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Search results 101 to 200 out of 309 for Zap70

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Type Details Score
GXD Expression
GXD Expression
     
Probe: MGI:5013617
Assay Type: Northern blot
Annotation Date: 2011-07-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5013619
Age: postnatal month 3
Specimen Label: Adult kidney
Detected: false
Specimen Num: 9
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•
GXD Expression
GXD Expression
     
Probe: MGI:5013617
Assay Type: Northern blot
Annotation Date: 2011-07-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876826
Stage: TS26
Assay Id: MGI:5013632
Age: embryonic day 18.0
Specimen Label: 18d
Detected: true
Specimen Num: 1
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•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5013617
Assay Type: Northern blot
Annotation Date: 2011-07-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876827
Stage: TS27
Assay Id: MGI:5013632
Age: postnatal newborn
Specimen Label: NB
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5013617
Assay Type: Northern blot
Annotation Date: 2011-07-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:5013632
Age: postnatal week 1
Specimen Label: 1 w
Detected: true
Specimen Num: 3
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•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5013617
Assay Type: Northern blot
Annotation Date: 2011-07-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:5013632
Age: postnatal week 3
Specimen Label: 3 w
Detected: true
Specimen Num: 4
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•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5013617
Assay Type: Northern blot
Annotation Date: 2011-07-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:5013632
Age: postnatal month 3
Specimen Label: 3 m
Detected: true
Specimen Num: 5
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•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5013617
Assay Type: Northern blot
Annotation Date: 2011-07-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:5013632
Age: postnatal month 12
Specimen Label: 12 m
Detected: true
Specimen Num: 6
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•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7550458
Assay Type: RT-PCR
Annotation Date: 2023-11-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684624
Stage: TS24
Assay Id: MGI:7550469
Age: embryonic day 16.5
Specimen Label: WT
Detected: true
Specimen Num: 1
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•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7550458
Assay Type: RT-PCR
Annotation Date: 2023-11-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684624
Stage: TS24
Assay Id: MGI:7550469
Age: embryonic day 16.5
Specimen Label: KO
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
   
Probe: MGI:5013633
Assay Type: RNA in situ
Annotation Date: 2011-07-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5013634
Age: postnatal
Specimen Label: 5a
Detected: true
Specimen Num: 4
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•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5013633
Assay Type: RNA in situ
Annotation Date: 2011-07-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1756328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5013634
Age: postnatal
Specimen Label: 5b
Detected: true
Specimen Num: 5
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•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5013633
Assay Type: RNA in situ
Annotation Date: 2011-07-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3522328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5013634
Age: postnatal
Specimen Label: 5c
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5013633
Assay Type: RNA in situ
Annotation Date: 2011-07-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5013634
Age: embryonic day 15.0
Specimen Label: 6a
Detected: true
Specimen Num: 7
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5013633
Assay Type: RNA in situ
Annotation Date: 2011-07-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:5013634
Age: embryonic day 15.0
Note: Expression is in epithelia of the bronchi.
Specimen Label: 6c
Detected: true
Specimen Num: 8
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•
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•
GXD Expression
GXD Expression
 
Probe: MGI:5013633
Assay Type: RNA in situ
Annotation Date: 2011-07-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:5013634
Age: embryonic day 15.0
Note: Expression is in the hematopoietic cells in the liver.
Specimen Label: 6e
Detected: true
Specimen Num: 9
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•
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•
GXD Expression
GXD Expression
   
Probe: MGI:5013633
Assay Type: RNA in situ
Annotation Date: 2011-07-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287323
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5013634
Age: embryonic day 15.0
Specimen Label: 6g
Detected: true
Specimen Num: 10
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5013633
Assay Type: RNA in situ
Annotation Date: 2011-07-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876827
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:5013634
Age: postnatal newborn
Note: Expression is in immature thymocytes in the subcapsular layer.
Specimen Label: 4a
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
 
Probe: MGI:5013633
Assay Type: RNA in situ
Annotation Date: 2011-07-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1930528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5013634
Age: postnatal month 3
Note: Expression is in mature thymocytes.
Specimen Label: 4c
Detected: true
Specimen Num: 2
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•
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•
GXD Expression
GXD Expression
 
Probe: MGI:5013633
Assay Type: RNA in situ
Annotation Date: 2011-07-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3580428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5013634
Age: postnatal month 3
Note: Expression is in the T-cell dependent area.
Specimen Label: 4d
Detected: true
Specimen Num: 3
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5013633
Assay Type: RNA in situ
Annotation Date: 2011-07-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1930527
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:5013634
Age: postnatal newborn
Note: Expression is in mature thymocytes.
Specimen Label: 4a
Detected: true
Specimen Num: 1
•
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•
•
GXD Expression
GXD Expression
   
Probe: MGI:5013633
Assay Type: RNA in situ
Annotation Date: 2011-07-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3586327
Pattern: Single cells
Stage: TS27
Assay Id: MGI:5013634
Age: postnatal newborn
Specimen Label: 4a
Detected: true
Specimen Num: 1
•
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•
•
GXD Expression
GXD Expression
     
Probe: MGI:5013633
Assay Type: RNA in situ
Annotation Date: 2011-07-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:5013634
Age: postnatal newborn
Specimen Label: Not shown NB
Detected: false
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5013633
Assay Type: RNA in situ
Annotation Date: 2011-07-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684627
Stage: TS27
Assay Id: MGI:5013634
Age: postnatal newborn
Specimen Label: Not shown NB
Detected: false
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5013633
Assay Type: RNA in situ
Annotation Date: 2011-07-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3287427
Stage: TS27
Assay Id: MGI:5013634
Age: postnatal newborn
Specimen Label: Not shown NB
Detected: false
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5013633
Assay Type: RNA in situ
Annotation Date: 2011-07-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5013634
Age: embryonic day 15.0
Specimen Label: Not shown E15
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5013633
Assay Type: RNA in situ
Annotation Date: 2011-07-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:5013634
Age: postnatal adult
Specimen Label: Not shown Adult
Detected: false
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5013633
Assay Type: RNA in situ
Annotation Date: 2011-07-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5013634
Age: postnatal adult
Specimen Label: Not shown Adult
Detected: false
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5013633
Assay Type: RNA in situ
Annotation Date: 2011-07-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3287428
Stage: TS28
Assay Id: MGI:5013634
Age: postnatal adult
Specimen Label: Not shown Adult
Detected: false
Specimen Num: 13
•
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•
Publication
31641113 | J:281521
First Author: Thaker YR
Year: 2019
Journal: Nat Commun
Title: GTPase-activating protein Rasal1 associates with ZAP-70 of the TCR and negatively regulates T-cell tumor immunity.
Volume: 10
Issue: 1
Pages: 4804
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Publication
7553892 | J:29096
First Author: Ishijima SA
Year: 1995
Journal: Cell Immunol
Title: Expression of ZAP-70 gene in the developing thymus and various nonlymphoid tissues of embryonic and adult mice.
Volume: 165
Issue: 2
Pages: 278-83
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Publication
11567635 | J:71804
First Author: Sosinowski T
Year: 2001
Journal: Immunity
Title: The Src-like adaptor protein downregulates the T cell receptor on CD4+CD8+ thymocytes and regulates positive selection.
Volume: 15
Issue: 3
Pages: 457-66
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Publication
17606633 | J:125879
First Author: Palacios EH
Year: 2007
Journal: J Exp Med
Title: Distinct roles for Syk and ZAP-70 during early thymocyte development.
Volume: 204
Issue: 7
Pages: 1703-15
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Publication
18209059 | J:131507
First Author: Posevitz V
Year: 2008
Journal: J Immunol
Title: Regulation of T cell homeostasis by the transmembrane adaptor protein SIT.
Volume: 180
Issue: 3
Pages: 1634-42
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Publication
15750595 | J:97610
First Author: Sun G
Year: 2005
Journal: Nat Immunol
Title: The zinc finger protein cKrox directs CD4 lineage differentiation during intrathymic T cell positive selection.
Volume: 6
Issue: 4
Pages: 373-81
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Publication
27288531 | J:269078
First Author: Sood S
Year: 2016
Journal: J Immunol
Title: Loss of the Protein Tyrosine Phosphatase PTPN22 Reduces Mannan-Induced Autoimmune Arthritis in SKG Mice.
Volume: 197
Issue: 2
Pages: 429-40
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Publication
30150283 | J:265220
First Author: Napier RJ
Year: 2018
Journal: J Immunol
Title: Nod2 Deficiency Augments Th17 Responses and Exacerbates Autoimmune Arthritis.
Volume: 201
Issue: 7
Pages: 1889-1898
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Publication
11514605 | J:71099
First Author: Magnan A
Year: 2001
Journal: J Exp Med
Title: T cell development and T cell responses in mice with mutations affecting tyrosines 292 or 315 of the ZAP-70 protein tyrosine kinase.
Volume: 194
Issue: 4
Pages: 491-505
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Publication
11836527 | J:74994
First Author: Colucci F
Year: 2002
Journal: Nat Immunol
Title: Natural cytotoxicity uncoupled from the Syk and ZAP-70 intracellular kinases.
Volume: 3
Issue: 3
Pages: 288-94
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Publication
16027224 | J:100141
First Author: Myers MD
Year: 2005
Journal: J Cell Biol
Title: Src-like adaptor protein down-regulates T cell receptor (TCR)-CD3 expression by targeting TCRzeta for degradation.
Volume: 170
Issue: 2
Pages: 285-94
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Publication
9275205 | J:42818
First Author: Cheng AM
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: The Syk and ZAP-70 SH2-containing tyrosine kinases are implicated in pre-T cell receptor signaling.
Volume: 94
Issue: 18
Pages: 9797-801
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Publication
15365098 | J:93941
First Author: Yu Q
Year: 2004
Journal: J Exp Med
Title: IL-7 receptor signals inhibit expression of transcription factors TCF-1, LEF-1, and RORgammat: impact on thymocyte development.
Volume: 200
Issue: 6
Pages: 797-803
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Publication
28664612 | J:246254
First Author: Rothe K
Year: 2017
Journal: Eur J Immunol
Title: Autoimmune arthritis induces paired immunoglobulin-like receptor B expression on CD4+ T cells from SKG mice.
Volume: 47
Issue: 9
Pages: 1457-1467
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Publication
31919358 | J:285893
First Author: Regan-Komito D
Year: 2020
Journal: Nat Commun
Title: GM-CSF drives dysregulated hematopoietic stem cell activity and pathogenic extramedullary myelopoiesis in experimental spondyloarthritis.
Volume: 11
Issue: 1
Pages: 155
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Publication
34669443 | J:324689
First Author: Nakamura A
Year: 2021
Journal: Sci Transl Med
Title: Macrophage migration inhibitory factor drives pathology in a mouse model of spondyloarthritis and is associated with human disease.
Volume: 13
Issue: 616
Pages: eabg1210
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Publication
24498279 | J:212852
First Author: Wu DJ
Year: 2014
Journal: PLoS One
Title: Autoimmunity-associated LYP-W620 does not impair thymic negative selection of autoreactive T cells.
Volume: 9
Issue: 2
Pages: e86677
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Publication
21895656 | J:346501
First Author: Angibaud J
Year: 2011
Journal: J Neurochem
Title: The immune molecule CD3zeta and its downstream effectors ZAP-70/Syk mediate ephrin signaling in neurons to regulate early neuritogenesis.
Volume: 119
Issue: 4
Pages: 708-22
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Publication
10689303 | J:60907
First Author: Turner M
Year: 2000
Journal: Immunol Today
Title: Tyrosine kinase SYK: essential functions for immunoreceptor signalling.
Volume: 21
Issue: 3
Pages: 148-54
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Publication
10781838 | J:62319
First Author: Ulivieri C
Year: 2000
Journal: Mol Immunol
Title: Restoration of thymic development in an Lck(-/-) thymoma overexpressing ZAP-70.
Volume: 37
Issue: 1-2
Pages: 85-90
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Publication
8082894 | J:20601
First Author: Ku G
Year: 1994
Journal: Immunogenetics
Title: Chromosomal location of the Syk and ZAP-70 tyrosine kinase genes in mice and humans.
Volume: 40
Issue: 4
Pages: 300-2
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Publication
9878110 | J:51678
First Author: Garcia GG
Year: 1998
Journal: Cell Immunol
Title: Increased Zap-70 association with CD3zeta in CD4 T cells from old mice.
Volume: 190
Issue: 2
Pages: 91-100
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Publication
14734724 | J:87653
First Author: Zhong L
Year: 2004
Journal: J Immunol
Title: Zeta-associated protein of 70 kDa (ZAP-70), but not Syk, tyrosine kinase can mediate apoptosis of T cells through the Fas/Fas ligand, caspase-8 and caspase-3 pathways.
Volume: 172
Issue: 3
Pages: 1472-82
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Publication
22761313 | J:185495
First Author: Arnold CN
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: A forward genetic screen reveals roles for Nfkbid, Zeb1, and Ruvbl2 in humoral immunity.
Volume: 109
Issue: 31
Pages: 12286-93
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Publication
15143214 | J:90684
First Author: Ohtsuka M
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: NFAM1, an immunoreceptor tyrosine-based activation motif-bearing molecule that regulates B cell development and signaling.
Volume: 101
Issue: 21
Pages: 8126-31
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Publication
11891219 | J:76854
First Author: Pandey A
Year: 2002
Journal: J Biol Chem
Title: A novel Src homology 2 domain-containing molecule, Src-like adapter protein-2 (SLAP-2), which negatively regulates T cell receptor signaling.
Volume: 277
Issue: 21
Pages: 19131-8
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Publication
16327786 | J:112388
First Author: Myers MD
Year: 2006
Journal: Nat Immunol
Title: Src-like adaptor protein regulates TCR expression on thymocytes by linking the ubiquitin ligase c-Cbl to the TCR complex.
Volume: 7
Issue: 1
Pages: 57-66
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Publication
20547827 | J:163409
First Author: Walter JE
Year: 2010
Journal: J Exp Med
Title: Expansion of immunoglobulin-secreting cells and defects in B cell tolerance in Rag-dependent immunodeficiency.
Volume: 207
Issue: 7
Pages: 1541-54
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Publication
18408722 | J:134506
First Author: Mingueneau M
Year: 2008
Journal: Nat Immunol
Title: The proline-rich sequence of CD3epsilon controls T cell antigen receptor expression on and signaling potency in preselection CD4+CD8+ thymocytes.
Volume: 9
Issue: 5
Pages: 522-32
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Publication
14515253 | J:115654
First Author: Lee WH
Year: 2003
Journal: Eur J Immunol
Title: Development of T cells expressing an altered TCR complex.
Volume: 33
Issue: 10
Pages: 2696-705
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Publication
9324357 | J:43156
First Author: Gong Q
Year: 1997
Journal: Immunity
Title: Restoration of thymocyte development and function in zap-70-/- mice by the Syk protein tyrosine kinase.
Volume: 7
Issue: 3
Pages: 369-77
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Publication
17878336 | J:152359
First Author: Wildt KF
Year: 2007
Journal: J Immunol
Title: The transcription factor Zbtb7b promotes CD4 expression by antagonizing Runx-mediated activation of the CD4 silencer.
Volume: 179
Issue: 7
Pages: 4405-14
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Publication
20479941 | J:160836
First Author: Duarte J
Year: 2010
Journal: PLoS One
Title: Modulation of IL-17 and Foxp3 expression in the prevention of autoimmune arthritis in mice.
Volume: 5
Issue: 5
Pages: e10558
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Publication
35058288 | J:333420
First Author: Park J
Year: 2022
Journal: Cancer Immunol Res
Title: The Pellino1-PKCθ Signaling Axis Is an Essential Target for Improving Antitumor CD8+ T-lymphocyte Function.
Volume: 10
Issue: 3
Pages: 327-342
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Publication
26139098 | J:329860
First Author: Alampour-Rajabi S
Year: 2015
Journal: FASEB J
Title: MIF interacts with CXCR7 to promote receptor internalization, ERK1/2 and ZAP-70 signaling, and lymphocyte chemotaxis.
Volume: 29
Issue: 11
Pages: 4497-511
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Publication
8798454 | J:35411
First Author: Latour S
Year: 1996
Journal: J Biol Chem
Title: Differential intrinsic enzymatic activity of Syk and Zap-70 protein-tyrosine kinases.
Volume: 271
Issue: 37
Pages: 22782-90
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Publication
8551236 | J:35635
First Author: Fournel M
Year: 1996
Journal: J Exp Med
Title: Association of tyrosine protein kinase Zap-70 with the protooncogene product p120c-cbl in T lymphocytes.
Volume: 183
Issue: 1
Pages: 301-6
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Publication
12024036 | J:76785
First Author: Loreto MP
Year: 2002
Journal: Mol Cell Biol
Title: Functional cooperation between c-Cbl and Src-like adaptor protein 2 in the negative regulation of T-cell receptor signaling.
Volume: 22
Issue: 12
Pages: 4241-55
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Publication
9182527 | J:41090
First Author: Hatakeyama S
Year: 1997
Journal: J Biol Chem
Title: Subcellular localization and ubiquitin-conjugating enzyme (E2) interactions of mammalian HECT family ubiquitin protein ligases.
Volume: 272
Issue: 24
Pages: 15085-92
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Publication
16501569 | J:112392
First Author: Reiley WW
Year: 2006
Journal: Nat Immunol
Title: Regulation of T cell development by the deubiquitinating enzyme CYLD.
Volume: 7
Issue: 4
Pages: 411-7
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Publication
14738763 | J:89761
First Author: Carpino N
Year: 2004
Journal: Immunity
Title: Regulation of ZAP-70 activation and TCR signaling by two related proteins, Sts-1 and Sts-2.
Volume: 20
Issue: 1
Pages: 37-46
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Publication
21393235 | J:237969
First Author: San Luis B
Year: 2011
Journal: J Biol Chem
Title: Sts-2 is a phosphatase that negatively regulates zeta-associated protein (ZAP)-70 and T cell receptor signaling pathways.
Volume: 286
Issue: 18
Pages: 15943-54
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Publication
24760155 | J:329020
First Author: Klasen C
Year: 2014
Journal: J Immunol
Title: MIF promotes B cell chemotaxis through the receptors CXCR4 and CD74 and ZAP-70 signaling.
Volume: 192
Issue: 11
Pages: 5273-84
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