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Search results 1 to 100 out of 171 for Col4a3

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Type Details Score
Publication
8956999 | J:37963
First Author: Cosgrove D
Year: 1996
Journal: Genes Dev
Title: Collagen COL4A3 knockout: a mouse model for autosomal Alport syndrome.
Volume: 10
Issue: 23
Pages: 2981-92
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Publication
10534397 | J:58257
First Author: Lu W
Year: 1999
Journal: Genomics
Title: Insertional mutation of the collagen genes Col4a3 and Col4a4 in a mouse model of Alport syndrome.
Volume: 61
Issue: 2
Pages: 113-24
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Publication
26555339 | J:269882
First Author: Kim M
Year: 2015
Journal: PLoS One
Title: Progression of Alport Kidney Disease in Col4a3 Knock Out Mice Is Independent of Sex or Macrophage Depletion by Clodronate Treatment.
Volume: 10
Issue: 11
Pages: e0141231
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Publication
33718859 | J:330819
 
First Author: Odiatis C
Year: 2021
Journal: Matrix Biol Plus
Title: A glycine substitution in the collagenous domain of Col4a3 in mice recapitulates late onset Alport syndrome.
Volume: 9
Pages: 100053
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Publication
33774048 | J:313275
 
First Author: Pokidysheva EN
Year: 2021
Journal: J Biol Chem
Title: Collagen IVα345 dysfunction in glomerular basement membrane diseases. I. Discovery of a COL4A3 variant in familial Goodpasture's and Alport diseases.
Volume: 296
Pages: 100590
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Publication
24480069 | J:209434
 
First Author: Rubel D
Year: 2014
Journal: Matrix Biol
Title: Collagen receptors integrin alpha2beta1 and discoidin domain receptor 1 regulate maturation of the glomerular basement membrane and loss of integrin alpha2beta1 delays kidney fibrosis in COL4A3 knockout mice.
Volume: 34
Pages: 13-21
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Publication
14507670 | J:109362
First Author: Heidet L
Year: 2003
Journal: Am J Pathol
Title: A human-mouse chimera of the alpha3alpha4alpha5(IV) collagen protomer rescues the renal phenotype in Col4a3-/- Alport mice.
Volume: 163
Issue: 4
Pages: 1633-44
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Publication
38561223 | J:352936
 
First Author: LeBleu VS
Year: 2024
Journal: Life Sci Alliance
Title: Genetic reprogramming with stem cells regenerates glomerular epithelial podocytes in Alport syndrome.
Volume: 7
Issue: 6
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Publication
30724107 | J:278133
First Author: Funk SD
Year: 2019
Journal: Am J Physiol Renal Physiol
Title: Endothelial cell-specific collagen type IV-α3 expression does not rescue Alport syndrome in Col4a3-/- mice.
Volume: 316
Issue: 5
Pages: F830-F837
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Publication
24262798 | J:330820
First Author: Pieri M
Year: 2014
Journal: J Am Soc Nephrol
Title: Evidence for activation of the unfolded protein response in collagen IV nephropathies.
Volume: 25
Issue: 2
Pages: 260-75
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Publication
16775036 | J:128226
First Author: Beirowski B
Year: 2006
Journal: J Am Soc Nephrol
Title: Chronic renal failure and shortened lifespan in COL4A3+/- mice: an animal model for thin basement membrane nephropathy.
Volume: 17
Issue: 7
Pages: 1986-94
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Publication
12631109 | J:129179
First Author: Gross O
Year: 2003
Journal: Kidney Int
Title: Preemptive ramipril therapy delays renal failure and reduces renal fibrosis in COL4A3-knockout mice with Alport syndrome.
Volume: 63
Issue: 2
Pages: 438-46
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Publication
17055234 | J:117359
First Author: Baxter RM
Year: 2007
Journal: Matrix Biol
Title: The plant pathogenesis related protein GLIPR-2 is highly expressed in fibrotic kidney and promotes epithelial to mesenchymal transition in vitro.
Volume: 26
Issue: 1
Pages: 20-9
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Publication
22739976 | J:198168
First Author: Dai B
Year: 2012
Journal: Kidney Int
Title: Assessment of 24,25(OH)2D levels does not support FGF23-mediated catabolism of vitamin D metabolites.
Volume: 82
Issue: 10
Pages: 1061-70
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Publication
28249676 | J:294019
First Author: Bae EH
Year: 2017
Journal: Kidney Int
Title: Murine recombinant angiotensin-converting enzyme 2 attenuates kidney injury in experimental Alport syndrome.
Volume: 91
Issue: 6
Pages: 1347-1361
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Publication
11839593 | J:74499
First Author: Andrews KL
Year: 2002
Journal: Am J Pathol
Title: Quantitative trait loci influence renal disease progression in a mouse model of Alport syndrome.
Volume: 160
Issue: 2
Pages: 721-30
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Publication
9682811 | J:91619
First Author: Cosgrove D
Year: 1998
Journal: Hear Res
Title: Ultrastructural, physiological, and molecular defects in the inner ear of a gene-knockout mouse model for autosomal Alport syndrome.
Volume: 121
Issue: 1-2
Pages: 84-98
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Publication
32822386 | J:293941
First Author: Dufek B
Year: 2020
Journal: PLoS One
Title: RNA-seq analysis of gene expression profiles in isolated stria vascularis from wild-type and Alport mice reveals key pathways underling Alport strial pathogenesis.
Volume: 15
Issue: 8
Pages: e0237907
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Publication
12039968 | J:78616
First Author: Hamano Y
Year: 2002
Journal: J Biol Chem
Title: Determinants of vascular permeability in the kidney glomerulus.
Volume: 277
Issue: 34
Pages: 31154-62
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28916834 | J:255555
First Author: Tsuji K
Year: 2017
Journal: Sci Rep
Title: Ultrastructural Characterization of the Glomerulopathy in Alport Mice by Helium Ion Scanning Microscopy (HIM).
Volume: 7
Issue: 1
Pages: 11696
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Publication
27377778 | J:276350
 
First Author: Murata T
Year: 2016
Journal: Sci Rep
Title: COL4A6 is dispensable for autosomal recessive Alport syndrome.
Volume: 6
Pages: 29450
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Publication
24522496 | J:223185
First Author: Korstanje R
Year: 2014
Journal: Kidney Int
Title: A mouse Col4a4 mutation causing Alport glomerulosclerosis with abnormal collagen α3α4α5(IV) trimers.
Volume: 85
Issue: 6
Pages: 1461-8
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Publication
22031097 | J:329780
First Author: Stubbs JR
Year: 2012
Journal: J Bone Miner Res
Title: Longitudinal evaluation of FGF23 changes and mineral metabolism abnormalities in a mouse model of chronic kidney disease.
Volume: 27
Issue: 1
Pages: 38-46
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Publication
33340991 | J:313467
 
First Author: Kim JJ
Year: 2021
Journal: EBioMedicine
Title: Discoidin domain receptor 1 activation links extracellular matrix to podocyte lipotoxicity in Alport syndrome.
Volume: 63
Pages: 103162
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Publication
25111226 | J:214832
First Author: Zeisberg M
Year: 2014
Journal: Am J Pathol
Title: Thrombospondin-1 deficiency causes a shift from fibroproliferative to inflammatory kidney disease and delays onset of renal failure.
Volume: 184
Issue: 10
Pages: 2687-98
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Publication
23236390 | J:195680
First Author: Steenhard BM
Year: 2012
Journal: PLoS One
Title: Upregulated expression of integrin α1 in mesangial cells and integrin α3 and vimentin in podocytes of Col4a3-null (Alport) mice.
Volume: 7
Issue: 12
Pages: e50745
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Publication
16877525 | J:120399
First Author: Miyoshi T
Year: 2006
Journal: FASEB J
Title: Tumor-specific expression of the RGD-alpha3(IV)NC1 domain suppresses endothelial tube formation and tumor growth in mice.
Volume: 20
Issue: 11
Pages: 1904-6
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Publication
23817022 | J:200001
First Author: LeBleu VS
Year: 2013
Journal: Nat Med
Title: Origin and function of myofibroblasts in kidney fibrosis.
Volume: 19
Issue: 8
Pages: 1047-53
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Publication
24262794 | J:207595
First Author: Lin X
Year: 2014
Journal: J Am Soc Nephrol
Title: Feasibility of repairing glomerular basement membrane defects in Alport syndrome.
Volume: 25
Issue: 4
Pages: 687-92
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Publication
25415439 | J:219368
First Author: Gomez IG
Year: 2015
Journal: J Clin Invest
Title: Anti-microRNA-21 oligonucleotides prevent Alport nephropathy progression by stimulating metabolic pathways.
Volume: 125
Issue: 1
Pages: 141-56
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Publication
21123730 | J:171180
First Author: Wyss HM
Year: 2011
Journal: Am J Physiol Cell Physiol
Title: Biophysical properties of normal and diseased renal glomeruli.
Volume: 300
Issue: 3
Pages: C397-405
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8947561 | J:37017
First Author: Miner JH
Year: 1996
Journal: J Cell Biol
Title: Molecular and functional defects in kidneys of mice lacking collagen alpha 3(IV): implications for Alport syndrome.
Volume: 135
Issue: 5
Pages: 1403-13
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Publication
22371398 | J:183249
First Author: Zhang JJ
Year: 2012
Journal: J Immunol
Title: Murine membranous nephropathy: immunization with α3(IV) collagen fragment induces subepithelial immune complexes and FcγR-independent nephrotic syndrome.
Volume: 188
Issue: 7
Pages: 3268-77
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Publication
22553158 | J:189436
First Author: Ryu M
Year: 2012
Journal: J Pathol
Title: Plasma leakage through glomerular basement membrane ruptures triggers the proliferation of parietal epithelial cells and crescent formation in non-inflammatory glomerular injury.
Volume: 228
Issue: 4
Pages: 482-94
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16816359 | J:110183
First Author: Rao VH
Year: 2006
Journal: Am J Pathol
Title: Role for macrophage metalloelastase in glomerular basement membrane damage associated with alport syndrome.
Volume: 169
Issue: 1
Pages: 32-46
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Publication
27151924 | J:290343
First Author: Andersen K
Year: 2017
Journal: J Am Soc Nephrol
Title: Intestinal Dysbiosis, Barrier Dysfunction, and Bacterial Translocation Account for CKD-Related Systemic Inflammation.
Volume: 28
Issue: 1
Pages: 76-83
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Publication
35461329 | J:333668
First Author: Hanudel MR
Year: 2022
Journal: Sci Rep
Title: Renoprotective effects of ferric citrate in a mouse model of chronic kidney disease.
Volume: 12
Issue: 1
Pages: 6695
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Publication
20962742 | J:186887
First Author: Ryu M
Year: 2011
Journal: Kidney Int
Title: Bacterial CpG-DNA accelerates Alport glomerulosclerosis by inducing an M1 macrophage phenotype and tumor necrosis factor-α-mediated podocyte loss.
Volume: 79
Issue: 2
Pages: 189-98
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Publication
34341345 | J:323035
First Author: Wright MB
Year: 2021
Journal: Nat Commun
Title: Compounds targeting OSBPL7 increase ABCA1-dependent cholesterol efflux preserving kidney function in two models of kidney disease.
Volume: 12
Issue: 1
Pages: 4662
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Publication
10777566 | J:120234
First Author: Kalluri R
Year: 2000
Journal: J Biol Chem
Title: Assembly of type IV collagen. Insights from alpha3(IV) collagen-deficient mice.
Volume: 275
Issue: 17
Pages: 12719-24
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Publication
31390839 | J:286352
 
First Author: Suh SH
Year: 2019
Journal: Int J Mol Sci
Title: Olmesartan Attenuates Kidney Fibrosis in a Murine Model of Alport Syndrome by Suppressing Tubular Expression of TGFβ.
Volume: 20
Issue: 15
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Publication
25777062 | J:220732
First Author: Bae EH
Year: 2015
Journal: Am J Pathol
Title: Characterization of the intrarenal renin-angiotensin system in experimental alport syndrome.
Volume: 185
Issue: 5
Pages: 1423-35
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Publication
36966182 | J:334822
First Author: Bollenbecker S
Year: 2023
Journal: Sci Rep
Title: Phosphate induces inflammation and exacerbates injury from cigarette smoke in the bronchial epithelium.
Volume: 13
Issue: 1
Pages: 4898
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Publication
35203245 | J:321620
 
First Author: Rubel D
Year: 2022
Journal: Cells
Title: Anti-microRNA-21 Therapy on Top of ACE Inhibition Delays Renal Failure in Alport Syndrome Mouse Models.
Volume: 11
Issue: 4
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Publication
17290292 | J:188471
First Author: Cosgrove D
Year: 2007
Journal: Kidney Int
Title: Choosing a mouse model to study the molecular pathobiology of Alport glomerulonephritis.
Volume: 71
Issue: 7
Pages: 615-8
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Publication
16723981 | J:188472
First Author: Ninichuk V
Year: 2006
Journal: Kidney Int
Title: Multipotent mesenchymal stem cells reduce interstitial fibrosis but do not delay progression of chronic kidney disease in collagen4A3-deficient mice.
Volume: 70
Issue: 1
Pages: 121-9
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Publication
15855646 | J:98449
First Author: Gratton MA
Year: 2005
Journal: Am J Pathol
Title: Matrix metalloproteinase dysregulation in the stria vascularis of mice with Alport syndrome: implications for capillary basement membrane pathology.
Volume: 166
Issue: 5
Pages: 1465-74
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Publication
32144368 | J:286364
First Author: Choi HS
Year: 2020
Journal: Sci Rep
Title: Angiotensin-[1-7] attenuates kidney injury in experimental Alport syndrome.
Volume: 10
Issue: 1
Pages: 4225
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Publication
10571774 | J:59648
First Author: Sayers R
Year: 1999
Journal: Kidney Int
Title: Role for transforming growth factor-beta1 in alport renal disease progression.
Volume: 56
Issue: 5
Pages: 1662-73
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19156777 | J:146525
First Author: Clauss S
Year: 2009
Journal: J Pathol
Title: Ccl2/Mcp-1 blockade reduces glomerular and interstitial macrophages but does not ameliorate renal pathology in collagen4A3-deficient mice with autosomal recessive Alport nephropathy.
Volume: 218
Issue: 1
Pages: 40-7
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Publication
35271660 | J:322505
First Author: Iida M
Year: 2022
Journal: PLoS One
Title: TNF-α induces Claudin-1 expression in renal tubules in Alport mice.
Volume: 17
Issue: 3
Pages: e0265081
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Publication
11447218 | J:71378
First Author: Sampson NS
Year: 2001
Journal: J Biol Chem
Title: Global gene expression analysis reveals a role for the alpha 1 integrin in renal pathogenesis.
Volume: 276
Issue: 36
Pages: 34182-8
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11073824 | J:91620
First Author: Cosgrove D
Year: 2000
Journal: Am J Pathol
Title: Integrin alpha1beta1 and transforming growth factor-beta1 play distinct roles in alport glomerular pathogenesis and serve as dual targets for metabolic therapy.
Volume: 157
Issue: 5
Pages: 1649-59
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Publication
18258846 | J:132013
First Author: Cosgrove D
Year: 2008
Journal: Am J Pathol
Title: Integrin alpha1beta1 regulates matrix metalloproteinases via P38 mitogen-activated protein kinase in mesangial cells: implications for Alport syndrome.
Volume: 172
Issue: 3
Pages: 761-73
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Publication
20307660 | J:161975
First Author: Gross O
Year: 2010
Journal: Matrix Biol
Title: Loss of collagen-receptor DDR1 delays renal fibrosis in hereditary type IV collagen disease.
Volume: 29
Issue: 5
Pages: 346-56
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Publication
17200187 | J:117045
First Author: Hahm K
Year: 2007
Journal: Am J Pathol
Title: Alphav beta6 integrin regulates renal fibrosis and inflammation in Alport mouse.
Volume: 170
Issue: 1
Pages: 110-25
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Publication
18180701 | J:131825
First Author: Lebleu VS
Year: 2008
Journal: Lab Invest
Title: Lymphocytes are dispensable for glomerulonephritis but required for renal interstitial fibrosis in matrix defect-induced Alport renal disease.
Volume: 88
Issue: 3
Pages: 284-92
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Publication
30827511 | J:292758
First Author: van Roeyen CRC
Year: 2019
Journal: Kidney Int
Title: Identification of platelet-derived growth factor C as a mediator of both renal fibrosis and hypertension.
Volume: 95
Issue: 5
Pages: 1103-1119
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Publication
22095946 | J:226590
First Author: López-Guisa JM
Year: 2012
Journal: J Am Soc Nephrol
Title: Mannose receptor 2 attenuates renal fibrosis.
Volume: 23
Issue: 2
Pages: 236-51
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Publication
20197625 | J:158731
First Author: Tanaka M
Year: 2010
Journal: J Clin Invest
Title: Loss of the BMP antagonist USAG-1 ameliorates disease in a mouse model of the progressive hereditary kidney disease Alport syndrome.
Volume: 120
Issue: 3
Pages: 768-77
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Publication
22970174 | J:286318
First Author: Dai B
Year: 2012
Journal: PLoS One
Title: A comparative transcriptome analysis identifying FGF23 regulated genes in the kidney of a mouse CKD model.
Volume: 7
Issue: 9
Pages: e44161
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Publication
23303673 | J:193250
First Author: Olaru F
Year: 2013
Journal: J Immunol
Title: Proteolysis breaks tolerance toward intact α345(IV) collagen, eliciting novel anti-glomerular basement membrane autoantibodies specific for α345NC1 hexamers.
Volume: 190
Issue: 4
Pages: 1424-32
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Publication
27147675 | J:280769
First Author: Jarad G
Year: 2016
Journal: Am J Physiol Renal Physiol
Title: Albumin contributes to kidney disease progression in Alport syndrome.
Volume: 311
Issue: 1
Pages: F120-30
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Publication
35743114 | J:326264
 
First Author: Irion CI
Year: 2022
Journal: Int J Mol Sci
Title: Col4a3-/- Mice on Balb/C Background Have Less Severe Cardiorespiratory Phenotype and SGLT2 Over-Expression Compared to 129x1/SvJ and C57Bl/6 Backgrounds.
Volume: 23
Issue: 12
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Publication
20847057 | J:167404
First Author: LeBleu V
Year: 2010
Journal: J Biol Chem
Title: Identification of the NC1 domain of {alpha}3 chain as critical for {alpha}3{alpha}4{alpha}5 type IV collagen network assembly.
Volume: 285
Issue: 53
Pages: 41874-85
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23443925 | J:196066
First Author: Touchberry CD
Year: 2013
Journal: Am J Physiol Endocrinol Metab
Title: FGF23 is a novel regulator of intracellular calcium and cardiac contractility in addition to cardiac hypertrophy.
Volume: 304
Issue: 8
Pages: E863-73
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Publication
25053401 | J:215598
First Author: Silswal N
Year: 2014
Journal: Am J Physiol Endocrinol Metab
Title: FGF23 directly impairs endothelium-dependent vasorelaxation by increasing superoxide levels and reducing nitric oxide bioavailability.
Volume: 307
Issue: 5
Pages: E426-36
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7962065 | J:21122
First Author: Miner JH
Year: 1994
Journal: J Cell Biol
Title: Collagen IV alpha 3, alpha 4, and alpha 5 chains in rodent basal laminae: sequence, distribution, association with laminins, and developmental switches.
Volume: 127
Issue: 3
Pages: 879-91
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29263159 | J:280129
First Author: Funk SD
Year: 2018
Journal: J Am Soc Nephrol
Title: Pathogenicity of a Human Laminin β2 Mutation Revealed in Models of Alport Syndrome.
Volume: 29
Issue: 3
Pages: 949-960
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Publication
37079387 | J:336552
 
First Author: Martinez-Calle M
Year: 2023
Journal: J Clin Invest
Title: Transcription factor HNF4α2 promotes osteogenesis and prevents bone abnormalities in mice with renal osteodystrophy.
Volume: 133
Issue: 11
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15710885 | J:97878
First Author: Sund M
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Function of endogenous inhibitors of angiogenesis as endothelium-specific tumor suppressors.
Volume: 102
Issue: 8
Pages: 2934-9
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35302487 | J:322897
   
First Author: Czaya B
Year: 2022
Journal: Elife
Title: Hyperphosphatemia increases inflammation to exacerbate anemia and skeletal muscle wasting independently of FGF23-FGFR4 signaling.
Volume: 11
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31146816 | J:289309
First Author: Yousefi K
Year: 2019
Journal: J Am Coll Cardiol
Title: Osteopontin Promotes Left Ventricular Diastolic Dysfunction Through a Mitochondrial Pathway.
Volume: 73
Issue: 21
Pages: 2705-2718
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Publication
38961844 | J:354275
First Author: Duara J
Year: 2024
Journal: Am J Physiol Renal Physiol
Title: Oxysterol-binding protein-like 7 deficiency leads to ER stress-mediated apoptosis in podocytes and proteinuria.
Volume: 327
Issue: 3
Pages: F340-F350
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Publication
21953121 | J:180002
First Author: Ryu M
Year: 2012
Journal: J Pathol
Title: Tumour necrosis factor-α drives Alport glomerulosclerosis in mice by promoting podocyte apoptosis.
Volume: 226
Issue: 1
Pages: 120-31
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12842087 | J:120382
First Author: Hamano Y
Year: 2003
Journal: Cancer Cell
Title: Physiological levels of tumstatin, a fragment of collagen IV alpha3 chain, are generated by MMP-9 proteolysis and suppress angiogenesis via alphaV beta3 integrin.
Volume: 3
Issue: 6
Pages: 589-601
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Publication
20864678 | J:166258
First Author: Dennis J
Year: 2010
Journal: Am J Pathol
Title: Collagen XIII induced in vascular endothelium mediates alpha1beta1 integrin-dependent transmigration of monocytes in renal fibrosis.
Volume: 177
Issue: 5
Pages: 2527-40
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Publication
20860797 | J:323413
 
First Author: Girgert R
Year: 2010
Journal: Fibrogenesis Tissue Repair
Title: Integrin α2-deficient mice provide insights into specific functions of collagen receptors in the kidney.
Volume: 3
Pages: 19
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Publication
16509766 | J:134125
First Author: Zeisberg M
Year: 2006
Journal: PLoS Med
Title: Stage-specific action of matrix metalloproteinases influences progressive hereditary kidney disease.
Volume: 3
Issue: 4
Pages: e100
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Publication
29563333 | J:293554
 
First Author: Ding W
Year: 2018
Journal: JCI Insight
Title: Osteopontin deficiency ameliorates Alport pathology by preventing tubular metabolic deficits.
Volume: 3
Issue: 6
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Publication
34049963 | J:338638
First Author: Randles MJ
Year: 2021
Journal: J Am Soc Nephrol
Title: Identification of an Altered Matrix Signature in Kidney Aging and Disease.
Volume: 32
Issue: 7
Pages: 1713-1732
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Publication
16769745 | J:128227
First Author: Kang JS
Year: 2006
Journal: J Am Soc Nephrol
Title: Loss of alpha3/alpha4(IV) collagen from the glomerular basement membrane induces a strain-dependent isoform switch to alpha5alpha6(IV) collagen associated with longer renal survival in Col4a3-/- Alport mice.
Volume: 17
Issue: 7
Pages: 1962-9
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Publication
24140714 | J:206528
First Author: David V
Year: 2013
Journal: Endocrinology
Title: Calcium regulates FGF-23 expression in bone.
Volume: 154
Issue: 12
Pages: 4469-82
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Publication
24915008 | J:218570
First Author: Delimont D
Year: 2014
Journal: PLoS One
Title: Laminin α2-mediated focal adhesion kinase activation triggers Alport glomerular pathogenesis.
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