
Publication
First Author: Johnson AW
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Cognitive and motivational deficits together with prefrontal oxidative stress in a mouse model for neuropsychiatric illness.
Volume: 110
Issue: 30
Pages: 12462-7
Publication
First Author: Cai R
Year: 2015
Journal: FASEB J
Title: Overexpression of glyceraldehyde 3-phosphate dehydrogenase prevents neurovascular degeneration after retinal injury.
Volume: 29
Issue: 7
Pages: 2749-58
Publication
First Author: Brorson K
Year: 1997
Journal: J Immunol
Title: xid affects events leading to B cell cycle entry.
Volume: 159
Issue: 1
Pages: 135-43
Publication
First Author: Roy C
Year: 2008
Journal: Am J Physiol Endocrinol Metab
Title: Shift in metabolic fuel in acylation-stimulating protein-deficient mice following a high-fat diet.
Volume: 294
Issue: 6
Pages: E1051-9
Publication
First Author: Napolitano G
Year: 2015
Journal: EMBO Mol Med
Title: Impairment of chaperone-mediated autophagy leads to selective lysosomal degradation defects in the lysosomal storage disease cystinosis.
Volume: 7
Issue: 2
Pages: 158-74
Publication
First Author: McBride MJ
Year: 2017
Journal: Am J Physiol Endocrinol Metab
Title: The NLRP3 inflammasome contributes to sarcopenia and lower muscle glycolytic potential in old mice.
Volume: 313
Issue: 2
Pages: E222-E232
Publication  
First Author: Desseille C
Year: 2017
Journal: Front Mol Neurosci
Title: Specific Physical Exercise Improves Energetic Metabolism in the Skeletal Muscle of Amyotrophic-Lateral- Sclerosis Mice.
Volume: 10
Pages: 332
Publication
First Author: Esteves TC
Year: 2012
Journal: PLoS One
Title: Mitochondrial physiology and gene expression analyses reveal metabolic and translational dysregulation in oocyte-induced somatic nuclear reprogramming.
Volume: 7
Issue: 6
Pages: e36850
Publication
First Author: Nakano S
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Role of extracellular vesicles in the interaction between epithelial and mesenchymal cells during oviductal ciliogenesis.
Volume: 483
Issue: 1
Pages: 245-251
Publication
First Author: Carkaci-Salli N
Year: 2012
Journal: J Neurosci Res
Title: Gender-specific regulation of tyrosine hydroxylase in thymocyte differentiation antigen-1 knockout mice.
Volume: 90
Issue: 8
Pages: 1583-8
Publication
First Author: Ding J
Year: 2011
Journal: Mol Reprod Dev
Title: Aurora kinase-A regulates microtubule organizing center (MTOC) localization, chromosome dynamics, and histone-H3 phosphorylation in mouse oocytes.
Volume: 78
Issue: 2
Pages: 80-90
Publication
First Author: Zhu G
Year: 2001
Journal: Biochem Biophys Res Commun
Title: Fudenine, a C-terminal truncated rat homologue of mouse prominin, is blood glucose-regulated and can up-regulate the expression of GAPDH.
Volume: 281
Issue: 4
Pages: 951-6
Publication
First Author: Olichon-Berthe C
Year: 1992
Journal: Mol Cell Endocrinol
Title: Effect of cold acclimation on the expression of glucose transporter Glut 4.
Volume: 89
Issue: 1-2
Pages: 11-8
Publication
First Author: Ferber S
Year: 1994
Journal: Metabolism
Title: Vanadate normalizes hyperglycemia and phosphoenolpyruvate carboxykinase mRNA levels in ob/ob mice.
Volume: 43
Issue: 11
Pages: 1346-54
Publication
First Author: Gallogly MM
Year: 2008
Journal: Biochemistry
Title: Kinetic and mechanistic characterization and versatile catalytic properties of mammalian glutaredoxin 2: implications for intracellular roles.
Volume: 47
Issue: 42
Pages: 11144-57
Publication
First Author: Hanke N
Year: 2011
Journal: Biochim Biophys Acta
Title: Gene regulation mediating fiber-type transformation in skeletal muscle cells is partly glucose- and ChREBP-dependent.
Volume: 1813
Issue: 3
Pages: 377-89
Publication
First Author: Buller CL
Year: 2011
Journal: Am J Physiol Renal Physiol
Title: GLUT1 enhances mTOR activity independently of TSC2 and AMPK.
Volume: 301
Issue: 3
Pages: F588-96
Publication
First Author: Adastra KL
Year: 2011
Journal: Reproduction
Title: A differential autophagic response to hyperglycemia in the developing murine embryo.
Volume: 141
Issue: 5
Pages: 607-15
Publication
First Author: Loers G
Year: 2012
Journal: J Neurosci
Title: The interaction between cell adhesion molecule L1, matrix metalloproteinase 14, and adenine nucleotide translocator at the plasma membrane regulates L1-mediated neurite outgrowth of murine cerebellar neurons.
Volume: 32
Issue: 11
Pages: 3917-30
Publication
First Author: Meng Z
Year: 2013
Journal: PLoS One
Title: RNAi induces innate immunity through multiple cellular signaling pathways.
Volume: 8
Issue: 5
Pages: e64708
Publication
First Author: Kolodney G
Year: 2015
Journal: J Biol Chem
Title: Nuclear Compartmentalization of Serine Racemase Regulates D-Serine Production: IMPLICATIONS FOR N-METHYL-D-ASPARTATE (NMDA) RECEPTOR ACTIVATION.
Volume: 290
Issue: 52
Pages: 31037-50
Publication
First Author: Guha P
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Cocaine elicits autophagic cytotoxicity via a nitric oxide-GAPDH signaling cascade.
Volume: 113
Issue: 5
Pages: 1417-22
Publication
First Author: Hosokawa K
Year: 2017
Journal: Am J Physiol Endocrinol Metab
Title: S100B impairs glycolysis via enhanced poly(ADP-ribosyl)ation of glyceraldehyde-3-phosphate dehydrogenase in rodent muscle cells.
Volume: 312
Issue: 6
Pages: E471-E481
Publication  
First Author: Chakravarti R
Year: 2015
Journal: Free Radic Biol Med
Title: Novel insights in mammalian catalase heme maturation: effect of NO and thioredoxin-1.
Volume: 82
Pages: 105-13
Publication  
First Author: Pretsch W
Year: 1988
Journal: Mouse News Lett
Title: Linkage of Tpi-1 and Gapd
Volume: 80
Pages: 175
Publication
First Author: Zelenchuk LV
Year: 2014
Journal: PLoS One
Title: PHEX mimetic (SPR4-peptide) corrects and improves HYP and wild type mice energy-metabolism.
Volume: 9
Issue: 5
Pages: e97326
Publication
First Author: Pelzl L
Year: 2013
Journal: Cell Physiol Biochem
Title: Sgk1 sensitive pendrin expression in murine platelets.
Volume: 32
Issue: 7
Pages: 210-20
Publication
First Author: Yao J
Year: 1997
Journal: Brain Res Mol Brain Res
Title: Induction of interleukin-1 beta-converting enzyme (ICE) in murine microglia by lipopolysaccharide.
Volume: 51
Issue: 1-2
Pages: 170-8
Publication
First Author: Little R
Year: 2011
Journal: PLoS One
Title: The transient receptor potential ion channel TRPV6 is expressed at low levels in osteoblasts and has little role in osteoblast calcium uptake.
Volume: 6
Issue: 11
Pages: e28166
Publication  
First Author: Albanese F
Year: 2021
Journal: Neurobiol Dis
Title: Constitutive silencing of LRRK2 kinase activity leads to early glucocerebrosidase deregulation and late impairment of autophagy in vivo.
Volume: 159
Pages: 105487
Publication
First Author: Ho PW
Year: 2020
Journal: Autophagy
Title: Age-dependent accumulation of oligomeric SNCA/α-synuclein from impaired degradation in mutant LRRK2 knockin mouse model of Parkinson disease: role for therapeutic activation of chaperone-mediated autophagy (CMA).
Volume: 16
Issue: 2
Pages: 347-370
Publication
First Author: Zoumpoulidou G
Year: 2012
Journal: J Natl Cancer Inst
Title: Role of the tripartite motif protein 27 in cancer development.
Volume: 104
Issue: 12
Pages: 941-52
Publication
First Author: Niu C
Year: 2019
Journal: Autophagy
Title: Metformin alleviates hyperglycemia-induced endothelial impairment by downregulating autophagy via the Hedgehog pathway.
Volume: 15
Issue: 5
Pages: 843-870
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7