Coronins belongs to the WD40-repeat family, which contains the WD40 motifs that act as the protein-protein interaction sites. There are several isoforms of Coronin in mammalian cells []. This entry represents Coronin 2B (also known as ClipinC). It is predominantly expressed in the brain []. It is a component part of the cross-bridge between the actin cytoskeleton and the plasma membrane. Coronin 2B may play specific roles in the reorganisation of neuronal actin structure [].
