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Search results 601 to 700 out of 713 for Ror2

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Type Details Score
Publication
25826454 | J:229257
First Author: Gu Z
Year: 2015
Journal: PLoS One
Title: Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.
Volume: 10
Issue: 3
Pages: e0121550
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Publication
28705898 | J:243411
First Author: Rutledge EA
Year: 2017
Journal: Development
Title: Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development.
Volume: 144
Issue: 17
Pages: 3177-3188
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Publication
11114734 | J:66153
First Author: Robinson DR
Year: 2000
Journal: Oncogene
Title: The protein tyrosine kinase family of the human genome.
Volume: 19
Issue: 49
Pages: 5548-57
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
19521566 | J:177549
First Author: Willnow T
Year: 2005
Journal: Organogenesis
Title: The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.
Volume: 2
Issue: 2
Pages: 42-7
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Publication
- | J:165964
     
First Author: Mammalian Functional Genomics Centre
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the NorCOMM project by the Mammalian Functional Genomics Centre (Mfgc), University of Manitoba
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Publication
- | J:345476
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2023
Title: TreeGrafter-generated GO annotations
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:72247
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein
Q8C3W2
Organism: Mus musculus/domesticus
Length: 944  
Fragment?: false
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Protein
E9PUN5
Organism: Mus musculus/domesticus
Length: 932  
Fragment?: false
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Pathway
R-MMU-5140745 | WNT5A-dependent internalization of FZD2, FZD5 and ROR2
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Publication
18667433 | -
First Author: Nomachi A
Year: 2008
Journal: J Biol Chem
Title: Receptor tyrosine kinase Ror2 mediates Wnt5a-induced polarized cell migration by activating c-Jun N-terminal kinase via actin-binding protein filamin A.
Volume: 283
Issue: 41
Pages: 27973-81
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Interaction Experiment
Oishi I (2003)
Description: The receptor tyrosine kinase Ror2 is involved in non-canonical Wnt5a/JNK signalling pathway.
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Interaction Experiment
Matsuda T (2003)
Description: The receptor tyrosine kinase Ror2 associates with the melanoma-associated antigen (MAGE) family protein Dlxin-1 and regulates its intracellular distribution.
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HT Experiment
GSE161395 | Ror2-mediated non-canonical Wnt signaling regulates Cdc42 and cell proliferation during root development
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Protein
Q9Z139
Organism: Mus musculus/domesticus
Length: 937  
Fragment?: false
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Publication
12754255 | -
First Author: Matsuda T
Year: 2003
Journal: J Biol Chem
Title: The receptor tyrosine kinase Ror2 associates with the melanoma-associated antigen (MAGE) family protein Dlxin-1 and regulates its intracellular distribution.
Volume: 278
Issue: 31
Pages: 29057-64
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Protein Coding Gene
MGI:1347520 | Ror1
Type: protein_coding_gene
Organism: mouse, laboratory
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Genotype
Genotype
Symbol: Ror2/Ror2<+>
Background: B6.129S1-Ror2
Zygosity: ht
Has Mutant Allele: true
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DO Term
DOID:0110969 | brachydactyly type B1
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Allele
Ror2<tm1Anec> | MGI:3793279
 
Name: receptor tyrosine kinase-like orphan receptor 2; targeted mutation 1, Aris N Economides
Allele Type: Targeted
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Allele
Ror2<tm1Ymi> | MGI:2183225
Name: receptor tyrosine kinase-like orphan receptor 2; targeted mutation 1, Yasuhiro Minami
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Prickle1<tm1Asw> | MGI:5645929
Name: prickle planar cell polarity protein 1; targeted mutation 1, Anand Swaroop
Allele Type: Targeted
Attribute String: Hypomorph, Reporter
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Publication
25835638 | -
First Author: Shabani M
Year: 2015
Journal: Expert Opin Ther Targets
Title: Receptor tyrosine kinase-like orphan receptor 1: a novel target for cancer immunotherapy.
Volume: 19
Issue: 7
Pages: 941-55
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Publication
21487037 | -
First Author: Gentile A
Year: 2011
Journal: Cancer Res
Title: Ror1 is a pseudokinase that is crucial for Met-driven tumorigenesis.
Volume: 71
Issue: 8
Pages: 3132-41
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Protein Domain
IPR016247 | Tyr_kinase_rcpt_ROR
Type: Family
Description: The Ror family of receptor tyrosine kinases consists of two structurally related proteins, Ror1 and Ror2. Ror1 is a pseudokinase that acts as a substrate for the oncogenic tyrosine kinase Met []. It is expressed during development []. It shows no significant expression in normal adult tissues, but it is selectively overexpressed in a number of malignancies []. Ror2 functions as a Wnt receptor required to maintain basal NMDAR-mediated synaptic transmission []. For a time its ligand remained elusive, hence the name receptor tyrosine kinase-like orphan receptor-2 (Ror2). It is now established that Wnt5A acts a ligand for Ror2 [].
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Genotype
Genotype
Symbol: Ror2/Ror2
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ror2/Ror2
Background: B6.129S1-Ror2
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prickle1/Prickle1
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prickle1/Prickle1
Background: Not Specified
Zygosity: ht
Has Mutant Allele: true
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DO Term
DOID:0060764 | autosomal recessive Robinow syndrome
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Protein Coding Gene
MGI:108571 | Fzd5
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1888513 | Fzd2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1921575 | Cltb
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:98958 | Wnt5a
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q9JIP6
Organism: Mus musculus/domesticus
Length: 570  
Fragment?: false
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Protein
Q9EQD0
Organism: Mus musculus/domesticus
Length: 585  
Fragment?: false
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Protein
Q6IRU5
Organism: Mus musculus/domesticus
Length: 229  
Fragment?: false
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Protein
P22725
Organism: Mus musculus/domesticus
Length: 380  
Fragment?: false
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Protein Coding Gene
MGI:1916034 | Prickle1
Type: protein_coding_gene
Organism: mouse, laboratory
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HT Experiment
GSE140779 | A mammalian Wnt5a-Ror2-angl2 axis controls the cytoskeleton and confers cellular properties required for alveologenesis
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
17942487 | -
First Author: Green JL
Year: 2007
Journal: Development
Title: The C. elegans ROR receptor tyrosine kinase, CAM-1, non-autonomously inhibits the Wnt pathway.
Volume: 134
Issue: 22
Pages: 4053-62
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Publication
18848778 | -
First Author: Green JL
Year: 2008
Journal: Trends Cell Biol
Title: Ror receptor tyrosine kinases: orphans no more.
Volume: 18
Issue: 11
Pages: 536-44
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Protein Domain
IPR041775 | Ror-like_CRD
Type: Domain
Description: The cysteine-rich domain (CRD) is an essential part of the tyrosine kinase-like orphan receptor (Ror) proteins, a conserved family of tyrosine kinases that function in various processes, including neuronal and skeletal development, cell polarity, and cell movement. Ror proteins are receptors of Wnt proteins, which are key players in a number of fundamental cellular processes in embryogenesis and postnatal development. In different cellular contexts, Ror proteins can either activate or repress transcription of Wnt target genes, and can modulate Wnt signaling by sequestering Wnt ligands. In addition, a number of Wnt-independent functions have been proposed for both Ror1 and Ror2 []. Proteins containing this domain also include CAM-1 from C. elegans. CAM-1 is a ROR receptor tyrosine kinase that inhibits the Wnt pathway [].
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Protein Coding Gene
MGI:1919020 | Ap2b1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2388633 | Cltc
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1298405 | Ap2m1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:894297 | Clta
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2141861 | Ap2s1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:101921 | Ap2a1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:101920 | Ap2a2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P17427
Organism: Mus musculus/domesticus
Length: 938  
Fragment?: false
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Protein
P17426
Organism: Mus musculus/domesticus
Length: 977  
Fragment?: false
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Protein
Q9DBG3
Organism: Mus musculus/domesticus
Length: 937  
Fragment?: false
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Protein
P62743
Organism: Mus musculus/domesticus
Length: 142  
Fragment?: false
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Protein
P84091
Organism: Mus musculus/domesticus
Length: 435  
Fragment?: false
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Protein
Q68FD5
Organism: Mus musculus/domesticus
Length: 1675  
Fragment?: false
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Protein
O08585
Organism: Mus musculus/domesticus
Length: 235  
Fragment?: false
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Publication
20593419 | J:161784
First Author: Lyashenko N
Year: 2010
Journal: Dev Dyn
Title: Mice lacking the orphan receptor ror1 have distinct skeletal abnormalities and are growth retarded.
Volume: 239
Issue: 8
Pages: 2266-77
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Publication
31246175 | J:288971
   
First Author: Carvalho JR
Year: 2019
Journal: Elife
Title: Non-canonical Wnt signaling regulates junctional mechanocoupling during angiogenic collective cell migration.
Volume: 8
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Publication
23019370 | J:190318
First Author: Goh KY
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: p21-activated kinase interacts with Wnt signaling to regulate tissue polarity and gene expression.
Volume: 109
Issue: 39
Pages: 15853-8
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Publication
22438823 | J:183479
First Author: Chen L
Year: 2012
Journal: PLoS Genet
Title: Transcriptional control in cardiac progenitors: Tbx1 interacts with the BAF chromatin remodeling complex and regulates Wnt5a.
Volume: 8
Issue: 3
Pages: e1002571
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Publication
28851822 | J:259520
 
First Author: Uehara S
Year: 2017
Journal: Sci Signal
Title: Protein kinase N3 promotes bone resorption by osteoclasts in response to Wnt5a-Ror2 signaling.
Volume: 10
Issue: 494
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Publication
19910923 | J:156508
First Author: Sato A
Year: 2010
Journal: EMBO J
Title: Wnt5a regulates distinct signalling pathways by binding to Frizzled2.
Volume: 29
Issue: 1
Pages: 41-54
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Publication
28790171 | J:245972
First Author: Kamizaki K
Year: 2017
Journal: J Biol Chem
Title: The Ror1 receptor tyrosine kinase plays a critical role in regulating satellite cell proliferation during regeneration of injured muscle.
Volume: 292
Issue: 38
Pages: 15939-15951
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Publication
10932186 | J:63885
First Author: Afzal AR
Year: 2000
Journal: Nat Genet
Title: Recessive Robinow syndrome, allelic to dominant brachydactyly type B, is caused by mutation of ROR2.
Volume: 25
Issue: 4
Pages: 419-22
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Publication
22691362 | J:187512
First Author: Bakker ER
Year: 2012
Journal: Dev Biol
Title: Induced Wnt5a expression perturbs embryonic outgrowth and intestinal elongation, but is well-tolerated in adult mice.
Volume: 369
Issue: 1
Pages: 91-100
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Publication
28674110 | J:266907
First Author: Yu B
Year: 2017
Journal: Circulation
Title: A Cytokine-Like Protein Dickkopf-Related Protein 3 Is Atheroprotective.
Volume: 136
Issue: 11
Pages: 1022-1036
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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