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Search results 401 to 500 out of 545 for Adam17

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Type Details Score
Publication
14673146 | J:87592
First Author: Zhou HM
Year: 2004
Journal: Mol Cell Biol
Title: Essential role for ADAM19 in cardiovascular morphogenesis.
Volume: 24
Issue: 1
Pages: 96-104
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Publication
15574878 | J:97329
First Author: Yang LT
Year: 2005
Journal: Mol Biol Cell
Title: Fringe glycosyltransferases differentially modulate Notch1 proteolysis induced by Delta1 and Jagged1.
Volume: 16
Issue: 2
Pages: 927-42
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Publication
19705113 | J:152405
First Author: Kurey I
Year: 2009
Journal: Immunogenetics
Title: Distinct genetic control of parasite elimination, dissemination, and disease after Leishmania major infection.
Volume: 61
Issue: 9
Pages: 619-33
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Publication
16054021 | J:135488
First Author: Higashiyama S
Year: 2005
Journal: Biochim Biophys Acta
Title: ADAM-mediated ectodomain shedding of HB-EGF in receptor cross-talk.
Volume: 1751
Issue: 1
Pages: 110-7
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Publication
14499647 | J:85547
First Author: Shi W
Year: 2003
Journal: Dev Biol
Title: TACE is required for fetal murine cardiac development and modeling.
Volume: 261
Issue: 2
Pages: 371-80
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Publication
24498290 | J:212851
First Author: Meng Q
Year: 2014
Journal: PLoS One
Title: Expression of signaling components in embryonic eyelid epithelium.
Volume: 9
Issue: 2
Pages: e87038
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Publication
17804806 | J:124878
First Author: Sierro F
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7.
Volume: 104
Issue: 37
Pages: 14759-64
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Publication
15817462 | J:100263
First Author: Kim IM
Year: 2005
Journal: J Biol Chem
Title: The forkhead box m1 transcription factor is essential for embryonic development of pulmonary vasculature.
Volume: 280
Issue: 23
Pages: 22278-86
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Publication
21205794 | J:170542
First Author: Weber S
Year: 2011
Journal: Development
Title: The disintegrin/metalloproteinase Adam10 is essential for epidermal integrity and Notch-mediated signaling.
Volume: 138
Issue: 3
Pages: 495-505
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Publication
34767447 | J:315981
First Author: Torregrosa-CarriĆ³n R
Year: 2021
Journal: Sci Adv
Title: Adhesion G protein-coupled receptor Gpr126/Adgrg6 is essential for placental development.
Volume: 7
Issue: 46
Pages: eabj5445
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Publication
25546423 | J:228844
First Author: Leilei Y
Year: 2014
Journal: PLoS One
Title: iRhom2 mutation leads to aberrant hair follicle differentiation in mice.
Volume: 9
Issue: 12
Pages: e115114
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Publication
24652767 | J:213427
First Author: Adissu HA
Year: 2014
Journal: Dis Model Mech
Title: Histopathology reveals correlative and unique phenotypes in a high-throughput mouse phenotyping screen.
Volume: 7
Issue: 5
Pages: 515-24
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Publication
16332269 | J:156373
First Author: Chang B
Year: 2005
Journal: Vis Neurosci
Title: Mouse models of ocular diseases.
Volume: 22
Issue: 5
Pages: 587-93
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Publication
25572963 | J:224431
 
First Author: Besschetnova TY
Year: 2015
Journal: Matrix Biol
Title: Regulatory mechanisms of anthrax toxin receptor 1-dependent vascular and connective tissue homeostasis.
Volume: 42
Pages: 56-73
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Publication
35247391 | J:323229
First Author: Rosendahl AH
Year: 2022
Journal: J Biol Chem
Title: Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia.
Volume: 298
Issue: 4
Pages: 101787
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Publication
21421844 | J:171226
First Author: Cullen M
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood-brain barrier.
Volume: 108
Issue: 14
Pages: 5759-64
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
29688375 | J:250512
   
First Author: Li J
Year: 2018
Journal: Database (Oxford)
Title: CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice.
Volume: 2018
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Publication
- | J:165965
     
First Author: Mouse Genome Informatics and the Europhenome Mouse Phenotyping Resource
Year: 2010
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from Europhenome
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Publication
24006456 | J:221550
First Author: Abonnenc M
Year: 2013
Journal: Circ Res
Title: Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Volume: 113
Issue: 10
Pages: 1138-47
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Publication
- | J:175295
     
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
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Publication
30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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UniProt Feature
UniProt Feature
Begin: 1710
Description: Cleavage; by ADAM17
Type: site
End: 1711
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UniProt Feature
UniProt Feature
Begin: 588
Description: Cleavage; by ADAM17
Type: site
End: 589
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UniProt Feature
UniProt Feature
Begin: 79
Description: Cleavage; by ADAM17
Type: site
End: 80
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HT Experiment
E-GEOD-38830 | Conditional keratinocyte-specific ADAM17 knockout in mice alters skin homeostasis
Series Id: GSE38830
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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UniProt Feature
UniProt Feature
Begin: 354
Description: Cleavage; by ADAM10 and ADAM17
Type: site
End: 355
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Publication
17010968 | J:143672
First Author: Tellier E
Year: 2006
Journal: Exp Cell Res
Title: The shedding activity of ADAM17 is sequestered in lipid rafts.
Volume: 312
Issue: 20
Pages: 3969-80
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Publication
29361535 | J:258334
 
First Author: Li R
Year: 2018
Journal: J Cell Sci
Title: Regulation of profibrotic responses by ADAM17 activation in high glucose requires its C-terminus and FAK.
Volume: 131
Issue: 4
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Publication
31006330 | J:287903
First Author: Xu J
Year: 2019
Journal: Hypertension
Title: Activation of ADAM17 (A Disintegrin and Metalloprotease 17) on Glutamatergic Neurons Selectively Promotes Sympathoexcitation.
Volume: 73
Issue: 6
Pages: 1266-1274
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Publication
24452639 | J:207415
First Author: Salem ES
Year: 2014
Journal: Am J Physiol Renal Physiol
Title: Insulin treatment attenuates renal ADAM17 and ACE2 shedding in diabetic Akita mice.
Volume: 306
Issue: 6
Pages: F629-39
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Publication
26697977 | J:281970
First Author: Riera M
Year: 2016
Journal: Am J Physiol Renal Physiol
Title: Paricalcitol modulates ACE2 shedding and renal ADAM17 in NOD mice beyond proteinuria.
Volume: 310
Issue: 6
Pages: F534-46
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Publication
- | J:304620
     
First Author: Lartey NL
Year: 2021
Journal: bioRxiv
Title: ADAM17 inhibition prevents neutrophilia and lung injury in a mouse model of Covid-19.
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Publication
36937050 | J:345219
 
First Author: Tian Y
Year: 2023
Journal: Front Mol Neurosci
Title: The role of ADAM17 in cerebrovascular and cognitive function in the APP/PS1 mouse model of Alzheimer's disease.
Volume: 16
Pages: 1125932
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GO Term
GO:0140910 | iRhom2/ADAM17 sheddase complex
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Publication
24227843 | J:207757
First Author: Heurich A
Year: 2014
Journal: J Virol
Title: TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike protein.
Volume: 88
Issue: 2
Pages: 1293-307
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GXD Expression
GXD Expression
Probe: MGI:6690292
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6690294
Age: embryonic day 15.5
Image: 4C
Note: Expression was detected in neurons in the substantia nigra and the ventral tegmental area and co-localized with Adam17 immunostaining.
Specimen Label: 4C
Detected: true
Specimen Num: 2
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Allele
Adam17<em1Smoc> | MGI:7288105
Name: a disintegrin and metallopeptidase domain 17; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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GXD Expression
GXD Expression
Probe: MGI:3580797
Assay Type: Immunohistochemistry
Annotation Date: 2005-07-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750328
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3580832
Age: postnatal adult
Image: 5H, 5I
Note: Expression was detected in the cell membrane. Expression did not colocalize with Adam17 in the cell membranes of the islets of Langerhans.
Specimen Label: 5H, 5I
Detected: true
Specimen Num: 3
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Publication
23521534 | -
First Author: DĆ¼sterhƶft S
Year: 2013
Journal: J Am Chem Soc
Title: Membrane-proximal domain of a disintegrin and metalloprotease-17 represents the putative molecular switch of its shedding activity operated by protein-disulfide isomerase.
Volume: 135
Issue: 15
Pages: 5776-81
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Protein Domain
IPR032029 | ADAM17_MPD
Type: Domain
Description: This entry represents the membrane-proximal domain (MPD) of disintegrin and metalloproteinase domain-containing protein 17 (ADAM17) from animals. ADAM17 is a major sheddase responsible for the regulation of a wide range of biological processes, such as cellular differentiation, regeneration, and cancer progression. This MPD region acts as the sheddase switch. PDI (protein-disulfide isomerase) interacts with ADAM17 and down-regulates its enzymatic activity. The interaction is directly with the MPD, the region of dimerisation and substrate recognition, where it catalyses an isomerisation of disulfide bridges within the thioredoxin motif CXXC. This isomerisation results in a major structural change between an active, open state and an inactive, closed state of the MPD. This change is thought to act as a molecular switch, allowing a global reorientation of the extracellular domains in ADAM17 and regulating its shedding activity [].
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Publication
10415747 | -
 
First Author: Killar L
Year: 1999
Journal: Ann N Y Acad Sci
Title: Adamalysins. A family of metzincins including TNF-alpha converting enzyme (TACE).
Volume: 878
Pages: 442-52
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Protein Domain
IPR034025 | ADAM10_ADAM17
Type: Domain
Description: This entry includes proteins with reprolysin-like metallopeptidase domains and includes ADAM10 (also known as myelin-associated metalloendopeptidase, MEROPS identifier M12.210), ADAM17 (also known as tumour necrosis factor alpha-convertase, MEROPS identifier M12.217), kuzbanian (MEROPS identifiers M12.211 and M12.322) and ADM-4 (MEROPS identifier M12.329) [].
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Publication
34672089 | J:322407
First Author: Sun H
Year: 2021
Journal: Genes Brain Behav
Title: iRhom1 rescues cognitive dysfunction in multiple sclerosis via preventing myelin injury.
Volume: 20
Issue: 8
Pages: e12771
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Publication
27941799 | J:243234
 
First Author: Revandkar A
Year: 2016
Journal: Nat Commun
Title: Inhibition of Notch pathway arrests PTEN-deficient advanced prostate cancer by triggering p27-driven cellular senescence.
Volume: 7
Pages: 13719
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Publication
26108729 | J:223005
 
First Author: Dombernowsky SL
Year: 2015
Journal: Nat Commun
Title: The sorting protein PACS-2 promotes ErbB signalling by regulating recycling of the metalloproteinase ADAM17.
Volume: 6
Pages: 7518
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Publication
29321225 | J:259750
First Author: Song WM
Year: 2018
Journal: J Exp Med
Title: Humanized TREM2 mice reveal microglia-intrinsic and -extrinsic effects of R47H polymorphism.
Volume: 215
Issue: 3
Pages: 745-760
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Publication
35757773 | J:334874
 
First Author: Hedges JF
Year: 2022
Journal: Front Immunol
Title: An ADAM17-Neutralizing Antibody Reduces Inflammation and Mortality While Increasing Viral Burden in a COVID-19 Mouse Model.
Volume: 13
Pages: 918881
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Publication
28084316 | J:244044
 
First Author: Hurst LA
Year: 2017
Journal: Nat Commun
Title: TNFĪ± drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling.
Volume: 8
Pages: 14079
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Publication
32400009 | J:293902
First Author: Kruse T
Year: 2020
Journal: EMBO J
Title: Mechanisms of site-specific dephosphorylation and kinase opposition imposed by PP2A regulatory subunits.
Volume: 39
Issue: 13
Pages: e103695
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Protein
Q9Z0F8
Organism: Mus musculus/domesticus
Length: 827  
Fragment?: false
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Protein
E9PXU2
Organism: Mus musculus/domesticus
Length: 846  
Fragment?: false
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Protein
Q3UV09
Organism: Mus musculus/domesticus
Length: 827  
Fragment?: false
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Protein
B7ZNJ0
Organism: Mus musculus/domesticus
Length: 827  
Fragment?: false
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Protein
Q3UNK7
Organism: Mus musculus/domesticus
Length: 846  
Fragment?: false
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Protein
Q3UEW9
Organism: Mus musculus/domesticus
Length: 827  
Fragment?: false
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Publication
8437211 | -
First Author: Will C
Year: 1993
Journal: J Virol
Title: Marburg virus gene 4 encodes the virion membrane protein, a type I transmembrane glycoprotein.
Volume: 67
Issue: 3
Pages: 1203-10
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Publication
17005688 | -
First Author: Shimojima M
Year: 2006
Journal: J Virol
Title: Tyro3 family-mediated cell entry of Ebola and Marburg viruses.
Volume: 80
Issue: 20
Pages: 10109-16
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Publication
16775318 | -
First Author: Marzi A
Year: 2006
Journal: J Virol
Title: The signal peptide of the ebolavirus glycoprotein influences interaction with the cellular lectins DC-SIGN and DC-SIGNR.
Volume: 80
Issue: 13
Pages: 6305-17
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Publication
11152533 | -
First Author: Ito H
Year: 2001
Journal: J Virol
Title: Ebola virus glycoprotein: proteolytic processing, acylation, cell tropism, and detection of neutralizing antibodies.
Volume: 75
Issue: 3
Pages: 1576-80
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Publication
12482654 | -
First Author: Sui J
Year: 2002
Journal: Virology
Title: Evidence against Ebola virus sGP binding to human neutrophils by a specific receptor.
Volume: 303
Issue: 1
Pages: 9-14
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Publication
16051836 | -
First Author: Wahl-Jensen VM
Year: 2005
Journal: J Virol
Title: Effects of Ebola virus glycoproteins on endothelial cell activation and barrier function.
Volume: 79
Issue: 16
Pages: 10442-50
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Publication
15681442 | -
First Author: Wahl-Jensen V
Year: 2005
Journal: J Virol
Title: Role of Ebola virus secreted glycoproteins and virus-like particles in activation of human macrophages.
Volume: 79
Issue: 4
Pages: 2413-9
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Protein Domain
IPR014625 | GPC_FiloV
Type: Family
Description: Proteins in this family include the envelope glycoprotein and the pre-small/secreted glycoprotein from Filoviridae []. The envelope glycoprotein can be cleaved into 3 chains: GP1, GP2 and GP2-delta.GP1 is responsible for binding to the receptor(s), such as CD209 and CLEC4M, on target cells. These interactions not only facilitate virus cell entry, but also allow capture of viral particles by dendritic cells (DCs) and subsequent transmission to susceptible cells without DCs infection (trans infection) [].GP2 acts as a class I viral fusion protein. It is responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane []. GP1,2 peplomers mediates endothelial cell activation and decreases endothelial barrier function. It mediates activation of primary macrophages. At terminal stages of the viral infection, when its expression is high, GP1,2 down-modulates the expression of various host cell surface molecules that are essential for immune surveillance and cell adhesion [].GP2delta is part of the complex GP1,2delta released by host ADAM17 metalloprotease. This secreted complex may play a role in the pathogenesis of the virus by efficiently blocking the neutralizing antibodies that would otherwise neutralize the virus surface glycoproteins GP1,2. Might therefore contribute to the lack of inflammatory reaction seen during infection in spite the of extensive necrosis and massive virus production. GP1,2delta does not seem to be involved in activation of primary macrophage [].pre-small/secreted glycoprotein sGP seems to possess an anti-inflammatory activity as it can reverse the barrier-decreasing effects of TNF alpha. It might therefore contribute to the lack of inflammatory reaction seen during infection in spite the of extensive necrosis and massive virus production. It does not seem to be involved in activation of primary macrophages. It does not seem to interact specifically with neutrophils [, , , ].
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Protein
Q3UEC0
Organism: Mus musculus/domesticus
Length: 502  
Fragment?: true
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Publication
28855301 | J:273534
First Author: Thornton P
Year: 2017
Journal: EMBO Mol Med
Title: TREM2 shedding by cleavage at the H157-S158 bond is accelerated for the Alzheimer's disease-associated H157Y variant.
Volume: 9
Issue: 10
Pages: 1366-1378
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Publication
11897009 | J:126011
 
First Author: Gunn TM
Year: 2002
Journal: BMC Genet
Title: Identification and preliminary characterization of mouse Adam33.
Volume: 3
Pages: 2
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Publication
15920158 | J:98813
First Author: Mahmoodi M
Year: 2005
Journal: Am J Pathol
Title: Lack of tissue inhibitor of metalloproteinases-3 results in an enhanced inflammatory response in antigen-induced arthritis.
Volume: 166
Issue: 6
Pages: 1733-40
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