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Search results 101 to 200 out of 201 for Chd1

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Categories

Hits by Strain

Hits by Category

Type Details Score
Gene
530096 | CHCT1
Type: gene
Organism: cattle
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Gene
100855583 | CHCT1
Type: gene
Organism: dog, domestic
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Gene
716713 | CHCT1
Type: gene
Organism: macaque, rhesus
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HT Experiment
GSE62796 | Chd1 is essential in the endothelial lineage for the emergence of definitive hematopoietic stem/progenitor cells
Series Id: E-GEOD-62796
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
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Protein
P40201
Organism: Mus musculus/domesticus
Length: 1711  
Fragment?: false
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Publication
21623345 | -
First Author: Ryan DP
Year: 2011
Journal: EMBO J
Title: The DNA-binding domain of the Chd1 chromatin-remodelling enzyme contains SANT and SLIDE domains.
Volume: 30
Issue: 13
Pages: 2596-609
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Publication
27591891 | -
First Author: Mohanty B
Year: 2016
Journal: J Mol Biol
Title: The Chromatin Remodelling Protein CHD1 Contains a Previously Unrecognised C-Terminal Helical Domain.
Volume: 428
Issue: 21
Pages: 4298-4314
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Protein Coding Gene
MGP_CAROLIEiJ_G0016904 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0018879 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0018846 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0018816 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0018819 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0018633 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1920884 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0019271 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0018188 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0018604 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0018712 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0018701 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0018782 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0018728 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0019311 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0017957 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0018239 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0018034 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0017749 | -
Type: protein_coding_gene
Organism: Mus spretus
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Allele
Chct1<+> | MGI:5479725
 
Name: CHD1 helical C-terminal domain containing 1; wild type
Allele Type: Not Specified
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Absent
Sex: Male
Emaps: EMAPS:1868128
Stage: TS28
Assay Id: MGI:6692055
Age: postnatal adult
Image: BCM_1059259
Note: vas deferens
Specimen Label: BCM_1059259
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692055
Age: postnatal adult
Image: BCM_1059259
Specimen Label: BCM_1059259
Detected: true
Specimen Num: 1
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Publication
33846633 | -
First Author: Farnung L
Year: 2021
Journal: Nat Struct Mol Biol
Title: Structural basis of nucleosome transcription mediated by Chd1 and FACT.
Volume: 28
Issue: 4
Pages: 382-387
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Interaction Experiment
Kelley DE (1999)
Description: CHD1 interacts with SSRP1 and depends on both its chromodomain and its ATPase/helicase-like domain for proper association with chromatin.
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Allele
Chct1<Gt(OST282958)Lex> | MGI:4263517
 
Name: CHD1 helical C-terminal domain containing 1; gene trap OST282958, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Chct1<Gt(OST401389)Lex> | MGI:4305852
 
Name: CHD1 helical C-terminal domain containing 1; gene trap OST401389, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Chct1<tm1e(EUCOMM)Wtsi> | MGI:4441765
Name: CHD1 helical C-terminal domain containing 1; targeted mutation 1e, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Chct1<Gt(OST76536)Lex> | MGI:4174890
 
Name: CHD1 helical C-terminal domain containing 1; gene trap OST76536, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Chct1<Gt(OST267089)Lex> | MGI:4257341
 
Name: CHD1 helical C-terminal domain containing 1; gene trap OST267089, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Chct1<Gt(OST417868)Lex> | MGI:4310634
 
Name: CHD1 helical C-terminal domain containing 1; gene trap OST417868, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Chct1<Gt(OST354628)Lex> | MGI:4291725
 
Name: CHD1 helical C-terminal domain containing 1; gene trap OST354628, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Chct1<Gt(OST31220)Lex> | MGI:4151184
 
Name: CHD1 helical C-terminal domain containing 1; gene trap OST31220, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Chct1<tm1a(EUCOMM)Wtsi> | MGI:4441950
Name: CHD1 helical C-terminal domain containing 1; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Chct1<Gt(OST262342)Lex> | MGI:4255885
 
Name: CHD1 helical C-terminal domain containing 1; gene trap OST262342, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Chct1<Gt(OST116225)Lex> | MGI:4190311
 
Name: CHD1 helical C-terminal domain containing 1; gene trap OST116225, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Chct1<Gt(OST234410)Lex> | MGI:4243963
 
Name: CHD1 helical C-terminal domain containing 1; gene trap OST234410, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Chct1<Gt(OST252428)Lex> | MGI:4252065
 
Name: CHD1 helical C-terminal domain containing 1; gene trap OST252428, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Chct1<Gt(OST458504)Lex> | MGI:4324456
 
Name: CHD1 helical C-terminal domain containing 1; gene trap OST458504, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Chct1<Gt(OST150129)Lex> | MGI:4206369
 
Name: CHD1 helical C-terminal domain containing 1; gene trap OST150129, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Chct1<Gt(OST210018)Lex> | MGI:4233621
 
Name: CHD1 helical C-terminal domain containing 1; gene trap OST210018, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Chct1<Gt(OST24738)Lex> | MGI:4146835
 
Name: CHD1 helical C-terminal domain containing 1; gene trap OST24738, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Chct1<Gt(OST80892)Lex> | MGI:4176713
 
Name: CHD1 helical C-terminal domain containing 1; gene trap OST80892, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Chct1<Gt(OST258284)Lex> | MGI:4254147
 
Name: CHD1 helical C-terminal domain containing 1; gene trap OST258284, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Chct1<Gt(OST396354)Lex> | MGI:4304976
 
Name: CHD1 helical C-terminal domain containing 1; gene trap OST396354, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Chct1<Gt(OST133001)Lex> | MGI:4198609
 
Name: CHD1 helical C-terminal domain containing 1; gene trap OST133001, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Chct1<Gt(OST206675)Lex> | MGI:4231916
 
Name: CHD1 helical C-terminal domain containing 1; gene trap OST206675, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Chct1<Gt(OST125132)Lex> | MGI:4194716
 
Name: CHD1 helical C-terminal domain containing 1; gene trap OST125132, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Chct1<Gt(OST150117)Lex> | MGI:4206365
 
Name: CHD1 helical C-terminal domain containing 1; gene trap OST150117, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Chct1<Gt(OST259661)Lex> | MGI:4254599
 
Name: CHD1 helical C-terminal domain containing 1; gene trap OST259661, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Chct1<Gt(OST278783)Lex> | MGI:4261469
 
Name: CHD1 helical C-terminal domain containing 1; gene trap OST278783, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Chct1<tm1b(EUCOMM)Wtsi> | MGI:5548635
Name: CHD1 helical C-terminal domain containing 1; targeted mutation 1b, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Chct1<Gt(OST216841)Lex> | MGI:4236746
 
Name: CHD1 helical C-terminal domain containing 1; gene trap OST216841, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Chct1<Gt(OST10231)Lex> | MGI:4137576
 
Name: CHD1 helical C-terminal domain containing 1; gene trap OST10231, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Chct1<Gt(OST354548)Lex> | MGI:4291692
 
Name: CHD1 helical C-terminal domain containing 1; gene trap OST354548, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Chct1<Gt(OST2869)Lex> | MGI:4132958
 
Name: CHD1 helical C-terminal domain containing 1; gene trap OST2869, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Chct1<Gt(OST235060)Lex> | MGI:4244239
 
Name: CHD1 helical C-terminal domain containing 1; gene trap OST235060, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Chct1<Gt(OST429468)Lex> | MGI:4314154
 
Name: CHD1 helical C-terminal domain containing 1; gene trap OST429468, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Chct1<Gt(115C1)Cmhd> | MGI:4972202
 
Name: CHD1 helical C-terminal domain containing 1; gene trap 115C1, Centre for Modeling Human Disease
Allele Type: Gene trapped
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Allele
Chct1<Gt(OST182490)Lex> | MGI:4219012
 
Name: CHD1 helical C-terminal domain containing 1; gene trap OST182490, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Chct1<Gt(OST395729)Lex> | MGI:4304932
 
Name: CHD1 helical C-terminal domain containing 1; gene trap OST395729, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Chct1<Gt(OST417870)Lex> | MGI:4310635
 
Name: CHD1 helical C-terminal domain containing 1; gene trap OST417870, Lexicon Genetics
Allele Type: Gene trapped
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Publication
12890497 | -
First Author: Tai HH
Year: 2003
Journal: Biochem Biophys Res Commun
Title: CHD1 associates with NCoR and histone deacetylase as well as with RNA splicing proteins.
Volume: 308
Issue: 1
Pages: 170-6
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Publication
15647753 | -
First Author: Pray-Grant MG
Year: 2005
Journal: Nature
Title: Chd1 chromodomain links histone H3 methylation with SAGA- and SLIK-dependent acetylation.
Volume: 433
Issue: 7024
Pages: 434-8
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Publication
10199952 | -
First Author: Kelley DE
Year: 1999
Journal: Chromosoma
Title: CHD1 interacts with SSRP1 and depends on both its chromodomain and its ATPase/helicase-like domain for proper association with chromatin.
Volume: 108
Issue: 1
Pages: 10-25
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Strain
MGI:6142932 | C57BL/6N-A<tm1Brd>/a Chct1<tm1a(EUCOMM)Wtsi>/BayMmucd
Attribute String: mutant strain, coisogenic, targeted mutation
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Allele
Chct1<Gt(IST14905C10)Tigm> | MGI:5265457
 
Name: CHD1 helical C-terminal domain containing 1; gene trap IST14905C10, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Strain
MGI:5887247 | C57BL/6N-Chct1<tm1b(EUCOMM)Wtsi>/Bay
Attribute String: coisogenic, targeted mutation
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Genotype
Genotype
Symbol: Chct1/Chct1
Background: involves: 129 * BALB/c * C57BL/6N
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Chct1/Chct1
Background: C57BL/6N-Chct1/Bay
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Chct1/Chct1<+>
Background: C57BL/6N-Chct1/Bay
Zygosity: ht
Has Mutant Allele: true
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Protein
G3UWS6
Organism: Mus musculus/domesticus
Length: 164  
Fragment?: true
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Publication
24853335 | -
 
First Author: Qin S
Year: 2014
Journal: Nat Commun
Title: Structural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1.
Volume: 5
Pages: 3952
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Protein Domain
IPR040793 | CDH1_2_SANT_HL1
Type: Domain
Description: CDH1 is an ATP-dependent chromatin-remodelling factor and plays an important role in regulating nucleosome assembly and mobilization. CHD1 consists of double chromodomain, SNF2-related ATPase domain, and a C-terminal DNA-binding domain. The DNA-binding domain contains SANT (Swi3, Ada2, N-CoR, TFIIIB) and SLIDE (SANT-like ISWI) domains in its C-terminal region []. SANT domains are structurally related to Myb-like domains are common motifs found in chromatin interacting proteins. Deletion of individual SANT or SLIDE domains in CDH1 does not significantly affect nucleosome binding, but combined deletion of both domains severely compromise binding, suggesting that the SANT-SLIDE motif recognizes DNA/nucleosomes as a single cooperative unit. SANT sequences of Chd1 proteins are the most distantly relation group of sequences relation to other SANT/Myb sequences, and are more diverse than other SANT proteins []. The SANT and SLIDE regions are well conserved in both Chd1 and ISWI (imitation switch) remodelling enzymes []. This domain comprises the SANT region and the helical linker region 1 (HL1).
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Publication
12127990 | -
First Author: Jae Yoo E
Year: 2002
Journal: Biochem Biophys Res Commun
Title: Hrp3, a chromodomain helicase/ATPase DNA binding protein, is required for heterochromatin silencing in fission yeast.
Volume: 295
Issue: 4
Pages: 970-4
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Protein Domain
IPR041150 | Cdh1_DBD
Type: Domain
Description: This domain can be found in chromodomain helicase DNA-binding protein 1 (Chd1) present in Saccharomyces cerevisiae. Cdh1 proteins have been associated with the efficient assembly and spacing of nucleosomes []. Chd1 consists of a double chromodomain, an Snf2-related ATPase domain and a C-terminal DNA binding domain [, ].This domain comprises the first four helices of the Chd1 DNA binding domain, which can be divided into regions SANT, HL1 and the β-linker. The HL1 region comprises of some 40 residues specific to budding yeast that are unlikely to form such a prominent feature or perform a conserved function in other species. Basic residues on the alpha-1 helix are thought to be important for DNA interaction [].This domain is also found in the Hrp3 protein, another member of the Cdh1 family in Schizosaccharomyces pombe. Like Cdh1, Hrp3 also comprises two chromo-domains, SNF2-like ATPase/7 helicase domains, and a C-terminal DNA binding domain [].
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Protein Domain
IPR045695 | TMEM131-like_conserved
Type: Domain
Description: Transmembrane protein 131-like (TMEM131L) was identified as a negative regulator of thymocyte proliferation that acts through mixed Wnt-dependent and independent mechanisms. It has two isoforms, L and S, which have different subcellular localisation. L isoform, the membrane-associated form, inhibits canonical Wnt/beta-catenin signalling through the induction of lysosome-dependent degradation of the active phosphorylated form of the LRP6 coreceptor. This protein contains three conserved homology domains (CHD1, 2 and 3), a transmembrane region and a C-terminal serine-rich region []. This entry represents a conserved domain found in TMEM131 and TMEM131L. This domain is C-terminal to the CHD1 domain.
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Protein
A0A0G2JEZ3
Organism: Mus musculus/domesticus
Length: 220  
Fragment?: true
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Protein
A0A087WQG5
Organism: Mus musculus/domesticus
Length: 171  
Fragment?: true
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Protein
A0A087WRG7
Organism: Mus musculus/domesticus
Length: 146  
Fragment?: true
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Publication
23690469 | -
First Author: Maharzi N
Year: 2013
Journal: J Immunol
Title: Identification of TMEM131L as a novel regulator of thymocyte proliferation in humans.
Volume: 190
Issue: 12
Pages: 6187-97
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Publication
27357688 | J:234235
First Author: Miyata H
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice.
Volume: 113
Issue: 28
Pages: 7704-10
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Protein
Q3U3D7
Organism: Mus musculus/domesticus
Length: 1597  
Fragment?: false
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Protein
O70472
Organism: Mus musculus/domesticus
Length: 1877  
Fragment?: false
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Protein
Q8C771
Organism: Mus musculus/domesticus
Length: 774  
Fragment?: true
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Protein
A0A0B4J1F5
Organism: Mus musculus/domesticus
Length: 1535  
Fragment?: false
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Protein
E9PZM4
Organism: Mus musculus/domesticus
Length: 1827  
Fragment?: false
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:73796
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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