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Search results 201 to 249 out of 249 for Kif2a

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Type Details Score
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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UniProt Feature
UniProt Feature
Begin: 1
Description: Kinesin-like protein KIF2A
Type: chain
End: 705
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HT Experiment
GSE222923 | Kif2a operates as a gatekeeper of nociception in sensory neurons [RNA-seq - 3 months]
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE222924 | Kif2a operates as a gatekeeper of nociception in sensory neurons [RNA-seq - 6 months]
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE240557 | Kif2a operates as a gatekeeper of nociception in sensory neurons [RNA-seq - 1 month]
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
26323690 | J:227522
First Author: Watanabe T
Year: 2015
Journal: J Cell Biol
Title: TTBK2 with EB1/3 regulates microtubule dynamics in migrating cells through KIF2A phosphorylation.
Volume: 210
Issue: 5
Pages: 737-51
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Allele
Kif2a<em1Yrn> | MGI:7546792
Name: kinesin family member 2A; endonuclease-mediated mutation 1, Avraham Yaron
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Protein
P28740
Organism: Mus musculus/domesticus
Length: 705  
Fragment?: false
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Protein
P28740-1
Organism: Mus musculus/domesticus
Length: 716  
Fragment?: false
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Protein
P28740-2
Organism: Mus musculus/domesticus
Length: 659  
Fragment?: false
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Protein
F6RLL5
Organism: Mus musculus/domesticus
Length: 96  
Fragment?: true
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Publication
18411309 | -
First Author: Jang CY
Year: 2008
Journal: J Cell Biol
Title: DDA3 recruits microtubule depolymerase Kif2a to spindle poles and controls spindle dynamics and mitotic chromosome movement.
Volume: 181
Issue: 2
Pages: 255-67
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Publication
9774330 | -
First Author: Santama N
Year: 1998
Journal: EMBO J
Title: KIF2beta, a new kinesin superfamily protein in non-neuronal cells, is associated with lysosomes and may be implicated in their centrifugal translocation.
Volume: 17
Issue: 20
Pages: 5855-67
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Protein Domain
IPR026658 | DDA3
Type: Family
Description: This family contains mammalian proline/serine-rich coiled-coil protein 1, also known as DDA3. DDA3 is a microtubule-destabilising protein that controls spindle dynamics and mitotic progression by regulating microtubule depolymerases, such as Kif2a and MCAK [, ]. Deletion of DDA3 causes spindle hyper-stabilisation, inter-kinectochore tension loss, chromosome congression defects. And this leads to unaligned chromosomes at metaphase and the accumulation of CENP-E (a plus end-motor protein) at kinectochore in these chromosomes []. It has also been suggested that DDA3 may participate in p53/TP53-regulated growth suppression [].
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Publication
10618717 | J:64940
First Author: Lo PK
Year: 1999
Journal: Oncogene
Title: Identification of a novel mouse p53 target gene DDA3.
Volume: 18
Issue: 54
Pages: 7765-74
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Protein
Q922A4
Organism: Mus musculus/domesticus
Length: 175  
Fragment?: false
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Publication
21426902 | -
First Author: Jang CY
Year: 2011
Journal: Biochem Biophys Res Commun
Title: DDA3 associates with MCAK and controls chromosome congression.
Volume: 407
Issue: 3
Pages: 610-4
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Publication
19564401 | J:150408
First Author: Peris L
Year: 2009
Journal: J Cell Biol
Title: Motor-dependent microtubule disassembly driven by tubulin tyrosination.
Volume: 185
Issue: 7
Pages: 1159-66
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Protein Domain
IPR026657 | DDA3/GTSE-1
Type: Family
Description: This is a family of phosphoproteins which includes proline/serine-rich coiled-coil protein 1 (PSRC1, also known as DDA3) and G2 and S phase-expressed protein 1 (GTSE1).DDA3 is a microtubule-destabilising protein that controls spindle dynamics and mitotic progression by regulating microtubule depolymerases, such as Kif2a and MCAK [, ]. Deletion of DDA3 causes spindle hyper-stabilisation, inter-kinectochore tension loss, chromosome congression defects. This leads to unaligned chromosomes at metaphase and the accumulation of CENP-E (a plus end-motor protein) at kinectochore in these chromosomes []. It has also been suggested that DDA3 may participate in p53/TP53-regulated growth suppression []. GTSE1 may be involved in p53-induced cell cycle arrest in G2/M phase by interfering with microtubule rearrangements that are required to enter mitosis []. When overexpressed, GTSE1 delays G2/M phase progression [].
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Protein
Q9D0P7
Organism: Mus musculus/domesticus
Length: 329  
Fragment?: false
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Protein
A2AEF3
Organism: Mus musculus/domesticus
Length: 172  
Fragment?: true
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Publication
9724637 | J:49836
First Author: Utrera R
Year: 1998
Journal: EMBO J
Title: A novel p53-inducible gene coding for a microtubule-localized protein with G2-phase-specific expression.
Volume: 17
Issue: 17
Pages: 5015-25
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Protein
Q8R080
Organism: Mus musculus/domesticus
Length: 741  
Fragment?: false
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Publication
15123706 | -
First Author: Nouet S
Year: 2004
Journal: J Biol Chem
Title: Trans-inactivation of receptor tyrosine kinases by novel angiotensin II AT2 receptor-interacting protein, ATIP.
Volume: 279
Issue: 28
Pages: 28989-97
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Protein
Q5HZI1
Organism: Mus musculus/domesticus
Length: 1210  
Fragment?: false
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Protein
A0A0R4J1L9
Organism: Mus musculus/domesticus
Length: 1210  
Fragment?: false
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Protein
A0A0R4J147
Organism: Mus musculus/domesticus
Length: 520  
Fragment?: false
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Protein
Q542Q3
Organism: Mus musculus/domesticus
Length: 741  
Fragment?: false
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Protein
E9Q8N4
Organism: Mus musculus/domesticus
Length: 759  
Fragment?: true
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Protein
D3Z7B3
Organism: Mus musculus/domesticus
Length: 123  
Fragment?: true
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Protein
A0A0R4J0N9
Organism: Mus musculus/domesticus
Length: 440  
Fragment?: false
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Protein
F6Q593
Organism: Mus musculus/domesticus
Length: 214  
Fragment?: true
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Protein
Q8BXV7
Organism: Mus musculus/domesticus
Length: 230  
Fragment?: false
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Protein
Q8K0Q3
Organism: Mus musculus/domesticus
Length: 104  
Fragment?: true
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Protein
D3Z2H5
Organism: Mus musculus/domesticus
Length: 92  
Fragment?: true
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Publication
20577264 | -
First Author: Liu XS
Year: 2010
Journal: EMBO Rep
Title: Polo-like kinase 1 phosphorylation of G2 and S-phase-expressed 1 protein is essential for p53 inactivation during G2 checkpoint recovery.
Volume: 11
Issue: 8
Pages: 626-32
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Publication
19794912 | -
First Author: Rodrigues-Ferreira S
Year: 2009
Journal: PLoS One
Title: 8p22 MTUS1 gene product ATIP3 is a novel anti-mitotic protein underexpressed in invasive breast carcinoma of poor prognosis.
Volume: 4
Issue: 10
Pages: e7239
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Publication
20889352 | -
First Author: Rodrigues-Ferreira S
Year: 2010
Journal: Trends Endocrinol Metab
Title: An ATIPical family of angiotensin II AT2 receptor-interacting proteins.
Volume: 21
Issue: 11
Pages: 684-90
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Publication
19327998 | -
First Author: Knowlton AL
Year: 2009
Journal: Curr Biol
Title: ICIS and Aurora B coregulate the microtubule depolymerase Kif2a.
Volume: 19
Issue: 9
Pages: 758-63
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Publication
16887298 | -
First Author: Di Benedetto M
Year: 2006
Journal: Gene
Title: Structural organization and expression of human MTUS1, a candidate 8p22 tumor suppressor gene encoding a family of angiotensin II AT2 receptor-interacting proteins, ATIP.
Volume: 380
Issue: 2
Pages: 127-36
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Protein Domain
IPR029786 | MTUS1
Type: Family
Description: This entry represents the microtubule-associated tumour suppressor (MTUS1) family, including AT2 receptor-interacting proteins (ATIPs) from mammals and Inner centromere Kin-I stimulator (ICIS) from Xenopus. The transcript variants of human MTUS1 gene can be classified into three major groups (ATIP1, ATIP3 and ATIP4) based on their tissue distribution and utilisation of its exons []. ATIP1, also known as MTSG1, interacts with the AT2 receptor and is involved in its activation. AT2 receptor could antagonise the effect of the AT1 receptor and generate anti-proliferative, anti-migratory and anti-inflammatory responses []. It may cooperate with AT2 to inactivate the receptor tyrosine kinases [].ATIP3 is a microtubule associated protein whose expression is diminished in breast cancer []. It localises at the mitotic spindle throughout mitosis and decorates the intercellular bridge during cytokinesis []. It is a homologue of the Xenopus ICIS protein, which is an inner centromere protein acting as a scaffold to bring the microtubule-depolymerising kinesins MCAK and Kif2A to the kinetochore []. ICIS may regulate kinesin depolymerase activity at the mitotic spindle and ensures proper chromosome segregation during mitosis []. ATIP4 may be involved in brain development and/or cognition [].
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Publication
15345747 | -
First Author: Ballif BA
Year: 2004
Journal: Mol Cell Proteomics
Title: Phosphoproteomic analysis of the developing mouse brain.
Volume: 3
Issue: 11
Pages: 1093-101
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Publication
23806337 | J:203468
First Author: Park J
Year: 2013
Journal: Mol Cell
Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.
Volume: 50
Issue: 6
Pages: 919-30
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
21183079 | J:292518
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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