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Search results 301 to 347 out of 347 for Cgas

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Type

Details

Score

Publication

38421872 | J:346158

First Author:	Chu L
Year:	2024
Journal:	Cell Rep
Title:	HERC5-catalyzed ISGylation potentiates cGAS-mediated innate immunity.
Volume:	43
Issue:	3
Pages:	113870

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Publication

25774715 | J:231714

First Author:	Man SM
Year:	2015
Journal:	Nat Immunol
Title:	The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection.
Volume:	16
Issue:	5
Pages:	467-75

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Publication

29268096 | J:256108

First Author:	Mathur V
Year:	2017
Journal:	Neuron
Title:	Activation of the STING-Dependent Type I Interferon Response Reduces Microglial Reactivity and Neuroinflammation.
Volume:	96
Issue:	6
Pages:	1290-1302.e6

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Publication

34142428 | J:319426

First Author:	Chauveau L
Year:	2021
Journal:	EMBO Rep
Title:	Inclusion of cGAMP within virus-like particle vaccines enhances their immunogenicity.
Volume:	22
Issue:	8
Pages:	e52447

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Publication

33338425 | J:300351

First Author:	Lu C
Year:	2021
Journal:	Cancer Cell
Title:	DNA Sensing in Mismatch Repair-Deficient Tumor Cells Is Essential for Anti-tumor Immunity.
Volume:	39
Issue:	1
Pages:	96-108.e6

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Publication

- | J:341798

First Author:	Lin M
Year:	2023
Journal:	Nat Cardiovasc Res
Title:	MCM8-mediated mitophagy protects vascular health in response to nitric oxide signaling in a mouse model of Kawasaki disease.
Volume:	2
Issue:	8
Pages:	778-792

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Publication

35675783 | J:326054

First Author:	Cai X
Year:	2022
Journal:	Cell Rep
Title:	Opposing effects of deubiquitinase OTUD3 in innate immunity against RNA and DNA viruses.
Volume:	39
Issue:	10
Pages:	110920

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Publication

28598415 | J:251687

First Author:	Vanpouille-Box C
Year:	2017
Journal:	Nat Commun
Title:	DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity.
Volume:	8

Pages:	15618

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Publication

37237031 | J:339387

First Author:	Chen YH
Year:	2023
Journal:	Nat Commun
Title:	TRABID inhibition activates cGAS/STING-mediated anti-tumor immunity through mitosis and autophagy dysregulation.
Volume:	14
Issue:	1
Pages:	3050

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Publication

27264171 | J:238160

First Author:	Andrade WA
Year:	2016
Journal:	Cell Rep
Title:	Type I Interferon Induction by Neisseria gonorrhoeae: Dual Requirement of Cyclic GMP-AMP Synthase and Toll-like Receptor 4.
Volume:	15
Issue:	11
Pages:	2438-48

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Publication

29472455 | J:260491

First Author:	McArthur K
Year:	2018
Journal:	Science
Title:	BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis.
Volume:	359
Issue:	6378

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Publication

30332631 | J:277995

First Author:	Marcus A
Year:	2018
Journal:	Immunity
Title:	Tumor-Derived cGAMP Triggers a STING-Mediated Interferon Response in Non-tumor Cells to Activate the NK Cell Response.
Volume:	49
Issue:	4
Pages:	754-763.e4

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Publication

29653696 | J:272659

First Author:	Wang C
Year:	2018
Journal:	Immunity
Title:	Manganese Increases the Sensitivity of the cGAS-STING Pathway for Double-Stranded DNA and Is Required for the Host Defense against DNA Viruses.
Volume:	48
Issue:	4
Pages:	675-687.e7

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Publication

32182222 | J:300625

First Author:	Jauhari A
Year:	2020
Journal:	J Clin Invest
Title:	Melatonin inhibits cytosolic mitochondrial DNA-induced neuroinflammatory signaling in accelerated aging and neurodegeneration.
Volume:	130
Issue:	6
Pages:	3124-3136

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Publication

34901991 | J:320021

First Author:	Li T
Year:	2022
Journal:	J Exp Med
Title:	TBK1 recruitment to STING mediates autoinflammatory arthritis caused by defective DNA clearance.
Volume:	219
Issue:	1

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Publication

36346347 | J:335563

First Author:	Schumann T
Year:	2023
Journal:	J Exp Med
Title:	Deficiency for SAMHD1 activates MDA5 in a cGAS/STING-dependent manner.
Volume:	220
Issue:	1

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Protein

Q8BPK2

Organism:	Mus musculus/domesticus
Length:	400
Fragment?:	false

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Publication

31511694 | J:279972

First Author:	Luteijn RD
Year:	2019
Journal:	Nature
Title:	SLC19A1 transports immunoreactive cyclic dinucleotides.
Volume:	573
Issue:	7774
Pages:	434-438

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Publication

32404352 | J:303177

First Author:	Hoffpauir CT
Year:	2020
Journal:	J Immunol
Title:	TRIM14 Is a Key Regulator of the Type I IFN Response during Mycobacterium tuberculosis Infection.
Volume:	205
Issue:	1
Pages:	153-167

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Publication

30944173 | J:280417

First Author:	Dewi Pamungkas Putri D
Year:	2019
Journal:	J Biol Chem
Title:	PtdIns3P phosphatases MTMR3 and MTMR4 negatively regulate innate immune responses to DNA through modulating STING trafficking.
Volume:	294
Issue:	21
Pages:	8412-8423

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Publication

30777870 | J:274248

First Author:	Sen T
Year:	2019
Journal:	Cancer Discov
Title:	Targeting DNA Damage Response Promotes Antitumor Immunity through STING-Mediated T-cell Activation in Small Cell Lung Cancer.
Volume:	9
Issue:	5
Pages:	646-661

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Publication

32153571 | J:331747

First Author:	Walker MM
Year:	2020
Journal:	Front Immunol
Title:	Selective Loss of Responsiveness to Exogenous but Not Endogenous Cyclic-Dinucleotides in Mice Expressing STING-R231H.
Volume:	11

Pages:	238

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Publication

28302626 | J:263664

First Author:	Mao Y
Year:	2017
Journal:	Arterioscler Thromb Vasc Biol
Title:	STING-IRF3 Triggers Endothelial Inflammation in Response to Free Fatty Acid-Induced Mitochondrial Damage in Diet-Induced Obesity.
Volume:	37
Issue:	5
Pages:	920-929

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Publication

32715615 | J:298776

First Author:	Jena KK
Year:	2020
Journal:	EMBO Rep
Title:	Autoimmunity gene IRGM suppresses cGAS-STING and RIG-I-MAVS signaling to control interferon response.
Volume:	21
Issue:	9
Pages:	e50051

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Publication

32512189 | J:299849

First Author:	Gong Y
Year:	2020
Journal:	Biochim Biophys Acta Mol Basis Dis
Title:	Double knockout of Akt2 and AMPK accentuates high fat diet-induced cardiac anomalies through a cGAS-STING-mediated mechanism.
Volume:	1866
Issue:	10
Pages:	165855

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Publication

36256824 | J:335124

First Author:	Shi X
Year:	2022
Journal:	Proc Natl Acad Sci U S A
Title:	FLASH X-ray spares intestinal crypts from pyroptosis initiated by cGAS-STING activation upon radioimmunotherapy.
Volume:	119
Issue:	43
Pages:	e2208506119

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Publication

32581130 | J:291551

First Author:	Sharma M
Year:	2020
Journal:	Proc Natl Acad Sci U S A
Title:	Cyclic GMP-AMP synthase promotes the inflammatory and autophagy responses in Huntington disease.
Volume:	117
Issue:	27
Pages:	15989-15999

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Publication

36217001 | J:330879

First Author:	Xiong TC
Year:	2022
Journal:	Nat Commun
Title:	The E3 ubiquitin ligase ARIH1 promotes antiviral immunity and autoimmunity by inducing mono-ISGylation and oligomerization of cGAS.
Volume:	13
Issue:	1
Pages:	5973

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Publication

35634291 | J:326465

First Author:	Schubert N
Year:	2022
Journal:	Front Immunol
Title:	Genome Replication Is Associated With Release of Immunogenic DNA Waste.
Volume:	13

Pages:	880413

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Publication

25642965 | J:220373

First Author:	West AP
Year:	2015
Journal:	Nature
Title:	Mitochondrial DNA stress primes the antiviral innate immune response.
Volume:	520
Issue:	7548
Pages:	553-7

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Publication

32891637 | J:298086

First Author:	Liu F
Year:	2020
Journal:	J Mol Cell Cardiol
Title:	Beclin1 Haploinsufficiency accentuates second-hand smoke exposure -induced myocardial Remodeling and contractile dysfunction through a STING-mediated mechanism.
Volume:	148

Pages:	78-88

•

Publication

25730264 | J:227932

First Author:	Dey B
Year:	2015
Journal:	Nat Med
Title:	A bacterial cyclic dinucleotide activates the cytosolic surveillance pathway and mediates innate resistance to tuberculosis.
Volume:	21
Issue:	4
Pages:	401-6

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Publication

32571920 | J:291517

First Author:	Ku JWK
Year:	2020
Journal:	Proc Natl Acad Sci U S A
Title:	Bacterial-induced cell fusion is a danger signal triggering cGAS-STING pathway via micronuclei formation.
Volume:	117
Issue:	27
Pages:	15923-15934

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Publication

33243993 | J:299848

First Author:	Zhang Y
Year:	2020
Journal:	Nat Commun
Title:	β-arrestin 2 as an activator of cGAS-STING signaling and target of viral immune evasion.
Volume:	11
Issue:	1
Pages:	6000

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Publication

32826280 | J:303582

First Author:	Jing T
Year:	2020
Journal:	J Immunol
Title:	The Structural Basis of IRF-3 Activation upon Phosphorylation.
Volume:	205
Issue:	7
Pages:	1886-1896

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Publication

35705809 | J:330296

First Author:	Hong C
Year:	2022
Journal:	Nature
Title:	cGAS-STING drives the IL-6-dependent survival of chromosomally instable cancers.
Volume:	607
Issue:	7918
Pages:	366-373

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Publication

36681781 | J:332894

First Author:	Liu H
Year:	2023
Journal:	Cell Death Differ
Title:	CD-NTase family member MB21D2 promotes cGAS-mediated antiviral and antitumor immunity.


Pages:	1-13

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Publication

37597406 | J:339666

First Author:	An C
Year:	2023
Journal:	Int Immunopharmacol
Title:	IQGAP1 promotes mitochondrial damage and activation of the mtDNA sensor cGAS-STING pathway to induce endothelial cell pyroptosis leading to atherosclerosis.
Volume:	123

Pages:	110795

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Publication

37290532 | J:346045

First Author:	Luan C
Year:	2023
Journal:	J Biol Chem
Title:	PCSK9 inhibition interrupts the cross-talk between keratinocytes and macrophages and prevents UVB-induced skin damage.
Volume:	299
Issue:	7
Pages:	104895

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Publication

35438208 | J:344900

First Author:	Shi C
Year:	2022
Journal:	EMBO J
Title:	ZDHHC18 negatively regulates cGAS-mediated innate immunity through palmitoylation.
Volume:	41
Issue:	11
Pages:	e109272

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Publication

36656972 | J:337558

First Author:	Chen R
Year:	2023
Journal:	Circ Res
Title:	Mechanistic Insights of the LEMD2 p.L13R Mutation and Its Role in Cardiomyopathy.
Volume:	132
Issue:	2
Pages:	e43-e58

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Publication

28570638 | J:246603

First Author:	Webster SJ
Year:	2017
Journal:	PLoS Pathog
Title:	Detection of a microbial metabolite by STING regulates inflammasome activation in response to Chlamydia trachomatis infection.
Volume:	13
Issue:	6
Pages:	e1006383

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Publication

33827893 | J:309824

First Author:	Chen X
Year:	2021
Journal:	J Immunol
Title:	Regulation of Anion Channel LRRC8 Volume-Regulated Anion Channels in Transport of 2'3'-Cyclic GMP-AMP and Cisplatin under Steady State and Inflammation.
Volume:	206
Issue:	9
Pages:	2061-2074

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Publication

37781354 | J:341362

First Author:	Yang Y
Year:	2023
Journal:	Front Immunol
Title:	cGAS-STING signaling pathway in intestinal homeostasis and diseases.
Volume:	14

Pages:	1239142

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Publication

37600809 | J:339289

First Author:	Jin X
Year:	2023
Journal:	Front Immunol
Title:	The battle between the innate immune cGAS-STING signaling pathway and human herpesvirus infection.
Volume:	14

Pages:	1235590

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Publication

35338116 | J:322882

First Author:	Messaoud-Nacer Y
Year:	2022
Journal:	Cell Death Dis
Title:	STING agonist diABZI induces PANoptosis and DNA mediated acute respiratory distress syndrome (ARDS).
Volume:	13
Issue:	3
Pages:	269

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Publication

35604097 | J:326781

First Author:	Xu L
Year:	2022
Journal:	mBio
Title:	Salmonella Induces the cGAS-STING-Dependent Type I Interferon Response in Murine Macrophages by Triggering mtDNA Release.
Volume:	13
Issue:	3
Pages:	e0363221

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