Type |
Details |
Score |
Publication |
First Author: |
Liu J |
Year: |
2019 |
Journal: |
Nat Commun |
Title: |
JNK1/2 represses Lkb1-deficiency-induced lung squamous cell carcinoma progression. |
Volume: |
10 |
Issue: |
1 |
Pages: |
2148 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim SJ |
Year: |
2022 |
Journal: |
Nature |
Title: |
Kinase signalling in excitatory neurons regulates sleep quantity and depth. |
Volume: |
612 |
Issue: |
7940 |
Pages: |
512-518 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ulisse V |
Year: |
2020 |
Journal: |
Life Sci Alliance |
Title: |
Regulation of axonal morphogenesis by the mitochondrial protein Efhd1. |
Volume: |
3 |
Issue: |
7 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Shaw RJ |
Year: |
2004 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress. |
Volume: |
101 |
Issue: |
10 |
Pages: |
3329-35 |
|
•
•
•
•
•
|
Publication |
First Author: |
Just PA |
Year: |
2015 |
Journal: |
PLoS One |
Title: |
LKB1 and Notch Pathways Interact and Control Biliary Morphogenesis. |
Volume: |
10 |
Issue: |
12 |
Pages: |
e0145400 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kobayashi T |
Year: |
2015 |
Journal: |
Nat Rev Cancer |
Title: |
Modelling bladder cancer in mice: opportunities and challenges. |
Volume: |
15 |
Issue: |
1 |
Pages: |
42-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lai LP |
Year: |
2013 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Lkb1/Stk11 regulation of mTOR signaling controls the transition of chondrocyte fates and suppresses skeletal tumor formation. |
Volume: |
110 |
Issue: |
48 |
Pages: |
19450-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Morgan-Smith M |
Year: |
2014 |
Journal: |
Elife |
Title: |
GSK-3 signaling in developing cortical neurons is essential for radial migration and dendritic orientation. |
Volume: |
3 |
|
Pages: |
e02663 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lilley BN |
Year: |
2013 |
Journal: |
Neuron |
Title: |
SAD kinases sculpt axonal arbors of sensory neurons through long- and short-term responses to neurotrophin signals. |
Volume: |
79 |
Issue: |
1 |
Pages: |
39-53 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hezel AF |
Year: |
2008 |
Journal: |
Mol Cell Biol |
Title: |
Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms. |
Volume: |
28 |
Issue: |
7 |
Pages: |
2414-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gao N |
Year: |
2010 |
Journal: |
Genes Dev |
Title: |
Cdx2 regulates endo-lysosomal function and epithelial cell polarity. |
Volume: |
24 |
Issue: |
12 |
Pages: |
1295-305 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim GE |
Year: |
2015 |
Journal: |
Cardiovasc Res |
Title: |
LKB1 deletion causes early changes in atrial channel expression and electrophysiology prior to atrial fibrillation. |
Volume: |
108 |
Issue: |
1 |
Pages: |
197-208 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li G |
Year: |
2017 |
Journal: |
Cell Death Dis |
Title: |
Deletion of Pdcd5 in mice led to the deficiency of placenta development and embryonic lethality. |
Volume: |
8 |
Issue: |
5 |
Pages: |
e2811 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Li J |
Year: |
2018 |
Journal: |
Database (Oxford) |
Title: |
CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice. |
Volume: |
2018 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
University of California, Davis |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by the University of California, Davis |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GO Central curators, GOA curators, Rhea curators |
Year: |
2020 |
|
Title: |
Automatic Gene Ontology annotation based on Rhea mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2001 |
|
Title: |
Gene Ontology Annotation by the MGI Curatorial Staff |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen J |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. |
Volume: |
100 |
Issue: |
17 |
Pages: |
9918-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stryke D |
Year: |
2003 |
Journal: |
Nucleic Acids Res |
Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
Volume: |
31 |
Issue: |
1 |
Pages: |
278-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bedogni F |
Year: |
2021 |
Journal: |
Front Mol Neurosci |
Title: |
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. |
Volume: |
14 |
|
Pages: |
686034 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Helmholtz Zentrum Muenchen GmbH |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Ishqi HM |
Year: |
2018 |
Journal: |
Gene |
Title: |
Differentially expressed novel alternatively spliced transcript variant of tumor suppressor Stk11 gene in mouse. |
Volume: |
668 |
|
Pages: |
146-154 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
436
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
412
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
232
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
164
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
310
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
55
|
Fragment?: |
false |
|
•
•
•
•
•
|
Allele |
Name: |
serine/threonine kinase 11; targeted mutation 1.2, Ronald DePinho |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Stk11/Stk11<+> |
Background: |
involves: 129S6/SvEvTac * C57BL/6 * FVB/N * SJL |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
698
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Shelly M |
Year: |
2007 |
Journal: |
Cell |
Title: |
LKB1/STRAD promotes axon initiation during neuronal polarization. |
Volume: |
129 |
Issue: |
3 |
Pages: |
565-77 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sherman MH |
Year: |
2010 |
Journal: |
Mol Cell |
Title: |
AID-induced genotoxic stress promotes B cell differentiation in the germinal center via ATM and LKB1 signaling. |
Volume: |
39 |
Issue: |
6 |
Pages: |
873-85 |
|
•
•
•
•
•
|
Allele |
Name: |
serine/threonine kinase 11; targeted mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Stk11/Stk11<+> |
Background: |
involves: 129S6/SvEvTac * FVB/N |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Stk11/Stk11<+> |
Background: |
involves: 129S6/SvEvTac * C57BL/6 * CD-1 * FVB/N * SJL |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Stk11/Stk11 |
Background: |
involves: 129S6/SvEvTac |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Stk11/Stk11 |
Background: |
involves: 129S6/SvEvTac * C57BL/6 * FVB/N * SJL |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Kras/Kras<+> Stk11/Stk11 |
Background: |
involves: 129S4/SvJae * 129S6/SvEvTac |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Kras/Kras<+> Stk11/Stk11 |
Background: |
involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * FVB/N |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Stk11/Stk11 |
Background: |
involves: 129S6/SvEvTac * C57BL/6 * FVB/N |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Strain |
Attribute String: |
congenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
Allele |
Name: |
serine/threonine kinase 11; targeted mutation 1.1, Kou-ichi Jishage |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
serine/threonine kinase 11; targeted mutation 1, Tomi P Makela |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
serine/threonine kinase 11; targeted mutation 1, Ronald DePinho |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
Allele |
Name: |
serine/threonine kinase 11; targeted mutation 1.1, Marsha L Frazier |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
serine/threonine kinase 11; targeted mutation 1.1, Ronald DePinho |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Stk11/Stk11<+> |
Background: |
involves: 129S7/SvEvBrd * C57BL/6J |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Stk11/Stk11<+> |
Background: |
involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Stk11/Stk11<+> Trp53/Trp53<+> |
Background: |
involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Stk11/Stk11<+> |
Background: |
Not Specified |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Stk11/Stk11<+> |
Background: |
involves: 129S7/SvEvBrd * C57BL/6 * CD-1 |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Stk11/Stk11 Tg(Pdx1-cre)89.1Dam/? |
Background: |
involves: 129S6/SvEvTac * C57BL/6 * CBA * FVB/N * ICR |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Stk11/Stk11 Tg(KRT14-cre)1Ipc/? |
Background: |
involves: 129S6/SvEvTac * C57BL/6 * FVB/N * SJL |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Amhr2/Amhr2<+> Stk11/Stk11 |
Background: |
involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang Y |
Year: |
2017 |
Journal: |
Cancer Cell |
Title: |
A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations. |
Volume: |
31 |
Issue: |
6 |
Pages: |
820-832.e3 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kullmann L |
Year: |
2018 |
Journal: |
Oncogene |
Title: |
Controlling the master-upstream regulation of the tumor suppressor LKB1. |
Volume: |
37 |
Issue: |
23 |
Pages: |
3045-3057 |
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•
•
•
•
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Publication |
First Author: |
Mukhopadhyay S |
Year: |
2023 |
Journal: |
Cancer Res |
Title: |
Genome-Wide CRISPR Screens Identify Multiple Synthetic Lethal Targets That Enhance KRASG12C Inhibitor Efficacy. |
Volume: |
83 |
Issue: |
24 |
Pages: |
4095-4111 |
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•
•
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•
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Publication |
First Author: |
Ballif BA |
Year: |
2004 |
Journal: |
Mol Cell Proteomics |
Title: |
Phosphoproteomic analysis of the developing mouse brain. |
Volume: |
3 |
Issue: |
11 |
Pages: |
1093-101 |
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•
•
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Publication |
First Author: |
Trost M |
Year: |
2009 |
Journal: |
Immunity |
Title: |
The phagosomal proteome in interferon-gamma-activated macrophages. |
Volume: |
30 |
Issue: |
1 |
Pages: |
143-54 |
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Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
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•
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Publication |
First Author: |
Huttlin EL |
Year: |
2010 |
Journal: |
Cell |
Title: |
A tissue-specific atlas of mouse protein phosphorylation and expression. |
Volume: |
143 |
Issue: |
7 |
Pages: |
1174-89 |
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Publication |
First Author: |
Church DM |
Year: |
2009 |
Journal: |
PLoS Biol |
Title: |
Lineage-specific biology revealed by a finished genome assembly of the mouse. |
Volume: |
7 |
Issue: |
5 |
Pages: |
e1000112 |
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