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Search results 101 to 185 out of 185 for Lars

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Type Details Score
Allele
H2-Oa<tm1Lkar> | MGI:2675254
Name: histocompatibility 2, O region alpha locus; targeted mutation 1, Lars Karlsson
Allele Type: Targeted
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: Nrg1/Nrg1
Background: involves: 129S1/Sv * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nrg1/Nrg1
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(HLA-DR2)#Lfug/? Tg(TCROb.1A12)#Lfug/?
Background: involves: C57BL/6 * DBA/2
Zygosity: cx
Has Mutant Allele: true
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Protein Coding Gene
MGI:1913808 | Lars1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
17572677 | J:123353
First Author: Hoffmann A
Year: 2007
Journal: Nat Immunol
Title: Siglec-G is a B1 cell-inhibitory receptor that controls expansion and calcium signaling of the B1 cell population.
Volume: 8
Issue: 7
Pages: 695-704
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Publication
20729333 | J:163534
First Author: Jellusova J
Year: 2010
Journal: J Immunol
Title: Siglec-G regulates B1 cell survival and selection.
Volume: 185
Issue: 6
Pages: 3277-84
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Publication
24859880 | J:320824
First Author: Simonetti G
Year: 2014
Journal: Haematologica
Title: SIGLEC-G deficiency increases susceptibility to develop B-cell lymphoproliferative disorders.
Volume: 99
Issue: 8
Pages: 1356-64
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Publication
9342050 | J:43309
First Author: Meyer D
Year: 1997
Journal: Development
Title: Isoform-specific expression and function of neuregulin.
Volume: 124
Issue: 18
Pages: 3575-86
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Strain
MGI:7608055 | C57BL/6-Lamp5<em1Lmit>
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Publication
8638109 | J:31786
First Author: Fung-Leung WP
Year: 1996
Journal: Science
Title: Antigen presentation and T cell development in H2-M-deficient mice.
Volume: 271
Issue: 5253
Pages: 1278-81
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Publication
10023773 | J:110458
First Author: Lee DS
Year: 1999
Journal: Immunity
Title: Thymic selection by a single MHC/peptide ligand: autoreactive T cells are low-affinity cells.
Volume: 10
Issue: 1
Pages: 83-92
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Publication
11714799 | J:72827
First Author: Alfonso C
Year: 2001
Journal: J Immunol
Title: The impact of H2-DM on humoral immune responses.
Volume: 167
Issue: 11
Pages: 6348-55
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Publication
11160315 | J:119484
First Author: Nitschke L
Year: 2001
Journal: J Immunol
Title: Deletion of the DQ52 element within the Ig heavy chain locus leads to a selective reduction in VDJ recombination and altered D gene usage.
Volume: 166
Issue: 4
Pages: 2540-52
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Strain
MGI:5568396 | B6.C(Cg)-Grb2<tm1.1Lnit>/J
Attribute String: congenic, mutant strain, targeted mutation
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Publication
26983787 | J:238327
First Author: Krzyzak L
Year: 2016
Journal: J Immunol
Title: CD83 Modulates B Cell Activation and Germinal Center Responses.
Volume: 196
Issue: 9
Pages: 3581-94
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Publication
36875129 | J:335138
 
First Author: Peckert-Maier K
Year: 2023
Journal: Front Immunol
Title: CD83 expressed by macrophages is an important immune checkpoint molecule for the resolution of inflammation.
Volume: 14
Pages: 1085742
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Publication
9492004 | J:85084
First Author: Liljedahl M
Year: 1998
Journal: Immunity
Title: Altered antigen presentation in mice lacking H2-O.
Volume: 8
Issue: 2
Pages: 233-43
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Publication
11466355 | J:120491
First Author: Qi L
Year: 2001
Journal: J Immunol
Title: H2-O inhibits presentation of bacterial superantigens, but not endogenous self antigens.
Volume: 167
Issue: 3
Pages: 1371-8
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Publication
16517723 | J:129508
First Author: Chen X
Year: 2006
Journal: J Immunol
Title: H2-O expression in primary dendritic cells.
Volume: 176
Issue: 6
Pages: 3548-56
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Publication
23209323 | J:190823
First Author: Gu Y
Year: 2013
Journal: J Immunol
Title: Immunodeficiency and autoimmunity in H2-O-deficient mice.
Volume: 190
Issue: 1
Pages: 126-37
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Genotype
Genotype
Symbol: H2-Oa/H2-Oa
Background: involves: 129P2/OlaHsd
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nrg1/Nrg1<+>
Background: involves: 129S1/Sv * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: H2-DMa/H2-DMa
Background: involves: 129P2/OlaHsd
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Igh/Igh<+>
Background: involves: BALB/c * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Siglecg/Siglecg
Background: involves: BALB/c
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Cd4-CD4)2362Litt/? Tg(HLA-DR2)#Lfug/? Tg(TCROb.1A12)#Lfug/?
Background: involves: C57BL/6 * DBA/2 * SJL
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fam181b/Fam181b
Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6N
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(tetO-TARDBP*A315T)13Lmit/? Tg(Thy1-tTA)6Lmit/?
Background: involves: C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(tetO-TARDBP*A315T)13Lmit/? Tg(Thy1-tTA)15Lmit/?
Background: involves: C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(tetO-TARDBP*A315T)6Lmit/? Tg(Thy1-tTA)6Lmit/?
Background: involves: C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(tetO-TARDBP*A315T)6Lmit/? Tg(Thy1-tTA)15Lmit/?
Background: involves: C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Amotl2/Amotl2 Tg(Cdh5-cre/ERT2)1Rha/?
Background: involves: C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Amotl1/Amotl1 Tg(Cdh5-cre/ERT2)1Rha/?
Background: involves: C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lamp5/Lamp5
Background: C57BL/6-Lamp5
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Grb2/Grb2
Background: involves: BALB/cJ
Zygosity: hm
Has Mutant Allele: true
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Publication
14987736 | J:88457
First Author: Lafaille JJ
Year: 2004
Journal: J Autoimmun
Title: T-cell receptor transgenic mice in the study of autoimmune diseases.
Volume: 22
Issue: 2
Pages: 95-106
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Publication
20200274 | J:160078
First Author: Jellusova J
Year: 2010
Journal: J Immunol
Title: CD22 x Siglec-G double-deficient mice have massively increased B1 cell numbers and develop systemic autoimmunity.
Volume: 184
Issue: 7
Pages: 3618-27
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Publication
24600033 | J:210020
First Author: Bökers S
Year: 2014
Journal: J Immunol
Title: Siglec-G deficiency leads to more severe collagen-induced arthritis and earlier onset of lupus-like symptoms in MRL/lpr mice.
Volume: 192
Issue: 7
Pages: 2994-3002
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Publication
32069316 | J:285329
First Author: Welsh RA
Year: 2020
Journal: PLoS Biol
Title: Lack of the MHC class II chaperone H2-O causes susceptibility to autoimmune diseases.
Volume: 18
Issue: 2
Pages: e3000590
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Publication
28842668 | J:256562
First Author: Hildebrand S
Year: 2017
Journal: Sci Rep
Title: The E-cadherin/AmotL2 complex organizes actin filaments required for epithelial hexagonal packing and blastocyst hatching.
Volume: 7
Issue: 1
Pages: 9540
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Genotype
Genotype
Symbol: Rag2/Rag2 Tg(HLA-DR2)#Lfug/? Tg(TCROb.1A12)#Lfug/?
Background: involves: C57BL/6 * DBA/2
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd83/Cd83 Marchf8/Marchf8
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd83/Cd83 Marchf1/Marchf1
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd83/Cd83 H2-Ab1/H2-Ab1
Background: involves: 129S4/SvJae * C57BL/6 * C57BL/6N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Amotl2/Amotl2<+> Tg(Cdh5-cre/ERT2)1Rha/?
Background: involves: C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Amotl1/Amotl1 Tg(Cdh5-cre/ERT2)1Rha/? Tg(MMTV-PyVT)634Mul/?
Background: involves: C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lamp5/Lamp5<+>
Background: C57BL/6-Lamp5
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lamp5/Lamp5 Tg(Thy1-MAPT*P301S)58.2Npa/?
Background: involves: C57BL/6 * BALB/c
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lamp5/Lamp5 Tg(Thy1-APP)3Somm/?
Background: involves: C57BL/6 * C57BL/6J * DBA/2
Zygosity: cx
Has Mutant Allele: true
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Publication
24790146 | J:265415
First Author: Hutzler S
Year: 2014
Journal: J Immunol
Title: The ligand-binding domain of Siglec-G is crucial for its selective inhibitory function on B1 cells.
Volume: 192
Issue: 11
Pages: 5406-14
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Publication
36969253 | J:345011
 
First Author: Korn MA
Year: 2023
Journal: Front Immunol
Title: Epistatic effects of Siglec-G and DNase1 or DNase1l3 deficiencies in the development of systemic lupus erythematosus.
Volume: 14
Pages: 1095830
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Publication
32737150 | J:300406
First Author: Inaba A
Year: 2020
Journal: J Immunol
Title: B Lymphocyte-Derived CCL7 Augments Neutrophil and Monocyte Recruitment, Exacerbating Acute Kidney Injury.
Volume: 205
Issue: 5
Pages: 1376-1384
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Publication
14764672 | J:87989
First Author: Benlagha K
Year: 2004
Journal: J Immunol
Title: Mechanisms governing B cell developmental defects in invariant chain-deficient mice.
Volume: 172
Issue: 4
Pages: 2076-83
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Publication
12884868 | J:131508
First Author: Alfonso C
Year: 2003
Journal: Eur J Immunol
Title: H2-O influence on antigen presentation in H2-E-expressing mice.
Volume: 33
Issue: 7
Pages: 2014-21
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Publication
12928379 | J:120210
First Author: Alfonso C
Year: 2003
Journal: J Immunol
Title: Analysis of H2-O influence on antigen presentation by B cells.
Volume: 171
Issue: 5
Pages: 2331-7
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Publication
15265882 | J:92021
First Author: Fallas JL
Year: 2004
Journal: J Immunol
Title: Ectopic expression of HLA-DO in mouse dendritic cells diminishes MHC class II antigen presentation.
Volume: 173
Issue: 3
Pages: 1549-60
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Publication
23836650 | J:198790
First Author: Müller J
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: CD22 ligand-binding and signaling domains reciprocally regulate B-cell Ca2+ signaling.
Volume: 110
Issue: 30
Pages: 12402-7
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Publication
24806444 | J:226656
 
First Author: Hultin S
Year: 2014
Journal: Nat Commun
Title: AmotL2 links VE-cadherin to contractile actin fibres necessary for aortic lumen expansion.
Volume: 5
Pages: 3743
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Publication
20807742 | J:164357
First Author: Draghi NA
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: H2-O, a MHC class II-like protein, sets a threshold for B-cell entry into germinal centers.
Volume: 107
Issue: 38
Pages: 16607-12
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Publication
26407640 | J:228526
First Author: Marks M
Year: 2016
Journal: Gene
Title: Analysis of the Fam181 gene family during mouse development reveals distinct strain-specific expression patterns, suggesting a role in nervous system development and function.
Volume: 575
Issue: 2 Pt 2
Pages: 438-451
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Genotype
Genotype
Symbol: Grb2/Grb2 Cd79a/Cd79a<+>
Background: involves: BALB/c * BALB/cJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Igh/Igh Siglecg/Siglecg
Background: involves: 129 * 129S4/SvJae * BALB/c * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lamp5/Lamp5<+> Tg(Thy1-APP)3Somm/?
Background: involves: C57BL/6 * C57BL/6J * DBA/2
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fam181b/Fam181b<+>
Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6N
Zygosity: ht
Has Mutant Allele: true
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Publication
27503071 | J:236611
First Author: von Rohrscheidt J
Year: 2016
Journal: J Exp Med
Title: Thymic CD4 T cell selection requires attenuation of March8-mediated MHCII turnover in cortical epithelial cells through CD83.
Volume: 213
Issue: 9
Pages: 1685-94
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Publication
30143587 | J:265222
First Author: Özgör L
Year: 2018
Journal: J Immunol
Title: Sialic Acid Ligand Binding of CD22 and Siglec-G Determines Distinct B Cell Functions but Is Dispensable for B Cell Tolerance Induction.
Volume: 201
Issue: 7
Pages: 2107-2116
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Publication
24265393 | J:223622
First Author: Dütting S
Year: 2014
Journal: Circ Res
Title: Growth factor receptor-bound protein 2 contributes to (hem)immunoreceptor tyrosine-based activation motif-mediated signaling in platelets.
Volume: 114
Issue: 3
Pages: 444-453
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Publication
32341059 | J:294651
First Author: Meyer SJ
Year: 2020
Journal: J Immunol
Title: Cullin 3 Is Crucial for Pro-B Cell Proliferation, Interacts with CD22, and Controls CD22 Internalization on B Cells.
Volume: 204
Issue: 12
Pages: 3360-3374
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Publication
30183074 | J:267461
First Author: Willebrand R
Year: 2018
Journal: Eur J Immunol
Title: Murine eosinophil development and allergic lung eosinophilia are largely dependent on the signaling adaptor GRB2.
Volume: 48
Issue: 11
Pages: 1786-1795
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Publication
27464479 | J:253854
 
First Author: Zheng Y
Year: 2016
Journal: Sci Rep
Title: Angiomotin like-1 is a novel component of the N-cadherin complex affecting endothelial/pericyte interaction in normal and tumor angiogenesis.
Volume: 6
Pages: 30622
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Publication
16754718 | J:124421
First Author: Ippolito GC
Year: 2006
Journal: J Exp Med
Title: Forced usage of positively charged amino acids in immunoglobulin CDR-H3 impairs B cell development and antibody production.
Volume: 203
Issue: 6
Pages: 1567-78
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Publication
21427701 | J:171222
First Author: Ackermann JA
Year: 2011
Journal: EMBO J
Title: Grb2 regulates B-cell maturation, B-cell memory responses and inhibits B-cell Ca2+ signalling.
Volume: 30
Issue: 8
Pages: 1621-33
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Genotype
Genotype
Symbol: Amotl1/Amotl1 Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Cdh5-cre/ERT2)1Rha/?
Background: involves: 129X1/SvJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Publication
35288656 | J:332538
First Author: Passarelli MC
Year: 2022
Journal: Nat Cell Biol
Title: Leucyl-tRNA synthetase is a tumour suppressor in breast cancer and regulates codon-dependent translation dynamics.
Volume: 24
Issue: 3
Pages: 307-315
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Publication
35659337 | J:326207
First Author: Wang Z
Year: 2022
Journal: Immunity
Title: Leucine-tRNA-synthase-2-expressing B cells contribute to colorectal cancer immunoevasion.
Volume: 55
Issue: 6
Pages: 1067-1081.e8
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Publication
21623346 | J:174233
First Author: Brenner S
Year: 2011
Journal: EMBO J
Title: A hypomorphic IgH-chain allele affects development of B-cell subsets and favours receptor editing.
Volume: 30
Issue: 13
Pages: 2705-18
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Publication
19844803 | J:163583
First Author: Vasudevan K
Year: 2010
Journal: Transgenic Res
Title: Fertility comparison between wild type and transgenic mice by in vitro fertilization.
Volume: 19
Issue: 4
Pages: 587-94
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Publication
35780436 | J:345459
First Author: Deng Y
Year: 2022
Journal: Acta Neuropathol
Title: Loss of LAMP5 interneurons drives neuronal network dysfunction in Alzheimer's disease.
Volume: 144
Issue: 4
Pages: 637-650
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Publication
34879220 | J:336907
First Author: Newman R
Year: 2021
Journal: Immunity
Title: Chronic calcium signaling in IgE(+) B cells limits plasma cell differentiation and survival.
Volume: 54
Issue: 12
Pages: 2756-2771.e10
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Publication
34135064 | J:320467
First Author: Cullum E
Year: 2021
Journal: J Immunol
Title: MHC Class II Presentation Is Affected by Polymorphism in the H2-Ob Gene and Additional Loci.
Volume: 207
Issue: 1
Pages: 5-14
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Publication
29360039 | J:273460
   
First Author: Collins TN
Year: 2018
Journal: Elife
Title: Crk proteins transduce FGF signaling to promote lens fiber cell elongation.
Volume: 7
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:101977
     
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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