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Search results 201 to 300 out of 353 for Cd207

0.038s
Type Details Score
Strain
Attribute String: targeted mutation, mutant strain, congenic
Strain
Attribute String: congenic, mutant strain, targeted mutation
Allele
Name: CD207 antigen; targeted mutation 1, Bjorn E Clausen
Allele Type: Targeted
Attribute String: Inserted expressed sequence
Strain
Attribute String: congenic, mutant strain, targeted mutation
Strain
Attribute String: targeted mutation, mutant strain, congenic
Allele
Name: CD207 antigen; targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
Allele
Name: CD207 antigen; endonuclease-mediated mutation 5, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Allele
Name: CD207 antigen; targeted mutation 1.1, Consortium for Functional Glycomics
Allele Type: Targeted
Attribute String: Null/knockout
Strain
Attribute String: congenic, mutant strain, targeted mutation
Allele
Name: CD207 antigen; targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele
Name: CD207 antigen; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
Genotype
Symbol: Cd207/Cd207
Background: B6.129S2-Cd207
Zygosity: hm
Has Mutant Allele: true
Strain
Attribute String: mutant strain, targeted mutation, congenic
Genotype
Symbol: Cd207/Cd207
Background: involves: C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Cd207/Cd207<+> Tgfbr1/Tgfbr1
Background: involves: 129S4/SvJaeSor * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Braf/Braf Cd207/Cd207<+>
Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd207/Cd207
Background: involves: 129S2/SvPas
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Cd207/Cd207<+>
Background: involves: C57BL/6 * SJL
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Cd207/Cd207<+>
Background: involves: C57BL/6
Zygosity: ht
Has Mutant Allele: true
Allele
Name: transgene insertion, Daniel H Kaplan
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Allele
Name: transgene insertion 312, Daniel H Kaplan
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Publication
First Author: Flamar AL
Year: 2012
Journal: J Immunol
Title: Noncovalent assembly of anti-dendritic cell antibodies and antigens for evoking immune responses in vitro and in vivo.
Volume: 189
Issue: 5
Pages: 2645-55
Allele
Name: transgene insertion 1, Daniel H Kaplan
Allele Type: Transgenic
Attribute String: Recombinase
Publication
First Author: Bobr A
Year: 2010
Journal: J Immunol
Title: Acute ablation of Langerhans cells enhances skin immune responses.
Volume: 185
Issue: 8
Pages: 4724-8
Strain
Attribute String: coisogenic, mutant strain, transgenic
Strain
Attribute String: congenic, mutant strain, transgenic
Publication
First Author: Obhrai JS
Year: 2008
Journal: J Invest Dermatol
Title: Langerhans cells are not required for efficient skin graft rejection.
Volume: 128
Issue: 8
Pages: 1950-5
Publication
First Author: Su Q
Year: 2020
Journal: PLoS One
Title: Brief communication: Long-term absence of Langerhans cells alters the gene expression profile of keratinocytes and dendritic epidermal T cells.
Volume: 15
Issue: 1
Pages: e0223397
Genotype
Symbol: Tg(CD207-Dta)312Dhka/?
Background: FVB-Tg(CD207-Dta)312Dhka
Zygosity: ot
Has Mutant Allele: true
Publication
First Author: Kaplan DH
Year: 2005
Journal: Immunity
Title: Epidermal langerhans cell-deficient mice develop enhanced contact hypersensitivity.
Volume: 23
Issue: 6
Pages: 611-20
Publication
First Author: Lewis JM
Year: 2015
Journal: J Invest Dermatol
Title: Langerhans Cells Facilitate UVB-Induced Epidermal Carcinogenesis.
Volume: 135
Issue: 11
Pages: 2824-2833
Publication
First Author: Lewis JM
Year: 2015
Journal: J Invest Dermatol
Title: Mechanisms of chemical cooperative carcinogenesis by epidermal Langerhans cells.
Volume: 135
Issue: 5
Pages: 1405-1414
Strain
Attribute String: Not specified
Publication      
First Author: Tanaka R
Year: 2022
Journal: J Invest Dermatol
Title: The Role of PD-L1 on Langerhans Cells in the Regulation of Psoriasis.
Genotype
Symbol: Flg/Flg Tg(CD207-Dta)312Dhka/?
Background: involves: 129S6/SvEvTac * BALB/c * C57BL/6NTac * FVB
Zygosity: cx
Has Mutant Allele: true
Publication
First Author: Scholz F
Year: 2014
Journal: PLoS One
Title: Immune mediated shaping of microflora community composition depends on barrier site.
Volume: 9
Issue: 1
Pages: e84019
Publication
First Author: Modi BG
Year: 2012
Journal: Science
Title: Langerhans cells facilitate epithelial DNA damage and squamous cell carcinoma.
Volume: 335
Issue: 6064
Pages: 104-8
Publication
First Author: Stoitzner P
Year: 2005
Journal: Eur J Cell Biol
Title: Langerhans cells are strongly reduced in the skin of transgenic mice overexpressing follistatin in the epidermis.
Volume: 84
Issue: 8
Pages: 733-41
Publication
First Author: Li H
Year: 2011
Journal: Blood
Title: Langerhans cells are not required for graft-versus-host disease.
Volume: 117
Issue: 2
Pages: 697-707
Publication  
First Author: Matsumoto R
Year: 2018
Journal: JCI Insight
Title: Epithelial TRAF6 drives IL-17-mediated psoriatic inflammation.
Volume: 3
Issue: 15
Genotype
Symbol: B9d2/Tgfb1/B9d2/Tgfb1 Tg(CD207-cre)1Dhka/?
Background: involves: 129S6/SvEvTac * C57BL/6J * SJL/J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: B9d2/Tgfb1/B9d2/Tgfb1 Tg(CD207-cre)1Dhka/?
Background: involves: 129S6/SvEvTac * C57BL/6J * SJL/J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: B9d2/Tgfb1/B9d2<+> Tg(CD207-cre)1Dhka/?
Background: involves: 129S6/SvEvTac * C57BL/6J * SJL/J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tgfbr2/Tgfbr2 Tg(CD207-cre)1Dhka/?
Background: involves: 129S6/SvEvTac * C57BL/6J * SJL/J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Epcam/Epcam Tg(CD207-cre)1Dhka/?
Background: involves: 129 * C57BL/6 * C57BL/6J * SJL/J
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Tassi I
Year: 2015
Journal: Eur J Immunol
Title: The NF-κB regulator Bcl-3 modulates inflammation during contact hypersensitivity reactions in radioresistant cells.
Volume: 45
Issue: 4
Pages: 1059-1068
Publication
First Author: Su Q
Year: 2019
Journal: J Invest Dermatol
Title: Keratinocytes Share Gene Expression Fingerprint with Epidermal Langerhans Cells via mRNA Transfer.
Volume: 139
Issue: 11
Pages: 2313-2323.e8
Publication
First Author: Ouchi T
Year: 2016
Journal: J Invest Dermatol
Title: EpCAM Expressed by Murine Epidermal Langerhans Cells Modulates Immunization to an Epicutaneously Applied Protein Antigen.
Volume: 136
Issue: 8
Pages: 1627-35
Publication
First Author: Greter M
Year: 2012
Journal: Immunity
Title: Stroma-derived interleukin-34 controls the development and maintenance of langerhans cells and the maintenance of microglia.
Volume: 37
Issue: 6
Pages: 1050-1060
Publication
First Author: Haley K
Year: 2012
Journal: J Immunol
Title: Langerhans cells require MyD88-dependent signals for Candida albicans response but not for contact hypersensitivity or migration.
Volume: 188
Issue: 9
Pages: 4334-9
Publication  
First Author: Huang L
Year: 2020
Journal: Front Immunol
Title: Smad2/4 Signaling Pathway Is Critical for Epidermal Langerhans Cell Repopulation Under Inflammatory Condition but Not Required for Their Homeostasis at Steady State.
Volume: 11
Pages: 912
Genotype
Symbol: Tgfb1/B9d2/Tgfb1 Tg(CD207-cre)1Dhka/?
Background: involves: 129S6/SvEvTac * C57BL/6J * SJL/J
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Igyarto BZ
Year: 2009
Journal: J Immunol
Title: Langerhans cells suppress contact hypersensitivity responses via cognate CD4 interaction and langerhans cell-derived IL-10.
Volume: 183
Issue: 8
Pages: 5085-93
Publication
First Author: Gaiser MR
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Cancer-associated epithelial cell adhesion molecule (EpCAM; CD326) enables epidermal Langerhans cell motility and migration in vivo.
Volume: 109
Issue: 15
Pages: E889-97
Publication
First Author: Hurabielle C
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Immunity to commensal skin fungi promotes psoriasiform skin inflammation.
Volume: 117
Issue: 28
Pages: 16465-16474
Publication
First Author: Kaplan DH
Year: 2007
Journal: J Exp Med
Title: Autocrine/paracrine TGFbeta1 is required for the development of epidermal Langerhans cells.
Volume: 204
Issue: 11
Pages: 2545-52
Publication
First Author: Nelson DS
Year: 2019
Journal: PLoS One
Title: BRAF V600E and Pten deletion in mice produces a histiocytic disorder with features of Langerhans cell histiocytosis.
Volume: 14
Issue: 9
Pages: e0222400
Publication
First Author: Kobayashi T
Year: 2015
Journal: Immunity
Title: Dysbiosis and Staphylococcus aureus Colonization Drives Inflammation in Atopic Dermatitis.
Volume: 42
Issue: 4
Pages: 756-66
Publication
First Author: Liang J
Year: 2016
Journal: Cell Rep
Title: Inflammatory Th1 and Th17 in the Intestine Are Each Driven by Functionally Specialized Dendritic Cells with Distinct Requirements for MyD88.
Volume: 17
Issue: 5
Pages: 1330-1343
Publication
First Author: Wasko R
Year: 2022
Journal: Dev Cell
Title: Langerhans cells are essential components of the angiogenic niche during murine skin repair.
Volume: 57
Issue: 24
Pages: 2699-2713.e5
Publication
First Author: Sun T
Year: 2017
Journal: Mucosal Immunol
Title: Intestinal Batf3-dependent dendritic cells are required for optimal antiviral T-cell responses in adult and neonatal mice.
Volume: 10
Issue: 3
Pages: 775-788
Publication
First Author: Yang Y
Year: 2019
Journal: J Dermatol Sci
Title: Keratinocyte-derived TGFβ is not required to maintain skin immune homeostasis.
Volume: 94
Issue: 2
Pages: 290-297
Publication      
First Author: Ndeupen S
Year: 2021
Journal: bioRxiv
Title: Langerhans cells and cDC1s play redundant roles in mRNA-LNP induced protective anti-influenza and anti-SARS-CoV-2 responses.
Publication
First Author: Wong E
Year: 2019
Journal: Cell Rep
Title: Langerhans Cells Orchestrate the Protective Antiviral Innate Immune Response in the Lymph Node.
Volume: 29
Issue: 10
Pages: 3047-3059.e3
Publication
First Author: Guo Y
Year: 2004
Journal: Nat Struct Mol Biol
Title: Structural basis for distinct ligand-binding and targeting properties of the receptors DC-SIGN and DC-SIGNR.
Volume: 11
Issue: 7
Pages: 591-8
Publication
First Author: Feinberg H
Year: 2005
Journal: J Biol Chem
Title: Extended neck regions stabilize tetramers of the receptors DC-SIGN and DC-SIGNR.
Volume: 280
Issue: 2
Pages: 1327-35
Publication
First Author: Valladeau J
Year: 2003
Journal: Immunol Res
Title: Langerin/CD207 sheds light on formation of birbeck granules and their possible function in Langerhans cells.
Volume: 28
Issue: 2
Pages: 93-107
Publication
First Author: Mummidi S
Year: 2001
Journal: J Biol Chem
Title: Extensive repertoire of membrane-bound and soluble dendritic cell-specific ICAM-3-grabbing nonintegrin 1 (DC-SIGN1) and DC-SIGN2 isoforms. Inter-individual variation in expression of DC-SIGN transcripts.
Volume: 276
Issue: 35
Pages: 33196-212
Publication
First Author: Stambach NS
Year: 2003
Journal: Glycobiology
Title: Characterization of carbohydrate recognition by langerin, a C-type lectin of Langerhans cells.
Volume: 13
Issue: 5
Pages: 401-10
Publication
First Author: Massarelli I
Year: 2010
Journal: Int J Mol Sci
Title: Three-dimensional models of the oligomeric human asialoglycoprotein receptor (ASGP-R).
Volume: 11
Issue: 10
Pages: 3867-84
Publication
First Author: Park EI
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: The asialoglycoprotein receptor clears glycoconjugates terminating with sialic acid alpha 2,6GalNAc.
Volume: 102
Issue: 47
Pages: 17125-9
Protein Domain
Type: Domain
Description: This entry represents the C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN), also known as CD209 antigen, and the related receptor, DC-SIGN receptor (DC-SIGNR), also known as CD209 antigen-like protein 1 or C-type lectin domain family 4 member M. This group also contains proteins similar to hepatic asialoglycoprotein receptor (ASGP-R) and langerin (also known as CD207 or C-type lectin domain family 4 member K) in human. These proteins are type II membrane proteins with a CTLD ectodomain. CTLD refers to a domain homologous to the carbohydrate-recognition domains (CRDs) of the C-type lectins [].DC-SIGN is thought to mediate the initial contact between dendritic cells and resting T cells, and may also mediate the rolling of DCs on epithelium []. DC-SIGN and DC-SIGNR bind to oligosaccharides present on human tissues, as well as on pathogens including parasites, bacteria, and viruses. DC-SIGN and DC-SIGNR bind to HIV, enhancing viral infection of T cells []. DC-SIGN and DC-SIGNR are homotetrameric, and contain four CTLDs stabilized by a coiled coil of alpha helices []. The hepatic ASGP-R is an endocytic recycling receptor which binds and internalizes desialylated glycoproteins having a terminal galactose or N-acetylgalactosamine residues on their N-linked carbohydrate chains, via the clathrin-coated pit mediated endocytic pathway, and delivers them to lysosomes for degradation. It has been proposed that glycoproteins bearing terminals 'Sia (sialic acid) alpha2, 6GalNAc' and 'Sia alpha2, 6Gal' are endogenous ligands for ASGP-R, and that ASGP-R participates in regulating the relative concentration of serum glycoproteins bearing alpha 2,6-linked Sia []. The human ASGP-R is a hetero-oligomer composed of two subunits, both of which are found within this group []. Langerin is expressed in a subset of dendritic leukocytes, the Langerhans cells (LC). Langerin induces the formation of Birbeck Granules (BGs) and associates with these BGs following internalization []. Langerin binds, in a calcium-dependent manner, to glyco-conjugates containing mannose and related sugars mediating their uptake and degradation. Langerin molecules oligomerize as trimers with three CTLDs held together by a coiled-coil of alpha helices [].
Publication
First Author: Tamoutounour S
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Keratinocyte-intrinsic MHCII expression controls microbiota-induced Th1 cell responses.
Volume: 116
Issue: 47
Pages: 23643-23652
Publication  
First Author: Lewis JM
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Chronic UV radiation-induced RORγt+ IL-22-producing lymphoid cells are associated with mutant KC clonal expansion.
Volume: 118
Issue: 37
Publication
First Author: Kashem SW
Year: 2015
Journal: Immunity
Title: Nociceptive Sensory Fibers Drive Interleukin-23 Production from CD301b+ Dermal Dendritic Cells and Drive Protective Cutaneous Immunity.
Volume: 43
Issue: 3
Pages: 515-26
Publication
First Author: Strid J
Year: 2011
Journal: Science
Title: The intraepithelial T cell response to NKG2D-ligands links lymphoid stress surveillance to atopy.
Volume: 334
Issue: 6060
Pages: 1293-7
Publication
First Author: Panea C
Year: 2015
Journal: Cell Rep
Title: Intestinal Monocyte-Derived Macrophages Control Commensal-Specific Th17 Responses.
Volume: 12
Issue: 8
Pages: 1314-24
Publication  
First Author: Shipman WD
Year: 2018
Journal: Sci Transl Med
Title: A protective Langerhans cell-keratinocyte axis that is dysfunctional in photosensitivity.
Volume: 10
Issue: 454
Publication
First Author: Kim TG
Year: 2015
Journal: J Allergy Clin Immunol
Title: CCCTC-binding factor controls the homeostatic maintenance and migration of Langerhans cells.
Volume: 136
Issue: 3
Pages: 713-24
Publication
First Author: Mohammed J
Year: 2016
Journal: Nat Immunol
Title: Stromal cells control the epithelial residence of DCs and memory T cells by regulated activation of TGF-β.
Volume: 17
Issue: 4
Pages: 414-21
Publication
First Author: Russler-Germain EV
Year: 2021
Journal: Immunity
Title: Commensal Cryptosporidium colonization elicits a cDC1-dependent Th1 response that promotes intestinal homeostasis and limits other infections.
Volume: 54
Issue: 11
Pages: 2547-2564.e7
Publication
First Author: McKenzie DR
Year: 2022
Journal: Nat Immunol
Title: Normality sensing licenses local T cells for innate-like tissue surveillance.
Volume: 23
Issue: 3
Pages: 411-422
Publication
First Author: Hirai T
Year: 2019
Journal: Immunity
Title: Keratinocyte-Mediated Activation of the Cytokine TGF-β Maintains Skin Recirculating Memory CD8+ T Cells.
Volume: 50
Issue: 5
Pages: 1249-1261.e5
Publication
First Author: Crawford G
Year: 2018
Journal: Nat Immunol
Title: Epithelial damage and tissue γδ T cells promote a unique tumor-protective IgE response.
Volume: 19
Issue: 8
Pages: 859-870
Publication
First Author: Gerner MY
Year: 2012
Journal: Immunity
Title: Histo-cytometry: a method for highly multiplex quantitative tissue imaging analysis applied to dendritic cell subset microanatomy in lymph nodes.
Volume: 37
Issue: 2
Pages: 364-76
Publication
First Author: Bell BD
Year: 2013
Journal: Nat Immunol
Title: The transcription factor STAT5 is critical in dendritic cells for the development of TH2 but not TH1 responses.
Volume: 14
Issue: 4
Pages: 364-71
Publication
First Author: Zhang S
Year: 2021
Journal: Cell
Title: Nonpeptidergic neurons suppress mast cells via glutamate to maintain skin homeostasis.
Volume: 184
Issue: 8
Pages: 2151-2166.e16
Publication
First Author: Malhotra D
Year: 2016
Journal: Nat Immunol
Title: Tolerance is established in polyclonal CD4(+) T cells by distinct mechanisms, according to self-peptide expression patterns.
Volume: 17
Issue: 2
Pages: 187-95
Protein
Organism: Mus musculus/domesticus
Length: 219  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 219  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 218  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 308  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 245  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 178  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 301  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 325  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 237  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 238  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 742  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 331  
Fragment?: false