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Search results 401 to 479 out of 479 for Rptor

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Type Details Score
Publication
27098609 | J:236883
 
First Author: Tang Y
Year: 2016
Journal: Nat Commun
Title: Adipose tissue mTORC2 regulates ChREBP-driven de novo lipogenesis and hepatic glucose metabolism.
Volume: 7
Pages: 11365
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Publication
24662050 | J:215360
First Author: Zhao X
Year: 2014
Journal: Mol Cell Biol
Title: Phosphoinositide-dependent kinase 1 and mTORC2 synergistically maintain postnatal heart growth and heart function in mice.
Volume: 34
Issue: 11
Pages: 1966-75
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Publication
25559258 | J:259466
First Author: Shrestha S
Year: 2015
Journal: Nat Immunol
Title: Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses.
Volume: 16
Issue: 2
Pages: 178-87
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Publication
25740823 | J:220234
First Author: Carr TD
Year: 2015
Journal: Carcinogenesis
Title: Conditional disruption of rictor demonstrates a direct requirement for mTORC2 in skin tumor development and continued growth of established tumors.
Volume: 36
Issue: 4
Pages: 487-97
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Publication
23958952 | J:203260
First Author: Lee K
Year: 2013
Journal: Blood
Title: Requirement for Rictor in homeostasis and function of mature B lymphoid cells.
Volume: 122
Issue: 14
Pages: 2369-79
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Publication
25564616 | J:244133
First Author: Chen Z
Year: 2015
Journal: J Biol Chem
Title: Rictor/mTORC2 pathway in oocytes regulates folliculogenesis, and its inactivation causes premature ovarian failure.
Volume: 290
Issue: 10
Pages: 6387-96
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Publication
33388318 | J:314686
First Author: Zhao Y
Year: 2021
Journal: Gastroenterology
Title: mTORC1 and mTORC2 Converge on the Arp2/3 Complex to Promote KrasG12D-Induced Acinar-to-Ductal Metaplasia and Early Pancreatic Carcinogenesis.
Volume: 160
Issue: 5
Pages: 1755-1770.e17
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Publication
22521878 | J:184605
First Author: Hagiwara A
Year: 2012
Journal: Cell Metab
Title: Hepatic mTORC2 activates glycolysis and lipogenesis through Akt, glucokinase, and SREBP1c.
Volume: 15
Issue: 5
Pages: 725-38
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Publication
34784501 | J:321718
First Author: Gerlach BD
Year: 2021
Journal: Cell Metab
Title: Efferocytosis induces macrophage proliferation to help resolve tissue injury.
Volume: 33
Issue: 12
Pages: 2445-2463.e8
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Publication
25059582 | J:215384
First Author: Lamming DW
Year: 2014
Journal: Aging Cell
Title: Depletion of Rictor, an essential protein component of mTORC2, decreases male lifespan.
Volume: 13
Issue: 5
Pages: 911-7
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Publication
21765414 | J:176473
First Author: Yang K
Year: 2011
Journal: Nat Immunol
Title: The tumor suppressor Tsc1 enforces quiescence of naive T cells to promote immune homeostasis and function.
Volume: 12
Issue: 9
Pages: 888-97
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Publication
27690224 | J:238500
   
First Author: Yang J
Year: 2016
Journal: Elife
Title: Critical roles of mTOR Complex 1 and 2 for T follicular helper cell differentiation and germinal center responses.
Volume: 5
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Publication
25893604 | J:222700
First Author: Pollizzi KN
Year: 2015
Journal: J Clin Invest
Title: mTORC1 and mTORC2 selectively regulate CD8⁺ T cell differentiation.
Volume: 125
Issue: 5
Pages: 2090-108
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Publication
29988091 | J:282530
First Author: Newton RH
Year: 2018
Journal: Nat Immunol
Title: Maintenance of CD4 T cell fitness through regulation of Foxo1.
Volume: 19
Issue: 8
Pages: 838-848
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Publication
29425506 | J:271571
First Author: Menk AV
Year: 2018
Journal: Cell Rep
Title: Early TCR Signaling Induces Rapid Aerobic Glycolysis Enabling Distinct Acute T Cell Effector Functions.
Volume: 22
Issue: 6
Pages: 1509-1521
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Publication
22674026 | J:188431
First Author: Armour EA
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: Cystogenesis and elongated primary cilia in Tsc1-deficient distal convoluted tubules.
Volume: 303
Issue: 4
Pages: F584-92
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Publication
29232555 | J:252270
First Author: Guri Y
Year: 2017
Journal: Cancer Cell
Title: mTORC2 Promotes Tumorigenesis via Lipid Synthesis.
Volume: 32
Issue: 6
Pages: 807-823.e12
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Publication
36456551 | J:335152
First Author: Werlen G
Year: 2022
Journal: Nat Commun
Title: Dietary glucosamine overcomes the defects in αβ-T cell ontogeny caused by the loss of de novo hexosamine biosynthesis.
Volume: 13
Issue: 1
Pages: 7404
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24056770 | J:202319
First Author: Canaud G
Year: 2013
Journal: Nat Med
Title: AKT2 is essential to maintain podocyte viability and function during chronic kidney disease.
Volume: 19
Issue: 10
Pages: 1288-96
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Publication
35579957 | J:327151
 
First Author: Wong C
Year: 2022
Journal: J Clin Invest
Title: mTORC2 mediates structural plasticity in distal nociceptive endings that contributes to pain hypersensitivity following inflammation.
Volume: 132
Issue: 15
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Publication
23077666 | J:192206
First Author: Bashir T
Year: 2012
Journal: PLoS One
Title: Conditional astroglial Rictor overexpression induces malignant glioma in mice.
Volume: 7
Issue: 10
Pages: e47741
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Publication
19564418 | J:152614
First Author: Shu L
Year: 2009
Journal: Mol Cell Biol
Title: The mTORC2 complex regulates terminal differentiation of C2C12 myoblasts.
Volume: 29
Issue: 17
Pages: 4691-700
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Publication
25970154 | J:315366
First Author: Li J
Year: 2015
Journal: Kidney Int
Title: Rictor/mTORC2 signaling mediates TGFβ1-induced fibroblast activation and kidney fibrosis.
Volume: 88
Issue: 3
Pages: 515-27
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Publication
29949787 | J:318482
First Author: Qin B
Year: 2018
Journal: Cell Physiol Biochem
Title: MicroRNA-142-3p Induces Atherosclerosis-Associated Endothelial Cell Apoptosis by Directly Targeting Rictor.
Volume: 47
Issue: 4
Pages: 1589-1603
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21266327 | J:170129
First Author: Gu Y
Year: 2011
Journal: Diabetes
Title: Rictor/mTORC2 is essential for maintaining a balance between beta-cell proliferation and cell size.
Volume: 60
Issue: 3
Pages: 827-37
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30154246 | J:292349
First Author: Gui Y
Year: 2018
Journal: J Biol Chem
Title: Yap/Taz mediates mTORC2-stimulated fibroblast activation and kidney fibrosis.
Volume: 293
Issue: 42
Pages: 16364-16375
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27593484 | J:333623
First Author: Yang T
Year: 2016
Journal: Cell Mol Immunol
Title: TSC1 controls IL-1β expression in macrophages via mTORC1-dependent C/EBPβ pathway.
Volume: 13
Issue: 5
Pages: 640-50
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Publication
25175012 | J:274167
 
First Author: Zhu L
Year: 2014
Journal: Nat Commun
Title: TSC1 controls macrophage polarization to prevent inflammatory disease.
Volume: 5
Pages: 4696
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Publication
21464307 | J:171369
First Author: Xie X
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: IkappaB kinase epsilon and TANK-binding kinase 1 activate AKT by direct phosphorylation.
Volume: 108
Issue: 16
Pages: 6474-9
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Publication
29463562 | J:262092
First Author: Zhao Y
Year: 2018
Journal: Blood
Title: mTOR masters monocyte development in bone marrow by decreasing the inhibition of STAT5 on IRF8.
Volume: 131
Issue: 14
Pages: 1587-1599
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Publication
21358638 | J:170683
First Author: Delgoffe GM
Year: 2011
Journal: Nat Immunol
Title: The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2.
Volume: 12
Issue: 4
Pages: 295-303
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Publication
34031386 | J:337333
First Author: Deng J
Year: 2021
Journal: Nat Commun
Title: The metabolic hormone leptin promotes the function of T(FH) cells and supports vaccine responses.
Volume: 12
Issue: 1
Pages: 3073
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Publication
24282297 | J:205513
First Author: Wang Y
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Tuberous sclerosis 1 (Tsc1)-dependent metabolic checkpoint controls development of dendritic cells.
Volume: 110
Issue: 50
Pages: E4894-903
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Publication
22958933 | J:191342
First Author: Magee JA
Year: 2012
Journal: Cell Stem Cell
Title: Temporal changes in PTEN and mTORC2 regulation of hematopoietic stem cell self-renewal and leukemia suppression.
Volume: 11
Issue: 3
Pages: 415-28
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Publication
24280772 | J:206148
 
First Author: Byles V
Year: 2013
Journal: Nat Commun
Title: The TSC-mTOR pathway regulates macrophage polarization.
Volume: 4
Pages: 2834
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24670665 | J:210464
First Author: Signer RA
Year: 2014
Journal: Nature
Title: Haematopoietic stem cells require a highly regulated protein synthesis rate.
Volume: 509
Issue: 7498
Pages: 49-54
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Publication
27879203 | J:239173
   
First Author: Porter SN
Year: 2016
Journal: Elife
Title: Fetal and neonatal hematopoietic progenitors are functionally and transcriptionally resistant to Flt3-ITD mutations.
Volume: 5
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Publication
30201994 | J:282504
First Author: Sato R
Year: 2018
Journal: Nat Immunol
Title: Combating herpesvirus encephalitis by potentiating a TLR3-mTORC2 axis.
Volume: 19
Issue: 10
Pages: 1071-1082
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Publication
25418727 | J:338236
First Author: Lee D
Year: 2014
Journal: Stem Cell Reports
Title: Transmembrane Inhibitor of RICTOR/mTORC2 in Hematopoietic Progenitors.
Volume: 3
Issue: 5
Pages: 832-40
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Publication
30004239 | J:266128
First Author: Parker SJ
Year: 2018
Journal: Am J Physiol Heart Circ Physiol
Title: Proteomics reveals Rictor as a noncanonical TGF-β signaling target during aneurysm progression in Marfan mice.
Volume: 315
Issue: 5
Pages: H1112-H1126
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Publication
18426911 | J:137298
First Author: Hagan GN
Year: 2008
Journal: Mol Cell Biol
Title: A Rictor-Myo1c complex participates in dynamic cortical actin events in 3T3-L1 adipocytes.
Volume: 28
Issue: 13
Pages: 4215-26
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Publication
31442424 | J:281991
First Author: Jung SM
Year: 2019
Journal: Mol Cell
Title: Non-canonical mTORC2 Signaling Regulates Brown Adipocyte Lipid Catabolism through SIRT6-FoxO1.
Volume: 75
Issue: 4
Pages: 807-822.e8
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Publication
26437242 | J:260120
First Author: Charbonnier LM
Year: 2015
Journal: Nat Immunol
Title: Control of peripheral tolerance by regulatory T cell-intrinsic Notch signaling.
Volume: 16
Issue: 11
Pages: 1162-73
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Publication
31996678 | J:289858
First Author: Martinez Calejman C
Year: 2020
Journal: Nat Commun
Title: mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis.
Volume: 11
Issue: 1
Pages: 575
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Publication
32289155 | J:288638
 
First Author: Raynor JL
Year: 2020
Journal: J Exp Med
Title: Hippo/Mst signaling coordinates cellular quiescence with terminal maturation in iNKT cell development and fate decisions.
Volume: 217
Issue: 6
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Publication
34623920 | J:338433
First Author: Liu C
Year: 2021
Journal: Sci Adv
Title: Glycogen synthase kinase 3 drives thymocyte egress by suppressing β-catenin activation of Akt.
Volume: 7
Issue: 41
Pages: eabg6262
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Publication
23979601 | J:205424
First Author: McGuire VA
Year: 2013
Journal: Mol Cell Biol
Title: Cross talk between the Akt and p38α pathways in macrophages downstream of Toll-like receptor signaling.
Volume: 33
Issue: 21
Pages: 4152-65
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Publication
16221682 | J:104099
First Author: Hresko RC
Year: 2005
Journal: J Biol Chem
Title: mTOR.RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes.
Volume: 280
Issue: 49
Pages: 40406-16
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16962653 | J:125618
First Author: Jacinto E
Year: 2006
Journal: Cell
Title: SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity.
Volume: 127
Issue: 1
Pages: 125-37
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Publication
25377878 | J:232620
First Author: Tao R
Year: 2015
Journal: Diabetes
Title: Sestrin 3 protein enhances hepatic insulin sensitivity by direct activation of the mTORC2-Akt signaling.
Volume: 64
Issue: 4
Pages: 1211-23
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Publication
19995915 | J:160501
First Author: Julien LA
Year: 2010
Journal: Mol Cell Biol
Title: mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling.
Volume: 30
Issue: 4
Pages: 908-21
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Publication
22307628 | J:182033
First Author: Zhang C
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Glycerolipid signals alter mTOR complex 2 (mTORC2) to diminish insulin signaling.
Volume: 109
Issue: 5
Pages: 1667-72
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20832730 | J:163988
First Author: Gao D
Year: 2010
Journal: Mol Cell
Title: Rictor forms a complex with Cullin-1 to promote SGK1 ubiquitination and destruction.
Volume: 39
Issue: 5
Pages: 797-808
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Publication
21329883 | J:170850
First Author: Ou YH
Year: 2011
Journal: Mol Cell
Title: TBK1 directly engages Akt/PKB survival signaling to support oncogenic transformation.
Volume: 41
Issue: 4
Pages: 458-70
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23852728 | J:198782
First Author: Betz C
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Feature Article: mTOR complex 2-Akt signaling at mitochondria-associated endoplasmic reticulum membranes (MAM) regulates mitochondrial physiology.
Volume: 110
Issue: 31
Pages: 12526-34
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Publication
29996106 | J:271145
First Author: Akgül S
Year: 2018
Journal: Cell Rep
Title: Opposing Tumor-Promoting and -Suppressive Functions of Rictor/mTORC2 Signaling in Adult Glioma and Pediatric SHH Medulloblastoma.
Volume: 24
Issue: 2
Pages: 463-478.e5
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Publication
30154443 | J:302784
First Author: Zhu Y
Year: 2019
Journal: Cell Death Differ
Title: Superhero Rictor promotes cellular differentiation of mouse embryonic stem cells.
Volume: 26
Issue: 5
Pages: 958-968
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Publication
33307020 | J:302126
First Author: Inomata M
Year: 2021
Journal: Exp Cell Res
Title: Rictor-targeting exosomal microRNA-16 ameliorates lung fibrosis by inhibiting the mTORC2-SPARC axis.
Volume: 398
Issue: 2
Pages: 112416
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Publication
28106162 | J:323752
 
First Author: Chen WY
Year: 2017
Journal: Sci Rep
Title: Heterogeneous nuclear ribonucleoprotein M associates with mTORC2 and regulates muscle differentiation.
Volume: 7
Pages: 41159
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Publication
22057724 | J:321353
First Author: Zhang Z
Year: 2012
Journal: Mol Cell Biochem
Title: mTOR-rictor is the Ser473 kinase for AKT1 in mouse one-cell stage embryos.
Volume: 361
Issue: 1-2
Pages: 249-57
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Publication
16962829 | J:119564
First Author: Shiota C
Year: 2006
Journal: Dev Cell
Title: Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability.
Volume: 11
Issue: 4
Pages: 583-9
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24939733 | J:215498
First Author: Zhang C
Year: 2014
Journal: Am J Physiol Endocrinol Metab
Title: Glycerol-3-phosphate acyltransferase-4-deficient mice are protected from diet-induced insulin resistance by the enhanced association of mTOR and rictor.
Volume: 307
Issue: 3
Pages: E305-15
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Publication
26923591 | J:234363
First Author: Micevic G
Year: 2016
Journal: Cell Rep
Title: DNMT3b Modulates Melanoma Growth by Controlling Levels of mTORC2 Component RICTOR.
Volume: 14
Issue: 9
Pages: 2180-2192
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22399812 | J:197817
First Author: Lamouille S
Year: 2012
Journal: J Cell Sci
Title: TGF-β-induced activation of mTOR complex 2 drives epithelial-mesenchymal transition and cell invasion.
Volume: 125
Issue: Pt 5
Pages: 1259-73
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Publication
26453307 | J:228576
First Author: Singh BK
Year: 2016
Journal: J Biol Chem
Title: Hepatic FOXO1 Target Genes Are Co-regulated by Thyroid Hormone via RICTOR Protein Deacetylation and MTORC2-AKT Protein Inhibition.
Volume: 291
Issue: 1
Pages: 198-214
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18925875 | J:144578
First Author: García-Martínez JM
Year: 2008
Journal: Biochem J
Title: mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1).
Volume: 416
Issue: 3
Pages: 375-85
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Publication
22550181 | J:184787
First Author: Kaur S
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Regulatory effects of mTORC2 complexes in type I IFN signaling and in the generation of IFN responses.
Volume: 109
Issue: 20
Pages: 7723-8
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Publication
26645692 | J:230930
First Author: Kroczynska B
Year: 2016
Journal: J Biol Chem
Title: Interferon γ (IFNγ) Signaling via Mechanistic Target of Rapamycin Complex 2 (mTORC2) and Regulatory Effects in the Generation of Type II Interferon Biological Responses.
Volume: 291
Issue: 5
Pages: 2389-96
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15268862 | J:320275
First Author: Sarbassov DD
Year: 2004
Journal: Curr Biol
Title: Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton.
Volume: 14
Issue: 14
Pages: 1296-302
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Publication
18566586 | J:137614
First Author: Facchinetti V
Year: 2008
Journal: EMBO J
Title: The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C.
Volume: 27
Issue: 14
Pages: 1932-43
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29213092 | J:259795
First Author: Green RM
Year: 2017
Journal: Nat Commun
Title: Developmental nonlinearity drives phenotypic robustness.
Volume: 8
Issue: 1
Pages: 1970
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21413931 | J:172256
First Author: Pearce LR
Year: 2011
Journal: Biochem J
Title: Protor-1 is required for efficient mTORC2-mediated activation of SGK1 in the kidney.
Volume: 436
Issue: 1
Pages: 169-79
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Publication
36220823 | J:329956
First Author: Wan S
Year: 2022
Journal: Cell Death Dis
Title: mTORC1 signaling pathway integrates estrogen and growth factor to coordinate vaginal epithelial cells proliferation and differentiation.
Volume: 13
Issue: 10
Pages: 862
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31420305 | J:295751
 
First Author: Mazier W
Year: 2019
Journal: Mol Metab
Title: mTORC1 and CB1 receptor signaling regulate excitatory glutamatergic inputs onto the hypothalamic paraventricular nucleus in response to energy availability.
Volume: 28
Pages: 151-159
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35918345 | J:327158
First Author: Silva J
Year: 2022
Journal: Nat Commun
Title: Ribosome impairment regulates intestinal stem cell identity via ZAKɑ activation.
Volume: 13
Issue: 1
Pages: 4492
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Publication
26633882 | J:269511
   
First Author: Roy A
Year: 2015
Journal: Elife
Title: Mouse models of human PIK3CA-related brain overgrowth have acutely treatable epilepsy.
Volume: 4
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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