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Search results 501 to 549 out of 549 for Hdgf

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0.025s
Type Details Score
Strain
Attribute String: coisogenic, targeted mutation
Genotype
Symbol: Hdgfl2/Hdgfl2
Background: involves: 129S5/SvEvBrd * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Hdgfl3/Hdgfl3
Background: C57BL/6NCrl-Hdgfl3/Tcp
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Hdgfl1/Hdgfl1
Background: C57BL/6NCrl-Hdgfl1/Tcp
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Hdgfl2/Hdgfl2
Background: C57BL/6N-Hdgfl2/Tcp
Zygosity: hm
Has Mutant Allele: true
Strain
Attribute String: endonuclease-mediated mutation, mutant stock
Genotype
Symbol: Hdgfl1/Hdgfl1
Background: involves: C57BL/6NJcl * DBA/2NJcl
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Hdgfl1/Hdgfl1<+>
Background: C57BL/6NCrl-Hdgfl1/Tcp
Zygosity: ht
Has Mutant Allele: true
Publication
First Author: Zhu X
Year: 2020
Journal: Nucleic Acids Res
Title: HRP2-DPF3a-BAF complex coordinates histone modification and chromatin remodeling to regulate myogenic gene transcription.
Volume: 48
Issue: 12
Pages: 6563-6582
Publication
First Author: Sun J
Year: 2020
Journal: Biol Reprod
Title: CRISPR/Cas9-based genome editing in mice uncovers 13 testis- or epididymis-enriched genes individually dispensable for male reproduction†.
Volume: 103
Issue: 2
Pages: 183-194
Publication  
First Author: Yang J
Year: 2007
Journal: BMC Mol Biol
Title: Hepatoma-derived growth factor binds DNA through the N-terminal PWWP domain.
Volume: 8
Pages: 101
Publication
First Author: Dietz F
Year: 2002
Journal: Biochem J
Title: The family of hepatoma-derived growth factor proteins: characterization of a new member HRP-4 and classification of its subfamilies.
Volume: 366
Issue: Pt 2
Pages: 491-500
Publication
First Author: Bao C
Year: 2014
Journal: Future Oncol
Title: HDGF: a novel jack-of-all-trades in cancer.
Volume: 10
Issue: 16
Pages: 2675-85
Protein Domain
Type: Domain
Description: The PWWP domain is an essential part of the Hepatoma Derived Growth Factor (HDGF) family of proteins, and is necessary for DNA binding by HDGF [, , ]. This family of endogenous nuclear-targeted mitogens includes HRP (HDGF-related proteins 1, 2, 3, 4, or HRP1, HRP2, HRP3, HRP4, respectively) and lens epithelium-derived growth factor, LEDGF []. Members of the HDGF family have been linked to human diseases, and HDGF is a prognostic factor in several types of cancer [].The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins seem to be nuclear, often DNA-binding, proteins that function as transcription factors regulating a variety of developmental processes [].
Protein
Organism: Mus musculus/domesticus
Length: 202  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 283  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 327  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 260  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 178  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 90  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 283  
Fragment?: false
Publication      
First Author: The Centre for Phenogenomics
Year: 2022
Journal: MGI Direct Data Submission
Title: Direct Data Submission for The Centre for Phenogenomics Alleles.
Publication
First Author: Wang J
Year: 2017
Journal: Cell Death Dis
Title: MBD2 upregulates miR-301a-5p to induce kidney cell apoptosis during vancomycin-induced AKI.
Volume: 8
Issue: 10
Pages: e3120
Publication
First Author: Yoshida K
Year: 2003
Journal: J Gastroenterol Hepatol
Title: Expression of hepatoma-derived growth factor in hepatocarcinogenesis.
Volume: 18
Issue: 11
Pages: 1293-301
Protein
Organism: Mus musculus/domesticus
Length: 669  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 528  
Fragment?: false
Publication
First Author: Stec I
Year: 2000
Journal: FEBS Lett
Title: The PWWP domain: a potential protein-protein interaction domain in nuclear proteins influencing differentiation?
Volume: 473
Issue: 1
Pages: 1-5
HT Experiment
Series Id: GSE25965
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: ArrayExpress
Publication      
First Author: Toronto Centre for Phenogenomics
Year: 2013
Journal: MGI Direct Data Submission
Title: Strains and alleles submitted by Toronto Centre for Phenogenomics (NorCOMM2, funded by Genome Canada and Ontario Genomics Institute OGI-051).
Publication
First Author: Georgas K
Year: 2009
Journal: Dev Biol
Title: Analysis of early nephron patterning reveals a role for distal RV proliferation in fusion to the ureteric tip via a cap mesenchyme-derived connecting segment.
Volume: 332
Issue: 2
Pages: 273-86
Publication      
First Author: Mutant Mouse Regional Resource Centers
Year: 2004
Journal: Unpublished
Title: Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC)
Publication
First Author: Tang T
Year: 2010
Journal: Nat Biotechnol
Title: A mouse knockout library for secreted and transmembrane proteins.
Volume: 28
Issue: 7
Pages: 749-55
Publication      
First Author: Lexicon Genetics, Inc
Year: 2011
Journal: Database Download
Title: MGI download of Lexicon knockout data
Publication      
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use