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Search results 101 to 148 out of 148 for Cdnf

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0.022s
Type Details Score
GXD Expression  
Probe: MGI:6719224
Assay Type: RNA in situ
Annotation Date: 2021-07-07
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6719233
Age: postnatal day 10
Note: Expression most intense in hippocampus and thalamus.
Specimen Label: S3e
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:6719224
Assay Type: RNA in situ
Annotation Date: 2021-07-07
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6719233
Age: postnatal day 10
Note: Expression most intense in hippocampus and thalamus.
Specimen Label: S3n
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:6719224
Assay Type: RNA in situ
Annotation Date: 2021-07-07
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754027
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6719233
Age: postnatal day 1
Specimen Label: S3u
Detected: true
Specimen Num: 13
GXD Expression    
Probe: MGI:6719226
Assay Type: Immunohistochemistry
Annotation Date: 2021-07-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754027
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6719235
Age: postnatal day 1
Specimen Label: S5f
Detected: true
Specimen Num: 12
GXD Expression    
Probe: MGI:6719226
Assay Type: Immunohistochemistry
Annotation Date: 2021-07-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6719235
Age: postnatal day 10
Specimen Label: S5b
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:6719224
Assay Type: RNA in situ
Annotation Date: 2021-07-07
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3280927
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6719233
Age: postnatal day 1
Specimen Label: S3q
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:6719226
Assay Type: Immunohistochemistry
Annotation Date: 2021-07-07
Strength: Present
Sex: Male
Emaps: EMAPS:3527628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6719235
Age: postnatal adult
Specimen Label: not shown
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6719224
Assay Type: RNA in situ
Annotation Date: 2021-07-07
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6719233
Age: postnatal day 10
Specimen Label: S3a
Specimen Num: 1
GXD Expression      
Probe: MGI:6719224
Assay Type: RNA in situ
Annotation Date: 2021-07-07
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6719233
Age: postnatal day 10
Specimen Label: S3k
Specimen Num: 6
Publication  
First Author: Pakarinen E
Year: 2020
Journal: eNeuro
Title: MANF Ablation Causes Prolonged Activation of the UPR without Neurodegeneration in the Mouse Midbrain Dopamine System.
Volume: 7
Issue: 1
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
Publication        
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Allele
Name: cerebral dopamine neurotrophic factor; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Publication
First Author: Lindahl M
Year: 2017
Journal: Neurobiol Dis
Title: Unconventional neurotrophic factors CDNF and MANF: Structure, physiological functions and therapeutic potential.
Volume: 97
Issue: Pt B
Pages: 90-102
Publication  
First Author: Kemppainen S
Year: 2015
Journal: Behav Brain Res
Title: Cerebral dopamine neurotrophic factor improves long-term memory in APP/PS1 transgenic mice modeling Alzheimer's disease as well as in wild-type mice.
Volume: 291
Pages: 1-11
Publication
First Author: Mizobuchi N
Year: 2007
Journal: Cell Struct Funct
Title: ARMET is a soluble ER protein induced by the unfolded protein response via ERSE-II element.
Volume: 32
Issue: 1
Pages: 41-50
Publication
First Author: Zhou C
Year: 2006
Journal: Neuroreport
Title: Mesencephalic astrocyte-derived neurotrophic factor enhances nigral gamma-aminobutyric acid release.
Volume: 17
Issue: 3
Pages: 293-7
Protein Domain
Type: Domain
Description: This entry represents the C-terminal domain of ARMET.ARMET, also known as mesencephalic astrocyte-derived neurotrophic factor (MANF) or arginine-rich protein, is a small protein of approximately 170 residues which contains four di-sulphide bridges that are highly conserved from nematodes to humans. It is a soluble protein resident in the endoplasmic reticulum and induced by ER stress. It appears to be involved with dealing with mis-folded proteins in the ER, thus in quality control of ER stress []. ARMET from Rattus norvegicus (Rat) selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. It modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra, and enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons [].Proteins containing this domain includes the related neurotrophic factor CDNF (cerebral dopamine neurotrophic factor) [].
Protein Domain
Type: Domain
Description: This entry represents the N-terminal domain of ARMET.ARMET, also known as mesencephalic astrocyte-derived neurotrophic factor (MANF) or arginine-rich protein, is a small protein of approximately 170 residues which contains four di-sulphide bridges that are highly conserved from nematodes to humans. It is a soluble protein resident in the endoplasmic reticulum and induced by ER stress. It appears to be involved with dealing with mis-folded proteins in the ER, thus in quality control of ER stress []. ARMET from Rattus norvegicus (Rat) selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. It modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra, and enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons [].Proteins containing this domain includes the related neurotrophic factor CDNF (cerebral dopamine neurotrophic factor) [].
Protein Domain
Type: Family
Description: ARMET, also known as mesencephalic astrocyte-derived neurotrophic factor (MANF) or arginine-rich protein, is a small protein of approximately 170 residues which contains four di-sulphide bridges that are highly conserved from nematodes to humans. It is a soluble protein resident in the endoplasmic reticulum and induced by ER stress. It appears to be involved with dealing with mis-folded proteins in the ER, thus in quality control of ER stress []. ARMET from Rattus norvegicus (Rat) selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. It modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra, and enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons [].This entry also includes the related neurotrophic factor CDNF (cerebral dopamine neurotrophic factor) [].
Protein
Organism: Mus musculus/domesticus
Length: 52  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 128  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 121  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 179  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 187  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 170  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 179  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 165  
Fragment?: false