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Search results 1 to 100 out of 163 for Hk2

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Category: Publication
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Type Details Score
Publication
22334075 | J:205641
 
First Author: Panasyuk G
Year: 2012
Journal: Nat Commun
Title: PPARγ contributes to PKM2 and HK2 expression in fatty liver.
Volume: 3
Pages: 672
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Publication
37626853 | J:339993
 
First Author: Weh E
Year: 2023
Journal: Cells
Title: Metabolic Alterations Caused by Simultaneous Loss of HK2 and PKM2 Leads to Photoreceptor Dysfunction and Degeneration.
Volume: 12
Issue: 16
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Publication
37463576 | J:341066
First Author: Rho H
Year: 2023
Journal: Cell Metab
Title: Hexokinase 2-mediated gene expression via histone lactylation is required for hepatic stellate cell activation and liver fibrosis.
Volume: 35
Issue: 8
Pages: 1406-1423.e8
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Publication
34847376 | J:325191
First Author: Hinrichsen F
Year: 2021
Journal: Cell Metab
Title: Microbial regulation of hexokinase 2 links mitochondrial metabolism and cell death in colitis.
Volume: 33
Issue: 12
Pages: 2355-2366.e8
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Publication
24280485 | J:210113
First Author: Gershon TR
Year: 2013
Journal: Cancer Metab
Title: Hexokinase-2-mediated aerobic glycolysis is integral to cerebellar neurogenesis and pathogenesis of medulloblastoma.
Volume: 1
Issue: 1
Pages: 2
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Publication
33082308 | J:308562
First Author: Zhang R
Year: 2020
Journal: Cell Death Dis
Title: Selective knockdown of hexokinase 2 in rods leads to age-related photoreceptor degeneration and retinal metabolic remodeling.
Volume: 11
Issue: 10
Pages: 885
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Publication
29352298 | J:274259
First Author: Varanasi SK
Year: 2018
Journal: PLoS One
Title: Hexokinase II may be dispensable for CD4 T cell responses against a virus infection.
Volume: 13
Issue: 1
Pages: e0191533
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Publication
24190878 | J:282122
First Author: McCommis KS
Year: 2013
Journal: J Am Heart Assoc
Title: Cardiac-specific hexokinase 2 overexpression attenuates hypertrophy by increasing pentose phosphate pathway flux.
Volume: 2
Issue: 6
Pages: e000355
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Publication
29114069 | J:251611
First Author: An MX
Year: 2017
Journal: J Cell Biol
Title: BAG3 directly stabilizes Hexokinase 2 mRNA and promotes aerobic glycolysis in pancreatic cancer cells.
Volume: 216
Issue: 12
Pages: 4091-4105
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Publication
37443289 | J:341079
First Author: Zhang L
Year: 2023
Journal: Nat Cell Biol
Title: STING is a cell-intrinsic metabolic checkpoint restricting aerobic glycolysis by targeting HK2.
Volume: 25
Issue: 8
Pages: 1208-1222
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Publication
23911236 | J:202526
First Author: Patra KC
Year: 2013
Journal: Cancer Cell
Title: Hexokinase 2 is required for tumor initiation and maintenance and its systemic deletion is therapeutic in mouse models of cancer.
Volume: 24
Issue: 2
Pages: 213-228
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Publication
32499533 | J:330747
First Author: Weh E
Year: 2020
Journal: Cell Death Dis
Title: Hexokinase 2 is dispensable for photoreceptor development but is required for survival during aging and outer retinal stress.
Volume: 11
Issue: 6
Pages: 422
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Publication
25176644 | J:314624
First Author: Wang L
Year: 2014
Journal: Cell Rep
Title: Hexokinase 2-mediated Warburg effect is required for PTEN- and p53-deficiency-driven prostate cancer growth.
Volume: 8
Issue: 5
Pages: 1461-74
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Publication
25172909 | J:222201
First Author: Yao M
Year: 2014
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Dicer mediating the expression of miR-143 and miR-155 regulates hexokinase II associated cellular response to hypoxia.
Volume: 307
Issue: 11
Pages: L829-37
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Publication
33398181 | J:305264
First Author: Gu M
Year: 2021
Journal: Nat Immunol
Title: NF-κB-inducing kinase maintains T cell metabolic fitness in antitumor immunity.
Volume: 22
Issue: 2
Pages: 193-204
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Publication
29847794 | J:270849
First Author: Petit L
Year: 2018
Journal: Cell Rep
Title: Aerobic Glycolysis Is Essential for Normal Rod Function and Controls Secondary Cone Death in Retinitis Pigmentosa.
Volume: 23
Issue: 9
Pages: 2629-2642
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Publication
16327801 | J:104468
First Author: Nakagawa Y
Year: 2006
Journal: Nat Med
Title: TFE3 transcriptionally activates hepatic IRS-2, participates in insulin signaling and ameliorates diabetes.
Volume: 12
Issue: 1
Pages: 107-13
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37497007 | J:338575
First Author: Zhuang W
Year: 2023
Journal: Int J Biol Sci
Title: Purinergic receptor P2Y12 boosts autoimmune hepatitis through hexokinase 2-dependent glycolysis in T cells.
Volume: 19
Issue: 11
Pages: 3576-3594
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28467822 | J:252530
First Author: Yu P
Year: 2017
Journal: Nature
Title: FGF-dependent metabolic control of vascular development.
Volume: 545
Issue: 7653
Pages: 224-228
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Publication
37301463 | J:337927
 
First Author: Kawakami H
Year: 2023
Journal: Dev Biol
Title: Sall4 restricts glycolytic metabolism in limb buds through transcriptional regulation of glycolytic enzyme genes.
Volume: 501
Pages: 28-38
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Publication
10656921 | J:59905
First Author: Heikkinen S
Year: 2000
Journal: Mamm Genome
Title: Mouse hexokinase II gene: structure, cDNA, promoter analysis, and expression pattern.
Volume: 11
Issue: 2
Pages: 91-6
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10428828 | J:56644
First Author: Heikkinen S
Year: 1999
Journal: J Biol Chem
Title: Hexokinase II-deficient mice. Prenatal death of homozygotes without disturbances in glucose tolerance in heterozygotes.
Volume: 274
Issue: 32
Pages: 22517-23
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Publication
21071708 | J:183512
First Author: Wu R
Year: 2011
Journal: Circ Res
Title: Reduction in hexokinase II levels results in decreased cardiac function and altered remodeling after ischemia/reperfusion injury.
Volume: 108
Issue: 1
Pages: 60-9
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Publication
22517678 | J:219066
First Author: Wu R
Year: 2012
Journal: EMBO Mol Med
Title: Hexokinase II knockdown results in exaggerated cardiac hypertrophy via increased ROS production.
Volume: 4
Issue: 7
Pages: 633-46
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Publication
12865258 | J:86559
First Author: Fueger PT
Year: 2003
Journal: Am J Physiol Endocrinol Metab
Title: Hexokinase II partial knockout impairs exercise-stimulated glucose uptake in oxidative muscles of mice.
Volume: 285
Issue: 5
Pages: E958-63
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Publication
17639019 | J:126561
First Author: Fueger PT
Year: 2007
Journal: Diabetes
Title: Phosphorylation barriers to skeletal and cardiac muscle glucose uptakes in high-fat fed mice: studies in mice with a 50% reduction of hexokinase II.
Volume: 56
Issue: 10
Pages: 2476-84
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21527739 | J:185690
First Author: Smeele KM
Year: 2011
Journal: Circ Res
Title: Disruption of hexokinase II-mitochondrial binding blocks ischemic preconditioning and causes rapid cardiac necrosis.
Volume: 108
Issue: 10
Pages: 1165-9
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Publication
15878951 | J:112493
First Author: Fueger PT
Year: 2005
Journal: J Physiol
Title: Hexokinase II protein content is a determinant of exercise endurance capacity in the mouse.
Volume: 566
Issue: Pt 2
Pages: 533-41
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8663067 | J:34217
First Author: Tsao TS
Year: 1996
Journal: J Biol Chem
Title: Regulation of hexokinase II gene expression by glucose flux in skeletal muscle.
Volume: 271
Issue: 25
Pages: 14959-63
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22723631 | J:315211
First Author: Smeele KM
Year: 2012
Journal: J Appl Physiol (1985)
Title: Reduced hexokinase II impairs muscle function 2 wk after ischemia-reperfusion through increased cell necrosis and fibrosis.
Volume: 113
Issue: 4
Pages: 608-18
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Publication
25948682 | J:246866
First Author: Lantier L
Year: 2015
Journal: Diabetes
Title: SIRT3 Is Crucial for Maintaining Skeletal Muscle Insulin Action and Protects Against Severe Insulin Resistance in High-Fat-Fed Mice.
Volume: 64
Issue: 9
Pages: 3081-92
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Publication
22233811 | J:181946
First Author: Mergenthaler P
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Mitochondrial hexokinase II (HKII) and phosphoprotein enriched in astrocytes (PEA15) form a molecular switch governing cellular fate depending on the metabolic state.
Volume: 109
Issue: 5
Pages: 1518-23
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Publication
21554247 | J:174799
First Author: Mailloux RJ
Year: 2011
Journal: Biochem J
Title: Hexokinase II acts through UCP3 to suppress mitochondrial reactive oxygen species production and maintain aerobic respiration.
Volume: 437
Issue: 2
Pages: 301-11
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Publication
24990892 | J:213639
First Author: Smith JA
Year: 2014
Journal: Am J Physiol Renal Physiol
Title: Renal cortical hexokinase and pentose phosphate pathway activation through the EGFR/Akt signaling pathway in endotoxin-induced acute kidney injury.
Volume: 307
Issue: 4
Pages: F435-44
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Publication
28986541 | J:255515
First Author: Nederlof R
Year: 2017
Journal: Sci Rep
Title: Cyclophilin D ablation is associated with increased end-ischemic mitochondrial hexokinase activity.
Volume: 7
Issue: 1
Pages: 12749
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Publication
25904018 | J:222689
 
First Author: Lundgaard I
Year: 2015
Journal: Nat Commun
Title: Direct neuronal glucose uptake heralds activity-dependent increases in cerebral metabolism.
Volume: 6
Pages: 6807
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36577999 | J:332635
First Author: Chen C
Year: 2022
Journal: J Neuroinflammation
Title: Directly targeting ASC by lonidamine alleviates inflammasome-driven diseases.
Volume: 19
Issue: 1
Pages: 315
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Publication
18350175 | J:133172
First Author: Chiara F
Year: 2008
Journal: PLoS One
Title: Hexokinase II detachment from mitochondria triggers apoptosis through the permeability transition pore independent of voltage-dependent anion channels.
Volume: 3
Issue: 3
Pages: e1852
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Publication
28285833 | J:258996
First Author: Tan H
Year: 2017
Journal: Immunity
Title: Integrative Proteomics and Phosphoproteomics Profiling Reveals Dynamic Signaling Networks and Bioenergetics Pathways Underlying T Cell Activation.
Volume: 46
Issue: 3
Pages: 488-503
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Publication
28288978 | J:255071
 
First Author: Zhou H
Year: 2017
Journal: J Am Heart Assoc
Title: Mff-Dependent Mitochondrial Fission Contributes to the Pathogenesis of Cardiac Microvasculature Ischemia/Reperfusion Injury via Induction of mROS-Mediated Cardiolipin Oxidation and HK2/VDAC1 Disassociation-Involved mPTP Opening.
Volume: 6
Issue: 3
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28398674 | J:317648
 
First Author: Zhou H
Year: 2017
Journal: J Pineal Res
Title: Melatonin protects cardiac microvasculature against ischemia/reperfusion injury via suppression of mitochondrial fission-VDAC1-HK2-mPTP-mitophagy axis.
Volume: 63
Issue: 1
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21430642 | J:186869
First Author: Gall JM
Year: 2011
Journal: Kidney Int
Title: Hexokinase regulates Bax-mediated mitochondrial membrane injury following ischemic stress.
Volume: 79
Issue: 11
Pages: 1207-16
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36787364 | J:340855
First Author: Fairley LH
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Mitochondrial control of microglial phagocytosis by the translocator protein and hexokinase 2 in Alzheimer's disease.
Volume: 120
Issue: 8
Pages: e2209177120
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Publication
32694609 | J:294996
First Author: Méndez-Lucas A
Year: 2020
Journal: Nat Metab
Title: Identifying strategies to target the metabolic flexibility of tumours.
Volume: 2
Issue: 4
Pages: 335-350
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33835598 | J:316895
First Author: Shen W
Year: 2021
Journal: Glia
Title: Effect of selectively knocking down key metabolic genes in Müller glia on photoreceptor health.
Volume: 69
Issue: 8
Pages: 1966-1986
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Publication
24462113 | J:210540
First Author: Roberts DJ
Year: 2014
Journal: Mol Cell
Title: Hexokinase-II positively regulates glucose starvation-induced autophagy through TORC1 inhibition.
Volume: 53
Issue: 4
Pages: 521-33
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32152094 | J:286586
First Author: Vyssokikh MY
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Mild depolarization of the inner mitochondrial membrane is a crucial component of an anti-aging program.
Volume: 117
Issue: 12
Pages: 6491-6501
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10460589 | J:56735
First Author: Hotfilder M
Year: 1999
Journal: Br J Haematol
Title: Def-2, -3, -6 and -8, novel mouse genes differentially expressed in the haemopoietic system.
Volume: 106
Issue: 2
Pages: 335-44
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9806835 | J:50420
First Author: Weber JS
Year: 1998
Journal: Genomics
Title: High-resolution genetic, physical, and transcript map of the mnd2 region of mouse chromosome 6.
Volume: 54
Issue: 1
Pages: 107-15
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33106477 | J:314146
First Author: Gao W
Year: 2020
Journal: Cell Death Dis
Title: Targeting SKA3 suppresses the proliferation and chemoresistance of laryngeal squamous cell carcinoma via impairing PLK1-AKT axis-mediated glycolysis.
Volume: 11
Issue: 10
Pages: 919
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34857752 | J:321703
First Author: Stojanović O
Year: 2021
Journal: Nat Commun
Title: Dietary excess regulates absorption and surface of gut epithelium through intestinal PPARα.
Volume: 12
Issue: 1
Pages: 7031
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18165236 | J:132397
First Author: Cifuentes D
Year: 2008
Journal: J Biol Chem
Title: Hepatic glycogen synthesis in the absence of glucokinase: the case of embryonic liver.
Volume: 283
Issue: 9
Pages: 5642-9
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21074528 | J:168606
First Author: Leite TC
Year: 2011
Journal: FEBS Lett
Title: Lactate downregulates the glycolytic enzymes hexokinase and phosphofructokinase in diverse tissues from mice.
Volume: 585
Issue: 1
Pages: 92-8
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33517883 | J:302181
First Author: Xu Y
Year: 2021
Journal: BMC Dev Biol
Title: Etomoxir regulates the differentiation of male germ cells by specifically reducing H3K27ac level.
Volume: 21
Issue: 1
Pages: 5
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17576813 | J:125010
First Author: Tracy K
Year: 2007
Journal: Mol Cell Biol
Title: BNIP3 is an RB/E2F target gene required for hypoxia-induced autophagy.
Volume: 27
Issue: 17
Pages: 6229-42
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18500982 | J:137606
 
First Author: Cinelli P
Year: 2008
Journal: BMC Dev Biol
Title: Expression profiling in transgenic FVB/N embryonic stem cells overexpressing STAT3.
Volume: 8
Pages: 57
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20926767 | J:166934
First Author: Trollmann R
Year: 2010
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Late-gestational systemic hypoxia leads to a similar early gene response in mouse placenta and developing brain.
Volume: 299
Issue: 6
Pages: R1489-99
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37545422 | J:338888
     
First Author: Martinez-Garza U
Year: 2023
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Proteomics identifies the developmental regulation of HKDC1 in liver of pigs and mice.
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- | J:24000
     
First Author: Mouse Chromosome Committee
Year: 1995
Journal: Personal Communication
Title: Personal Communication to Mouse Chromosome Committee
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19620286 | J:152599
First Author: Bhaskar PT
Year: 2009
Journal: Mol Cell Biol
Title: mTORC1 hyperactivity inhibits serum deprivation-induced apoptosis via increased hexokinase II and GLUT1 expression, sustained Mcl-1 expression, and glycogen synthase kinase 3beta inhibition.
Volume: 29
Issue: 18
Pages: 5136-47
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32913122 | J:299531
First Author: Wei L
Year: 2020
Journal: J Biol Chem
Title: GGPP depletion initiates metaflammation through disequilibrating CYB5R3-dependent eicosanoid metabolism.
Volume: 295
Issue: 47
Pages: 15988-16001
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18628400 | J:137598
First Author: Lai L
Year: 2008
Journal: Genes Dev
Title: Transcriptional coactivators PGC-1alpha and PGC-lbeta control overlapping programs required for perinatal maturation of the heart.
Volume: 22
Issue: 14
Pages: 1948-61
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35726058 | J:335574
First Author: Dong X
Year: 2022
Journal: Nat Neurosci
Title: Metabolic lactate production coordinates vasculature development and progenitor behavior in the developing mouse neocortex.
Volume: 25
Issue: 7
Pages: 865-875
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33665549 | J:306925
First Author: Menendez-Montes I
Year: 2021
Journal: iScience
Title: Activation of amino acid metabolic program in cardiac HIF1-alpha-deficient mice.
Volume: 24
Issue: 2
Pages: 102124
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27133129 | J:235379
First Author: Yavari A
Year: 2016
Journal: Cell Metab
Title: Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function.
Volume: 23
Issue: 5
Pages: 821-36
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32369449 | J:294228
First Author: Kalailingam P
Year: 2020
Journal: J Clin Invest
Title: Deficiency of MFSD7c results in microcephaly-associated vasculopathy in Fowler syndrome.
Volume: 130
Issue: 8
Pages: 4081-4093
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24086110 | J:201804
First Author: Breckenridge RA
Year: 2013
Journal: PLoS Biol
Title: Hypoxic regulation of hand1 controls the fetal-neonatal switch in cardiac metabolism.
Volume: 11
Issue: 9
Pages: e1001666
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38418556 | J:346910
First Author: Ayyangar U
Year: 2024
Journal: EMBO J
Title: Metabolic rewiring of macrophages by epidermal-derived lactate promotes sterile inflammation in the murine skin.
Volume: 43
Issue: 7
Pages: 1113-1134
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23300479 | J:197599
First Author: Pitetti JL
Year: 2013
Journal: PLoS Genet
Title: Insulin and IGF1 receptors are essential for XX and XY gonadal differentiation and adrenal development in mice.
Volume: 9
Issue: 1
Pages: e1003160
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34677125 | J:314167
   
First Author: Lim S
Year: 2021
Journal: Elife
Title: mTORC1-induced retinal progenitor cell overproliferation leads to accelerated mitotic aging and degeneration of descendent Müller glia.
Volume: 10
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20185832 | J:162597
First Author: Hyvärinen J
Year: 2010
Journal: J Biol Chem
Title: Hearts of hypoxia-inducible factor prolyl 4-hydroxylase-2 hypomorphic mice show protection against acute ischemia-reperfusion injury.
Volume: 285
Issue: 18
Pages: 13646-57
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33059001 | J:306153
First Author: Zhu M
Year: 2021
Journal: Biochim Biophys Acta Mol Basis Dis
Title: A long non-coding RNA specifically expressed in early embryos programs the metabolic balance in adult mice.
Volume: 1867
Issue: 1
Pages: 165988
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32798765 | J:296367
 
First Author: Roberts GAG
Year: 2020
Journal: Placenta
Title: Characterising the dynamics of placental glycogen stores in the mouse.
Volume: 99
Pages: 131-140
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35237793 | J:321836
 
First Author: Zhao K
Year: 2022
Journal: Development
Title: LONP1-mediated mitochondrial quality control safeguards metabolic shifts in heart development.
Volume: 149
Issue: 6
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27997827 | J:237617
First Author: Menendez-Montes I
Year: 2016
Journal: Dev Cell
Title: Myocardial VHL-HIF Signaling Controls an Embryonic Metabolic Switch Essential for Cardiac Maturation.
Volume: 39
Issue: 6
Pages: 724-739
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27597886 | J:270627
First Author: Sakakibara I
Year: 2016
Journal: Skelet Muscle
Title: Six1 homeoprotein drives myofiber type IIA specialization in soleus muscle.
Volume: 6
Issue: 1
Pages: 30
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35247391 | J:323229
First Author: Rosendahl AH
Year: 2022
Journal: J Biol Chem
Title: Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia.
Volume: 298
Issue: 4
Pages: 101787
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17626619 | J:125993
 
First Author: Cankaya M
Year: 2007
Journal: BMC Genomics
Title: An analysis of expression patterns of genes encoding proteins with catalytic activities.
Volume: 8
Pages: 232
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16110338 | J:107820
First Author: Corbo JC
Year: 2005
Journal: PLoS Genet
Title: A hybrid photoreceptor expressing both rod and cone genes in a mouse model of enhanced S-cone syndrome.
Volume: 1
Issue: 2
Pages: e11
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26416771 | J:227211
 
First Author: Zhang Y
Year: 2015
Journal: Nat Commun
Title: Maternal bile acid transporter deficiency promotes neonatal demise.
Volume: 6
Pages: 8186
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30228991 | J:283457
 
First Author: Uijtdewilligen PJE
Year: 2018
Journal: Biomed Res Int
Title: Dynamic Expression of Genes Involved in Proteoglycan/Glycosaminoglycan Metabolism during Skin Development.
Volume: 2018
Pages: 9873471
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30728831 | J:304253
 
First Author: Jones MR
Year: 2018
Journal: Front Genet
Title: A Comprehensive Analysis of Fibroblast Growth Factor Receptor 2b Signaling on Epithelial Tip Progenitor Cells During Early Mouse Lung Branching Morphogenesis.
Volume: 9
Pages: 746
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27215380 | J:236179
First Author: Bowman CE
Year: 2016
Journal: Mol Cell Biol
Title: Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series.
Volume: 36
Issue: 15
Pages: 2089-104
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28245920 | J:240028
First Author: Bulusu V
Year: 2017
Journal: Dev Cell
Title: Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development.
Volume: 40
Issue: 4
Pages: 331-341.e4
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Publication
31202927 | J:281175
 
First Author: Yorgan TA
Year: 2019
Journal: Bone
Title: Osteoblast-specific expression of Panx3 is dispensable for postnatal bone remodeling.
Volume: 127
Pages: 155-163
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20439489 | J:163558
First Author: Tarantino C
Year: 2010
Journal: FASEB J
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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