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Search results 101 to 190 out of 190 for Eps8l1

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0.036s
Type Details Score
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1832128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691744
Age: postnatal adult
Image: UC Davis_1858136
Specimen Label: UC Davis_1858136
Detected: true
Specimen Num: 21
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1832128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691744
Age: postnatal adult
Image: UC Davis_1858155
Specimen Label: UC Davis_1858155
Detected: true
Specimen Num: 39
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1832128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691744
Age: postnatal adult
Image: UC Davis_1858156
Specimen Label: UC Davis_1858156
Detected: true
Specimen Num: 40
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3599828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691744
Age: postnatal adult
Image: UC Davis_1858151
Specimen Label: UC Davis_1858151
Detected: true
Specimen Num: 35
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3599828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691744
Age: postnatal adult
Image: UC Davis_1858152
Specimen Label: UC Davis_1858152
Detected: true
Specimen Num: 36
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1885228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691744
Age: postnatal adult
Image: UC Davis_1858121
Specimen Label: UC Davis_1858121
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:3604860
Assay Type: RNA in situ
Annotation Date: 2005-11-17
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1752524
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:3604896
Age: embryonic day 16.5
Specimen Label: Table 1
Detected: true
Specimen Num: 5
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1752528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691744
Age: postnatal adult
Image: UC Davis_1858177
Specimen Label: UC Davis_1858177
Detected: true
Specimen Num: 55
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1752528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691744
Age: postnatal adult
Image: UC Davis_1858130
Specimen Label: UC Davis_1858130
Detected: true
Specimen Num: 15
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1752528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691744
Age: postnatal adult
Image: UC Davis_1858131
Specimen Label: UC Davis_1858131
Detected: true
Specimen Num: 16
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1752528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691744
Age: postnatal adult
Image: UC Davis_1858153
Specimen Label: UC Davis_1858153
Detected: true
Specimen Num: 37
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1752528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691744
Age: postnatal adult
Image: UC Davis_1858154
Specimen Label: UC Davis_1858154
Detected: true
Specimen Num: 38
GXD Expression      
Probe: MGI:3604860
Assay Type: RNA in situ
Annotation Date: 2005-11-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1702124
Stage: TS24
Assay Id: MGI:3604896
Age: embryonic day 16.5
Specimen Label: Table 1
Detected: false
Specimen Num: 5
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1702128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691744
Age: postnatal adult
Image: UC Davis_1858183
Specimen Label: UC Davis_1858183
Detected: true
Specimen Num: 60
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1702128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691744
Age: postnatal adult
Image: UC Davis_1858118
Specimen Label: UC Davis_1858118
Detected: true
Specimen Num: 3
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1702128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691744
Age: postnatal adult
Image: UC Davis_1858119
Specimen Label: UC Davis_1858119
Detected: true
Specimen Num: 4
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1702128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691744
Age: postnatal adult
Image: UC Davis_1858120
Specimen Label: UC Davis_1858120
Detected: true
Specimen Num: 5
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1702128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691744
Age: postnatal adult
Image: UC Davis_1858144
Specimen Label: UC Davis_1858144
Detected: true
Specimen Num: 28
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1702128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691744
Age: postnatal adult
Image: UC Davis_1858145
Specimen Label: UC Davis_1858145
Detected: true
Specimen Num: 29
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691744
Age: postnatal adult
Image: UC Davis_1858157
Specimen Label: UC Davis_1858157
Detected: true
Specimen Num: 41
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691744
Age: postnatal adult
Image: UC Davis_1858158
Specimen Label: UC Davis_1858158
Detected: true
Specimen Num: 42
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1915328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691744
Age: postnatal adult
Image: UC Davis_1858129
Specimen Label: UC Davis_1858129
Detected: true
Specimen Num: 14
GXD Expression      
Probe: MGI:3604860
Assay Type: RNA in situ
Annotation Date: 2005-11-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3273024
Stage: TS24
Assay Id: MGI:3604896
Age: embryonic day 16.5
Specimen Label: Table 1
Detected: false
Specimen Num: 5
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1757728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691744
Age: postnatal adult
Image: UC Davis_1858182
Specimen Label: UC Davis_1858182
Detected: true
Specimen Num: 59
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3281228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691744
Age: postnatal adult
Image: UC Davis_1858192
Specimen Label: UC Davis_1858192
Detected: true
Specimen Num: 64
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691744
Age: postnatal adult
Image: UC Davis_1858133
Specimen Label: UC Davis_1858133
Detected: true
Specimen Num: 18
GXD Expression      
Probe: MGI:3604860
Assay Type: RNA in situ
Annotation Date: 2005-11-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:3604896
Age: embryonic day 16.5
Specimen Label: Table 1
Detected: false
Specimen Num: 5
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691744
Age: postnatal adult
Image: UC Davis_1858172
Specimen Label: UC Davis_1858172
Detected: true
Specimen Num: 51
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1868228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691744
Age: postnatal adult
Image: UC Davis_1858186
Specimen Label: UC Davis_1858186
Detected: true
Specimen Num: 63
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Absent
Sex: Male
Emaps: EMAPS:1868228
Stage: TS28
Assay Id: MGI:6691744
Age: postnatal adult
Image: UC Davis_1858159
Specimen Label: UC Davis_1858159
Detected: false
Specimen Num: 43
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Absent
Sex: Male
Emaps: EMAPS:1868228
Stage: TS28
Assay Id: MGI:6691744
Age: postnatal adult
Image: UC Davis_1858160
Specimen Label: UC Davis_1858160
Detected: false
Specimen Num: 44
Publication
First Author: Tocchetti A
Year: 2003
Journal: Genomics
Title: In silico analysis of the EPS8 gene family: genomic organization, expression profile, and protein structure.
Volume: 81
Issue: 2
Pages: 234-44
Publication
First Author: Disanza A
Year: 2004
Journal: Nat Cell Biol
Title: Eps8 controls actin-based motility by capping the barbed ends of actin filaments.
Volume: 6
Issue: 12
Pages: 1180-8
Publication
First Author: Jung H
Year: 2018
Journal: Nat Neurosci
Title: Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice.
Volume: 21
Issue: 9
Pages: 1218-1228
Publication        
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
Publication
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
Publication        
First Author: Haiming Tang, Dustin Ebert, Matthias Blum, Robert Finn, Paul Thomas
Year: 2023
Title: TreeGrafter-generated GO annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
Publication
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication
First Author: Furness DN
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Progressive hearing loss and gradual deterioration of sensory hair bundles in the ears of mice lacking the actin-binding protein Eps8L2.
Volume: 110
Issue: 34
Pages: 13898-903
Protein Domain
Type: Family
Description: This entry includes EPS8 and EPS8L1-3 from animals.Epidermal growth factor receptor kinase substrate 8 (EPS8) is a signalling adapter that possesses actin binding, bundling, and barbed-end capping activities []. It forms a complex with Sos-1, Abi1 and the lipid kinase phosphoinositide 3-kinase (PI3-K) to regulate Rac activation that leads to actin cytoskeletal remodeling []. It is critical for dendritic cell migration []. It is involved in the initial growth of stereocilia in both inner hair cells and outer hair cells []. It also regulates axonal filopodia in hippocampal neurons in response to brain-derived neurotrophic factor (BDNF) []. It has been linked to proliferation, metastasis and prognosis of many malignant tumours [].Similarly to EPS8, EPSLs interact with Abi1 and Sos-1. However, only EPS8L1 and EPS8L2 activate the Rac-GEF activity of Sos-1, and bind to actin in vivo []. Eps8L2 null-mutant mice has been shown to exhibit a late-onset, progressive hearing loss that is directly linked to a gradual deterioration in hair bundle morphology [].
Protein
Organism: Mus musculus/domesticus
Length: 52  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 80  
Fragment?: true
Publication
First Author: Menna E
Year: 2009
Journal: PLoS Biol
Title: Eps8 regulates axonal filopodia in hippocampal neurons in response to brain-derived neurotrophic factor (BDNF).
Volume: 7
Issue: 6
Pages: e1000138
Publication
First Author: Frittoli E
Year: 2011
Journal: Immunity
Title: The signaling adaptor Eps8 is an essential actin capping protein for dendritic cell migration.
Volume: 35
Issue: 3
Pages: 388-99
Publication
First Author: Sun J
Year: 2013
Journal: Zhongguo Shi Yan Xue Ye Xue Za Zhi
Title: [Correlation of Eps8 with proliferation, metastasis and prognosis of malignant tumors].
Volume: 21
Issue: 2
Pages: 493-7
Publication
First Author: Olt J
Year: 2014
Journal: PLoS One
Title: The actin-binding proteins eps8 and gelsolin have complementary roles in regulating the growth and stability of mechanosensory hair bundles of mammalian cochlear outer hair cells.
Volume: 9
Issue: 1
Pages: e87331
Protein
Organism: Mus musculus/domesticus
Length: 152  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 93  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 109  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 89  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 329  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 77  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 189  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 463  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 600  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 561  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 729  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 821  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 716  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 587  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 847  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 777  
Fragment?: false