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Search results 101 to 177 out of 177 for Kctd11

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:4420611
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1830623
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825734
Age: embryonic day 14.5
Image: euxassay_002773_01
Specimen Label: euxassay_002773_01
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4420611
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1830623
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825734
Age: embryonic day 14.5
Image: euxassay_002773_02
Specimen Label: euxassay_002773_02
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4420611
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1830623
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825734
Age: embryonic day 14.5
Image: euxassay_002773_03
Specimen Label: euxassay_002773_03
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4420611
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1830623
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825734
Age: embryonic day 14.5
Image: euxassay_002773_04
Specimen Label: euxassay_002773_04
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4420611
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1830623
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825734
Age: embryonic day 14.5
Image: euxassay_002773_05
Specimen Label: euxassay_002773_05
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4420611
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1830623
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825734
Age: embryonic day 14.5
Image: euxassay_002773_06
Specimen Label: euxassay_002773_06
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4420611
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1830623
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825734
Age: embryonic day 14.5
Image: euxassay_002773_07
Specimen Label: euxassay_002773_07
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4420611
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1830623
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825734
Age: embryonic day 14.5
Image: euxassay_002773_08
Specimen Label: euxassay_002773_08
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4420611
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1830623
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825734
Age: embryonic day 14.5
Image: euxassay_002773_09
Specimen Label: euxassay_002773_09
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4420611
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1830623
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825734
Age: embryonic day 14.5
Image: euxassay_002773_10
Specimen Label: euxassay_002773_10
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4420611
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1830623
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825734
Age: embryonic day 14.5
Image: euxassay_002773_11
Specimen Label: euxassay_002773_11
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4420611
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1830623
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825734
Age: embryonic day 14.5
Image: euxassay_002773_12
Specimen Label: euxassay_002773_12
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4420611
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1830623
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825734
Age: embryonic day 14.5
Image: euxassay_002773_13
Specimen Label: euxassay_002773_13
Detected: true
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4420611
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1830623
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825734
Age: embryonic day 14.5
Image: euxassay_002773_14
Specimen Label: euxassay_002773_14
Detected: true
Specimen Num: 14
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4420611
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1830623
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825734
Age: embryonic day 14.5
Image: euxassay_002773_15
Specimen Label: euxassay_002773_15
Detected: true
Specimen Num: 15
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4420611
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1830623
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825734
Age: embryonic day 14.5
Image: euxassay_002773_16
Specimen Label: euxassay_002773_16
Detected: true
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4420611
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1830623
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825734
Age: embryonic day 14.5
Image: euxassay_002773_17
Specimen Label: euxassay_002773_17
Detected: true
Specimen Num: 17
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4420611
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1830623
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825734
Age: embryonic day 14.5
Image: euxassay_002773_18
Specimen Label: euxassay_002773_18
Detected: true
Specimen Num: 18
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4420611
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1830623
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825734
Age: embryonic day 14.5
Image: euxassay_002773_19
Specimen Label: euxassay_002773_19
Detected: true
Specimen Num: 19
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4420611
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1830623
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825734
Age: embryonic day 14.5
Image: euxassay_002773_20
Specimen Label: euxassay_002773_20
Detected: true
Specimen Num: 20
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4420611
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1830623
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825734
Age: embryonic day 14.5
Image: euxassay_002773_21
Specimen Label: euxassay_002773_21
Detected: true
Specimen Num: 21
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4420611
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1830623
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825734
Age: embryonic day 14.5
Image: euxassay_002773_22
Specimen Label: euxassay_002773_22
Detected: true
Specimen Num: 22
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4420611
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1830623
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825734
Age: embryonic day 14.5
Image: euxassay_002773_23
Specimen Label: euxassay_002773_23
Detected: true
Specimen Num: 23
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3722678
Assay Type: RNA in situ
Annotation Date: 2007-09-25
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:1697920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:3722683
Age: embryonic day 12.5
Image: 4L
Note: Barely detectable expression in the ventricular zone.
Specimen Label: 4L
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3722678
Assay Type: RNA in situ
Annotation Date: 2007-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616414
Pattern: Not Specified
Stage: TS14
Assay Id: MGI:3722682
Age: embryonic day 9.0
Image: 4D
Specimen Label: 4D
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3722678
Assay Type: RNA in situ
Annotation Date: 2007-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616416
Pattern: Regionally restricted
Stage: TS16
Assay Id: MGI:3722682
Age: embryonic day 9.25
Image: 4F
Note: Expression is restricted to the ventro-medial region of the neural tube,
Specimen Label: 4F
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3722678
Assay Type: RNA in situ
Annotation Date: 2007-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616413
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:3722682
Age: embryonic day 8.25
Image: 4I
Note: Expression in the ventromedial region of the neural tube.
Specimen Label: 4I
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3722678
Assay Type: RNA in situ
Annotation Date: 2007-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:3722683
Age: embryonic day 10.5
Image: 4K
Note: Expression in the ventromedial region of the neural tube.
Specimen Label: 4K
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3722678
Assay Type: RNA in situ
Annotation Date: 2007-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666916
Pattern: Not Specified
Stage: TS16
Assay Id: MGI:3722682
Age: embryonic day 9.25
Image: 4F
Specimen Label: 4F
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3722678
Assay Type: RNA in situ
Annotation Date: 2007-09-25
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:1754724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:3722683
Age: embryonic day 16.5
Image: 4O
Note: Authors report barely detectable expression in the ventricular zone.
Specimen Label: 4O
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3722678
Assay Type: RNA in situ
Annotation Date: 2007-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1679724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:3722683
Age: embryonic day 16.5
Image: 4O
Specimen Label: 4O
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3722678
Assay Type: RNA in situ
Annotation Date: 2007-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614613
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:3722682
Age: embryonic day 8.25
Image: 4G
Specimen Label: 4G
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3722678
Assay Type: RNA in situ
Annotation Date: 2007-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1629013
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:3722682
Age: embryonic day 8.25
Image: 4C
Specimen Label: 4C
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3722678
Assay Type: RNA in situ
Annotation Date: 2007-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267924
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:3722683
Age: embryonic day 16.5
Image: 4N
Note: Authors report lower expression in the ventricular zone.
Specimen Label: 4N
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3722678
Assay Type: RNA in situ
Annotation Date: 2007-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1639315
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:3722682
Age: embryonic day 9.5
Image: 4H
Specimen Label: 4H
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3722678
Assay Type: RNA in situ
Annotation Date: 2007-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1654015
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:3722682
Age: embryonic day 9.5
Image: 4H
Specimen Label: 4H
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3722678
Assay Type: RNA in situ
Annotation Date: 2007-09-25
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1689424
Pattern: Diffuse
Stage: TS24
Assay Id: MGI:3722683
Age: embryonic day 16.5
Image: 4N
Note: Some low and diffuse staining is also observed in the whole brain area.
Specimen Label: 4N
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3722678
Assay Type: RNA in situ
Annotation Date: 2007-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1654317
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:3722683
Age: embryonic day 10.5
Image: 4M
Note: Expression in the olfactory placode, including the epithelium lining the olfactory placode
Specimen Label: 4M
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3722678
Assay Type: RNA in situ
Annotation Date: 2007-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1638816
Pattern: Not Specified
Stage: TS16
Assay Id: MGI:3722682
Age: embryonic day 9.25
Image: 4F
Specimen Label: 4F
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3722678
Assay Type: RNA in situ
Annotation Date: 2007-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1668017
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:3722683
Age: embryonic day 10.5
Image: 4M
Specimen Label: 4M
Detected: true
Specimen Num: 3
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Publication
38062245 | J:345824
First Author: Lospinoso Severini L
Year: 2024
Journal: Cell Death Differ
Title: SALL4 is a CRL3(REN/KCTD11) substrate that drives Sonic Hedgehog-dependent medulloblastoma.
Volume: 31
Issue: 2
Pages: 170-187
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:342601
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniPathway vocabulary mapping
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Publication
- | J:77000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
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Publication
- | J:188991
     
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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UniProt Feature
UniProt Feature
Begin: 1
Description: BTB/POZ domain-containing protein KCTD11
Type: chain
End: 232
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Protein
A0A5K1VVR8
Organism: Mus musculus/domesticus
Length: 271  
Fragment?: false
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Publication
15249678 | -
First Author: Di Marcotullio L
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma.
Volume: 101
Issue: 29
Pages: 10833-8
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Publication
21472142 | -
First Author: De Smaele E
Year: 2011
Journal: Neoplasia
Title: Identification and characterization of KCASH2 and KCASH3, 2 novel Cullin3 adaptors suppressing histone deacetylase and Hedgehog activity in medulloblastoma.
Volume: 13
Issue: 4
Pages: 374-85
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Publication
20081843 | -
First Author: Canettieri G
Year: 2010
Journal: Nat Cell Biol
Title: Histone deacetylase and Cullin3-REN(KCTD11) ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation.
Volume: 12
Issue: 2
Pages: 132-42
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Protein Domain
IPR045763 | KCTD11/21_C
Type: Domain
Description: This entry represents the C-terminal region of BTB/POZ domain-containing protein KCTD11 (the KCASH1 protein, also known as REN: EGF-, NGF- and retinoic acid-responsive gene) and its homologue, KCTD21 (the KCASH2 protein).These members of the KCASH family (KCTD containing, Cullin3 adaptor, suppressor of Hedgehog) share high similarity and a BTB domain responsible for oligomerization and formation of a Cullin3 ubiquitin ligase complex. They are specifically expressed in brain and cerebellum where they have a role in neuronal differentiation, and suppressor activity on acetylation-dependent Hedgehog/Gli signalling through ubiquitination and degradation of histone deacetylase 1 (HDAC1). These proteins have been described as tumor suppressors that inhibit medulloblastoma growth by antagonizing Hedgehog signalling [, , ].
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Protein
Q3URF8
Organism: Mus musculus/domesticus
Length: 260  
Fragment?: false
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Protein
B2RTJ2
Organism: Mus musculus/domesticus
Length: 260  
Fragment?: false
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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