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Search results 1 to 100 out of 168 for Rheb

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Category: Publication
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Type Details Score
Publication
15854902 | -
First Author: Long X
Year: 2005
Journal: Curr Biol
Title: Rheb binds and regulates the mTOR kinase.
Volume: 15
Issue: 8
Pages: 702-13
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Publication
12869586 | -
First Author: Inoki K
Year: 2003
Journal: Genes Dev
Title: Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling.
Volume: 17
Issue: 15
Pages: 1829-34
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Publication
16098514 | -
First Author: Tee AR
Year: 2005
Journal: FEBS Lett
Title: Analysis of mTOR signaling by the small G-proteins, Rheb and RhebL1.
Volume: 579
Issue: 21
Pages: 4763-8
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Publication
15728574 | -
First Author: Yu Y
Year: 2005
Journal: J Biol Chem
Title: Structural basis for the unique biological function of small GTPase RHEB.
Volume: 280
Issue: 17
Pages: 17093-100
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Publication
29104218 | -
 
First Author: Tatebe H
Year: 2017
Journal: Biomolecules
Title: Evolutionary Conservation of the Components in the TOR Signaling Pathways.
Volume: 7
Issue: 4
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Publication
21336308 | J:180541
First Author: Zheng M
Year: 2011
Journal: Nat Cell Biol
Title: Inactivation of Rheb by PRAK-mediated phosphorylation is essential for energy-depletion-induced suppression of mTORC1.
Volume: 13
Issue: 3
Pages: 263-72
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Publication
21321084 | J:170999
First Author: Goorden SM
Year: 2011
Journal: Mol Cell Biol
Title: Rheb is essential for murine development.
Volume: 31
Issue: 8
Pages: 1672-8
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Publication
33725483 | J:303709
First Author: Yang W
Year: 2021
Journal: Dev Cell
Title: Rheb mediates neuronal-activity-induced mitochondrial energetics through mTORC1-independent PDH activation.
Volume: 56
Issue: 6
Pages: 811-825.e6
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Publication
18708578 | J:138980
First Author: Mavrakis KJ
Year: 2008
Journal: Genes Dev
Title: Tumorigenic activity and therapeutic inhibition of Rheb GTPase.
Volume: 22
Issue: 16
Pages: 2178-88
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Publication
35372326 | J:329059
 
First Author: Du C
Year: 2022
Journal: Front Cell Dev Biol
Title: Rheb Promotes Triglyceride Secretion and Ameliorates Diet-Induced Steatosis in the Liver.
Volume: 10
Pages: 808140
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Publication
30514904 | J:298778
First Author: Deng L
Year: 2019
Journal: Cell Res
Title: Ubiquitination of Rheb governs growth factor-induced mTORC1 activation.
Volume: 29
Issue: 2
Pages: 136-150
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Publication
- | J:70528
   
First Author: Watanabe S
Year: 2000
Journal: GenBank Submission
Title: Mus musculus rheb mRNA for Ras homolog, complete cds
Pages: AB039919
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Publication
27960107 | J:239839
 
First Author: Shahani N
Year: 2017
Journal: Neurobiol Aging
Title: Forebrain depletion of Rheb GTPase elicits spatial memory deficits in mice.
Volume: 50
Pages: 134-143
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Publication
31220300 | J:294498
First Author: Meng W
Year: 2019
Journal: J Mol Cell Biol
Title: Rheb promotes brown fat thermogenesis by Notch-dependent activation of the PKA signaling pathway.
Volume: 11
Issue: 9
Pages: 781-790
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Publication
16631613 | J:338254
First Author: Buerger C
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Localization of Rheb to the endomembrane is critical for its signaling function.
Volume: 344
Issue: 3
Pages: 869-80
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Publication
29222112 | J:257623
 
First Author: Hao F
Year: 2018
Journal: J Cell Sci
Title: Rheb localized on the Golgi membrane activates lysosome-localized mTORC1 at the Golgi-lysosome contact site.
Volume: 131
Issue: 3
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Publication
28242620 | J:246940
First Author: Meng W
Year: 2017
Journal: Diabetes
Title: Rheb Inhibits Beiging of White Adipose Tissue via PDE4D5-Dependent Downregulation of the cAMP-PKA Signaling Pathway.
Volume: 66
Issue: 5
Pages: 1198-1213
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Publication
24713393 | J:213136
First Author: Baker MD
Year: 2014
Journal: Reproduction
Title: The small GTPase Rheb is required for spermatogenesis but not oogenesis.
Volume: 147
Issue: 5
Pages: 615-25
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Publication
25880340 | J:222712
 
First Author: Sugiura H
Year: 2015
Journal: Nat Commun
Title: Rheb activation disrupts spine synapse formation through accumulation of syntenin in tuberous sclerosis complex.
Volume: 6
Pages: 6842
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Publication
37463107 | J:345123
First Author: Huang H
Year: 2023
Journal: Cell Rep
Title: Disruption of neuronal RHEB signaling impairs oligodendrocyte differentiation and myelination through mTORC1-DLK1 axis.
Volume: 42
Issue: 7
Pages: 112801
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Publication
22294621 | J:196624
First Author: Sciarretta S
Year: 2012
Journal: Circulation
Title: Rheb is a critical regulator of autophagy during myocardial ischemia: pathophysiological implications in obesity and metabolic syndrome.
Volume: 125
Issue: 9
Pages: 1134-46
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Publication
29175333 | J:272444
First Author: Peng H
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Distinct roles of Rheb and Raptor in activating mTOR complex 1 for the self-renewal of hematopoietic stem cells.
Volume: 495
Issue: 1
Pages: 1129-1135
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31315433 | J:327125
First Author: Zhang Q
Year: 2019
Journal: Arterioscler Thromb Vasc Biol
Title: Rheb (Ras Homolog Enriched in Brain 1) Deficiency in Mature Macrophages Prevents Atherosclerosis by Repressing Macrophage Proliferation, Inflammation, and Lipid Uptake.
Volume: 39
Issue: 9
Pages: 1787-1801
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20388784 | J:158945
First Author: Lu ZH
Year: 2010
Journal: Cancer Res
Title: Mammalian target of rapamycin activator RHEB is frequently overexpressed in human carcinomas and is critical and sufficient for skin epithelial carcinogenesis.
Volume: 70
Issue: 8
Pages: 3287-98
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17942919 | J:125965
First Author: Finlay GA
Year: 2007
Journal: Cancer Res
Title: Selective inhibition of growth of tuberous sclerosis complex 2 null cells by atorvastatin is associated with impaired Rheb and Rho GTPase function and reduced mTOR/S6 kinase activity.
Volume: 67
Issue: 20
Pages: 9878-86
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23426372 | J:197831
First Author: Tamai T
Year: 2013
Journal: J Biol Chem
Title: Rheb (Ras homologue enriched in brain)-dependent mammalian target of rapamycin complex 1 (mTORC1) activation becomes indispensable for cardiac hypertrophic growth after early postnatal period.
Volume: 288
Issue: 14
Pages: 10176-87
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32920594 | J:340198
First Author: Ma X
Year: 2020
Journal: Cell Death Dis
Title: Persistent Rheb-induced mTORC1 activation in spinal cord neurons induces hypersensitivity in neuropathic pain.
Volume: 11
Issue: 9
Pages: 747
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Publication
21896734 | J:176586
First Author: Banerjee S
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Neurofibromatosis-1 regulates mTOR-mediated astrocyte growth and glioma formation in a TSC/Rheb-independent manner.
Volume: 108
Issue: 38
Pages: 15996-6001
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Publication
34619097 | J:314132
First Author: Jia L
Year: 2021
Journal: Dev Cell
Title: Rheb-regulated mitochondrial pyruvate metabolism of Schwann cells linked to axon stability.
Volume: 56
Issue: 21
Pages: 2980-2994.e6
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Publication
24303063 | J:209763
First Author: Groenewoud MJ
Year: 2013
Journal: PLoS One
Title: Mammalian target of rapamycin complex I (mTORC1) activity in ras homologue enriched in brain (Rheb)-deficient mouse embryonic fibroblasts.
Volume: 8
Issue: 11
Pages: e81649
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24130493 | J:246768
First Author: Wang J
Year: 2013
Journal: PLoS Pathog
Title: MicroRNA-155 promotes autophagy to eliminate intracellular mycobacteria by targeting Rheb.
Volume: 9
Issue: 10
Pages: e1003697
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30262562 | J:295707
First Author: Wang X
Year: 2019
Journal: Haematologica
Title: Rheb1 loss leads to increased hematopoietic stem cell proliferation and myeloid-biased differentiation in vivo.
Volume: 104
Issue: 2
Pages: 245-255
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12820960 | J:338163
First Author: Garami A
Year: 2003
Journal: Mol Cell
Title: Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2.
Volume: 11
Issue: 6
Pages: 1457-66
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21513702 | J:172202
First Author: Sasaki H
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Acceleration of autoimmune diabetes in Rheb-congenic NOD mice with β-cell-specific mTORC1 activation.
Volume: 408
Issue: 2
Pages: 306-11
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18650380 | J:139022
First Author: Schewe DM
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: ATF6alpha-Rheb-mTOR signaling promotes survival of dormant tumor cells in vivo.
Volume: 105
Issue: 30
Pages: 10519-24
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19258434 | J:154349
First Author: Hamada S
Year: 2009
Journal: Diabetes
Title: Upregulation of the mammalian target of rapamycin complex 1 pathway by Ras homolog enriched in brain in pancreatic beta-cells leads to increased beta-cell mass and prevention of hyperglycemia.
Volume: 58
Issue: 6
Pages: 1321-32
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Publication
28225024 | J:271919
 
First Author: Li K
Year: 2017
Journal: Sci Rep
Title: Rheb1 deletion in myeloid cells aggravates OVA-induced allergic inflammation in mice.
Volume: 7
Pages: 42655
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19451232 | J:150143
First Author: Lee MN
Year: 2009
Journal: Mol Cell Biol
Title: Glycolytic flux signals to mTOR through glyceraldehyde-3-phosphate dehydrogenase-mediated regulation of Rheb.
Volume: 29
Issue: 14
Pages: 3991-4001
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28945203 | J:255466
First Author: Asrani K
Year: 2017
Journal: J Clin Invest
Title: mTORC1 loss impairs epidermal adhesion via TGF-β/Rho kinase activation.
Volume: 127
Issue: 11
Pages: 4001-4017
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Publication
29961810 | J:268375
First Author: Xiong Z
Year: 2018
Journal: Biol Reprod
Title: Raptor directs Sertoli cell cytoskeletal organization and polarity in the mouse testis.
Volume: 99
Issue: 6
Pages: 1289-1302
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26026060 | J:325030
First Author: Guan Y
Year: 2015
Journal: J Immunol
Title: Repression of Mammalian Target of Rapamycin Complex 1 Inhibits Intestinal Regeneration in Acute Inflammatory Bowel Disease Models.
Volume: 195
Issue: 1
Pages: 339-46
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Publication
24648513 | -
First Author: Mazhab-Jafari MT
Year: 2014
Journal: J Biol Chem
Title: Structure-guided mutation of the conserved G3-box glycine in Rheb generates a constitutively activated regulator of mammalian target of rapamycin (mTOR).
Volume: 289
Issue: 18
Pages: 12195-201
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Publication
28424242 | J:247857
First Author: Chornoguz O
Year: 2017
Journal: J Immunol
Title: mTORC1 Promotes T-bet Phosphorylation To Regulate Th1 Differentiation.
Volume: 198
Issue: 10
Pages: 3939-3948
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28289099 | J:242501
First Author: Jacobs BL
Year: 2017
Journal: J Biol Chem
Title: Identification of mechanically regulated phosphorylation sites on tuberin (TSC2) that control mechanistic target of rapamycin (mTOR) signaling.
Volume: 292
Issue: 17
Pages: 6987-6997
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Publication
27374985 | J:253765
 
First Author: Diao F
Year: 2016
Journal: Sci Rep
Title: Alteration of protein prenylation promotes spermatogonial differentiation and exhausts spermatogonial stem cells in newborn mice.
Volume: 6
Pages: 28917
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30582446 | J:292335
First Author: Blackwood EA
Year: 2019
Journal: Circ Res
Title: ATF6 Regulates Cardiac Hypertrophy by Transcriptional Induction of the mTORC1 Activator, Rheb.
Volume: 124
Issue: 1
Pages: 79-93
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24282297 | J:205513
First Author: Wang Y
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Tuberous sclerosis 1 (Tsc1)-dependent metabolic checkpoint controls development of dendritic cells.
Volume: 110
Issue: 50
Pages: E4894-903
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20668162 | J:182841
First Author: Goodman CA
Year: 2010
Journal: Mol Biol Cell
Title: A phosphatidylinositol 3-kinase/protein kinase B-independent activation of mammalian target of rapamycin signaling is sufficient to induce skeletal muscle hypertrophy.
Volume: 21
Issue: 18
Pages: 3258-68
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21238928 | J:168571
First Author: Zou J
Year: 2011
Journal: Dev Cell
Title: Rheb1 is required for mTORC1 and myelination in postnatal brain development.
Volume: 20
Issue: 1
Pages: 97-108
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25759467 | J:221351
First Author: Goorden SM
Year: 2015
Journal: Hum Mol Genet
Title: Intact neuronal function in Rheb1 mutant mice: implications for TORC1-based treatments.
Volume: 24
Issue: 12
Pages: 3390-8
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28891034 | J:254122
First Author: Tian Q
Year: 2017
Journal: Geroscience
Title: RHEB1 insufficiency in aged male mice is associated with stress-induced seizures.
Volume: 39
Issue: 5-6
Pages: 557-570
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26708151 | J:236764
First Author: Tian Q
Year: 2016
Journal: Histochem Cell Biol
Title: RHEB1 expression in embryonic and postnatal mouse.
Volume: 145
Issue: 5
Pages: 561-72
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35372343 | J:323345
 
First Author: Li M
Year: 2022
Journal: Front Cell Dev Biol
Title: Rapamycin Promotes the Expansion of Myeloid Cells by Increasing G-CSF Expression in Mesenchymal Stem Cells.
Volume: 10
Pages: 779159
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23567640 | J:198530
First Author: Wu X
Year: 2013
Journal: Am J Pathol
Title: Genetic and pharmacological inhibition of Rheb1-mTORC1 signaling exerts cardioprotection against adverse cardiac remodeling in mice.
Volume: 182
Issue: 6
Pages: 2005-14
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19690340 | J:153842
First Author: Campbell TB
Year: 2009
Journal: Blood
Title: Overexpression of Rheb2 enhances mouse hematopoietic progenitor cell growth while impairing stem cell repopulation.
Volume: 114
Issue: 16
Pages: 3392-401
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28701795 | J:253045
First Author: Zou Y
Year: 2017
Journal: Sci Rep
Title: Terahertz Spectroscopic Diagnosis of Myelin Deficit Brain in Mice and Rhesus Monkey with Chemometric Techniques.
Volume: 7
Issue: 1
Pages: 5176
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27163399 | J:235865
First Author: Wang X
Year: 2016
Journal: Exp Cell Res
Title: Rheb1-mTORC1 maintains macrophage differentiation and phagocytosis in mice.
Volume: 344
Issue: 2
Pages: 219-28
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34124040 | J:312764
 
First Author: Gao J
Year: 2021
Journal: Front Cell Dev Biol
Title: Rheb1-Deficient Neutrophils Promote Hematopoietic Stem/Progenitor Cell Proliferation via Mesenchymal Stem Cells.
Volume: 9
Pages: 650599
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19538929 | J:150108
First Author: Delgoffe GM
Year: 2009
Journal: Immunity
Title: The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment.
Volume: 30
Issue: 6
Pages: 832-44
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31353861 | J:346642
First Author: Koene LMC
Year: 2019
Journal: Ann Clin Transl Neurol
Title: Effects of antiepileptic drugs in a new TSC/mTOR-dependent epilepsy mouse model.
Volume: 6
Issue: 7
Pages: 1273-1291
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23027611 | J:215861
First Author: Meffre J
Year: 2012
Journal: EMBO Mol Med
Title: 5-HT(6) receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia.
Volume: 4
Issue: 10
Pages: 1043-56
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25893604 | J:222700
First Author: Pollizzi KN
Year: 2015
Journal: J Clin Invest
Title: mTORC1 and mTORC2 selectively regulate CD8⁺ T cell differentiation.
Volume: 125
Issue: 5
Pages: 2090-108
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21358638 | J:170683
First Author: Delgoffe GM
Year: 2011
Journal: Nat Immunol
Title: The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2.
Volume: 12
Issue: 4
Pages: 295-303
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32348753 | J:306412
First Author: Xiao B
Year: 2020
Journal: Cell Rep
Title: Rheb1-Independent Activation of mTORC1 in Mammary Tumors Occurs through Activating Mutations in mTOR.
Volume: 31
Issue: 4
Pages: 107571
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32567735 | J:314886
First Author: Dumas AA
Year: 2020
Journal: EMBO J
Title: Microglia promote glioblastoma via mTOR-mediated immunosuppression of the tumour microenvironment.
Volume: 39
Issue: 15
Pages: e103790
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27064374 | J:260621
First Author: Pollizzi KN
Year: 2016
Journal: Nat Immunol
Title: Asymmetric inheritance of mTORC1 kinase activity during division dictates CD8(+) T cell differentiation.
Volume: 17
Issue: 6
Pages: 704-11
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27063844 | J:236897
 
First Author: Fansa EK
Year: 2016
Journal: Nat Commun
Title: PDE6δ-mediated sorting of INPP5E into the cilium is determined by cargo-carrier affinity.
Volume: 7
Pages: 11366
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35011720 | J:317408
 
First Author: Grad M
Year: 2022
Journal: Cells
Title: Altered White Matter and microRNA Expression in a Murine Model Related to Williams Syndrome Suggests That miR-34b/c Affects Brain Development via Ptpru and Dcx Modulation.
Volume: 11
Issue: 1
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25411504 | J:217386
First Author: Zou Y
Year: 2014
Journal: J Neurosci
Title: Oligodendrocyte precursor cell-intrinsic effect of Rheb1 controls differentiation and mediates mTORC1-dependent myelination in brain.
Volume: 34
Issue: 47
Pages: 15764-78
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33941648 | J:317400
First Author: Liu Y
Year: 2021
Journal: J Neurosci
Title: GPR84 Is Essential for the Taste of Medium Chain Saturated Fatty Acids.
Volume: 41
Issue: 24
Pages: 5219-5228
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35022234 | J:320720
 
First Author: Yu Z
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: GATOR2 complex-mediated amino acid signaling regulates brain myelination.
Volume: 119
Issue: 3
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11555636 | J:71817
First Author: Sutherland HG
Year: 2001
Journal: Hum Mol Genet
Title: Large-scale identification of mammalian proteins localized to nuclear sub-compartments.
Volume: 10
Issue: 18
Pages: 1995-2011
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37812701 | J:342544
First Author: Radzishevsky I
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Impairment of serine transport across the blood-brain barrier by deletion of Slc38a5 causes developmental delay and motor dysfunction.
Volume: 120
Issue: 42
Pages: e2302780120
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25211037 | J:263419
First Author: Distler U
Year: 2014
Journal: Proteomics
Title: In-depth protein profiling of the postsynaptic density from mouse hippocampus using data-independent acquisition proteomics.
Volume: 14
Issue: 21-22
Pages: 2607-13
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- | J:29505
     
First Author: Copeland NG
Year: 1999
Journal: Database Release
Title: Copeland-Jenkins (Frederick) Interspecific Backcross Mapping Data
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29688375 | J:250512
   
First Author: Li J
Year: 2018
Journal: Database (Oxford)
Title: CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice.
Volume: 2018
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16537572 | J:108241
First Author: Desai J
Year: 2006
Journal: Hum Mol Genet
Title: Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.
Volume: 15
Issue: 8
Pages: 1329-41
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- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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15741177 | J:126097
First Author: Cobellis G
Year: 2005
Journal: Nucleic Acids Res
Title: Tagging genes with cassette-exchange sites.
Volume: 33
Issue: 4
Pages: e44
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- | J:94338
     
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
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12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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- | J:342605
       
First Author: GOA curators
Year: 2016
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First Author: The Gene Ontology Consortium
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Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
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First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
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Journal: Nature
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Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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First Author: The Gene Ontology Consortium
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Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Year: 2010
Title: Annotation inferences using phylogenetic trees
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