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Search results 1 to 100 out of 876 for Atr

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Hits by Pathway

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Hits by Category

Type Details Score
Gene
545 | ATR
Type: gene
Organism: human
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Gene
567770 | atr
Type: gene
Organism: zebrafish
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Gene
714443 | ATR
Type: gene
Organism: macaque, rhesus
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Gene
100495593 | atr
Type: gene
Organism: frog, western clawed
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Gene
685055 | Atr
Type: gene
Organism: rat
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Gene
460745 | ATR
Type: gene
Organism: chimpanzee
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Gene
504869 | ATR
Type: gene
Organism: cattle
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Gene
100856315 | ATR
Type: gene
Organism: dog, domestic
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Gene
424777 | ATR
Type: gene
Organism: chicken
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Protein Coding Gene
MGI:108028 | Atr
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
10691732 | J:60768
First Author: Brown EJ
Year: 2000
Journal: Genes Dev
Title: ATR disruption leads to chromosomal fragmentation and early embryonic lethality.
Volume: 14
Issue: 4
Pages: 397-402
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Publication
12629044 | J:83042
First Author: Brown EJ
Year: 2003
Journal: Genes Dev
Title: Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance.
Volume: 17
Issue: 5
Pages: 615-28
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Publication
10801416 | J:61732
First Author: de Klein A
Year: 2000
Journal: Curr Biol
Title: Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice.
Volume: 10
Issue: 8
Pages: 479-82
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Publication
8843195 | J:35913
First Author: Keegan KS
Year: 1996
Journal: Genes Dev
Title: The Atr and Atm protein kinases associate with different sites along meiotically pairing chromosomes.
Volume: 10
Issue: 19
Pages: 2423-37
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Gene
84126 | ATRIP
Type: gene
Organism: human
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Publication
11721054 | J:314777
First Author: Cortez D
Year: 2001
Journal: Science
Title: ATR and ATRIP: partners in checkpoint signaling.
Volume: 294
Issue: 5547
Pages: 1713-6
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Publication
19782648 | J:153964
First Author: O'Driscoll M
Year: 2009
Journal: DNA Repair (Amst)
Title: Mouse models for ATR deficiency.
Volume: 8
Issue: 11
Pages: 1333-7
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Publication
20801936 | J:164024
First Author: Takai H
Year: 2010
Journal: Genes Dev
Title: Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes.
Volume: 24
Issue: 18
Pages: 2019-30
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Publication
23039116 | J:192634
First Author: Kogo H
Year: 2012
Journal: Genes Cells
Title: HORMAD2 is essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity.
Volume: 17
Issue: 11
Pages: 897-912
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Publication
30559436 | J:269157
First Author: Menolfi D
Year: 2018
Journal: Nat Commun
Title: Kinase-dead ATR differs from ATR loss by limiting the dynamic exchange of ATR and RPA.
Volume: 9
Issue: 1
Pages: 5351
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Publication
34210973 | J:326999
First Author: Kirtay M
Year: 2021
Journal: Nat Commun
Title: ATR regulates neuronal activity by modulating presynaptic firing.
Volume: 12
Issue: 1
Pages: 4067
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Publication
29977027 | J:267878
First Author: Pacheco S
Year: 2018
Journal: Nat Commun
Title: ATR is required to complete meiotic recombination in mice.
Volume: 9
Issue: 1
Pages: 2622
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Publication
31489491 | J:307570
First Author: Pacheco S
Year: 2019
Journal: Chromosoma
Title: ATR function is indispensable to allow proper mammalian follicle development.
Volume: 128
Issue: 3
Pages: 489-500
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Publication
23824539 | J:199454
First Author: Royo H
Year: 2013
Journal: Genes Dev
Title: ATR acts stage specifically to regulate multiple aspects of mammalian meiotic silencing.
Volume: 27
Issue: 13
Pages: 1484-94
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Publication
22266795 | J:181920
First Author: Lee Y
Year: 2012
Journal: EMBO J
Title: ATR maintains select progenitors during nervous system development.
Volume: 31
Issue: 5
Pages: 1177-89
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Publication
22078264 | J:316805
First Author: Zhou Z
Year: 2012
Journal: DNA Repair (Amst)
Title: Differential function of NBS1 and ATR in neurogenesis.
Volume: 11
Issue: 2
Pages: 210-21
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Publication
10382071 | J:55411
First Author: Moens PB
Year: 1999
Journal: Chromosoma
Title: The association of ATR protein with mouse meiotic chromosome cores.
Volume: 108
Issue: 2
Pages: 95-102
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Publication
29976923 | J:266323
First Author: Widger A
Year: 2018
Journal: Nat Commun
Title: ATR is a multifunctional regulator of male mouse meiosis.
Volume: 9
Issue: 1
Pages: 2621
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Publication
28123024 | J:239152
First Author: Enriquez-Rios V
Year: 2017
Journal: J Neurosci
Title: DNA-PKcs, ATM, and ATR Interplay Maintains Genome Integrity during Neurogenesis.
Volume: 37
Issue: 4
Pages: 893-905
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Publication
24675793 | J:214145
First Author: Brown AD
Year: 2014
Journal: PLoS One
Title: ATR suppresses endogenous DNA damage and allows completion of homologous recombination repair.
Volume: 9
Issue: 3
Pages: e91222
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Publication
19504344 | J:150723
First Author: Ragland RL
Year: 2009
Journal: Mamm Genome
Title: Mice hypomorphic for Atr have increased DNA damage and abnormal checkpoint response.
Volume: 20
Issue: 6
Pages: 375-85
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Gene
54465 | ETAA1
Type: gene
Organism: human
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Publication
26209650 | J:239795
First Author: Fedoriw AM
Year: 2015
Journal: Development
Title: Key mediators of somatic ATR signaling localize to unpaired chromosomes in spermatocytes.
Volume: 142
Issue: 17
Pages: 2972-80
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Publication
25838540 | J:221585
First Author: Lopez-Contreras AJ
Year: 2015
Journal: Genes Dev
Title: Increased Rrm2 gene dosage reduces fragile site breakage and prolongs survival of ATR mutant mice.
Volume: 29
Issue: 7
Pages: 690-5
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Publication
21826105 | J:184053
First Author: Yu Z
Year: 2012
Journal: Cell Res
Title: The MRE11 GAR motif regulates DNA double-strand break processing and ATR activation.
Volume: 22
Issue: 2
Pages: 305-20
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Publication
32973141 | J:300215
First Author: Kidiyoor GR
Year: 2020
Journal: Nat Commun
Title: ATR is essential for preservation of cell mechanics and nuclear integrity during interstitial migration.
Volume: 11
Issue: 1
Pages: 4828
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Publication
18245444 | J:131573
First Author: Toledo LI
Year: 2008
Journal: Genes Dev
Title: ATR signaling can drive cells into senescence in the absence of DNA breaks.
Volume: 22
Issue: 3
Pages: 297-302
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Publication
20818375 | J:164430
First Author: Liu H
Year: 2010
Journal: Nature
Title: Phosphorylation of MLL by ATR is required for execution of mammalian S-phase checkpoint.
Volume: 467
Issue: 7313
Pages: 343-6
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Publication
20212315 | J:157978
First Author: McNees CJ
Year: 2010
Journal: J Cell Biol
Title: ATR suppresses telomere fragility and recombination but is dispensable for elongation of short telomeres by telomerase.
Volume: 188
Issue: 5
Pages: 639-52
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Publication
28273450 | J:251063
First Author: Chen CF
Year: 2017
Journal: Cell Rep
Title: ATR Mutations Promote the Growth of Melanoma Tumors by Modulating the Immune Microenvironment.
Volume: 18
Issue: 10
Pages: 2331-2342
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Publication
14718568 | J:90049
First Author: Perera D
Year: 2004
Journal: Mol Biol Cell
Title: TopBP1 and ATR colocalization at meiotic chromosomes: role of TopBP1/Cut5 in the meiotic recombination checkpoint.
Volume: 15
Issue: 4
Pages: 1568-79
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Publication
23297361 | J:280203
First Author: Valdés-Sánchez L
Year: 2013
Journal: Hum Mol Genet
Title: ATR localizes to the photoreceptor connecting cilium and deficiency leads to severe photoreceptor degeneration in mice.
Volume: 22
Issue: 8
Pages: 1507-15
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Publication
27067599 | J:249000
First Author: Ruiz S
Year: 2016
Journal: Mol Cell
Title: A Genome-wide CRISPR Screen Identifies CDC25A as a Determinant of Sensitivity to ATR Inhibitors.
Volume: 62
Issue: 2
Pages: 307-13
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Publication
16213462 | J:102731
First Author: Ouyang Y
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Inhibition of Atm and/or Atr disrupts gene silencing on the inactive X chromosome.
Volume: 337
Issue: 3
Pages: 875-80
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Publication
19718024 | J:155013
First Author: Ruzankina Y
Year: 2009
Journal: Nat Genet
Title: Tissue regenerative delays and synthetic lethality in adult mice after combined deletion of Atr and Trp53.
Volume: 41
Issue: 10
Pages: 1144-9
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Publication
15282542 | J:92291
First Author: Fang Y
Year: 2004
Journal: EMBO J
Title: ATR functions as a gene dosage-dependent tumor suppressor on a mismatch repair-deficient background.
Volume: 23
Issue: 15
Pages: 3164-74
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Publication
29279380 | J:258375
First Author: Cheng A
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: ATM and ATR play complementary roles in the behavior of excitatory and inhibitory vesicle populations.
Volume: 115
Issue: 2
Pages: E292-E301
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Publication
31589169 | J:280953
First Author: Kishi S
Year: 2019
Journal: J Clin Invest
Title: Proximal tubule ATR regulates DNA repair to prevent maladaptive renal injury responses.
Volume: 129
Issue: 11
Pages: 4797-4816
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Publication
18691676 | J:142971
First Author: Kedar PS
Year: 2008
Journal: DNA Repair (Amst)
Title: Interaction between PARP-1 and ATR in mouse fibroblasts is blocked by PARP inhibition.
Volume: 7
Issue: 11
Pages: 1787-98
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Publication
18160412 | J:172160
First Author: Entezam A
Year: 2008
Journal: Nucleic Acids Res
Title: ATR protects the genome against CGG.CCG-repeat expansion in Fragile X premutation mice.
Volume: 36
Issue: 3
Pages: 1050-6
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Publication
18371340 | J:123200
First Author: Ruzankina Y
Year: 2007
Journal: Cell Stem Cell
Title: Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss.
Volume: 1
Issue: 1
Pages: 113-26
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Publication
17687332 | J:125120
First Author: Denchi EL
Year: 2007
Journal: Nature
Title: Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1.
Volume: 448
Issue: 7157
Pages: 1068-71
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Publication
27803059 | J:237522
First Author: Lang PY
Year: 2016
Journal: Development
Title: ATR maintains chromosomal integrity during postnatal cerebellar neurogenesis and is required for medulloblastoma formation.
Volume: 143
Issue: 21
Pages: 4038-4052
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Publication
18606783 | J:139870
First Author: Hitomi M
Year: 2008
Journal: Mol Cell Biol
Title: Phosphorylation of cyclin D1 regulated by ATM or ATR controls cell cycle progression.
Volume: 28
Issue: 17
Pages: 5478-93
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Publication
21098704 | J:166996
First Author: Gilad O
Year: 2010
Journal: Cancer Res
Title: Combining ATR suppression with oncogenic Ras synergistically increases genomic instability, causing synthetic lethality or tumorigenesis in a dosage-dependent manner.
Volume: 70
Issue: 23
Pages: 9693-702
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Publication
18344416 | J:136629
First Author: Kulkarni A
Year: 2008
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Differential roles of ATR and ATM in p53, Chk1, and histone H2AX phosphorylation in response to hyperoxia: ATR-dependent ATM activation.
Volume: 294
Issue: 5
Pages: L998-L1006
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Publication
19710035 | J:173019
First Author: Entezam A
Year: 2009
Journal: Nucleic Acids Res
Title: ATM and ATR protect the genome against two different types of tandem repeat instability in Fragile X premutation mice.
Volume: 37
Issue: 19
Pages: 6371-7
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Publication
33110058 | J:299031
First Author: Matos-Rodrigues GE
Year: 2020
Journal: Cell Death Dis
Title: ATRIP protects progenitor cells against DNA damage in vivo.
Volume: 11
Issue: 10
Pages: 923
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Publication
32994318 | J:297493
 
First Author: Matos-Rodrigues GE
Year: 2020
Journal: Dis Model Mech
Title: Progenitor death drives retinal dysplasia and neuronal degeneration in a mouse model of ATRIP-Seckel syndrome.
Volume: 13
Issue: 10
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Publication
28036033 | J:320282
 
First Author: Feng W
Year: 2016
Journal: Genes (Basel)
Title: Mec1/ATR, the Program Manager of Nucleic Acids Inc.
Volume: 8
Issue: 1
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Publication
29125140 | J:296112
First Author: Zhao B
Year: 2018
Journal: Cell Res
Title: Mouse embryonic stem cells have increased capacity for replication fork restart driven by the specific Filia-Floped protein complex.
Volume: 28
Issue: 1
Pages: 69-89
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Protein Coding Gene
MGI:1925349 | Atrip
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
22549958 | J:183982
First Author: Wojtasz L
Year: 2012
Journal: Genes Dev
Title: Meiotic DNA double-strand breaks and chromosome asynapsis in mice are monitored by distinct HORMAD2-independent and -dependent mechanisms.
Volume: 26
Issue: 9
Pages: 958-73
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Publication
21693576 | J:183045
First Author: Refolio E
Year: 2011
Journal: J Cell Sci
Title: The Ddc2/ATRIP checkpoint protein monitors meiotic recombination intermediates.
Volume: 124
Issue: Pt 14
Pages: 2488-500
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Publication
23950734 | J:200981
First Author: Zhou ZW
Year: 2013
Journal: PLoS Genet
Title: An essential function for the ATR-activation-domain (AAD) of TopBP1 in mouse development and cellular senescence.
Volume: 9
Issue: 8
Pages: e1003702
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Author
Noll ATR
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Publication
22471438 | J:198034
First Author: Onksen JL
Year: 2012
Journal: Genes Brain Behav
Title: Running-induced anxiety is dependent on increases in hippocampal neurogenesis.
Volume: 11
Issue: 5
Pages: 529-38
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Publication
19805627 | J:153811
First Author: Smith KD
Year: 2009
Journal: J Cell Biol
Title: Tim-Tipin dysfunction creates an indispensible reliance on the ATR-Chk1 pathway for continued DNA synthesis.
Volume: 187
Issue: 1
Pages: 15-23
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Publication
26778124 | J:233038
First Author: Kibe T
Year: 2016
Journal: Mol Cell
Title: TPP1 Blocks an ATR-Mediated Resection Mechanism at Telomeres.
Volume: 61
Issue: 2
Pages: 236-46
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Publication
34158506 | J:343910
First Author: Li F
Year: 2021
Journal: Nat Commun
Title: The Atr-Chek1 pathway inhibits axon regeneration in response to Piezo-dependent mechanosensation.
Volume: 12
Issue: 1
Pages: 3845
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Publication
22370720 | J:182697
First Author: López-Contreras AJ
Year: 2012
Journal: J Exp Med
Title: An extra allele of Chk1 limits oncogene-induced replicative stress and promotes transformation.
Volume: 209
Issue: 3
Pages: 455-61
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Publication
19596237 | J:157331
First Author: Sfeir A
Year: 2009
Journal: Cell
Title: Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication.
Volume: 138
Issue: 1
Pages: 90-103
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Publication
22099311 | J:178606
First Author: Takai KK
Year: 2011
Journal: Mol Cell
Title: Telomere protection by TPP1/POT1 requires tethering to TIN2.
Volume: 44
Issue: 4
Pages: 647-59
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Publication
24142876 | J:202921
First Author: Ragland RL
Year: 2013
Journal: Genes Dev
Title: RNF4 and PLK1 are required for replication fork collapse in ATR-deficient cells.
Volume: 27
Issue: 20
Pages: 2259-73
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Publication
15589157 | J:95016
First Author: Turner JM
Year: 2004
Journal: Curr Biol
Title: BRCA1, histone H2AX phosphorylation, and male meiotic sex chromosome inactivation.
Volume: 14
Issue: 23
Pages: 2135-42
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Publication
21593482 | J:176702
First Author: Mu XF
Year: 2011
Journal: Biol Reprod
Title: DNA damage-sensing kinases mediate the mouse 2-cell embryo's response to genotoxic stress.
Volume: 85
Issue: 3
Pages: 524-35
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Publication
15983387 | J:99862
First Author: Ishii H
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Frag1, a homolog of alternative replication factor C subunits, links replication stress surveillance with apoptosis.
Volume: 102
Issue: 27
Pages: 9655-60
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Publication
19620979 | J:151542
First Author: Murga M
Year: 2009
Journal: Nat Genet
Title: A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging.
Volume: 41
Issue: 8
Pages: 891-8
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Publication
15998665 | J:100203
First Author: Bellani MA
Year: 2005
Journal: J Cell Sci
Title: SPO11 is required for sex-body formation, and Spo11 heterozygosity rescues the prophase arrest of Atm-/- spermatocytes.
Volume: 118
Issue: Pt 15
Pages: 3233-45
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Publication
22133876 | J:184414
First Author: Schoppy DW
Year: 2012
Journal: J Clin Invest
Title: Oncogenic stress sensitizes murine cancers to hypomorphic suppression of ATR.
Volume: 122
Issue: 1
Pages: 241-52
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Publication
21844338 | J:175235
First Author: Kawasumi M
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Protection from UV-induced skin carcinogenesis by genetic inhibition of the ataxia telangiectasia and Rad3-related (ATR) kinase.
Volume: 108
Issue: 33
Pages: 13716-21
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Publication
24899707 | J:211631
First Author: Lee Y
Year: 2014
Journal: J Neurosci
Title: Pot1a prevents telomere dysfunction and ATM-dependent neuronal loss.
Volume: 34
Issue: 23
Pages: 7836-44
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Publication
28620865 | J:309383
First Author: Kim J
Year: 2017
Journal: Histochem Cell Biol
Title: Involvement of Atm and Trp53 in neural cell loss due to Terf2 inactivation during mouse brain development.
Volume: 148
Issue: 5
Pages: 489-501
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Publication
21478856 | J:173089
First Author: Daniel K
Year: 2011
Journal: Nat Cell Biol
Title: Meiotic homologue alignment and its quality surveillance are controlled by mouse HORMAD1.
Volume: 13
Issue: 5
Pages: 599-610
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Protein Coding Gene
MGP_CAROLIEiJ_G0032534 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0035139 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0035120 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0035052 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0035113 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0034823 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_108028 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0035633 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0034135 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0034791 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0034953 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0034901 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0035032 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0034940 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0035655 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0033842 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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