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Search results 101 to 200 out of 544 for Adam17

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Type Details Score
Publication
First Author: Fan D
Year: 2015
Journal: Circ Heart Fail
Title: Cardiomyocyte A Disintegrin And Metalloproteinase 17 (ADAM17) Is Essential in Post-Myocardial Infarction Repair by Regulating Angiogenesis.
Volume: 8
Issue: 5
Pages: 970-9
Publication
First Author: Dreymueller D
Year: 2014
Journal: J Immunol
Title: Smooth muscle cells relay acute pulmonary inflammation via distinct ADAM17/ErbB axes.
Volume: 192
Issue: 2
Pages: 722-31
Publication  
First Author: Shen M
Year: 2017
Journal: J Mol Cell Cardiol
Title: Loss of smooth muscle cell disintegrin and metalloproteinase 17 transiently suppresses angiotensin II-induced hypertension and end-organ damage.
Volume: 103
Pages: 11-21
Publication
First Author: Feng Y
Year: 2015
Journal: Mol Cell Biol
Title: Loss of ADAM17-Mediated Tumor Necrosis Factor Alpha Signaling in Intestinal Cells Attenuates Mucosal Atrophy in a Mouse Model of Parenteral Nutrition.
Volume: 35
Issue: 21
Pages: 3604-21
Publication
First Author: Zunke F
Year: 2017
Journal: Biochim Biophys Acta Mol Cell Res
Title: The shedding protease ADAM17: Physiology and pathophysiology.
Volume: 1864
Issue: 11 Pt B
Pages: 2059-2070
Publication
First Author: Quarta S
Year: 2019
Journal: FASEB J
Title: Impaired mechanical, heat, and cold nociception in a murine model of genetic TACE/ADAM17 knockdown.
Volume: 33
Issue: 3
Pages: 4418-4431
Publication
First Author: Hassemer EL
Year: 2010
Journal: Genetics
Title: The waved with open eyelids (woe) locus is a hypomorphic mouse mutation in Adam17.
Volume: 185
Issue: 1
Pages: 245-55
Publication
First Author: Otulakowski G
Year: 2014
Journal: J Physiol
Title: Hypercapnia attenuates ventilator-induced lung injury via a disintegrin and metalloprotease-17.
Volume: 592
Issue: 20
Pages: 4507-21
Publication  
First Author: Sommer D
Year: 2019
Journal: Brain Behav Immun
Title: ADAM17-deficiency on microglia but not on macrophages promotes phagocytosis and functional recovery after spinal cord injury.
Volume: 80
Pages: 129-145
Publication  
First Author: Romi E
Year: 2014
Journal: Nat Commun
Title: ADAM metalloproteases promote a developmental switch in responsiveness to the axonal repellant Sema3A.
Volume: 5
Pages: 4058
Publication
First Author: Fan D
Year: 2016
Journal: Hypertension
Title: A Disintegrin and Metalloprotease-17 Regulates Pressure Overload-Induced Myocardial Hypertrophy and Dysfunction Through Proteolytic Processing of Integrin β1.
Volume: 68
Issue: 4
Pages: 937-48
Publication
First Author: Ardito CM
Year: 2012
Journal: Cancer Cell
Title: EGF receptor is required for KRAS-induced pancreatic tumorigenesis.
Volume: 22
Issue: 3
Pages: 304-17
Publication    
First Author: Künzel U
Year: 2018
Journal: Elife
Title: FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complex.
Volume: 7
Publication
First Author: Lownik JC
Year: 2019
Journal: Biochem Biophys Res Commun
Title: A Disintegrin and Metalloproteinase 17 is required for ILC2 responses to IL-33.
Volume: 512
Issue: 4
Pages: 723-728
Publication    
First Author: Capone C
Year: 2016
Journal: Elife
Title: Mechanistic insights into a TIMP3-sensitive pathway constitutively engaged in the regulation of cerebral hemodynamics.
Volume: 5
Publication
First Author: Dierker T
Year: 2009
Journal: J Biol Chem
Title: Heparan sulfate-modulated, metalloprotease-mediated sonic hedgehog release from producing cells.
Volume: 284
Issue: 12
Pages: 8013-22
Publication  
First Author: Shimoda M
Year: 2016
Journal: EBioMedicine
Title: Epithelial Cell-Derived a Disintegrin and Metalloproteinase-17 Confers Resistance to Colonic Inflammation Through EGFR Activation.
Volume: 5
Pages: 114-24
Publication
First Author: Sternlicht MD
Year: 2005
Journal: Development
Title: Mammary ductal morphogenesis requires paracrine activation of stromal EGFR via ADAM17-dependent shedding of epithelial amphiregulin.
Volume: 132
Issue: 17
Pages: 3923-33
Publication
First Author: Cerretti DP
Year: 1999
Journal: Cytokine
Title: Characterization of the cDNA and gene for mouse tumour necrosis factor alpha converting enzyme (TACE/ADAM17) and its location to mouse chromosome 12 and human chromosome 2p25.
Volume: 11
Issue: 8
Pages: 541-51
Publication
First Author: Adrain C
Year: 2012
Journal: Science
Title: Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACE.
Volume: 335
Issue: 6065
Pages: 225-8
Publication  
First Author: Shipman WD
Year: 2018
Journal: Sci Transl Med
Title: A protective Langerhans cell-keratinocyte axis that is dysfunctional in photosensitivity.
Volume: 10
Issue: 454
Publication
First Author: Mohammed RN
Year: 2019
Journal: Sci Rep
Title: ADAM17-dependent proteolysis of L-selectin promotes early clonal expansion of cytotoxic T cells.
Volume: 9
Issue: 1
Pages: 5487
Publication
First Author: Fuchslocher Chico J
Year: 2018
Journal: Oncotarget
Title: The enhanced susceptibility of ADAM-17 hypomorphic mice to DSS-induced colitis is not ameliorated by loss of RIPK3, revealing an unexpected function of ADAM-17 in necroptosis.
Volume: 9
Issue: 16
Pages: 12941-12958
Publication
First Author: Zhu L
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Regulated surface expression and shedding support a dual role for semaphorin 4D in platelet responses to vascular injury.
Volume: 104
Issue: 5
Pages: 1621-6
Publication
First Author: Horiuchi K
Year: 2007
Journal: Mol Biol Cell
Title: Substrate selectivity of epidermal growth factor-receptor ligand sheddases and their regulation by phorbol esters and calcium influx.
Volume: 18
Issue: 1
Pages: 176-88
Publication
First Author: Gorovoy M
Year: 2010
Journal: J Leukoc Biol
Title: Inflammatory mediators promote production of shed LRP1/CD91, which regulates cell signaling and cytokine expression by macrophages.
Volume: 88
Issue: 4
Pages: 769-78
Publication
First Author: Gupte M
Year: 2008
Journal: Am J Physiol Regul Integr Comp Physiol
Title: ACE2 is expressed in mouse adipocytes and regulated by a high-fat diet.
Volume: 295
Issue: 3
Pages: R781-8
Publication
First Author: Flynn CM
Year: 2020
Journal: Sci Rep
Title: Cathepsin S provokes interleukin-6 (IL-6) trans-signaling through cleavage of the IL-6 receptor in vitro.
Volume: 10
Issue: 1
Pages: 21612
Publication
First Author: Zang Y
Year: 2022
Journal: Cell Rep
Title: Tace/ADAM17 is a bi-directional regulator of axon guidance that coordinates distinct Frazzled and Dcc receptor signaling outputs.
Volume: 41
Issue: 10
Pages: 111785
Publication
First Author: van Erp S
Year: 2015
Journal: Dev Cell
Title: Lrig2 Negatively Regulates Ectodomain Shedding of Axon Guidance Receptors by ADAM Proteases.
Volume: 35
Issue: 5
Pages: 537-52
Publication
First Author: Marcinkiewicz M
Year: 2000
Journal: J Neurochem
Title: Coordinated expression of beta-amyloid precursor protein and the putative beta-secretase BACE and alpha-secretase ADAM10 in mouse and human brain.
Volume: 75
Issue: 5
Pages: 2133-43
Publication
First Author: Li N
Year: 2007
Journal: EMBO J
Title: Metalloproteases regulate T-cell proliferation and effector function via LAG-3.
Volume: 26
Issue: 2
Pages: 494-504
Publication  
First Author: Fang R
Year: 2020
Journal: Int J Mol Sci
Title: Role of iRhoms 1 and 2 in Endochondral Ossification.
Volume: 21
Issue: 22
Publication
First Author: Chalaris A
Year: 2007
Journal: Blood
Title: Apoptosis is a natural stimulus of IL6R shedding and contributes to the proinflammatory trans-signaling function of neutrophils.
Volume: 110
Issue: 6
Pages: 1748-55
Publication
First Author: Casagrande V
Year: 2017
Journal: Sci Rep
Title: Hepatocyte specific TIMP3 expression prevents diet dependent fatty liver disease and hepatocellular carcinoma.
Volume: 7
Issue: 1
Pages: 6747
Publication
First Author: Qing X
Year: 2016
Journal: Eur J Immunol
Title: iRhom2 regulates CSF1R cell surface expression and non-steady state myelopoiesis in mice.
Volume: 46
Issue: 12
Pages: 2737-2748
Publication
First Author: Bender M
Year: 2010
Journal: Blood
Title: Differentially regulated GPVI ectodomain shedding by multiple platelet-expressed proteinases.
Volume: 116
Issue: 17
Pages: 3347-55
Publication
First Author: Mishra HK
Year: 2015
Journal: J Leukoc Biol
Title: Regulation of CXCR2 expression and function by a disintegrin and metalloprotease-17 (ADAM17).
Volume: 97
Issue: 3
Pages: 447-54
Publication
First Author: Huang J
Year: 2005
Journal: Mol Biol Cell
Title: Selective modulation of integrin-mediated cell migration by distinct ADAM family members.
Volume: 16
Issue: 10
Pages: 4982-91
Publication
First Author: Koenen RR
Year: 2009
Journal: Blood
Title: Regulated release and functional modulation of junctional adhesion molecule A by disintegrin metalloproteinases.
Volume: 113
Issue: 19
Pages: 4799-809
Publication
First Author: Motani K
Year: 2018
Journal: J Biol Chem
Title: Activation of stimulator of interferon genes (STING) induces ADAM17-mediated shedding of the immune semaphorin SEMA4D.
Volume: 293
Issue: 20
Pages: 7717-7726
Publication  
First Author: Amin A
Year: 2023
Journal: Mol Metab
Title: Semaphorin 4B is an ADAM17-cleaved adipokine that inhibits adipocyte differentiation and thermogenesis.
Volume: 73
Pages: 101731
Publication
First Author: Asayesh A
Year: 2005
Journal: Dev Dyn
Title: Developmental expression of metalloproteases ADAM 9, 10, and 17 becomes restricted to divergent pancreatic compartments.
Volume: 232
Issue: 4
Pages: 1105-14
Publication
First Author: McMahan RS
Year: 2013
Journal: Am J Physiol Gastrointest Liver Physiol
Title: A disintegrin and metalloproteinase 17 regulates TNF and TNFR1 levels in inflammation and liver regeneration in mice.
Volume: 305
Issue: 1
Pages: G25-34
Publication
First Author: Lucitti JL
Year: 2012
Journal: Circ Res
Title: Formation of the collateral circulation is regulated by vascular endothelial growth factor-A and a disintegrin and metalloprotease family members 10 and 17.
Volume: 111
Issue: 12
Pages: 1539-50
Publication
First Author: Li X
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: iRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signaling.
Volume: 112
Issue: 19
Pages: 6080-5
Publication
First Author: Wang Y
Year: 2021
Journal: Haematologica
Title: Desialylation of O-glycans on glycoprotein Ibα drives receptor signaling and platelet clearance.
Volume: 106
Issue: 1
Pages: 220-229
Publication
First Author: Horiuchi K
Year: 2005
Journal: Dev Biol
Title: Evaluation of the contributions of ADAMs 9, 12, 15, 17, and 19 to heart development and ectodomain shedding of neuregulins beta1 and beta2.
Volume: 283
Issue: 2
Pages: 459-71
Publication
First Author: Jin Y
Year: 2013
Journal: Mol Cell Biol
Title: Deletion of Cdc42 enhances ADAM17-mediated vascular endothelial growth factor receptor 2 shedding and impairs vascular endothelial cell survival and vasculogenesis.
Volume: 33
Issue: 21
Pages: 4181-97
Publication
First Author: Alabi RO
Year: 2016
Journal: Circ Res
Title: ADAM10-Dependent Signaling Through Notch1 and Notch4 Controls Development of Organ-Specific Vascular Beds.
Volume: 119
Issue: 4
Pages: 519-31
Publication
First Author: Pedersen KB
Year: 2015
Journal: Endocrinology
Title: Dynamics of ADAM17-Mediated Shedding of ACE2 Applied to Pancreatic Islets of Male db/db Mice.
Volume: 156
Issue: 12
Pages: 4411-25
Publication
First Author: Swendeman S
Year: 2008
Journal: Circ Res
Title: VEGF-A stimulates ADAM17-dependent shedding of VEGFR2 and crosstalk between VEGFR2 and ERK signaling.
Volume: 103
Issue: 9
Pages: 916-8
Publication
First Author: Maretzky T
Year: 2005
Journal: Mol Cell Biol
Title: L1 is sequentially processed by two differently activated metalloproteases and presenilin/gamma-secretase and regulates neural cell adhesion, cell migration, and neurite outgrowth.
Volume: 25
Issue: 20
Pages: 9040-53
Publication
First Author: Maretzky T
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: iRhom2 controls the substrate selectivity of stimulated ADAM17-dependent ectodomain shedding.
Volume: 110
Issue: 28
Pages: 11433-8
Publication
First Author: Kefaloyianni E
Year: 2019
Journal: J Am Soc Nephrol
Title: Proximal Tubule-Derived Amphiregulin Amplifies and Integrates Profibrotic EGF Receptor Signals in Kidney Fibrosis.
Volume: 30
Issue: 12
Pages: 2370-2383
Publication
First Author: Anthony SM
Year: 2015
Journal: PLoS One
Title: Soluble interleukin-15 complexes are generated in vivo by type I interferon dependent and independent pathways.
Volume: 10
Issue: 3
Pages: e0120274
Publication  
First Author: Zhai CG
Year: 2018
Journal: J Mol Cell Cardiol
Title: DKK3 overexpression attenuates cardiac hypertrophy and fibrosis in an angiotensin-perfused animal model by regulating the ADAM17/ACE2 and GSK-3β/β-catenin pathways.
Volume: 114
Pages: 243-252
HT Experiment
Series Id: GSE21691
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication
First Author: Hartl D
Year: 2008
Journal: J Biol Chem
Title: Acidic mammalian chitinase is secreted via an ADAM17/epidermal growth factor receptor-dependent pathway and stimulates chemokine production by pulmonary epithelial cells.
Volume: 283
Issue: 48
Pages: 33472-82
Publication
First Author: Murthy A
Year: 2010
Journal: J Clin Invest
Title: Ectodomain shedding of EGFR ligands and TNFR1 dictates hepatocyte apoptosis during fulminant hepatitis in mice.
Volume: 120
Issue: 8
Pages: 2731-44
Publication
First Author: Brandl K
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands.
Volume: 107
Issue: 46
Pages: 19967-72
Publication
First Author: Tüshaus J
Year: 2021
Journal: FASEB J
Title: The pseudoprotease iRhom1 controls ectodomain shedding of membrane proteins in the nervous system.
Volume: 35
Issue: 11
Pages: e21962
Publication
First Author: Franzke CW
Year: 2009
Journal: J Biol Chem
Title: Shedding of collagen XVII/BP180 in skin depends on both ADAM10 and ADAM9.
Volume: 284
Issue: 35
Pages: 23386-96
Publication
First Author: Toonen JA
Year: 2016
Journal: PLoS One
Title: A Disintegrin and Metalloproteinase10 (ADAM10) Regulates NOTCH Signaling during Early Retinal Development.
Volume: 11
Issue: 5
Pages: e0156184
Publication
First Author: Alfa Cissé M
Year: 2008
Journal: Mol Cell Neurosci
Title: Isoform-specific contribution of protein kinase C to prion processing.
Volume: 39
Issue: 3
Pages: 400-10
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Amour A
Year: 1998
Journal: FEBS Lett
Title: TNF-alpha converting enzyme (TACE) is inhibited by TIMP-3.
Volume: 435
Issue: 1
Pages: 39-44
Publication
First Author: Mizui Y
Year: 1999
Journal: Gene
Title: cDNA cloning of mouse tumor necrosis factor-alpha converting enzyme (TACE) and partial analysis of its promoter.
Volume: 233
Issue: 1-2
Pages: 67-74
Publication
First Author: Park JA
Year: 2013
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Human neutrophil elastase-mediated goblet cell metaplasia is attenuated in TACE-deficient mice.
Volume: 304
Issue: 10
Pages: L701-7
Publication
First Author: Tang J
Year: 2011
Journal: Blood
Title: Adam17-dependent shedding limits early neutrophil influx but does not alter early monocyte recruitment to inflammatory sites.
Volume: 118
Issue: 3
Pages: 786-94
Publication
First Author: Kaneko H
Year: 2011
Journal: Circ J
Title: Tumor necrosis factor-α converting enzyme inactivation ameliorates high-fat diet-induced insulin resistance and altered energy homeostasis.
Volume: 75
Issue: 10
Pages: 2482-90
Publication
First Author: Bergmeier W
Year: 2004
Journal: Circ Res
Title: Tumor necrosis factor-alpha-converting enzyme (ADAM17) mediates GPIbalpha shedding from platelets in vitro and in vivo.
Volume: 95
Issue: 7
Pages: 677-83
Publication
First Author: Gelling RW
Year: 2008
Journal: Endocrinology
Title: Deficiency of TNFalpha converting enzyme (TACE/ADAM17) causes a lean, hypermetabolic phenotype in mice.
Volume: 149
Issue: 12
Pages: 6053-64
Publication
First Author: Wang Y
Year: 2013
Journal: J Biol Chem
Title: Strain-induced differentiation of fetal type II epithelial cells is mediated via the integrin α6β1-ADAM17/tumor necrosis factor-α-converting enzyme (TACE) signaling pathway.
Volume: 288
Issue: 35
Pages: 25646-57
Publication
First Author: Buxbaum JD
Year: 1998
Journal: J Biol Chem
Title: Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer amyloid protein precursor.
Volume: 273
Issue: 43
Pages: 27765-7
Publication
First Author: Peschon JJ
Year: 1998
Journal: Science
Title: An essential role for ectodomain shedding in mammalian development.
Volume: 282
Issue: 5392
Pages: 1281-4
Publication
First Author: Serino M
Year: 2007
Journal: Diabetes
Title: Mice heterozygous for tumor necrosis factor-alpha converting enzyme are protected from obesity-induced insulin resistance and diabetes.
Volume: 56
Issue: 10
Pages: 2541-6
Publication
First Author: Yoda M
Year: 2013
Journal: PLoS One
Title: Systemic overexpression of TNFα-converting enzyme does not lead to enhanced shedding activity in vivo.
Volume: 8
Issue: 1
Pages: e54412
Publication
First Author: Soond SM
Year: 2005
Journal: J Cell Sci
Title: ERK-mediated phosphorylation of Thr735 in TNFalpha-converting enzyme and its potential role in TACE protein trafficking.
Volume: 118
Issue: Pt 11
Pages: 2371-80
Publication
First Author: Myers TJ
Year: 2009
Journal: Mol Biol Cell
Title: Mitochondrial reactive oxygen species mediate GPCR-induced TACE/ADAM17-dependent transforming growth factor-alpha shedding.
Volume: 20
Issue: 24
Pages: 5236-49
Publication
First Author: Fukaya S
Year: 2013
Journal: Lab Invest
Title: Overexpression of TNF-α-converting enzyme in fibroblasts augments dermal fibrosis after inflammation.
Volume: 93
Issue: 1
Pages: 72-80
Publication
First Author: Kawasaki S
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Regulation of TNFα converting enzyme activity in visceral adipose tissue of obese mice.
Volume: 430
Issue: 4
Pages: 1189-94