Type |
Details |
Score |
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1832128 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691744 |
Age: |
postnatal adult |
Image: |
UC Davis_1858136 |
|
Specimen Label: |
UC Davis_1858136 |
Detected: |
true |
Specimen Num: |
21 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1832128 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691744 |
Age: |
postnatal adult |
Image: |
UC Davis_1858155 |
|
Specimen Label: |
UC Davis_1858155 |
Detected: |
true |
Specimen Num: |
39 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1832128 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691744 |
Age: |
postnatal adult |
Image: |
UC Davis_1858156 |
|
Specimen Label: |
UC Davis_1858156 |
Detected: |
true |
Specimen Num: |
40 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3599828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691744 |
Age: |
postnatal adult |
Image: |
UC Davis_1858151 |
|
Specimen Label: |
UC Davis_1858151 |
Detected: |
true |
Specimen Num: |
35 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3599828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691744 |
Age: |
postnatal adult |
Image: |
UC Davis_1858152 |
|
Specimen Label: |
UC Davis_1858152 |
Detected: |
true |
Specimen Num: |
36 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1885228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691744 |
Age: |
postnatal adult |
Image: |
UC Davis_1858121 |
|
Specimen Label: |
UC Davis_1858121 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3604860 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-11-17 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752524 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:3604896 |
Age: |
embryonic day 16.5 |
|
|
Specimen Label: |
Table 1 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1752528 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691744 |
Age: |
postnatal adult |
Image: |
UC Davis_1858177 |
|
Specimen Label: |
UC Davis_1858177 |
Detected: |
true |
Specimen Num: |
55 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1752528 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691744 |
Age: |
postnatal adult |
Image: |
UC Davis_1858130 |
|
Specimen Label: |
UC Davis_1858130 |
Detected: |
true |
Specimen Num: |
15 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1752528 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691744 |
Age: |
postnatal adult |
Image: |
UC Davis_1858131 |
|
Specimen Label: |
UC Davis_1858131 |
Detected: |
true |
Specimen Num: |
16 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1752528 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691744 |
Age: |
postnatal adult |
Image: |
UC Davis_1858153 |
|
Specimen Label: |
UC Davis_1858153 |
Detected: |
true |
Specimen Num: |
37 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1752528 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691744 |
Age: |
postnatal adult |
Image: |
UC Davis_1858154 |
|
Specimen Label: |
UC Davis_1858154 |
Detected: |
true |
Specimen Num: |
38 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3604860 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-11-17 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1702124 |
|
Stage: |
TS24 |
Assay Id: |
MGI:3604896 |
Age: |
embryonic day 16.5 |
|
|
Specimen Label: |
Table 1 |
Detected: |
false |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1702128 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691744 |
Age: |
postnatal adult |
Image: |
UC Davis_1858183 |
|
Specimen Label: |
UC Davis_1858183 |
Detected: |
true |
Specimen Num: |
60 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1702128 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691744 |
Age: |
postnatal adult |
Image: |
UC Davis_1858118 |
|
Specimen Label: |
UC Davis_1858118 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1702128 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691744 |
Age: |
postnatal adult |
Image: |
UC Davis_1858119 |
|
Specimen Label: |
UC Davis_1858119 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1702128 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691744 |
Age: |
postnatal adult |
Image: |
UC Davis_1858120 |
|
Specimen Label: |
UC Davis_1858120 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1702128 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691744 |
Age: |
postnatal adult |
Image: |
UC Davis_1858144 |
|
Specimen Label: |
UC Davis_1858144 |
Detected: |
true |
Specimen Num: |
28 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1702128 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691744 |
Age: |
postnatal adult |
Image: |
UC Davis_1858145 |
|
Specimen Label: |
UC Davis_1858145 |
Detected: |
true |
Specimen Num: |
29 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1929028 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691744 |
Age: |
postnatal adult |
Image: |
UC Davis_1858157 |
|
Specimen Label: |
UC Davis_1858157 |
Detected: |
true |
Specimen Num: |
41 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1929028 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691744 |
Age: |
postnatal adult |
Image: |
UC Davis_1858158 |
|
Specimen Label: |
UC Davis_1858158 |
Detected: |
true |
Specimen Num: |
42 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1915328 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691744 |
Age: |
postnatal adult |
Image: |
UC Davis_1858129 |
|
Specimen Label: |
UC Davis_1858129 |
Detected: |
true |
Specimen Num: |
14 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3604860 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-11-17 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3273024 |
|
Stage: |
TS24 |
Assay Id: |
MGI:3604896 |
Age: |
embryonic day 16.5 |
|
|
Specimen Label: |
Table 1 |
Detected: |
false |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1757728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691744 |
Age: |
postnatal adult |
Image: |
UC Davis_1858182 |
|
Specimen Label: |
UC Davis_1858182 |
Detected: |
true |
Specimen Num: |
59 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3281228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691744 |
Age: |
postnatal adult |
Image: |
UC Davis_1858192 |
|
Specimen Label: |
UC Davis_1858192 |
Detected: |
true |
Specimen Num: |
64 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:2991528 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691744 |
Age: |
postnatal adult |
Image: |
UC Davis_1858133 |
|
Specimen Label: |
UC Davis_1858133 |
Detected: |
true |
Specimen Num: |
18 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3604860 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-11-17 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689424 |
|
Stage: |
TS24 |
Assay Id: |
MGI:3604896 |
Age: |
embryonic day 16.5 |
|
|
Specimen Label: |
Table 1 |
Detected: |
false |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691744 |
Age: |
postnatal adult |
Image: |
UC Davis_1858172 |
|
Specimen Label: |
UC Davis_1858172 |
Detected: |
true |
Specimen Num: |
51 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1868228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691744 |
Age: |
postnatal adult |
Image: |
UC Davis_1858186 |
|
Specimen Label: |
UC Davis_1858186 |
Detected: |
true |
Specimen Num: |
63 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:1868228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6691744 |
Age: |
postnatal adult |
Image: |
UC Davis_1858159 |
|
Specimen Label: |
UC Davis_1858159 |
Detected: |
false |
Specimen Num: |
43 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:1868228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6691744 |
Age: |
postnatal adult |
Image: |
UC Davis_1858160 |
|
Specimen Label: |
UC Davis_1858160 |
Detected: |
false |
Specimen Num: |
44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tocchetti A |
Year: |
2003 |
Journal: |
Genomics |
Title: |
In silico analysis of the EPS8 gene family: genomic organization, expression profile, and protein structure. |
Volume: |
81 |
Issue: |
2 |
Pages: |
234-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Disanza A |
Year: |
2004 |
Journal: |
Nat Cell Biol |
Title: |
Eps8 controls actin-based motility by capping the barbed ends of actin filaments. |
Volume: |
6 |
Issue: |
12 |
Pages: |
1180-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jung H |
Year: |
2018 |
Journal: |
Nat Neurosci |
Title: |
Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice. |
Volume: |
21 |
Issue: |
9 |
Pages: |
1218-1228 |
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration |
Year: |
2001 |
|
Title: |
LocusLink Collaboration |
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|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Dickinson ME |
Year: |
2016 |
Journal: |
Nature |
Title: |
High-throughput discovery of novel developmental phenotypes. |
Volume: |
537 |
Issue: |
7621 |
Pages: |
508-514 |
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•
•
•
•
•
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Publication |
First Author: |
Haiming Tang, Dustin Ebert, Matthias Blum, Robert Finn, Paul Thomas |
Year: |
2023 |
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Title: |
TreeGrafter-generated GO annotations |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
FANTOM2 Data Curation in Mouse Genome Informatics |
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•
•
•
•
•
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Publication |
First Author: |
Koscielny G |
Year: |
2014 |
Journal: |
Nucleic Acids Res |
Title: |
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. |
Volume: |
42 |
Issue: |
Database issue |
Pages: |
D802-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
International Knockout Mouse Consortium |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of modified allele data from IKMC and creation of new knockout alleles |
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•
•
•
•
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Publication |
First Author: |
International Mouse Strain Resource |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of germline transmission data for alleles from IMSR strain data |
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•
•
•
•
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Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2009 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute |
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•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
Year: |
2014 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
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Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
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Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
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Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
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•
•
•
•
•
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Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
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•
•
•
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Publication |
First Author: |
Adams DJ |
Year: |
2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
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•
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Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
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•
•
•
•
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Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
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•
•
•
•
•
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Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
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Pages: |
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•
•
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•
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Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
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Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
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Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
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•
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Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
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Title: |
Annotation inferences using phylogenetic trees |
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•
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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•
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•
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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•
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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•
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•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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Publication |
First Author: |
Furness DN |
Year: |
2013 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Progressive hearing loss and gradual deterioration of sensory hair bundles in the ears of mice lacking the actin-binding protein Eps8L2. |
Volume: |
110 |
Issue: |
34 |
Pages: |
13898-903 |
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Protein Domain |
Type: |
Family |
Description: |
This entry includes EPS8 and EPS8L1-3 from animals.Epidermal growth factor receptor kinase substrate 8 (EPS8) is a signalling adapter that possesses actin binding, bundling, and barbed-end capping activities []. It forms a complex with Sos-1, Abi1 and the lipid kinase phosphoinositide 3-kinase (PI3-K) to regulate Rac activation that leads to actin cytoskeletal remodeling []. It is critical for dendritic cell migration []. It is involved in the initial growth of stereocilia in both inner hair cells and outer hair cells []. It also regulates axonal filopodia in hippocampal neurons in response to brain-derived neurotrophic factor (BDNF) []. It has been linked to proliferation, metastasis and prognosis of many malignant tumours [].Similarly to EPS8, EPSLs interact with Abi1 and Sos-1. However, only EPS8L1 and EPS8L2 activate the Rac-GEF activity of Sos-1, and bind to actin in vivo []. Eps8L2 null-mutant mice has been shown to exhibit a late-onset, progressive hearing loss that is directly linked to a gradual deterioration in hair bundle morphology []. |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
52
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
80
|
Fragment?: |
true |
|
•
•
•
•
•
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Publication |
First Author: |
Menna E |
Year: |
2009 |
Journal: |
PLoS Biol |
Title: |
Eps8 regulates axonal filopodia in hippocampal neurons in response to brain-derived neurotrophic factor (BDNF). |
Volume: |
7 |
Issue: |
6 |
Pages: |
e1000138 |
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•
•
•
•
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Publication |
First Author: |
Frittoli E |
Year: |
2011 |
Journal: |
Immunity |
Title: |
The signaling adaptor Eps8 is an essential actin capping protein for dendritic cell migration. |
Volume: |
35 |
Issue: |
3 |
Pages: |
388-99 |
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•
•
•
•
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Publication |
First Author: |
Sun J |
Year: |
2013 |
Journal: |
Zhongguo Shi Yan Xue Ye Xue Za Zhi |
Title: |
[Correlation of Eps8 with proliferation, metastasis and prognosis of malignant tumors]. |
Volume: |
21 |
Issue: |
2 |
Pages: |
493-7 |
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•
•
•
•
•
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Publication |
First Author: |
Olt J |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
The actin-binding proteins eps8 and gelsolin have complementary roles in regulating the growth and stability of mechanosensory hair bundles of mammalian cochlear outer hair cells. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e87331 |
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•
•
•
•
•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
152
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
93
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
109
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
89
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
329
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
77
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
189
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
463
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
600
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
561
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
729
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
821
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
716
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
587
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
847
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
777
|
Fragment?: |
false |
|
•
•
•
•
•
|