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Search results 401 to 500 out of 510 for Grn

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Type Details Score
Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein Coding Gene
MGI:2675494 | Gzmn
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
- | J:84594
   
First Author: Matsui H
Year: 2003
Journal: GenBank Submission
Title: Mus musculus GrN mRNA for granzyme N, complete cds
Pages: AB049454
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HT Experiment
GSE78747 | GRN knockout, sorted brain cells
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
33323378 | J:303989
First Author: Dong D
Year: 2021
Journal: Cancer Res
Title: A GRN Autocrine-Dependent FAM135B/AKT/mTOR Feedforward Loop Promotes Esophageal Squamous Cell Carcinoma Progression.
Volume: 81
Issue: 4
Pages: 910-922
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Allele
Grn<em1Smoc> | MGI:7290027
Name: granulin; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Gt(ROSA)26Sor<tm1(GRN)Pvd> | MGI:5636723
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Philip Van Damme
Allele Type: Targeted
Attribute String: Conditional ready, Humanized sequence, Inserted expressed sequence
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HT Experiment
E-GEOD-31840 | Gene Expression Study in Progranulin-Deficient Mice
Series Id: GSE31840
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Allele
Grn<tm1.1Far> | MGI:4949110
Name: granulin; targeted mutation 1.1, Bob Farese
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Grn<tm2.1Far> | MGI:5811645
Name: granulin; targeted mutation 2.1, Bob Farese
Allele Type: Targeted
Attribute String: Humanized sequence
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Allele
Grn<tm1.1Hiok> | MGI:6150889
Name: granulin; targeted mutation 1.1, Hitoshi Okazawa
Allele Type: Targeted
Attribute String: Humanized sequence
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Allele
Tg(Camk2a-Tardbp)#Ckjs | MGI:4830510
Name: transgene insertion, C K James Shen
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Grn)33Mrl | MGI:6434338
Name: transgene insert 33, Merck Research Laboratory
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Grn)26Mrl | MGI:6434340
Name: transgene insertion 26, Merck Research Laboratory
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Grn)42Mrl | MGI:6434335
Name: transgene insert 42, Merck Research Laboratory
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Hprt1<tm1(GRN)Blrl> | MGI:6512847
Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 1, Blair R Leavitt
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(Prnp-TARDBP)3cPtrc | MGI:5002476
Name: transgene insertion 3c, Leonard Petrucelli
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(TARDBP*A315T)#Jpj | MGI:5476824
Name: transgene insertion, Jean-Pierre Julien
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Transgene
MGI:4830518 | Tg(Camk2a-Tardbp)#Ckjs
Type: transgene
Organism: mouse, laboratory
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Allele
Tg(Thy1-TARDBP*)BOddo | MGI:5310969
Name: transgene insertion B, Salvatore Oddo
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Genotype
Genotype
Symbol: Tg(Camk2a-Tardbp)#Ckjs/Tg(Camk2a-Tardbp)#Ckjs
Background: FVB/N-Tg(Camk2a-Tardbp)#Ckjs
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Thy1-TARDBP*)BOddo/?
Background: C57BL/6-Tg(Thy1-TARDBP*)BOddo
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Grn/Grn
Background: involves: 129S4/SvJae * C57BL/6J * FVB/N
Zygosity: hm
Has Mutant Allele: true
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DO Term
DOID:0060672 | Grn-related frontotemporal lobar degeneration with Tdp43 inclusions
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Genotype
Genotype
Symbol: Grn/Grn<+>
Background: involves: C57BL/6J
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Grn/Grn
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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DO Term
DOID:0110732 | neuronal ceroid lipofuscinosis 11
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HT Experiment
GSE181135 | Loss of TREM2 reduces hyperactivation of progranulin deficient microglia but not lysosomal pathology
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE185510 | Loss of TREM2 reduces hyperactivation of progranulin deficient microglia but not lysosomal pathology [14 months]
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
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Strain
MGI:6438381 | C57BL/6-Tg(Grn)33Mrl/Tac
Attribute String: mutant strain, coisogenic, transgenic
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Allele
Grn<tm1Blrl> | MGI:4867226
Name: granulin; targeted mutation 1, Blair R Leavitt
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Strain
MGI:6438394 | C57BL/6-Tg(Grn)26Mrl/Tac
Attribute String: mutant strain, coisogenic, transgenic
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Strain
MGI:6438380 | C57BL/6-Tg(Grn)42Mrl/Tac
Attribute String: mutant strain, coisogenic, transgenic
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Transgene
MGI:5002478 | Tg(Prnp-TARDBP)3cPtrc
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5476817 | Tg(TARDBP*A315T)#Jpj
Type: transgene
Organism: mouse, laboratory
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Allele
Tg(TARDBP*G348C)#Jpj | MGI:5476825
Name: transgene insertion, Jean-Pierre Julien
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Transgene
MGI:5476818 | Tg(TARDBP*G348C)#Jpj
Type: transgene
Organism: mouse, laboratory
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Allele
Tg(TARDBP)#Jpj | MGI:5476821
Name: transgene insertion, Jean-Pierre Julien
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Transgene
MGI:5476814 | Tg(TARDBP)#Jpj
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5310798 | Tg(Thy1-TARDBP*)BOddo
Type: transgene
Organism: mouse, laboratory
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Genotype
Genotype
Symbol: Tg(Prnp-TARDBP)3cPtrc/Tg(Prnp-TARDBP)3cPtrc
Background: C57BL/6-Tg(Prnp-TARDBP)3cPtrc
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(TARDBP*A315T)#Jpj/?
Background: involves: C3H * C57BL/6
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(TARDBP*G348C)#Jpj/?
Background: involves: C3H * C57BL/6
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(TARDBP)#Jpj/?
Background: involves: C3H * C57BL/6
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Thy1-TARDBP*)BOddo/Tg(Thy1-TARDBP*)BOddo
Background: C57BL/6-Tg(Thy1-TARDBP*)BOddo
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Grn/Grn
Background: involves: C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Grn/Grn
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Grn/Grn<+>
Background: Not Specified
Zygosity: ht
Has Mutant Allele: true
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Protein Coding Gene
MGI:2387629 | Tardbp
Type: protein_coding_gene
Organism: mouse, laboratory
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HT Experiment
GSE197858 | A spatio-temporally constrained gene regulatory network directed by PBX1/2 acquires limb patterning specificity via HAND2 [single-cell RNA-seq]
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Strain
MGI:6512846 | B6.Cg-Grn<tm1.2Blrl> Hprt1<tm1(GRN)Blrl>/J
Attribute String: congenic, mutant strain, targeted mutation
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Publication
20953163 | J:167182
First Author: Muto A
Year: 2010
Journal: EMBO J
Title: Bach2 represses plasma cell gene regulatory network in B cells to promote antibody class switch.
Volume: 29
Issue: 23
Pages: 4048-61
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Publication
21613984 | J:203903
 
First Author: Sciammas R
Year: 2011
Journal: Mol Syst Biol
Title: An incoherent regulatory network architecture that orchestrates B cell diversification in response to antigen signaling.
Volume: 7
Pages: 495
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Publication
36747024 | J:333044
First Author: De Schepper S
Year: 2023
Journal: Nat Neurosci
Title: Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer's disease.
Volume: 26
Issue: 3
Pages: 406-415
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Publication
33321106 | J:302547
First Author: Kathiriya IS
Year: 2021
Journal: Dev Cell
Title: Modeling Human TBX5 Haploinsufficiency Predicts Regulatory Networks for Congenital Heart Disease.
Volume: 56
Issue: 3
Pages: 292-309.e9
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Publication
28273455 | J:250762
First Author: Itoh-Nakadai A
Year: 2017
Journal: Cell Rep
Title: A Bach2-Cebp Gene Regulatory Network for the Commitment of Multipotent Hematopoietic Progenitors.
Volume: 18
Issue: 10
Pages: 2401-2414
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Publication
25155555 | J:214806
First Author: Wang S
Year: 2014
Journal: Dev Cell
Title: A gene regulatory network controls the binary fate decision of rod and bipolar cells in the vertebrate retina.
Volume: 30
Issue: 5
Pages: 513-27
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Publication
27532212 | J:236376
First Author: Zheng D
Year: 2016
Journal: Genesis
Title: Pou4f2-GFP knock-in mouse line: A model for studying retinal ganglion cell development.
Volume: 54
Issue: 10
Pages: 534-541
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Publication
35649376 | J:326086
First Author: Sinha T
Year: 2022
Journal: Cell Rep
Title: Differential Etv2 threshold requirement for endothelial and erythropoietic development.
Volume: 39
Issue: 9
Pages: 110881
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Publication
30510257 | J:271490
First Author: Swarup V
Year: 2019
Journal: Nat Med
Title: Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia.
Volume: 25
Issue: 1
Pages: 152-164
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Publication
27880916 | J:241605
First Author: Kim JW
Year: 2016
Journal: Cell Rep
Title: NRL-Regulated Transcriptome Dynamics of Developing Rod Photoreceptors.
Volume: 17
Issue: 9
Pages: 2460-2473
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Publication
34433069 | J:316926
First Author: Wu Y
Year: 2021
Journal: Cell Rep
Title: Microglial lysosome dysfunction contributes to white matter pathology and TDP-43 proteinopathy in GRN-associated FTD.
Volume: 36
Issue: 8
Pages: 109581
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Publication
35075189 | J:320197
First Author: Magaletta ME
Year: 2022
Journal: Nat Commun
Title: Integration of single-cell transcriptomes and chromatin landscapes reveals regulatory programs driving pharyngeal organ development.
Volume: 13
Issue: 1
Pages: 457
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HT Experiment
GSE236256 | Enhancer grammar of liver cell types and hepatocyte zonation states [multiome_validation]
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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HT Experiment
GSE218465 | Enhancer grammar of liver cell types and hepatocyte zonation states [scRNA-seq]
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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HT Experiment
GSE218468 | Enhancer grammar of liver cell types and hepatocyte zonation states [multiome]
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Strain
MGI:5638038 | B6J.Cg-Tg(Pgk1-cre)1Lni Gt(ROSA)26Sor<tm1(GRN)Pvd> Tg(SOD1*G93A)1Gur
Attribute String: congenic, mutant strain, targeted mutation, transgenic
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Pgk1-cre)1Lni/? Tg(SOD1*G93A)1Gur/?
Background: B6J.Cg-Tg(Pgk1-cre)1Lni Gt(ROSA)26Sor Tg(SOD1*G93A)1Gur
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor Tg(Pgk1-cre)1Lni/? Tg(SOD1*G93A)1Gur/?
Background: B6J.Cg-Tg(Pgk1-cre)1Lni Gt(ROSA)26Sor Tg(SOD1*G93A)1Gur
Zygosity: cn
Has Mutant Allele: true
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Publication
29659575 | J:262053
First Author: Tan Z
Year: 2018
Journal: PLoS Genet
Title: Synergistic co-regulation and competition by a SOX9-GLI-FOXA phasic transcriptional network coordinate chondrocyte differentiation transitions.
Volume: 14
Issue: 4
Pages: e1007346
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Publication
20651287 | J:175025
First Author: Lai D
Year: 2010
Journal: Circ Res
Title: Neuregulin 1 sustains the gene regulatory network in both trabecular and nontrabecular myocardium.
Volume: 107
Issue: 6
Pages: 715-27
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Publication
34861428 | J:316185
 
First Author: Cesario J
Year: 2021
Journal: Gene Expr Patterns
Title: Candidate positive targets of LHX6 and LHX8 transcription factors in the developing upper jaw.
Volume: 43
Pages: 119227
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Publication
21998302 | J:178731
First Author: Xie Q
Year: 2011
Journal: J Biol Chem
Title: The orchestration of mammalian tissue morphogenesis through a series of coherent feed-forward loops.
Volume: 286
Issue: 50
Pages: 43259-71
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Publication
38063857 | J:344235
 
First Author: Nguyen TT
Year: 2024
Journal: Development
Title: TFAP2 paralogs regulate midfacial development in part through a conserved ALX genetic pathway.
Volume: 151
Issue: 1
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Publication
18460603 | J:146349
First Author: Mu X
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Gene regulation logic in retinal ganglion cell development: Isl1 defines a critical branch distinct from but overlapping with Pou4f2.
Volume: 105
Issue: 19
Pages: 6942-7
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Publication
26358247 | J:288981
First Author: Clayton EL
Year: 2015
Journal: Acta Neuropathol
Title: Frontotemporal dementia caused by CHMP2B mutation is characterised by neuronal lysosomal storage pathology.
Volume: 130
Issue: 4
Pages: 511-23
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Publication
17962413 | J:127160
First Author: Pimanda JE
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development.
Volume: 104
Issue: 45
Pages: 17692-7
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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