Type |
Details |
Score |
Publication |
First Author: |
Lin J |
Year: |
2016 |
Journal: |
Sci Rep |
Title: |
Osteopontin Deficiency Alters Biliary Homeostasis and Protects against Gallstone Formation. |
Volume: |
6 |
|
Pages: |
30215 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nuñez-Garcia M |
Year: |
2017 |
Journal: |
J Lipid Res |
Title: |
Osteopontin regulates the cross-talk between phosphatidylcholine and cholesterol metabolism in mouse liver. |
Volume: |
58 |
Issue: |
9 |
Pages: |
1903-1915 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ma K |
Year: |
2009 |
Journal: |
PLoS One |
Title: |
Circadian dysregulation disrupts bile acid homeostasis. |
Volume: |
4 |
Issue: |
8 |
Pages: |
e6843 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gadaleta RM |
Year: |
2018 |
Journal: |
Sci Rep |
Title: |
Suppression of Hepatic Bile Acid Synthesis by a non-tumorigenic FGF19 analogue Protects Mice from Fibrosis and Hepatocarcinogenesis. |
Volume: |
8 |
Issue: |
1 |
Pages: |
17210 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen AMK |
Year: |
2018 |
Journal: |
Biochem J |
Title: |
Differential receptor selectivity of the FGF15/FGF19 orthologues determines distinct metabolic activities in db/db mice. |
Volume: |
475 |
Issue: |
18 |
Pages: |
2985-2996 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schmidt DR |
Year: |
2010 |
Journal: |
J Biol Chem |
Title: |
Regulation of bile acid synthesis by fat-soluble vitamins A and D. |
Volume: |
285 |
Issue: |
19 |
Pages: |
14486-94 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kong B |
Year: |
2019 |
Journal: |
Dig Liver Dis |
Title: |
FXR deficiency alters bile acid pool composition and exacerbates chronic alcohol induced liver injury. |
Volume: |
51 |
Issue: |
4 |
Pages: |
570-576 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miyata M |
Year: |
2009 |
Journal: |
Drug Metab Dispos |
Title: |
Cholesterol feeding prevents hepatic accumulation of bile acids in cholic acid-fed farnesoid X receptor (FXR)-null mice: FXR-independent suppression of intestinal bile acid absorption. |
Volume: |
37 |
Issue: |
2 |
Pages: |
338-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li Q |
Year: |
2007 |
Journal: |
Mol Cell Biol |
Title: |
Tissue- and nuclear receptor-specific function of the C-terminal LXXLL motif of coactivator NCoA6/AIB3 in mice. |
Volume: |
27 |
Issue: |
23 |
Pages: |
8073-86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chartoumpekis DV |
Year: |
2013 |
Journal: |
Oxid Med Cell Longev |
Title: |
Hepatic gene expression profiling in Nrf2 knockout mice after long-term high-fat diet-induced obesity. |
Volume: |
2013 |
|
Pages: |
340731 |
|
•
•
•
•
•
|
Publication |
First Author: |
Weerachayaphorn J |
Year: |
2012 |
Journal: |
Am J Physiol Gastrointest Liver Physiol |
Title: |
Nuclear factor-E2-related factor 2 is a major determinant of bile acid homeostasis in the liver and intestine. |
Volume: |
302 |
Issue: |
9 |
Pages: |
G925-36 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ballatori N |
Year: |
2008 |
Journal: |
Am J Physiol Gastrointest Liver Physiol |
Title: |
Ostalpha-Ostbeta is required for bile acid and conjugated steroid disposition in the intestine, kidney, and liver. |
Volume: |
295 |
Issue: |
1 |
Pages: |
G179-G186 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hashimoto K |
Year: |
2006 |
Journal: |
J Biol Chem |
Title: |
Cross-talk between thyroid hormone receptor and liver X receptor regulatory pathways is revealed in a thyroid hormone resistance mouse model. |
Volume: |
281 |
Issue: |
1 |
Pages: |
295-302 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chanda D |
Year: |
2010 |
Journal: |
Nucleic Acids Res |
Title: |
Transcriptional corepressor SHP recruits SIRT1 histone deacetylase to inhibit LRH-1 transactivation. |
Volume: |
38 |
Issue: |
14 |
Pages: |
4607-19 |
|
•
•
•
•
•
|
Publication |
First Author: |
Drover VA |
Year: |
2004 |
Journal: |
Endocrinology |
Title: |
Regulation of the human cholesterol 7alpha-hydroxylase gene (CYP7A1) by thyroid hormone in transgenic mice. |
Volume: |
145 |
Issue: |
2 |
Pages: |
574-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Han S |
Year: |
2010 |
Journal: |
Mol Endocrinol |
Title: |
A novel bile acid-activated vitamin D receptor signaling in human hepatocytes. |
Volume: |
24 |
Issue: |
6 |
Pages: |
1151-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Buler M |
Year: |
2011 |
Journal: |
Biochem Pharmacol |
Title: |
Energy sensing factors PGC-1α and SIRT1 modulate PXR expression and function. |
Volume: |
82 |
Issue: |
12 |
Pages: |
2008-15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Henkel AS |
Year: |
2013 |
Journal: |
Am J Physiol Gastrointest Liver Physiol |
Title: |
Hepatic overexpression of Abcb11 in mice promotes the conservation of bile acids within the enterohepatic circulation. |
Volume: |
304 |
Issue: |
2 |
Pages: |
G221-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Luo J |
Year: |
2014 |
Journal: |
Sci Transl Med |
Title: |
A nontumorigenic variant of FGF19 treats cholestatic liver diseases. |
Volume: |
6 |
Issue: |
247 |
Pages: |
247ra100 |
|
•
•
•
•
•
|
Publication |
First Author: |
Elias I |
Year: |
2016 |
Journal: |
Diabetes |
Title: |
ALOX5AP Overexpression in Adipose Tissue Leads to LXA4 Production and Protection Against Diet-Induced Obesity and Insulin Resistance. |
Volume: |
65 |
Issue: |
8 |
Pages: |
2139-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Athanason MG |
Year: |
2016 |
Journal: |
Mol Cell Endocrinol |
Title: |
Quantitative proteomic profiling reveals hepatic lipogenesis and liver X receptor activation in the PANDER transgenic model. |
Volume: |
436 |
|
Pages: |
41-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang C |
Year: |
2014 |
Journal: |
Curr Mol Med |
Title: |
Hepatocyte FRS2α is essential for the endocrine fibroblast growth factor to limit the amplitude of bile acid production induced by prandial activity. |
Volume: |
14 |
Issue: |
6 |
Pages: |
703-711 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shaw RPH |
Year: |
2022 |
Journal: |
Endocrinology |
Title: |
Loss of Hepatic Small Heterodimer Partner Elevates Ileal Bile Acids and Alters Cell Cycle-related Genes in Male Mice. |
Volume: |
163 |
Issue: |
6 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bhat N |
Year: |
2022 |
Journal: |
FASEB J |
Title: |
TCF7L2 transcriptionally regulates Fgf15 to maintain bile acid and lipid homeostasis through gut-liver crosstalk. |
Volume: |
36 |
Issue: |
3 |
Pages: |
e22185 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ellis EC |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
Mice with chimeric livers are an improved model for human lipoprotein metabolism. |
Volume: |
8 |
Issue: |
11 |
Pages: |
e78550 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yamamoto Y |
Year: |
2006 |
Journal: |
J Biol Chem |
Title: |
Estrogen receptor alpha mediates 17alpha-ethynylestradiol causing hepatotoxicity. |
Volume: |
281 |
Issue: |
24 |
Pages: |
16625-31 |
|
•
•
•
•
•
|
Publication |
First Author: |
Slijepcevic D |
Year: |
2017 |
Journal: |
Hepatology |
Title: |
Hepatic uptake of conjugated bile acids is mediated by both sodium taurocholate cotransporting polypeptide and organic anion transporting polypeptides and modulated by intestinal sensing of plasma bile acid levels in mice. |
Volume: |
66 |
Issue: |
5 |
Pages: |
1631-1643 |
|
•
•
•
•
•
|
Publication |
First Author: |
Quinet EM |
Year: |
2006 |
Journal: |
Mol Pharmacol |
Title: |
Liver X receptor (LXR)-beta regulation in LXRalpha-deficient mice: implications for therapeutic targeting. |
Volume: |
70 |
Issue: |
4 |
Pages: |
1340-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Matasconi M |
Year: |
2005 |
Journal: |
Biochim Biophys Acta |
Title: |
Pituitary control of cholesterol metabolism in normal and LDL receptor knock-out mice: effects of hypophysectomy and growth hormone treatment. |
Volume: |
1736 |
Issue: |
3 |
Pages: |
221-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Weber AA |
Year: |
2021 |
Journal: |
Drug Metab Dispos |
Title: |
Regulation of Intestinal UDP-Glucuronosyltransferase 1A1 by the Farnesoid X Receptor Agonist Obeticholic Acid Is Controlled by Constitutive Androstane Receptor through Intestinal Maturation. |
Volume: |
49 |
Issue: |
1 |
Pages: |
12-19 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yu C |
Year: |
2005 |
Journal: |
J Biol Chem |
Title: |
Independent repression of bile acid synthesis and activation of c-Jun N-terminal kinase (JNK) by activated hepatocyte fibroblast growth factor receptor 4 (FGFR4) and bile acids. |
Volume: |
280 |
Issue: |
18 |
Pages: |
17707-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stroeve JH |
Year: |
2010 |
Journal: |
Lab Invest |
Title: |
Intestinal FXR-mediated FGF15 production contributes to diurnal control of hepatic bile acid synthesis in mice. |
Volume: |
90 |
Issue: |
10 |
Pages: |
1457-67 |
|
•
•
•
•
•
|
Publication |
First Author: |
Trenteseaux C |
Year: |
2017 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Perinatal Hypercholesterolemia Exacerbates Atherosclerosis Lesions in Offspring by Altering Metabolism of Trimethylamine-N-Oxide and Bile Acids. |
Volume: |
37 |
Issue: |
11 |
Pages: |
2053-2063 |
|
•
•
•
•
•
|
Publication |
First Author: |
Park YJ |
Year: |
2008 |
Journal: |
Hepatology |
Title: |
Loss of orphan receptor small heterodimer partner sensitizes mice to liver injury from obstructive cholestasis. |
Volume: |
47 |
Issue: |
5 |
Pages: |
1578-86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zollner G |
Year: |
2006 |
Journal: |
Am J Physiol Gastrointest Liver Physiol |
Title: |
Coordinated induction of bile acid detoxification and alternative elimination in mice: role of FXR-regulated organic solute transporter-alpha/beta in the adaptive response to bile acids. |
Volume: |
290 |
Issue: |
5 |
Pages: |
G923-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang Y |
Year: |
2017 |
Journal: |
Toxicol Sci |
Title: |
Editor's Highlight: Clofibrate Decreases Bile Acids in Livers of Male Mice by Increasing Biliary Bile Acid Excretion in a PPARα-Dependent Manner. |
Volume: |
160 |
Issue: |
2 |
Pages: |
351-360 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lukovac S |
Year: |
2009 |
Journal: |
Am J Physiol Gastrointest Liver Physiol |
Title: |
Effects of essential fatty acid deficiency on enterohepatic circulation of bile salts in mice. |
Volume: |
297 |
Issue: |
3 |
Pages: |
G520-31 |
|
•
•
•
•
•
|
Publication |
First Author: |
Christensen KE |
Year: |
2015 |
Journal: |
Am J Clin Nutr |
Title: |
High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice. |
Volume: |
101 |
Issue: |
3 |
Pages: |
646-58 |
|
•
•
•
•
•
|
Publication |
First Author: |
Song Y |
Year: |
2015 |
Journal: |
J Hepatol |
Title: |
Thyroid-stimulating hormone regulates hepatic bile acid homeostasis via SREBP-2/HNF-4α/CYP7A1 axis. |
Volume: |
62 |
Issue: |
5 |
Pages: |
1171-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fang S |
Year: |
2007 |
Journal: |
Mol Cell Biol |
Title: |
Coordinated recruitment of histone methyltransferase G9a and other chromatin-modifying enzymes in SHP-mediated regulation of hepatic bile acid metabolism. |
Volume: |
27 |
Issue: |
4 |
Pages: |
1407-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nguyen JT |
Year: |
2021 |
Journal: |
Endocrinology |
Title: |
Deletion of Intestinal SHP Impairs Short-term Response to Cholic Acid Challenge in Male Mice. |
Volume: |
162 |
Issue: |
8 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Dong Z |
Year: |
2022 |
Journal: |
Cell Mol Gastroenterol Hepatol |
Title: |
Hepatic Reduction in Cholesterol 25-Hydroxylase Aggravates Diet-induced Steatosis. |
Volume: |
13 |
Issue: |
4 |
Pages: |
1161-1179 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
470
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
500
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
507
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
501
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
509
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
470
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
507
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
507
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
500
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
503
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
503
|
Fragment?: |
false |
|
•
•
•
•
•
|