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Search results 1 to 100 out of 123 for Lig4

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Category: Publication
Type Details Score
Publication
First Author: Rucci F
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Homozygous DNA ligase IV R278H mutation in mice leads to leaky SCID and represents a model for human LIG4 syndrome.
Volume: 107
Issue: 7
Pages: 3024-9
Publication
First Author: Friesner J
Year: 2003
Journal: Plant J
Title: Ku80- and DNA ligase IV-deficient plants are sensitive to ionizing radiation and defective in T-DNA integration.
Volume: 34
Issue: 4
Pages: 427-40
Publication
First Author: Iliakis G
Year: 2009
Journal: Radiother Oncol
Title: Backup pathways of NHEJ in cells of higher eukaryotes: cell cycle dependence.
Volume: 92
Issue: 3
Pages: 310-5
Publication
First Author: Wang H
Year: 2001
Journal: Nucleic Acids Res
Title: Genetic evidence for the involvement of DNA ligase IV in the DNA-PK-dependent pathway of non-homologous end joining in mammalian cells.
Volume: 29
Issue: 8
Pages: 1653-60
Publication  
First Author: Jun S
Year: 2016
Journal: Nat Commun
Title: LIG4 mediates Wnt signalling-induced radioresistance.
Volume: 7
Pages: 10994
Publication      
First Author: Zhong X
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for posey.
Publication      
First Author: Zhong X
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for posey2.
Publication
First Author: Nijnik A
Year: 2007
Journal: Nature
Title: DNA repair is limiting for haematopoietic stem cells during ageing.
Volume: 447
Issue: 7145
Pages: 686-90
Publication
First Author: Han L
Year: 2008
Journal: J Exp Med
Title: Altered kinetics of nonhomologous end joining and class switch recombination in ligase IV-deficient B cells.
Volume: 205
Issue: 12
Pages: 2745-53
Publication
First Author: Nijnik A
Year: 2009
Journal: J Clin Invest
Title: Impaired lymphocyte development and antibody class switching and increased malignancy in a murine model of DNA ligase IV syndrome.
Volume: 119
Issue: 6
Pages: 1696-705
Publication
First Author: Han L
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: X-ray repair cross-complementing protein 1 (XRCC1) deficiency enhances class switch recombination and is permissive for alternative end joining.
Volume: 109
Issue: 12
Pages: 4604-8
Publication
First Author: Sharpless NE
Year: 2001
Journal: Mol Cell
Title: Impaired nonhomologous end-joining provokes soft tissue sarcomas harboring chromosomal translocations, amplifications, and deletions.
Volume: 8
Issue: 6
Pages: 1187-96
Publication
First Author: Park J
Year: 2016
Journal: J Immunol
Title: The DNA Ligase IV Syndrome R278H Mutation Impairs B Lymphopoiesis via Error-Prone Nonhomologous End-Joining.
Volume: 196
Issue: 1
Pages: 244-55
Publication
First Author: Mills KD
Year: 2004
Journal: Genes Dev
Title: Rad54 and DNA Ligase IV cooperate to maintain mammalian chromatid stability.
Volume: 18
Issue: 11
Pages: 1283-92
Publication
First Author: Frank KM
Year: 2000
Journal: Mol Cell
Title: DNA ligase IV deficiency in mice leads to defective neurogenesis and embryonic lethality via the p53 pathway.
Volume: 5
Issue: 6
Pages: 993-1002
Publication
First Author: Kondo N
Year: 2009
Journal: Biochem Biophys Res Commun
Title: DNA ligase IV as a new molecular target for temozolomide.
Volume: 387
Issue: 4
Pages: 656-60
Publication
First Author: Sekiguchi J
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Genetic interactions between ATM and the nonhomologous end-joining factors in genomic stability and development.
Volume: 98
Issue: 6
Pages: 3243-8
Publication
First Author: Gu Y
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Defective embryonic neurogenesis in Ku-deficient but not DNA-dependent protein kinase catalytic subunit-deficient mice.
Volume: 97
Issue: 6
Pages: 2668-73
Publication
First Author: Barnes DE
Year: 1998
Journal: Curr Biol
Title: Targeted disruption of the gene encoding DNA ligase IV leads to lethality in embryonic mice.
Volume: 8
Issue: 25
Pages: 1395-8
Publication
First Author: Wang YG
Year: 2004
Journal: J Biol Chem
Title: Phosphorylation and regulation of DNA ligase IV stability by DNA-dependent protein kinase.
Volume: 279
Issue: 36
Pages: 37282-90
Publication
First Author: Simsek D
Year: 2011
Journal: PLoS Genet
Title: DNA ligase III promotes alternative nonhomologous end-joining during chromosomal translocation formation.
Volume: 7
Issue: 6
Pages: e1002080
Publication
First Author: Kim J
Year: 2017
Journal: Histochem Cell Biol
Title: Involvement of Atm and Trp53 in neural cell loss due to Terf2 inactivation during mouse brain development.
Volume: 148
Issue: 5
Pages: 489-501
Publication
First Author: Boboila C
Year: 2010
Journal: J Exp Med
Title: Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4.
Volume: 207
Issue: 2
Pages: 417-27
Publication
First Author: Gatz SA
Year: 2011
Journal: J Neurosci
Title: Requirement for DNA ligase IV during embryonic neuronal development.
Volume: 31
Issue: 27
Pages: 10088-100
Publication
First Author: Shull ER
Year: 2009
Journal: Genes Dev
Title: Differential DNA damage signaling accounts for distinct neural apoptotic responses in ATLD and NBS.
Volume: 23
Issue: 2
Pages: 171-80
Publication
First Author: Lun MP
Year: 2019
Journal: Am J Pathol
Title: Spatiotemporal Gradient of Cortical Neuron Death Contributes to Microcephaly in Knock-In Mouse Model of Ligase 4 Syndrome.
Volume: 189
Issue: 12
Pages: 2440-2449
Publication
First Author: Smogorzewska A
Year: 2002
Journal: Curr Biol
Title: DNA ligase IV-dependent NHEJ of deprotected mammalian telomeres in G1 and G2.
Volume: 12
Issue: 19
Pages: 1635-44
Publication
First Author: Pierce AJ
Year: 2001
Journal: Mol Cell
Title: NHEJ deficiency and disease.
Volume: 8
Issue: 6
Pages: 1160-1
Publication
First Author: Wray J
Year: 2010
Journal: Cancer Genet Cytogenet
Title: The transposase domain protein Metnase/SETMAR suppresses chromosomal translocations.
Volume: 200
Issue: 2
Pages: 184-90
Publication
First Author: Riballo E
Year: 2009
Journal: Nucleic Acids Res
Title: XLF-Cernunnos promotes DNA ligase IV-XRCC4 re-adenylation following ligation.
Volume: 37
Issue: 2
Pages: 482-92
Publication
First Author: Karanjawala ZE
Year: 2002
Journal: DNA Repair (Amst)
Title: The embryonic lethality in DNA ligase IV-deficient mice is rescued by deletion of Ku: implications for unifying the heterogeneous phenotypes of NHEJ mutants.
Volume: 1
Issue: 12
Pages: 1017-26
Publication
First Author: Karanjawala ZE
Year: 1999
Journal: Curr Biol
Title: The nonhomologous DNA end joining pathway is important for chromosome stability in primary fibroblasts.
Volume: 9
Issue: 24
Pages: 1501-4
Publication
First Author: Van Nguyen T
Year: 2007
Journal: J Exp Med
Title: DNA damage-induced cellular senescence is sufficient to suppress tumorigenesis: a mouse model.
Volume: 204
Issue: 6
Pages: 1453-61
Publication
First Author: Tavana O
Year: 2010
Journal: Diabetes
Title: Absence of p53-dependent apoptosis combined with nonhomologous end-joining deficiency leads to a severe diabetic phenotype in mice.
Volume: 59
Issue: 1
Pages: 135-42
Publication
First Author: Lee Y
Year: 2002
Journal: Cancer Res
Title: DNA ligase IV suppresses medulloblastoma formation.
Volume: 62
Issue: 22
Pages: 6395-9
Publication
First Author: Cortizas EM
Year: 2013
Journal: J Immunol
Title: Alternative end-joining and classical nonhomologous end-joining pathways repair different types of double-strand breaks during class-switch recombination.
Volume: 191
Issue: 11
Pages: 5751-63
Publication
First Author: Frank KM
Year: 1998
Journal: Nature
Title: Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV.
Volume: 396
Issue: 6707
Pages: 173-7
Publication
First Author: Konishi A
Year: 2008
Journal: Genes Dev
Title: Cell cycle control of telomere protection and NHEJ revealed by a ts mutation in the DNA-binding domain of TRF2.
Volume: 22
Issue: 9
Pages: 1221-30
Publication
First Author: Ferguson DO
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations.
Volume: 97
Issue: 12
Pages: 6630-3
Publication
First Author: Dooley J
Year: 2016
Journal: Nat Genet
Title: Genetic predisposition for beta cell fragility underlies type 1 and type 2 diabetes.
Volume: 48
Issue: 5
Pages: 519-27
Publication
First Author: Bentley DJ
Year: 2002
Journal: J Cell Sci
Title: DNA ligase I null mouse cells show normal DNA repair activity but altered DNA replication and reduced genome stability.
Volume: 115
Issue: Pt 7
Pages: 1551-61
Publication
First Author: Tkáč J
Year: 2016
Journal: Mol Cell
Title: HELB Is a Feedback Inhibitor of DNA End Resection.
Volume: 61
Issue: 3
Pages: 405-418
Publication
First Author: Peuscher MH
Year: 2011
Journal: Nat Cell Biol
Title: DNA-damage response and repair activities at uncapped telomeres depend on RNF8.
Volume: 13
Issue: 9
Pages: 1139-45
Publication
First Author: Gapud EJ
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Ataxia telangiectasia mutated (Atm) and DNA-PKcs kinases have overlapping activities during chromosomal signal joint formation.
Volume: 108
Issue: 5
Pages: 2022-7
Publication
First Author: Boboila C
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Alternative end-joining catalyzes robust IgH locus deletions and translocations in the combined absence of ligase 4 and Ku70.
Volume: 107
Issue: 7
Pages: 3034-9
Publication
First Author: Boboila C
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Robust chromosomal DNA repair via alternative end-joining in the absence of X-ray repair cross-complementing protein 1 (XRCC1).
Volume: 109
Issue: 7
Pages: 2473-8
Publication
First Author: Green MR
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Signatures of murine B-cell development implicate Yy1 as a regulator of the germinal center-specific program.
Volume: 108
Issue: 7
Pages: 2873-8
Publication
First Author: Buis J
Year: 2008
Journal: Cell
Title: Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation.
Volume: 135
Issue: 1
Pages: 85-96
Publication
First Author: Lottersberger F
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Role of 53BP1 oligomerization in regulating double-strand break repair.
Volume: 110
Issue: 6
Pages: 2146-51
Publication
First Author: Yan CT
Year: 2007
Journal: Nature
Title: IgH class switching and translocations use a robust non-classical end-joining pathway.
Volume: 449
Issue: 7161
Pages: 478-82
Publication
First Author: Maser RS
Year: 2007
Journal: Mol Cell Biol
Title: DNA-dependent protein kinase catalytic subunit is not required for dysfunctional telomere fusion and checkpoint response in the telomerase-deficient mouse.
Volume: 27
Issue: 6
Pages: 2253-65
Publication
First Author: Barazzuol L
Year: 2015
Journal: J Cell Sci
Title: Low levels of endogenous or X-ray-induced DNA double-strand breaks activate apoptosis in adult neural stem cells.
Volume: 128
Issue: 19
Pages: 3597-606
Publication
First Author: Johnson NC
Year: 2008
Journal: Genes Dev
Title: Lymphatic endothelial cell identity is reversible and its maintenance requires Prox1 activity.
Volume: 22
Issue: 23
Pages: 3282-91
Publication
First Author: Canela A
Year: 2019
Journal: Mol Cell
Title: Topoisomerase II-Induced Chromosome Breakage and Translocation Is Determined by Chromosome Architecture and Transcriptional Activity.
Volume: 75
Issue: 2
Pages: 252-266.e8
Publication
First Author: Gostissa M
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Chromosomal location targets different MYC family gene members for oncogenic translocations.
Volume: 106
Issue: 7
Pages: 2265-70
Publication
First Author: Helmink BA
Year: 2011
Journal: Nature
Title: H2AX prevents CtIP-mediated DNA end resection and aberrant repair in G1-phase lymphocytes.
Volume: 469
Issue: 7329
Pages: 245-9
Publication
First Author: Maruyama T
Year: 2015
Journal: Nat Biotechnol
Title: Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining.
Volume: 33
Issue: 5
Pages: 538-42
Publication
First Author: Balmus G
Year: 2016
Journal: Genes Dev
Title: Synthetic lethality between PAXX and XLF in mammalian development.
Volume: 30
Issue: 19
Pages: 2152-2157
Publication
First Author: Gao Y
Year: 1998
Journal: Cell
Title: A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis.
Volume: 95
Issue: 7
Pages: 891-902
Publication
First Author: Frappart PO
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Recurrent genomic alterations characterize medulloblastoma arising from DNA double-strand break repair deficiency.
Volume: 106
Issue: 6
Pages: 1880-5
Publication
First Author: Zhu C
Year: 2002
Journal: Cell
Title: Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations.
Volume: 109
Issue: 7
Pages: 811-21
Publication
First Author: Sfeir A
Year: 2009
Journal: Cell
Title: Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication.
Volume: 138
Issue: 1
Pages: 90-103
Publication
First Author: Celli GB
Year: 2005
Journal: Nat Cell Biol
Title: DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion.
Volume: 7
Issue: 7
Pages: 712-8
Publication
First Author: Gurley KE
Year: 2009
Journal: EMBO Rep
Title: DNA-PK suppresses a p53-independent apoptotic response to DNA damage.
Volume: 10
Issue: 1
Pages: 87-93
Publication
First Author: Gostissa M
Year: 2009
Journal: Nature
Title: Long-range oncogenic activation of Igh-c-myc translocations by the Igh 3' regulatory region.
Volume: 462
Issue: 7274
Pages: 803-7
Publication
First Author: Sfeir A
Year: 2012
Journal: Science
Title: Removal of shelterin reveals the telomere end-protection problem.
Volume: 336
Issue: 6081
Pages: 593-7
Publication
First Author: Dimitrova N
Year: 2008
Journal: Nature
Title: 53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility.
Volume: 456
Issue: 7221
Pages: 524-8
Publication
First Author: Rommel PC
Year: 2013
Journal: PLoS One
Title: Fate mapping for activation-induced cytidine deaminase (AID) marks non-lymphoid cells during mouse development.
Volume: 8
Issue: 7
Pages: e69208
Publication
First Author: Zhou T
Year: 2013
Journal: Exp Hematol
Title: Myelodysplastic syndrome: an inability to appropriately respond to damaged DNA?
Volume: 41
Issue: 8
Pages: 665-74
Publication  
First Author: Mills KD
Year: 2003
Journal: Immunol Rev
Title: The role of DNA breaks in genomic instability and tumorigenesis.
Volume: 194
Pages: 77-95
Publication
First Author: Lee Y
Year: 2003
Journal: Cancer Res
Title: A molecular fingerprint for medulloblastoma.
Volume: 63
Issue: 17
Pages: 5428-37
Publication
First Author: Gao Y
Year: 2011
Journal: Nature
Title: DNA ligase III is critical for mtDNA integrity but not Xrcc1-mediated nuclear DNA repair.
Volume: 471
Issue: 7337
Pages: 240-4
Publication
First Author: Mirman Z
Year: 2018
Journal: Nature
Title: 53BP1-RIF1-shieldin counteracts DSB resection through CST- and Polα-dependent fill-in.
Volume: 560
Issue: 7716
Pages: 112-116
Publication
First Author: Lee Y
Year: 2000
Journal: Genes Dev
Title: Defective neurogenesis resulting from DNA ligase IV deficiency requires Atm.
Volume: 14
Issue: 20
Pages: 2576-80
Publication
First Author: Foster SS
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Cell cycle- and DNA repair pathway-specific effects of apoptosis on tumor suppression.
Volume: 109
Issue: 25
Pages: 9953-8
Publication
First Author: Orii KE
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Selective utilization of nonhomologous end-joining and homologous recombination DNA repair pathways during nervous system development.
Volume: 103
Issue: 26
Pages: 10017-22
Publication
First Author: Vats KR
Year: 2006
Journal: J Am Soc Nephrol
Title: A locus for renal malformations including vesico-ureteric reflux on chromosome 13q33-34.
Volume: 17
Issue: 4
Pages: 1158-67
Publication  
First Author: Wang XQ
Year: 2014
Journal: BMC Dev Biol
Title: G1 checkpoint establishment in vivo during embryonic liver development.
Volume: 14
Pages: 23
Publication
First Author: Shimada M
Year: 2015
Journal: EMBO J
Title: Polynucleotide kinase-phosphatase enables neurogenesis via multiple DNA repair pathways to maintain genome stability.
Volume: 34
Issue: 19
Pages: 2465-80
Publication
First Author: Lee Y
Year: 2014
Journal: J Neurosci
Title: Pot1a prevents telomere dysfunction and ATM-dependent neuronal loss.
Volume: 34
Issue: 23
Pages: 7836-44
Publication
First Author: Huse JT
Year: 2009
Journal: Brain Pathol
Title: Genetically engineered mouse models of brain cancer and the promise of preclinical testing.
Volume: 19
Issue: 1
Pages: 132-43
Publication
First Author: Lee Y
Year: 2012
Journal: Nat Neurosci
Title: Neurogenesis requires TopBP1 to prevent catastrophic replicative DNA damage in early progenitors.
Volume: 15
Issue: 6
Pages: 819-26
Publication      
First Author: The Australian Phenomics Facility at The Australian National University
Year: 2006
Journal: MGI Direct Data Submission
Title: Heritable mouse mutants from the ENU mutagenesis program at the Australian Phenomics Facility at The Australian National University
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication      
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer