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Search results 1401 to 1500 out of 1504 for Map2

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Type Details Score
GXD Expression
GXD Expression
Probe: MGI:5448449
Assay Type: Immunohistochemistry
Annotation Date: 2013-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283722
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:5448638
Age: embryonic day 14.5
Image: 5B
Note: Expression was detected in differentiating neurons. Co-expression with Mdm20 (Naa25) and Map2 was noted.
Specimen Label: 5B
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
Probe: MGI:5448449
Assay Type: Immunohistochemistry
Annotation Date: 2013-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283726
Pattern: Non-Uniform
Stage: TS26
Assay Id: MGI:5448638
Age: embryonic day 18.5
Image: 7S
Note: Expression was detected in differentiated neurons. Co-expression with Mdm20 (Naa25) and Map2 was noted.
Specimen Label: 7S
Detected: true
Specimen Num: 36
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GXD Expression
GXD Expression
Probe: MGI:5448447
Assay Type: Immunohistochemistry
Annotation Date: 2013-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3524826
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:5448461
Age: embryonic day 18.5
Image: 7V
Note: Expression was detected in differentiated neurons. Co-expression with Nat5 (Naa20) and Map2 was noted.
Specimen Label: 7V
Detected: true
Specimen Num: 41
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GXD Expression
GXD Expression
 
Probe: MGI:6504887
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-04
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3525628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6504894
Age: postnatal adult
Note: Expression particularly high in layers II/III and V/VI. Expression colocalized with Map2 indicating expression in neurons,.
Specimen Label: 3a
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:3056767
Assay Type: Immunohistochemistry
Annotation Date: 2023-08-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3686928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7520303
Age: postnatal adult
Image: S2E
Note: Coexpressed with Map2 and Gad1 in small GABAergic neurons in lateral deep cerebellar nucleus.
Specimen Label: S2E
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
 
Probe: MGI:7520302
Assay Type: Immunohistochemistry
Annotation Date: 2023-08-23
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3686928
Stage: TS28
Assay Id: MGI:7520306
Age: postnatal adult
Image: S2F
Note: Not coexpressed with Map2 and Gad1 in lateral deep cerebellar nucleus.
Specimen Label: S2F
Detected: false
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:3056767
Assay Type: Immunohistochemistry
Annotation Date: 2023-08-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3687028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7520303
Age: postnatal adult
Image: S2A
Note: Coexpressed with Map2 and Gad1 in small GABAergic neurons in medial cerebellar nucleus.
Specimen Label: S2A
Detected: true
Specimen Num: 10
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Protein
Q63844
Organism: Mus musculus/domesticus
Length: 380  
Fragment?: false
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GXD Expression
GXD Expression
Probe: MGI:5448447
Assay Type: Immunohistochemistry
Annotation Date: 2013-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1755022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5448461
Age: embryonic day 14.5
Image: 6H
Note: Expression was detected in differentiating neurons of the external cuneate nucleus. Co-expression with Nat5 (Naa20) and Map2 was noted.
Specimen Label: 6H
Detected: true
Specimen Num: 28
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GXD Expression
GXD Expression
Probe: MGI:5448447
Assay Type: Immunohistochemistry
Annotation Date: 2013-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1755026
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:5448461
Age: embryonic day 18.5
Image: 7X
Note: Expression was detected in differentiated neurons of the external cuneate nucleus. Co-expression with Nat5 (Naa20) and Map2 was noted.
Specimen Label: 7X
Detected: true
Specimen Num: 43
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GXD Expression
GXD Expression
Probe: MGI:5448449
Assay Type: Immunohistochemistry
Annotation Date: 2013-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1755022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5448638
Age: embryonic day 14.5
Image: 6H
Note: Expression was detected in differentiating neurons of the external cuneate nucleus. Co-expression with Mdm20 (Naa25) and Map2 was noted.
Specimen Label: 6H
Detected: true
Specimen Num: 26
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GXD Expression
GXD Expression
Probe: MGI:5448449
Assay Type: Immunohistochemistry
Annotation Date: 2013-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1755026
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:5448638
Age: embryonic day 18.5
Image: 7X
Note: Expression was detected in differentiated neurons of the external cuneate nucleus. Co-expression with Mdm20 (Naa25) and Map2 was noted.
Specimen Label: 7X
Detected: true
Specimen Num: 41
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GXD Expression
GXD Expression
Probe: MGI:5448447
Assay Type: Immunohistochemistry
Annotation Date: 2013-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1755722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5448461
Age: embryonic day 14.5
Image: 6F
Note: Expression was detected in differentiating neurons of the medullary raphe. Co-expression with Nat5 (Naa20) and Map2 was noted.
Specimen Label: 6F
Detected: true
Specimen Num: 26
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GXD Expression
GXD Expression
Probe: MGI:5448449
Assay Type: Immunohistochemistry
Annotation Date: 2013-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1755722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5448638
Age: embryonic day 14.5
Image: 6F
Note: Expression was detected in differentiating neurons of the medullary raphe. Co-expression with Mdm20 (Naa25) and Map2 was noted.
Specimen Label: 6F
Detected: true
Specimen Num: 24
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GXD Expression
GXD Expression
 
Probe: MGI:6504887
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-04
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6504894
Age: postnatal adult
Note: Highest density of expression in pyramidal cells of CA3 region. Expression colocalized with Map2 indicating expression in neurons,.
Specimen Label: 3b
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:5448447
Assay Type: Immunohistochemistry
Annotation Date: 2013-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1756322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5448461
Age: embryonic day 14.5
Image: 6D
Note: Expression was detected in differentiating neurons of the cochlear nucleus. Co-expression with Nat5 (Naa20) and Map2 was noted.
Specimen Label: 6D
Detected: true
Specimen Num: 24
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GXD Expression
GXD Expression
Probe: MGI:5448447
Assay Type: Immunohistochemistry
Annotation Date: 2013-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1756326
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:5448461
Age: embryonic day 18.5
Image: 7W
Note: Expression was detected in differentiated neurons of the pontine reticular formation. Co-expression with Nat5 (Naa20) and Map2 was noted.
Specimen Label: 7W
Detected: true
Specimen Num: 42
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GXD Expression
GXD Expression
Probe: MGI:5448449
Assay Type: Immunohistochemistry
Annotation Date: 2013-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1756322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5448638
Age: embryonic day 14.5
Image: 6D
Note: Expression was detected in differentiating neurons of the cochlear nucleus. Co-expression with Mdm20 (Naa25) and Map2 was noted.
Specimen Label: 6D
Detected: true
Specimen Num: 22
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GXD Expression
GXD Expression
Probe: MGI:5448449
Assay Type: Immunohistochemistry
Annotation Date: 2013-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1756326
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:5448638
Age: embryonic day 18.5
Image: 7V
Note: Expression was detected in differentiated neurons in the cochlear nucleus. Co-expression with Mdm20 (Naa25) and Map2 was noted.
Specimen Label: 7V
Detected: true
Specimen Num: 39
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GXD Expression
GXD Expression
Probe: MGI:5448449
Assay Type: Immunohistochemistry
Annotation Date: 2013-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1756326
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:5448638
Age: embryonic day 18.5
Image: 7W
Note: Expression was detected in differentiated neurons of the pontine reticular formation. Co-expression with Mdm20 (Naa25) and Map2 was noted.
Specimen Label: 7W
Detected: true
Specimen Num: 40
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Allele
Map2<tm1Noh> | MGI:2152587
Name: microtubule-associated protein 2; targeted mutation 1, Nobutaka Hirokawa
Allele Type: Targeted
Attribute String: Null/knockout
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GXD Expression
GXD Expression
Probe: MGI:5448447
Assay Type: Immunohistochemistry
Annotation Date: 2013-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3593022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5448461
Age: embryonic day 14.5
Image: 5H
Note: Expression was detected in differentiating neurons of the bed nucleus stria terminalis and zona incerta. Co-expression with Nat5 (Naa20) and Map2 was noted.
Specimen Label: 5H
Detected: true
Specimen Num: 19
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GXD Expression
GXD Expression
Probe: MGI:5448449
Assay Type: Immunohistochemistry
Annotation Date: 2013-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3593022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5448638
Age: embryonic day 14.5
Image: 5H
Note: Expression was detected in differentiating neurons of the bed nucleus stria terminalis and zona incerta. Co-expression with Mdm20 (Naa25) and Map2 was noted.
Specimen Label: 5H
Detected: true
Specimen Num: 17
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GXD Expression
GXD Expression
Probe: MGI:5448447
Assay Type: Immunohistochemistry
Annotation Date: 2013-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5448461
Age: embryonic day 14.5
Image: 5H
Note: Expression was detected in differentiating neurons of the bed nucleus stria terminalis and zona incerta. Co-expression with Nat5 (Naa20) and Map2 was noted.
Specimen Label: 5H
Detected: true
Specimen Num: 19
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GXD Expression
GXD Expression
Probe: MGI:5448449
Assay Type: Immunohistochemistry
Annotation Date: 2013-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5448638
Age: embryonic day 14.5
Image: 5H
Note: Expression was detected in differentiating neurons of the bed nucleus stria terminalis and zona incerta. Co-expression with Mdm20 (Naa25) and Map2 was noted.
Specimen Label: 5H
Detected: true
Specimen Num: 17
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GXD Expression
GXD Expression
 
Probe: MGI:6798117
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1715720
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7461127
Age: embryonic day 12.5
Note: Expression within the sympathetic chain was restricted to the three to four anterior-most, upper thoracic ganglia. Co-labeling with Map2 indicated the staining was associated with differentiating neurons.
Specimen Label: 7A
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
 
Probe: MGI:6798117
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1757720
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7461127
Age: embryonic day 12.5
Note: Expression was strong in the ventral horn of the spinal cord. Co-labeling with Map2 indicated the staining was associated with differentiating neurons.
Specimen Label: 7A
Detected: true
Specimen Num: 11
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Genotype
Genotype
Symbol: Map2/Map2
Background: involves: C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Map1b/Map1b Map2/Map2
Background: involves: C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Protein Domain
IPR029899 | KNDC1
Type: Family
Description: Kinase noncatalytic C-lobe domain containing 1 (KNDC1), also known as very-KIND, is a brain-specific Ras guanine nucleotide exchange factor (RasGEF) that regulates microtubule-associated protein 2 (MAP2) during dendrite morphogenesis [, ]. It contains two kinase noncatalytic C-lobe domains (KIND1 and KIND2), a RasGEF N-terminal domain (RasN) and a putative RasGEF domain []. The KIND2 domain regulates dendrite complexity via targeting of v-KIND to MAP2 associated with the dendritic microtubule cytoskeleton [].
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Protein
Q78TF3
Organism: Mus musculus/domesticus
Length: 99  
Fragment?: false
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Publication
12773533 | -
First Author: Tokuraku K
Year: 2003
Journal: J Biol Chem
Title: The number of repeat sequences in microtubule-associated protein 4 affects the microtubule surface properties.
Volume: 278
Issue: 32
Pages: 29609-18
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Publication
10791892 | -
First Author: Kitazawa H
Year: 2000
Journal: Cell Struct Funct
Title: Ser787 in the proline-rich region of human MAP4 is a critical phosphorylation site that reduces its activity to promote tubulin polymerization.
Volume: 25
Issue: 1
Pages: 33-9
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Publication
12855424 | J:133365
First Author: Takahashi M
Year: 2003
Journal: Am J Physiol Heart Circ Physiol
Title: Phenotypic consequences of beta1-tubulin expression and MAP4 decoration of microtubules in adult cardiocytes.
Volume: 285
Issue: 5
Pages: H2072-83
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Publication
20436166 | -
First Author: Chinnakkannu P
Year: 2010
Journal: J Biol Chem
Title: Site-specific microtubule-associated protein 4 dephosphorylation causes microtubule network densification in pressure overload cardiac hypertrophy.
Volume: 285
Issue: 28
Pages: 21837-48
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Publication
15840946 | -
First Author: Permana S
Year: 2005
Journal: Cell Struct Funct
Title: Truncation of the projection domain of MAP4 (microtubule-associated protein 4) leads to attenuation of microtubule dynamic instability.
Volume: 29
Issue: 5-6
Pages: 147-57
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Protein Domain
IPR027323 | MAP4
Type: Family
Description: Microtubule-associated protein 4 (MAP4) is a non-neuronal microtubule-associated protein that promotes microtubule assembly [, ]. It contains a microtubule binding domain (Tau/MAP repeats) that shares homology with neuronal microtubule-associated protein MAP2 and Tau []. It is a ubiquitous heat-stable MAP responsible for stabilisation of microtubules []. Overexpression of MAP4 causes a shift of tubulin dimers to a polymerised fraction and formed dense, stable microtubule networks []. The persistent transcriptional up-regulation of MAP4, cardiac alpha- and beta-tubulinis is linked to the cytoskeletal abnormality during severe pressure overload-induced cardiac hypertrophy [].
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Protein
P27546
Organism: Mus musculus/domesticus
Length: 1125  
Fragment?: false
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Protein
A0A0G2JFK3
Organism: Mus musculus/domesticus
Length: 207  
Fragment?: true
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Protein
E9PZ43
Organism: Mus musculus/domesticus
Length: 933  
Fragment?: false
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Protein
A0A0G2JFT4
Organism: Mus musculus/domesticus
Length: 276  
Fragment?: true
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Protein
A0A0G2JFH2
Organism: Mus musculus/domesticus
Length: 1441  
Fragment?: true
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Protein
A0A0G2JDU1
Organism: Mus musculus/domesticus
Length: 116  
Fragment?: true
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Protein
A0A140T8T5
Organism: Mus musculus/domesticus
Length: 414  
Fragment?: false
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Protein
A0A0G2JDY5
Organism: Mus musculus/domesticus
Length: 220  
Fragment?: true
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Protein
A0A0G2JG35
Organism: Mus musculus/domesticus
Length: 290  
Fragment?: true
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Protein
A0A0G2JDN7
Organism: Mus musculus/domesticus
Length: 902  
Fragment?: false
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Publication
16310870 | J:105032
First Author: Acevedo SF
Year: 2006
Journal: Behav Brain Res
Title: Anxiety and cognition in female histidine decarboxylase knockout (Hdc(-/-)) mice.
Volume: 168
Issue: 1
Pages: 92-9
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Publication
16790550 | J:111701
First Author: Yeh JR
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Targeted gene disruption of methionine aminopeptidase 2 results in an embryonic gastrulation defect and endothelial cell growth arrest.
Volume: 103
Issue: 27
Pages: 10379-84
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Publication
17640754 | J:124670
First Author: Ohkawa N
Year: 2007
Journal: Neurosci Res
Title: Motor discoordination of transgenic mice overexpressing a microtubule destabilizer, stathmin, specifically in Purkinje cells.
Volume: 59
Issue: 1
Pages: 93-100
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Publication
12689591 | J:109559
First Author: Chang L
Year: 2003
Journal: Dev Cell
Title: JNK1 is required for maintenance of neuronal microtubules and controls phosphorylation of microtubule-associated proteins.
Volume: 4
Issue: 4
Pages: 521-33
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Publication
12944471 | J:85467
First Author: Skryabin BV
Year: 2003
Journal: Mol Cell Biol
Title: Neuronal untranslated BC1 RNA: targeted gene elimination in mice.
Volume: 23
Issue: 18
Pages: 6435-41
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Publication
16099729 | J:103133
First Author: Mees A
Year: 2005
Journal: Gene Expr Patterns
Title: Very-KIND is a novel nervous system specific guanine nucleotide exchange factor for Ras GTPases.
Volume: 6
Issue: 1
Pages: 79-85
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Publication
25558816 | J:234457
First Author: Xia D
Year: 2015
Journal: Biochim Biophys Acta
Title: Pseudophosphorylation of Tau at distinct epitopes or the presence of the P301L mutation targets the microtubule-associated protein Tau to dendritic spines.
Volume: 1852
Issue: 5
Pages: 913-24
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Publication
30425286 | J:268145
First Author: Saddala MS
Year: 2018
Journal: Sci Rep
Title: Proteomics reveals ablation of PlGF increases antioxidant and neuroprotective proteins in the diabetic mouse retina.
Volume: 8
Issue: 1
Pages: 16728
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Publication
9618216 | J:91495
First Author: Dalpé G
Year: 1998
Journal: Mol Cell Neurosci
Title: Dystonin Is Essential for Maintaining Neuronal Cytoskeleton Organization.
Volume: 10
Issue: 5/6
Pages: 243-57
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Publication
19101630 | J:146301
First Author: Simón AM
Year: 2009
Journal: Neurobiol Dis
Title: Overexpression of wild-type human APP in mice causes cognitive deficits and pathological features unrelated to Abeta levels.
Volume: 33
Issue: 3
Pages: 369-78
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Publication
24849348 | J:211349
First Author: Ma QL
Year: 2014
Journal: J Neurosci
Title: Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.
Volume: 34
Issue: 21
Pages: 7124-36
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Publication
31922229 | J:296741
First Author: Zhu Q
Year: 2020
Journal: Mol Med Rep
Title: Neural stem cell transplantation improves learning and memory by protecting cholinergic neurons and restoring synaptic impairment in an amyloid precursor protein/presenilin 1 transgenic mouse model of Alzheimer's disease.
Volume: 21
Issue: 3
Pages: 1172-1180
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Publication
10219973 | J:54292
First Author: Seabrook GR
Year: 1999
Journal: Neuropharmacology
Title: Mechanisms contributing to the deficits in hippocampal synaptic plasticity in mice lacking amyloid precursor protein.
Volume: 38
Issue: 3
Pages: 349-59
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Publication
17344389 | J:120105
First Author: Su KY
Year: 2007
Journal: J Neurosci
Title: Mice deficient in collapsin response mediator protein-1 exhibit impaired long-term potentiation and impaired spatial learning and memory.
Volume: 27
Issue: 10
Pages: 2513-24
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Publication
8287193 | J:16255
First Author: Solà C
Year: 1993
Journal: Eur J Neurosci
Title: Regional distribution of amyloid beta-protein precursor, growth-associated phosphoprotein-43 and microtubule-associated protein 2 messenger RNAs in the nigrostriatal system of normal and Weaver mutant mice and effects of ventral mesencephalic grafts.
Volume: 5
Issue: 11
Pages: 1442-54
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Publication
11754076 | J:288770
First Author: Tanaka H
Year: 2002
Journal: J Neurosci Res
Title: Disturbance of hippocampal long-term potentiation after transient ischemia in GFAP deficient mice.
Volume: 67
Issue: 1
Pages: 11-20
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Publication
12151531 | J:78091
First Author: Bu B
Year: 2002
Journal: J Neurosci
Title: Deregulation of cdk5, hyperphosphorylation, and cytoskeletal pathology in the Niemann-Pick type C murine model.
Volume: 22
Issue: 15
Pages: 6515-25
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Publication
25133820 | J:223142
First Author: Purohit P
Year: 2014
Journal: PLoS One
Title: The Ca2+ sensor protein swiprosin-1/EFhd2 is present in neurites and involved in kinesin-mediated transport in neurons.
Volume: 9
Issue: 8
Pages: e103976
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Publication
15223375 | J:91007
First Author: Kitano H
Year: 2004
Journal: Brain Res
Title: ORP150 ameliorates ischemia/reperfusion injury from middle cerebral artery occlusion in mouse brain.
Volume: 1015
Issue: 1-2
Pages: 122-8
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Publication
15269255 | J:102186
First Author: Fonseca MI
Year: 2004
Journal: J Neurosci
Title: Absence of C1q leads to less neuropathology in transgenic mouse models of Alzheimer's disease.
Volume: 24
Issue: 29
Pages: 6457-65
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Publication
28939435 | J:256872
First Author: Silva AC
Year: 2018
Journal: Biochim Biophys Acta
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Protein
D3Z3X0
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Fragment?: false
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