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Search results 1 to 100 out of 228 for Hcn1

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Hits by Pathway

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Hits by Category

Type Details Score
Gene
348980 | HCN1
Type: gene
Organism: human
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Gene
471552 | HCN1
Type: gene
Organism: chimpanzee
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Gene
538255 | HCN1
Type: gene
Organism: cattle
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Gene
431590 | HCN1
Type: gene
Organism: chicken
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Gene
704286 | HCN1
Type: gene
Organism: macaque, rhesus
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Gene
100490760 | hcn1
Type: gene
Organism: frog, western clawed
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Gene
key_78558 | HCN1
Type: gene
Organism: rabbit, European
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Gene
84390 | Hcn1
Type: gene
Organism: rat
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Gene
612434 | HCN1
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:1096392 | Hcn1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
22100643 | J:178943
First Author: Giocomo LM
Year: 2011
Journal: Cell
Title: Grid cells use HCN1 channels for spatial scaling.
Volume: 147
Issue: 5
Pages: 1159-70
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Publication
15292205 | J:93990
First Author: Gravante B
Year: 2004
Journal: J Biol Chem
Title: Interaction of the pacemaker channel HCN1 with filamin A.
Volume: 279
Issue: 42
Pages: 43847-53
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Publication
19563776 | J:151647
First Author: Arimitsu T
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Activity-dependent regulation of HCN1 protein in cortical neurons.
Volume: 387
Issue: 1
Pages: 87-91
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Publication
19726656 | J:152452
First Author: Huang Z
Year: 2009
Journal: J Neurosci
Title: Loss of dendritic HCN1 subunits enhances cortical excitability and epileptogenesis.
Volume: 29
Issue: 35
Pages: 10979-88
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Publication
14651847 | J:86763
First Author: Nolan MF
Year: 2003
Journal: Cell
Title: The hyperpolarization-activated HCN1 channel is important for motor learning and neuronal integration by cerebellar Purkinje cells.
Volume: 115
Issue: 5
Pages: 551-64
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Publication
29444426 | J:271143
First Author: Garden DLF
Year: 2018
Journal: Cell Rep
Title: Inferior Olive HCN1 Channels Coordinate Synaptic Integration and Complex Spike Timing.
Volume: 22
Issue: 7
Pages: 1722-1733
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Publication
21358644 | J:172304
First Author: Huang Z
Year: 2011
Journal: Nat Neurosci
Title: Presynaptic HCN1 channels regulate Cav3.2 activity and neurotransmission at select cortical synapses.
Volume: 14
Issue: 4
Pages: 478-86
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Publication
19158287 | J:144849
First Author: Chen X
Year: 2009
Journal: J Neurosci
Title: HCN1 channel subunits are a molecular substrate for hypnotic actions of ketamine.
Volume: 29
Issue: 3
Pages: 600-9
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Publication
24125720 | J:211528
First Author: Akbor MM
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Possible involvement of Hcn1 ion channel in learning and memory dysfunction in SAMP8 mice.
Volume: 441
Issue: 1
Pages: 25-30
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Publication
24000178 | J:215847
First Author: Rinaldi A
Year: 2013
Journal: J Physiol
Title: HCN1 channels in cerebellar Purkinje cells promote late stages of learning and constrain synaptic inhibition.
Volume: 591
Issue: 22
Pages: 5691-709
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Publication
18093528 | J:136886
First Author: Tsay D
Year: 2007
Journal: Neuron
Title: HCN1 channels constrain synaptically evoked Ca2+ spikes in distal dendrites of CA1 pyramidal neurons.
Volume: 56
Issue: 6
Pages: 1076-89
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Publication
22099465 | J:178945
First Author: Hussaini SA
Year: 2011
Journal: Neuron
Title: Increased size and stability of CA1 and CA3 place fields in HCN1 knockout mice.
Volume: 72
Issue: 4
Pages: 643-53
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Publication
24409334 | J:229656
First Author: Pan Y
Year: 2014
Journal: PLoS One
Title: TRIP8b is required for maximal expression of HCN1 in the mouse retina.
Volume: 9
Issue: 1
Pages: e85850
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Publication
23821600 | J:241826
First Author: Stoenica L
Year: 2013
Journal: Dev Neurobiol
Title: HCN1 subunits contribute to the kinetics of I(h) in neonatal cortical plate neurons.
Volume: 73
Issue: 10
Pages: 785-97
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Publication
19515931 | J:150045
First Author: Giocomo LM
Year: 2009
Journal: J Neurosci
Title: Knock-out of HCN1 subunit flattens dorsal-ventral frequency gradient of medial entorhinal neurons in adult mice.
Volume: 29
Issue: 23
Pages: 7625-30
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Publication
23966682 | J:201062
First Author: Thuault SJ
Year: 2013
Journal: J Neurosci
Title: Prefrontal cortex HCN1 channels enable intrinsic persistent neural firing and executive memory function.
Volume: 33
Issue: 34
Pages: 13583-99
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Publication
28071723 | J:274461
 
First Author: Huang Z
Year: 2017
Journal: Sci Rep
Title: HCN1 channels reduce the rate of exocytosis from a subset of cortical synaptic terminals.
Volume: 7
Pages: 40257
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Publication
19019198 | J:143756
First Author: Knop GC
Year: 2008
Journal: Eur J Neurosci
Title: Light responses in the mouse retina are prolonged upon targeted deletion of the HCN1 channel gene.
Volume: 28
Issue: 11
Pages: 2221-30
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Publication
15550252 | J:94775
First Author: Nolan MF
Year: 2004
Journal: Cell
Title: A behavioral role for dendritic integration: HCN1 channels constrain spatial memory and plasticity at inputs to distal dendrites of CA1 pyramidal neurons.
Volume: 119
Issue: 5
Pages: 719-32
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Publication
22363812 | J:232018
First Author: Wilkars W
Year: 2012
Journal: PLoS One
Title: Regulation of axonal HCN1 trafficking in perforant path involves expression of specific TRIP8b isoforms.
Volume: 7
Issue: 2
Pages: e32181
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Publication
26807953 | J:248897
First Author: Sothilingam V
Year: 2016
Journal: PLoS One
Title: HCN1 Channels Enhance Rod System Responsivity in the Retina under Conditions of Light Exposure.
Volume: 11
Issue: 1
Pages: e0147728
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Publication
30886335 | J:302698
First Author: Shao LX
Year: 2019
Journal: Mol Psychiatry
Title: Functional coupling of Tmem74 and HCN1 channels regulates anxiety-like behavior in BLA neurons.
Volume: 24
Issue: 10
Pages: 1461-1477
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Publication
26740549 | J:229473
First Author: Schön C
Year: 2016
Journal: Hum Mol Genet
Title: Loss of HCN1 enhances disease progression in mouse models of CNG channel-linked retinitis pigmentosa and achromatopsia.
Volume: 25
Issue: 6
Pages: 1165-75
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GXD Expression
GXD Expression
   
Probe: MGI:6174718
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190484
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Hcn1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6174718
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190484
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Hcn1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6174718
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190484
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Hcn1
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6174718
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190484
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Hcn1
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6174718
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190484
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Hcn1
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6174718
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190484
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Hcn1
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6174718
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190484
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Hcn1
Detected: true
Specimen Num: 7
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Publication
20164346 | J:157832
First Author: Chen X
Year: 2010
Journal: J Neurosci
Title: Homeostatic regulation of synaptic excitability: tonic GABA(A) receptor currents replace I(h) in cortical pyramidal neurons of HCN1 knock-out mice.
Volume: 30
Issue: 7
Pages: 2611-22
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Publication
18003822 | J:127595
First Author: Nolan MF
Year: 2007
Journal: J Neurosci
Title: HCN1 channels control resting and active integrative properties of stellate cells from layer II of the entorhinal cortex.
Volume: 27
Issue: 46
Pages: 12440-51
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Publication
21555075 | J:174797
First Author: Piskorowski R
Year: 2011
Journal: Neuron
Title: TRIP8b splice forms act in concert to regulate the localization and expression of HCN1 channels in CA1 pyramidal neurons.
Volume: 70
Issue: 3
Pages: 495-509
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Publication
24368169 | J:259372
 
First Author: Phillips AM
Year: 2014
Journal: Neurobiol Dis
Title: Spike-and-wave discharge mediated reduction in hippocampal HCN1 channel function associates with learning deficits in a genetic mouse model of epilepsy.
Volume: 64
Pages: 30-5
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Publication
22948144 | J:192134
First Author: Ramakrishnan NA
Year: 2012
Journal: J Biol Chem
Title: HCN1 and HCN2 proteins are expressed in cochlear hair cells: HCN1 can form a ternary complex with protocadherin 15 CD3 and F-actin-binding filamin A or can interact with HCN2.
Volume: 287
Issue: 45
Pages: 37628-46
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Publication
22068599 | J:323160
 
First Author: Seeliger MW
Year: 2011
Journal: Nat Commun
Title: Modulation of rod photoreceptor output by HCN1 channels is essential for regular mesopic cone vision.
Volume: 2
Pages: 532
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Publication
18424000 | J:139374
First Author: Oertel D
Year: 2008
Journal: Neuroscience
Title: In the ventral cochlear nucleus Kv1.1 and subunits of HCN1 are colocalized at surfaces of neurons that have low-voltage-activated and hyperpolarization-activated conductances.
Volume: 154
Issue: 1
Pages: 77-86
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Publication
35972069 | J:330406
   
First Author: Merseburg A
Year: 2022
Journal: Elife
Title: Seizures, behavioral deficits, and adverse drug responses in two new genetic mouse models of HCN1 epileptic encephalopathy.
Volume: 11
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Publication
- | J:267552
     
First Author: Teixeira S
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Thump.
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Publication
22006928 | J:202583
First Author: Lolicato M
Year: 2011
Journal: J Biol Chem
Title: Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels.
Volume: 286
Issue: 52
Pages: 44811-20
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Publication
29335607 | J:257775
First Author: Mallory CS
Year: 2018
Journal: Nat Neurosci
Title: Grid scale drives the scale and long-term stability of place maps.
Volume: 21
Issue: 2
Pages: 270-282
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Publication
11328811 | J:70716
First Author: Moroni A
Year: 2001
Journal: J Biol Chem
Title: Hyperpolarization-activated cyclic nucleotide-gated channel 1 is a molecular determinant of the cardiac pacemaker current I(f).
Volume: 276
Issue: 31
Pages: 29233-41
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Publication
18936078 | J:176560
First Author: Momin A
Year: 2008
Journal: J Physiol
Title: Role of the hyperpolarization-activated current Ih in somatosensory neurons.
Volume: 586
Issue: 24
Pages: 5911-29
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Publication
19273581 | J:176542
First Author: Orio P
Year: 2009
Journal: J Physiol
Title: Characteristics and physiological role of hyperpolarization activated currents in mouse cold thermoreceptors.
Volume: 587
Issue: Pt 9
Pages: 1961-76
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Publication
24218458 | J:219164
First Author: Fenske S
Year: 2013
Journal: Circulation
Title: Sick sinus syndrome in HCN1-deficient mice.
Volume: 128
Issue: 24
Pages: 2585-94
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Publication
12668666 | J:84105
First Author: Lesso H
Year: 2003
Journal: J Biol Chem
Title: Helical secondary structure of the external S3-S4 linker of pacemaker (HCN) channels revealed by site-dependent perturbations of activation phenotype.
Volume: 278
Issue: 25
Pages: 22290-7
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Publication
27425615 | J:238663
First Author: Matsumoto-Makidono Y
Year: 2016
Journal: Cell Rep
Title: Ionic Basis for Membrane Potential Resonance in Neurons of the Inferior Olive.
Volume: 16
Issue: 4
Pages: 994-1004
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Publication
19555649 | J:154954
First Author: Santoro B
Year: 2009
Journal: Neuron
Title: TRIP8b splice variants form a family of auxiliary subunits that regulate gating and trafficking of HCN channels in the brain.
Volume: 62
Issue: 6
Pages: 802-13
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Publication
17548059 | J:122280
First Author: Ishii TM
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Peripheral N- and C-terminal domains determine deactivation kinetics of HCN channels.
Volume: 359
Issue: 3
Pages: 592-8
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Publication
14676285 | J:87482
First Author: Bell DC
Year: 2004
Journal: J Gen Physiol
Title: Changes in local S4 environment provide a voltage-sensing mechanism for mammalian hyperpolarization-activated HCN channels.
Volume: 123
Issue: 1
Pages: 5-19
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Publication
14676284 | J:87438
First Author: Vemana S
Year: 2004
Journal: J Gen Physiol
Title: S4 movement in a mammalian HCN channel.
Volume: 123
Issue: 1
Pages: 21-32
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Publication
26898775 | J:240160
First Author: Maroso M
Year: 2016
Journal: Neuron
Title: Cannabinoid Control of Learning and Memory through HCN Channels.
Volume: 89
Issue: 5
Pages: 1059-73
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Publication
9634236 | J:48083
First Author: Ludwig A
Year: 1998
Journal: Nature
Title: A family of hyperpolarization-activated mammalian cation channels.
Volume: 393
Issue: 6685
Pages: 587-91
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Publication
22279546 | J:184238
First Author: Della Santina L
Year: 2012
Journal: PLoS One
Title: Processing of retinal signals in normal and HCN deficient mice.
Volume: 7
Issue: 1
Pages: e29812
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Publication
19524546 | J:153459
First Author: Rozario AO
Year: 2009
Journal: Biochim Biophys Acta
Title: Voltage-dependent opening of HCN channels: Facilitation or inhibition by the phytoestrogen, genistein, is determined by the activation status of the cyclic nucleotide gating ring.
Volume: 1788
Issue: 9
Pages: 1939-49
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Publication
16043489 | J:320090
First Author: Stieber J
Year: 2005
Journal: J Biol Chem
Title: Functional expression of the human HCN3 channel.
Volume: 280
Issue: 41
Pages: 34635-43
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Publication
9630217 | J:47845
First Author: Santoro B
Year: 1998
Journal: Cell
Title: Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain.
Volume: 93
Issue: 5
Pages: 717-29
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Publication
24403084 | J:213019
First Author: Noam Y
Year: 2014
Journal: J Biol Chem
Title: Filamin A promotes dynamin-dependent internalization of hyperpolarization-activated cyclic nucleotide-gated type 1 (HCN1) channels and restricts Ih in hippocampal neurons.
Volume: 289
Issue: 9
Pages: 5889-903
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Publication
24638995 | J:303019
First Author: Horwitz GC
Year: 2014
Journal: J Gen Physiol
Title: Mechanotransduction and hyperpolarization-activated currents contribute to spontaneous activity in mouse vestibular ganglion neurons.
Volume: 143
Issue: 4
Pages: 481-97
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Publication
22090507 | J:177907
First Author: Horwitz GC
Year: 2011
Journal: J Neurosci
Title: HCN channels expressed in the inner ear are necessary for normal balance function.
Volume: 31
Issue: 46
Pages: 16814-25
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Publication
28131828 | J:251360
First Author: Wu C
Year: 2017
Journal: Biochem Biophys Res Commun
Title: EP3 activation facilitates bladder excitability via HCN channels on ICCs.
Volume: 485
Issue: 2
Pages: 535-541
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Publication
22652004 | J:330478
First Author: Hofmann F
Year: 2012
Journal: Cardiovasc Res
Title: Ventricular HCN channels decrease the repolarization reserve in the hypertrophic heart.
Volume: 95
Issue: 3
Pages: 317-26
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Publication
21593326 | J:173355
First Author: Lewis AS
Year: 2011
Journal: J Neurosci
Title: Deletion of the hyperpolarization-activated cyclic nucleotide-gated channel auxiliary subunit TRIP8b impairs hippocampal Ih localization and function and promotes antidepressant behavior in mice.
Volume: 31
Issue: 20
Pages: 7424-40
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Publication
27965425 | J:259511
First Author: Zhang K
Year: 2016
Journal: Sci Signal
Title: Essential roles of AMPA receptor GluA1 phosphorylation and presynaptic HCN channels in fast-acting antidepressant responses of ketamine.
Volume: 9
Issue: 458
Pages: ra123
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Publication
22880098 | J:189820
First Author: Ying SW
Year: 2012
Journal: PLoS One
Title: Targeted deletion of Kcne2 impairs HCN channel function in mouse thalamocortical circuits.
Volume: 7
Issue: 8
Pages: e42756
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Publication
15564593 | J:96808
First Author: Santoro B
Year: 2004
Journal: J Neurosci
Title: Regulation of HCN channel surface expression by a novel C-terminal protein-protein interaction.
Volume: 24
Issue: 47
Pages: 10750-62
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Publication
21147989 | J:166733
First Author: Mobley AS
Year: 2010
Journal: J Neurosci
Title: Hyperpolarization-activated cyclic nucleotide-gated channels in olfactory sensory neurons regulate axon extension and glomerular formation.
Volume: 30
Issue: 49
Pages: 16498-508
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Publication
27277803 | J:231948
First Author: Knoll AT
Year: 2016
Journal: J Neurosci
Title: Quantitative Trait Loci and a Novel Genetic Candidate for Fear Learning.
Volume: 36
Issue: 23
Pages: 6258-68
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Protein Coding Gene
MGP_CAROLIEiJ_G0018920 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0020965 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0020915 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0020890 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0020915 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0020704 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1096392 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0021351 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0020223 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0020666 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0020789 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0020773 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0020865 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0020801 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0021387 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0019976 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0020281 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0015990 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0019799 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
21366727 | J:176840
First Author: Leão KE
Year: 2011
Journal: Eur J Neurosci
Title: Modulation of dendritic synaptic processing in the lateral superior olive by hyperpolarization-activated currents.
Volume: 33
Issue: 8
Pages: 1462-70
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Publication
19747469 | J:157412
 
First Author: Massella A
Year: 2009
Journal: Brain Res
Title: Gabapentin treatment improves motor coordination in a mice model of progressive ataxia.
Volume: 1301
Pages: 135-42
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Publication
16923751 | J:125245
First Author: Tse HF
Year: 2006
Journal: Circulation
Title: Bioartificial sinus node constructed via in vivo gene transfer of an engineered pacemaker HCN Channel reduces the dependence on electronic pacemaker in a sick-sinus syndrome model.
Volume: 114
Issue: 10
Pages: 1000-11
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