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Search results 101 to 200 out of 240 for Alox5

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Category: Publication
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Type Details Score
Publication
20031637 | J:182797
First Author: Wang SS
Year: 2009
Journal: Circ Cardiovasc Genet
Title: Disruption of the aortic elastic lamina and medial calcification share genetic determinants in mice.
Volume: 2
Issue: 6
Pages: 573-82
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Publication
22696442 | J:189546
First Author: Serezani CH
Year: 2012
Journal: J Immunol
Title: Macrophage dectin-1 expression is controlled by leukotriene B4 via a GM-CSF/PU.1 axis.
Volume: 189
Issue: 2
Pages: 906-15
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Publication
29311656 | J:259273
First Author: Ibarra-Soria X
Year: 2018
Journal: Nat Cell Biol
Title: Defining murine organogenesis at single-cell resolution reveals a role for the leukotriene pathway in regulating blood progenitor formation.
Volume: 20
Issue: 2
Pages: 127-134
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Publication
24743022 | J:212558
First Author: da Silva-Souza HA
Year: 2014
Journal: Biochim Biophys Acta
Title: Inhibitors of the 5-lipoxygenase arachidonic acid pathway induce ATP release and ATP-dependent organic cation transport in macrophages.
Volume: 1838
Issue: 7
Pages: 1967-77
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Publication
26663781 | J:256646
First Author: Poczobutt JM
Year: 2016
Journal: J Immunol
Title: Deletion of 5-Lipoxygenase in the Tumor Microenvironment Promotes Lung Cancer Progression and Metastasis through Regulating T Cell Recruitment.
Volume: 196
Issue: 2
Pages: 891-901
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Publication
21206089 | J:171834
First Author: Serezani CH
Year: 2011
Journal: J Clin Invest
Title: Leukotriene B4 amplifies NF-κB activation in mouse macrophages by reducing SOCS1 inhibition of MyD88 expression.
Volume: 121
Issue: 2
Pages: 671-82
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Publication
28383037 | J:276110
 
First Author: Li JG
Year: 2017
Journal: Sci Rep
Title: Five lipoxygenase hypomethylation mediates the homocysteine effect on Alzheimer's phenotype.
Volume: 7
Pages: 46002
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Publication
17982097 | J:153854
First Author: Swindle EJ
Year: 2007
Journal: J Immunol
Title: FcepsilonRI- and Fcgamma receptor-mediated production of reactive oxygen species by mast cells is lipoxygenase- and cyclooxygenase-dependent and NADPH oxidase-independent.
Volume: 179
Issue: 10
Pages: 7059-71
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Publication
25628460 | J:260291
First Author: Filgueiras LR
Year: 2015
Journal: Sci Signal
Title: Leukotriene B4-mediated sterile inflammation promotes susceptibility to sepsis in a mouse model of type 1 diabetes.
Volume: 8
Issue: 361
Pages: ra10
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Publication
23859654 | J:231558
First Author: Ochkur SI
Year: 2013
Journal: Am J Respir Cell Mol Biol
Title: Cys-leukotrienes promote fibrosis in a mouse model of eosinophil-mediated respiratory inflammation.
Volume: 49
Issue: 6
Pages: 1074-84
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Publication
19509298 | J:153174
First Author: Poeckel D
Year: 2009
Journal: J Biol Chem
Title: Dual 12/15- and 5-lipoxygenase deficiency in macrophages alters arachidonic acid metabolism and attenuates peritonitis and atherosclerosis in ApoE knock-out mice.
Volume: 284
Issue: 31
Pages: 21077-89
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Publication
30185672 | J:285254
 
First Author: Brandt SL
Year: 2018
Journal: JCI Insight
Title: Excessive localized leukotriene B4 levels dictate poor skin host defense in diabetic mice.
Volume: 3
Issue: 17
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Publication
30102746 | J:325510
First Author: Brandt SL
Year: 2018
Journal: PLoS Pathog
Title: Macrophage-derived LTB4 promotes abscess formation and clearance of Staphylococcus aureus skin infection in mice.
Volume: 14
Issue: 8
Pages: e1007244
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Publication
16624897 | J:109792
First Author: Ghazalpour A
Year: 2006
Journal: Genetics
Title: Complex inheritance of the 5-lipoxygenase locus influencing atherosclerosis in mice.
Volume: 173
Issue: 2
Pages: 943-51
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Publication
17979156 | J:128427
First Author: Verri WA Jr
Year: 2007
Journal: Eur J Immunol
Title: IL-15 mediates antigen-induced neutrophil migration by triggering IL-18 production.
Volume: 37
Issue: 12
Pages: 3373-80
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Publication
32854115 | J:306353
 
First Author: Subramanian BC
Year: 2020
Journal: J Cell Biol
Title: The LTB4-BLT1 axis regulates actomyosin and β2-integrin dynamics during neutrophil extravasation.
Volume: 219
Issue: 10
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Publication
24747745 | J:213239
First Author: Chen M
Year: 2014
Journal: Nat Med
Title: Essential role for autophagy in the maintenance of immunological memory against influenza infection.
Volume: 20
Issue: 5
Pages: 503-10
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Publication
23809162 | J:207575
First Author: Yan Y
Year: 2013
Journal: Immunity
Title: Omega-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation.
Volume: 38
Issue: 6
Pages: 1154-63
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Publication
31300449 | J:294670
First Author: Du F
Year: 2019
Journal: Clin Cancer Res
Title: Leukotriene Synthesis Is Critical for Medulloblastoma Progression.
Volume: 25
Issue: 21
Pages: 6475-6486
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Publication
19299700 | J:147134
First Author: Sorgi CA
Year: 2009
Journal: J Immunol
Title: Histoplasma capsulatum cell wall {beta}-glucan induces lipid body formation through CD18, TLR2, and dectin-1 receptors: correlation with leukotriene B4 generation and role in HIV-1 infection.
Volume: 182
Issue: 7
Pages: 4025-35
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Publication
25698732 | J:219863
First Author: Rudhard Y
Year: 2015
Journal: J Neurosci
Title: Identification of 12/15-lipoxygenase as a regulator of axon degeneration through high-content screening.
Volume: 35
Issue: 7
Pages: 2927-41
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Publication
20219953 | J:160350
First Author: Queto T
Year: 2010
Journal: J Leukoc Biol
Title: Cysteinyl-leukotriene type 1 receptors transduce a critical signal for the up-regulation of eosinophilopoiesis by interleukin-13 and eotaxin in murine bone marrow.
Volume: 87
Issue: 5
Pages: 885-93
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Publication
32234475 | J:287654
First Author: Rahabi M
Year: 2020
Journal: Cell Rep
Title: Divergent Roles for Macrophage C-type Lectin Receptors, Dectin-1 and Mannose Receptors, in the Intestinal Inflammatory Response.
Volume: 30
Issue: 13
Pages: 4386-4398.e5
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Publication
24889202 | J:214462
First Author: Patnode ML
Year: 2014
Journal: J Exp Med
Title: Leukotriene B4 amplifies eosinophil accumulation in response to nematodes.
Volume: 211
Issue: 7
Pages: 1281-8
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Publication
28108297 | J:240735
First Author: Sezin T
Year: 2017
Journal: J Invest Dermatol
Title: The Leukotriene B4 and its Receptor BLT1 Act as Critical Drivers of Neutrophil Recruitment in Murine Bullous Pemphigoid-Like Epidermolysis Bullosa Acquisita.
Volume: 137
Issue: 5
Pages: 1104-1113
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Publication
21307302 | J:171000
First Author: Sapieha P
Year: 2011
Journal: Sci Transl Med
Title: 5-Lipoxygenase metabolite 4-HDHA is a mediator of the antiangiogenic effect of ω-3 polyunsaturated fatty acids.
Volume: 3
Issue: 69
Pages: 69ra12
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Publication
23485965 | J:195129
First Author: Hoggatt J
Year: 2013
Journal: Nature
Title: Differential stem- and progenitor-cell trafficking by prostaglandin E2.
Volume: 495
Issue: 7441
Pages: 365-9
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Publication
28011865 | J:238774
First Author: von Moltke J
Year: 2017
Journal: J Exp Med
Title: Leukotrienes provide an NFAT-dependent signal that synergizes with IL-33 to activate ILC2s.
Volume: 214
Issue: 1
Pages: 27-37
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Publication
36599368 | J:340014
First Author: Pernet E
Year: 2023
Journal: Nature
Title: Neonatal imprinting of alveolar macrophages via neutrophil-derived 12-HETE.
Volume: 614
Issue: 7948
Pages: 530-538
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15240672 | J:91926
First Author: Yopp AC
Year: 2004
Journal: J Immunol
Title: FTY720-enhanced T cell homing is dependent on CCR2, CCR5, CCR7, and CXCR4: evidence for distinct chemokine compartments.
Volume: 173
Issue: 2
Pages: 855-65
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Publication
25779634 | J:222287
First Author: Cheng LE
Year: 2015
Journal: J Exp Med
Title: IgE-activated basophils regulate eosinophil tissue entry by modulating endothelial function.
Volume: 212
Issue: 4
Pages: 513-24
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Publication
18344982 | J:134171
First Author: Chen Y
Year: 2008
Journal: Nature
Title: Variations in DNA elucidate molecular networks that cause disease.
Volume: 452
Issue: 7186
Pages: 429-35
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Publication
23112187 | J:191734
First Author: Sadik CD
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Neutrophils orchestrate their own recruitment in murine arthritis through C5aR and FcγR signaling.
Volume: 109
Issue: 46
Pages: E3177-85
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Publication
24990750 | J:213640
First Author: Mayer-Barber KD
Year: 2014
Journal: Nature
Title: Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk.
Volume: 511
Issue: 7507
Pages: 99-103
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7809134 | J:68714
First Author: Goulet JL
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: Altered inflammatory responses in leukotriene-deficient mice.
Volume: 91
Issue: 26
Pages: 12852-6
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Publication
29106033 | J:256429
 
First Author: Vagnozzi AN
Year: 2018
Journal: Aging Cell
Title: Brain 5-lipoxygenase over-expression worsens memory, synaptic integrity, and tau pathology in the P301S mice.
Volume: 17
Issue: 1
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Publication
11714834 | J:72819
First Author: Goulet JL
Year: 2001
Journal: J Immunol
Title: Deficiency of 5-lipoxygenase accelerates renal allograft rejection in mice.
Volume: 167
Issue: 11
Pages: 6631-6
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Publication
15549416 | J:99471
First Author: Rosen CJ
Year: 2005
Journal: Pediatr Nephrol
Title: Allelic differences in a quantitative trait locus affecting insulin-like growth factor-I impact skeletal acquisition and body composition.
Volume: 20
Issue: 3
Pages: 255-60
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Publication
21435457 | J:169845
First Author: Chu J
Year: 2011
Journal: Am J Pathol
Title: Pharmacologic blockade of 5-lipoxygenase improves the amyloidotic phenotype of an Alzheimer's disease transgenic mouse model involvement of γ-secretase.
Volume: 178
Issue: 4
Pages: 1762-9
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Publication
12140292 | J:79448
First Author: Jones SM
Year: 2002
Journal: J Biol Chem
Title: Structural and functional criteria reveal a new nuclear import sequence on the 5-lipoxygenase protein.
Volume: 277
Issue: 41
Pages: 38550-6
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Publication
11027682 | J:66824
First Author: Schwarz K
Year: 2001
Journal: J Biol Chem
Title: Structural basis for lipoxygenase specificity. Conversion of the human leukocyte 5-lipoxygenase to a 15-lipoxygenating enzyme species by site-directed mutagenesis.
Volume: 276
Issue: 1
Pages: 773-9
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Publication
11042125 | J:65666
 
First Author: Zhang YY
Year: 2000
Journal: Biochem J
Title: Analysis of a nucleotide-binding site of 5-lipoxygenase by affinity labelling: binding characteristics and amino acid sequences.
Volume: 351 Pt 3
Pages: 697-707
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Publication
7732821 | J:26264
 
First Author: Funk CD
Year: 1995
Journal: Adv Prostaglandin Thromboxane Leukot Res
Title: Leukotriene-deficient mice generated by targeted disruption of the 5-lipoxygenase gene.
Volume: 23
Pages: 145-50
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Publication
16024599 | J:100088
First Author: Hennig R
Year: 2005
Journal: Cancer Res
Title: 5-Lipoxygenase, a marker for early pancreatic intraepithelial neoplastic lesions.
Volume: 65
Issue: 14
Pages: 6011-6
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Publication
16645143 | J:121398
First Author: Lyons MA
Year: 2006
Journal: Circ Res
Title: Arachidonate 5-lipoxygenase variants in atherosclerosis, obesity, and bone traits.
Volume: 98
Issue: 8
Pages: e66
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Publication
20851170 | J:169715
First Author: Chen H
Year: 2010
Journal: Neuroscience
Title: 5-Lipoxygenase in mouse cerebellar Purkinje cells.
Volume: 171
Issue: 2
Pages: 383-9
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Publication
21558275 | J:177003
First Author: Schurmann K
Year: 2011
Journal: J Biol Chem
Title: Molecular basis for the reduced catalytic activity of the naturally occurring T560M mutant of human 12/15-lipoxygenase that has been implicated in coronary artery disease.
Volume: 286
Issue: 27
Pages: 23920-7
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Publication
21951814 | J:189469
First Author: Walther M
Year: 2011
Journal: Arch Biochem Biophys
Title: The N-terminal β-barrel domain of mammalian lipoxygenases including mouse 5-lipoxygenase is not essential for catalytic activity and membrane binding but exhibits regulatory functions.
Volume: 516
Issue: 1
Pages: 1-9
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Publication
23381993 | J:194048
First Author: Tristão FS
Year: 2013
Journal: Infect Immun
Title: 5-Lipoxygenase activity increases susceptibility to experimental Paracoccidioides brasiliensis infection.
Volume: 81
Issue: 4
Pages: 1256-66
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Publication
34896181 | J:319776
 
First Author: Barbosa-Silva MC
Year: 2022
Journal: Brain Behav Immun
Title: Mice lacking 5-lipoxygenase display motor deficits associated with cortical and hippocampal synapse abnormalities.
Volume: 100
Pages: 183-193
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Publication
36216800 | J:329944
First Author: Pamplona FA
Year: 2022
Journal: Transl Psychiatry
Title: Age-linked suppression of lipoxin A4 associates with cognitive deficits in mice and humans.
Volume: 12
Issue: 1
Pages: 439
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Publication
19734227 | J:152787
First Author: McKee AS
Year: 2009
Journal: J Immunol
Title: Alum induces innate immune responses through macrophage and mast cell sensors, but these sensors are not required for alum to act as an adjuvant for specific immunity.
Volume: 183
Issue: 7
Pages: 4403-14
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Publication
33450207 | J:301435
First Author: Wang F
Year: 2021
Journal: Cell
Title: A basophil-neuronal axis promotes itch.
Volume: 184
Issue: 2
Pages: 422-440.e17
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32160525 | J:288632
First Author: McGinty JW
Year: 2020
Journal: Immunity
Title: Tuft-Cell-Derived Leukotrienes Drive Rapid Anti-helminth Immunity in the Small Intestine but Are Dispensable for Anti-protist Immunity.
Volume: 52
Issue: 3
Pages: 528-541.e7
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12021253 | J:76645
First Author: Fabre JE
Year: 2002
Journal: J Clin Invest
Title: Transcellular biosynthesis contributes to the production of leukotrienes during inflammatory responses in vivo.
Volume: 109
Issue: 10
Pages: 1373-80
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19075240 | J:142670
First Author: Mandal AK
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: The nuclear membrane organization of leukotriene synthesis.
Volume: 105
Issue: 51
Pages: 20434-9
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17392829 | J:122095
First Author: Doepping S
Year: 2007
Journal: J Invest Dermatol
Title: Selective 5-lipoxygenase expression in Langerhans cells and impaired dendritic cell migration in 5-LO-deficient mice reveal leukotriene action in skin.
Volume: 127
Issue: 7
Pages: 1692-700
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28694473 | J:253033
First Author: Kwak HJ
Year: 2017
Journal: Sci Rep
Title: 5-LO inhibition ameliorates palmitic acid-induced ER stress, oxidative stress and insulin resistance via AMPK activation in murine myotubes.
Volume: 7
Issue: 1
Pages: 5025
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Publication
27896923 | J:239960
First Author: Li JG
Year: 2017
Journal: Aging Cell
Title: Homocysteine modulates 5-lipoxygenase expression level via DNA methylation.
Volume: 16
Issue: 2
Pages: 273-280
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Publication
25802082 | J:284340
First Author: Giannopoulos PF
Year: 2015
Journal: Biol Psychiatry
Title: Pharmacologic inhibition of 5-lipoxygenase improves memory, rescues synaptic dysfunction, and ameliorates tau pathology in a transgenic model of tauopathy.
Volume: 78
Issue: 10
Pages: 693-701
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Publication
20876351 | J:165193
First Author: Chen M
Year: 2010
Journal: J Immunol
Title: Joint tissues amplify inflammation and alter their invasive behavior via leukotriene B4 in experimental inflammatory arthritis.
Volume: 185
Issue: 9
Pages: 5503-11
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19416808 | J:148535
First Author: Zarini S
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Transcellular biosynthesis of cysteinyl leukotrienes in vivo during mouse peritoneal inflammation.
Volume: 106
Issue: 20
Pages: 8296-301
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10384136 | J:55637
First Author: Goulet JL
Year: 1999
Journal: J Immunol
Title: Deficiency of 5-lipoxygenase abolishes sex-related survival differences in MRL-lpr/lpr mice.
Volume: 163
Issue: 1
Pages: 359-66
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16567388 | J:123751
First Author: Chen M
Year: 2006
Journal: J Exp Med
Title: Neutrophil-derived leukotriene B4 is required for inflammatory arthritis.
Volume: 203
Issue: 4
Pages: 837-42
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9091580 | J:39229
First Author: Byrum RS
Year: 1997
Journal: J Exp Med
Title: Role of the 5-lipoxygenase-activating protein (FLAP) in murine acute inflammatory responses.
Volume: 185
Issue: 6
Pages: 1065-75
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23408836 | J:193679
First Author: Wejksza K
Year: 2013
Journal: J Immunol
Title: Cancer-produced metabolites of 5-lipoxygenase induce tumor-evoked regulatory B cells via peroxisome proliferator-activated receptor α.
Volume: 190
Issue: 6
Pages: 2575-84
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8944751 | J:36801
First Author: Funk CD
Year: 1996
Journal: Biochim Biophys Acta
Title: The molecular biology of mammalian lipoxygenases and the quest for eicosanoid functions using lipoxygenase-deficient mice.
Volume: 1304
Issue: 1
Pages: 65-84
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9088981 | J:39220
First Author: Edmiston JS
Year: 1997
Journal: Int Immunol
Title: A transforming growth factor-beta regulable RNA-binding protein interacts specifically with germline Ig alpha transcripts.
Volume: 9
Issue: 3
Pages: 427-33
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16081317 | J:100528
First Author: Lötzer K
Year: 2005
Journal: Biochim Biophys Acta
Title: The 5-lipoxygenase pathway in arterial wall biology and atherosclerosis.
Volume: 1736
Issue: 1
Pages: 30-7
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19135147 | J:145692
First Author: Yun MR
Year: 2009
Journal: Free Radic Biol Med
Title: 4-Hydroxynonenal enhances CD36 expression on murine macrophages via p38 MAPK-mediated activation of 5-lipoxygenase.
Volume: 46
Issue: 5
Pages: 692-8
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19965960 | J:176111
First Author: Finkensieper A
Year: 2010
Journal: Cardiovasc Res
Title: The 5-lipoxygenase pathway regulates vasculogenesis in differentiating mouse embryonic stem cells.
Volume: 86
Issue: 1
Pages: 37-44
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Publication
23708969 | J:198733
First Author: Lämmermann T
Year: 2013
Journal: Nature
Title: Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo.
Volume: 498
Issue: 7454
Pages: 371-5
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24332986 | J:212730
First Author: Joshi YB
Year: 2014
Journal: Neurobiol Aging
Title: Modulation of lipopolysaccharide-induced memory insult, γ-secretase, and neuroinflammation in triple transgenic mice by 5-lipoxygenase.
Volume: 35
Issue: 5
Pages: 1024-31
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23634895 | J:214888
First Author: Joshi YB
Year: 2013
Journal: Aging Cell
Title: Knockout of 5-lipoxygenase prevents dexamethasone-induced tau pathology in 3xTg mice.
Volume: 12
Issue: 4
Pages: 706-11
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16698924 | J:110208
First Author: Qiu H
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Expression of 5-lipoxygenase and leukotriene A4 hydrolase in human atherosclerotic lesions correlates with symptoms of plaque instability.
Volume: 103
Issue: 21
Pages: 8161-6
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19561612 | J:151654
First Author: Divangahi M
Year: 2009
Journal: Nat Immunol
Title: Mycobacterium tuberculosis evades macrophage defenses by inhibiting plasma membrane repair.
Volume: 10
Issue: 8
Pages: 899-906
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20622882 | J:162390
First Author: Divangahi M
Year: 2010
Journal: Nat Immunol
Title: Eicosanoid pathways regulate adaptive immunity to Mycobacterium tuberculosis.
Volume: 11
Issue: 8
Pages: 751-8
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17404289 | J:122128
First Author: Wielockx B
Year: 2007
Journal: J Immunol
Title: Description and mapping of the resistance of DBA/2 mice to TNF-induced lethal shock.
Volume: 178
Issue: 8
Pages: 5069-75
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17761955 | J:129968
First Author: Coffey MJ
Year: 2007
Journal: J Leukoc Biol
Title: NADPH oxidase deficiency results in reduced alveolar macrophage 5-lipoxygenase expression and decreased leukotriene synthesis.
Volume: 82
Issue: 6
Pages: 1585-91
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Publication
23109727 | J:190666
First Author: Lee JM
Year: 2012
Journal: J Immunol
Title: 5-Lipoxygenase mediates RANKL-induced osteoclast formation via the cysteinyl leukotriene receptor 1.
Volume: 189
Issue: 11
Pages: 5284-92
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Publication
25246560 | J:216465
First Author: Fredman G
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Resolvin D1 limits 5-lipoxygenase nuclear localization and leukotriene B4 synthesis by inhibiting a calcium-activated kinase pathway.
Volume: 111
Issue: 40
Pages: 14530-5
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Publication
27060751 | J:248836
 
First Author: Joshi V
Year: 2016
Journal: Arch Biochem Biophys
Title: Dimethyl ester of bilirubin exhibits anti-inflammatory activity through inhibition of secretory phospholipase A2, lipoxygenase and cyclooxygenase.
Volume: 598
Pages: 28-39
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22493243 | J:183843
First Author: Yu Z
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Disruption of the 5-lipoxygenase pathway attenuates atherogenesis consequent to COX-2 deletion in mice.
Volume: 109
Issue: 17
Pages: 6727-32
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