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Search results 1301 to 1362 out of 1362 for Satb2

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:7579005
Assay Type: RNA in situ
Annotation Date: 2024-01-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271120
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7579034
Age: embryonic day 12.5
Note: Co-expression with Satb2 in almost half of Satb2 expressing neurons.
Specimen Label: 2d E12.5 mRNA Bcl11b
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7620101
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3558827
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:7620362
Age: postnatal day 0
Image: 7M,N
Note: There was a striking loss of expression in the upper layers of the Satb2 mutants.
Specimen Label: 7M,N
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-04-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7620251
Age: postnatal
Image: 6C
Note: Satb2 mutants show a reduction in PLAP+ axons traversing the striatum.
Specimen Label: 6C
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
Probe: MGI:7620324
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-04-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7620322
Age: postnatal
Image: 6L
Note: Satb2 mutants show a reduction in PLAP+ axons traversing the striatum.
Specimen Label: 6L
Detected: true
Specimen Num: 2
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Allele
Satb2<tm1.1(cre/ERT2)Slp> | MGI:7439756
Name: special AT-rich sequence binding protein 2; targeted mutation 1.1, Samuel L Pfaff
Allele Type: Targeted
Attribute String: Inducible, Recombinase
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GXD Expression
GXD Expression
Probe: MGI:7620104
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3558828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7620298
Age: postnatal day 4
Image: 5B
Note: Satb2 conditional knockouts show reduced Tbr1 in layers 6 and 5, and a loss of Tbr1 in the upper layers.
Specimen Label: 5B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7620104
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3558828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7620298
Age: postnatal day 4
Image: 5B
Note: Satb2 conditional knockouts show reduced Tbr1 in layers 6 and 5, and a loss of Tbr1 in the upper layers.
Specimen Label: 5B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7620104
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3558828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7620298
Age: postnatal day 4
Image: 5B
Note: Satb2 conditional knockouts show reduced Tbr1 in layers 6 and 5, and a loss of Tbr1 in the upper layers.
Specimen Label: 5B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7620104
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3558828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7620298
Age: postnatal day 4
Image: 5B
Note: Satb2 conditional knockouts show reduced Tbr1 in layers 6 and 5, and a loss of Tbr1 in the upper layers.
Specimen Label: 5B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7620104
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3558828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7620298
Age: postnatal day 4
Image: 5B
Note: Satb2 conditional knockouts show reduced Tbr1 in layers 6 and 5, and a loss of Tbr1 in the upper layers.
Specimen Label: 5B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7620104
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3558828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7620298
Age: postnatal day 4
Image: 5B
Note: Satb2 conditional knockouts show reduced Tbr1 in layers 6 and 5, and a loss of Tbr1 in the upper layers.
Specimen Label: 5B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7620104
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3558828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7620298
Age: postnatal day 4
Image: 5B
Note: Satb2 conditional knockouts show reduced Tbr1 in layers 6 and 5, and a loss of Tbr1 in the upper layers.
Specimen Label: 5B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7620104
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3558828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7620298
Age: postnatal day 4
Image: 5B
Note: Satb2 conditional knockouts show reduced Tbr1 in layers 6 and 5, and a loss of Tbr1 in the upper layers.
Specimen Label: 5B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7620104
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3558828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7620298
Age: postnatal day 4
Image: 5B
Note: Satb2 conditional knockouts show reduced Tbr1 in layers 6 and 5, and a loss of Tbr1 in the upper layers.
Specimen Label: 5B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7620104
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3558828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7620298
Age: postnatal day 4
Image: 5B
Note: Satb2 conditional knockouts show reduced Tbr1 in layers 6 and 5, and a loss of Tbr1 in the upper layers.
Specimen Label: 5B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7620104
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3558828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7620298
Age: postnatal day 4
Image: 5B
Note: Satb2 conditional knockouts show reduced Tbr1 in layers 6 and 5, and a loss of Tbr1 in the upper layers.
Specimen Label: 5B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7620104
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3558828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7620298
Age: postnatal day 4
Image: 5B
Note: Satb2 conditional knockouts show reduced Tbr1 in layers 6 and 5, and a loss of Tbr1 in the upper layers.
Specimen Label: 5B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7620104
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3558828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7620298
Age: postnatal day 4
Image: 5B
Note: Satb2 conditional knockouts show reduced Tbr1 in layers 6 and 5, and a loss of Tbr1 in the upper layers.
Specimen Label: 5B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7620104
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3558828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7620298
Age: postnatal day 4
Image: 5B
Note: Satb2 conditional knockouts show reduced Tbr1 in layers 6 and 5, and a loss of Tbr1 in the upper layers.
Specimen Label: 5B
Detected: true
Specimen Num: 2
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Allele
Satb2<em1Smoc> | MGI:7292169
Name: special AT-rich sequence binding protein 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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GXD Expression
GXD Expression
Probe: MGI:5447971
Assay Type: Immunohistochemistry
Annotation Date: 2023-02-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284226
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7432928
Age: embryonic day 18.5
Image: 5C Kat7lox/lox NesCreT/+
Note: Cells expressing Ctip2 (Bcl11b) only were overrepresented in superficial layers. Abnormally high number of cells co-expressing Ctip2 and Satb2 in superficial layers.
Specimen Label: 5C Kat7lox/lox NesCreT/+
Detected: true
Specimen Num: 2
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Allele
Tg(Satb2-cre)MO23Gsat | MGI:4940657
Name: transgene insertion MO23, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Recombinase
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Allele
Tg(Satb2-cre)MO18Gsat | MGI:5051792
Name: transgene insertion MO18, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Recombinase
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DO Term
DOID:0060428 | SATB2-associated syndrome
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Strain
MGI:5004259 | STOCK Tg(Satb2-cre)MO23Gsat/Mmucd
Attribute String: mutant stock, transgenic
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Strain
MGI:5519923 | STOCK Tg(Satb2-cre)MO18Gsat/Mmucd
Attribute String: mutant stock, transgenic
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Publication
15851481 | J:100849
First Author: Seo J
Year: 2005
Journal: J Biol Chem
Title: Nuclear matrix binding regulates SATB1-mediated transcriptional repression.
Volume: 280
Issue: 26
Pages: 24600-9
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Protein
D3Z4F8
Organism: Mus musculus/domesticus
Length: 74  
Fragment?: true
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Publication
14701874 | -
First Author: Dobreva G
Year: 2003
Journal: Genes Dev
Title: SUMO modification of a novel MAR-binding protein, SATB2, modulates immunoglobulin mu gene expression.
Volume: 17
Issue: 24
Pages: 3048-61
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Publication
16630892 | -
First Author: Pavan Kumar P
Year: 2006
Journal: Mol Cell
Title: Phosphorylation of SATB1, a global gene regulator, acts as a molecular switch regulating its transcriptional activity in vivo.
Volume: 22
Issue: 2
Pages: 231-43
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Publication
28139846 | -
First Author: Zarate YA
Year: 2017
Journal: Clin Genet
Title: Genotype and phenotype in 12 additional individuals with SATB2-associated syndrome.
Volume: 92
Issue: 4
Pages: 423-429
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Publication
27774744 | -
First Author: Zarate YA
Year: 2017
Journal: Am J Med Genet A
Title: SATB2-associated syndrome: Mechanisms, phenotype, and practical recommendations.
Volume: 173
Issue: 2
Pages: 327-337
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Publication
29772444 | -
 
First Author: Sunkara KP
Year: 2018
Journal: Biomed Pharmacother
Title: Functional relevance of SATB1 in immune regulation and tumorigenesis.
Volume: 104
Pages: 87-93
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Publication
29306014 | -
 
First Author: Frömberg A
Year: 2018
Journal: Cancer Lett
Title: The Special AT-rich Sequence Binding Protein 1 (SATB1) and its role in solid tumors.
Volume: 417
Pages: 96-111
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Protein Domain
IPR039673 | SATB1/SATB2
Type: Family
Description: This entry includes SATB1/2 from animals. SATB1 is a global gene regulator that acts as a "docking site"for several chromatin remodeling enzymes and recruits corepressors (HDACs) or coactivators (HATs) directly to promoters []. SATB1 can bind DNA specifically to the consensus SATB1-binding sequence (CSBS) consisting of two 5'-TAATA-3' half-sites that are arranged as inverted repeats flanking a central cytosine or guanine. It can also bind DNA non-specifically []. SATB1 has been shown to bind to the nuclear matrix attachment regions (MARs) of the immunoglobulin heavy chain intronic enhancer [], while SATB2 has been shown to bind to the MARs of the endogenous immunoglobulin micro locus in pre-B cells and enhances gene expression [].SATB1 is an identified oncogene, its increased expression is associated with poor prognosis in many cancers []. Mutations in the SATB2 gene cause SATB2-associated syndrome (SAS), characterised by developmental delay/intellectual disability with absent or limited speech development, craniofacial abnormalities, behavioral problems, dysmorphic features, and palatal and dental abnormalities [, ].
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HT Experiment
GSE95832 | Assesment of DOT1L direct targets via RNAseq at E14.5 of mouse cortex
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE95833 | Assesment of Foxg1 targets via RNAseq at E13.5 of mouse cortex
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Satb2/Satb2<+>
Background: involves: 129S6/SvEvTac * C57BL/6NCrl
Zygosity: cn
Has Mutant Allele: true
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HT Experiment
GSE140822 | Astrocyte layers in the mammalian cerebral cortex revealed by a single-cell in situ transcriptomic map
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Protein
D3YZD1
Organism: Mus musculus/domesticus
Length: 154  
Fragment?: true
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Publication
25996136 | J:223290
First Author: Gil-Sanz C
Year: 2015
Journal: Neuron
Title: Lineage Tracing Using Cux2-Cre and Cux2-CreERT2 Mice.
Volume: 86
Issue: 4
Pages: 1091-1099
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Publication
28078709 | J:269911
First Author: Sweeney NT
Year: 2019
Journal: J Comp Neurol
Title: Expression of transcription factors divides retinal ganglion cells into distinct classes.
Volume: 527
Issue: 1
Pages: 225-235
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Publication
25972180 | J:221635
First Author: Cánovas J
Year: 2015
Journal: J Neurosci
Title: The Specification of Cortical Subcerebral Projection Neurons Depends on the Direct Repression of TBR1 by CTIP1/BCL11a.
Volume: 35
Issue: 19
Pages: 7552-64
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Publication
32383444 | J:344051
First Author: Grady F
Year: 2020
Journal: Cereb Cortex
Title: Direct Parabrachial-Cortical Connectivity.
Volume: 30
Issue: 9
Pages: 4811-4833
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Publication
21865449 | J:176238
First Author: Loy B
Year: 2011
Journal: J Neurosci
Title: p38α and p38β mitogen-activated protein kinases determine cholinergic transdifferentiation of sympathetic neurons.
Volume: 31
Issue: 34
Pages: 12059-67
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Publication
30692273 | J:291295
 
First Author: Addison WN
Year: 2019
Journal: Mol Cell Biol
Title: Zfp423 Regulates Skeletal Muscle Regeneration and Proliferation.
Volume: 39
Issue: 8
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Publication
28576771 | J:242900
First Author: Feng J
Year: 2017
Journal: Development
Title: BMP signaling orchestrates a transcriptional network to control the fate of mesenchymal stem cells in mice.
Volume: 144
Issue: 14
Pages: 2560-2569
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Publication
26234885 | J:252602
First Author: Tantirigama ML
Year: 2016
Journal: J Comp Neurol
Title: Fezf2 expression in layer 5 projection neurons of mature mouse motor cortex.
Volume: 524
Issue: 4
Pages: 829-45
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Publication
21068336 | J:166448
First Author: Carcea I
Year: 2010
Journal: J Neurosci
Title: Flotillin-mediated endocytic events dictate cell type-specific responses to semaphorin 3A.
Volume: 30
Issue: 45
Pages: 15317-29
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Publication
32312821 | J:289856
First Author: Paolino A
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Differential timing of a conserved transcriptional network underlies divergent cortical projection routes across mammalian brain evolution.
Volume: 117
Issue: 19
Pages: 10554-10564
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Publication
33168583 | J:301043
 
First Author: Paraíso-Luna J
Year: 2020
Journal: Development
Title: Endocannabinoid signalling in stem cells and cerebral organoids drives differentiation to deep layer projection neurons via CB1 receptors.
Volume: 147
Issue: 24
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Publication
30377226 | J:269694
First Author: Dhande OS
Year: 2019
Journal: J Neurosci
Title: Molecular Fingerprinting of On-Off Direction-Selective Retinal Ganglion Cells Across Species and Relevance to Primate Visual Circuits.
Volume: 39
Issue: 1
Pages: 78-95
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Protein
Q60611
Organism: Mus musculus/domesticus
Length: 764  
Fragment?: false
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Protein
E9PVB7
Organism: Mus musculus/domesticus
Length: 795  
Fragment?: false
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Protein
H3BKH3
Organism: Mus musculus/domesticus
Length: 615  
Fragment?: false
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Publication
28228269 | J:247473
First Author: Martersteck EM
Year: 2017
Journal: Cell Rep
Title: Diverse Central Projection Patterns of Retinal Ganglion Cells.
Volume: 18
Issue: 8
Pages: 2058-2072
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Publication
36774552 | J:337820
First Author: Wang Q
Year: 2023
Journal: Cell Rep
Title: Regional and cell-type-specific afferent and efferent projections of the mouse claustrum.
Volume: 42
Issue: 2
Pages: 112118
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Publication
29043563 | J:284637
First Author: Cuoco JA
Year: 2018
Journal: Cerebellum
Title: Malformation of the Posterior Cerebellar Vermis Is a Common Neuroanatomical Phenotype of Genetically Engineered Mice on the C57BL/6 Background.
Volume: 17
Issue: 2
Pages: 173-190
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Publication
25071457 | J:220523
 
First Author: Harris JA
Year: 2014
Journal: Front Neural Circuits
Title: Anatomical characterization of Cre driver mice for neural circuit mapping and manipulation.
Volume: 8
Pages: 76
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Publication
- | J:100256
     
First Author: The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY)
Year: 2005
Journal: Database Download
Title: MGI download of GENSAT transgene data
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Publication
21183079 | J:292518
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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