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Search results 1401 to 1471 out of 1471 for Mitf

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Type Details Score
Publication
22465131 | J:183625
First Author: Guo H
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Wnt3a promotes melanin synthesis of mouse hair follicle melanocytes.
Volume: 420
Issue: 4
Pages: 799-804
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Publication
28887433 | J:250821
First Author: Drube S
Year: 2017
Journal: J Immunol
Title: The Neurobeachin-like 2 Protein Regulates Mast Cell Homeostasis.
Volume: 199
Issue: 8
Pages: 2948-2957
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Publication
8645245 | J:31866
First Author: Fuse N
Year: 1996
Journal: Biochem Biophys Res Commun
Title: Identification of a melanocyte-type promoter of the microphthalmia-associated transcription factor gene.
Volume: 219
Issue: 3
Pages: 702-7
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Publication
19201870 | J:144792
First Author: Yagil Z
Year: 2009
Journal: J Immunol
Title: A specific epitope of protein inhibitor of activated STAT3 is responsible for the induction of apoptosis in rat transformed mast cells.
Volume: 182
Issue: 4
Pages: 2168-75
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Publication
30061422 | J:266274
First Author: Yang Y
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Central role of autophagic UVRAG in melanogenesis and the suntan response.
Volume: 115
Issue: 33
Pages: E7728-E7737
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Publication
31000662 | J:273636
First Author: He M
Year: 2019
Journal: Science
Title: Intrinsic apoptosis shapes the tumor spectrum linked to inactivation of the deubiquitinase BAP1.
Volume: 364
Issue: 6437
Pages: 283-285
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Publication
33441552 | J:300898
First Author: Wu CL
Year: 2021
Journal: Nat Commun
Title: Single cell transcriptomic analysis of human pluripotent stem cell chondrogenesis.
Volume: 12
Issue: 1
Pages: 362
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Publication
33479210 | J:301256
First Author: Li Y
Year: 2021
Journal: Nat Commun
Title: GATA2 regulates mast cell identity and responsiveness to antigenic stimulation by promoting chromatin remodeling at super-enhancers.
Volume: 12
Issue: 1
Pages: 494
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Publication
29467326 | J:330939
 
First Author: Palam LR
Year: 2018
Journal: JCI Insight
Title: Loss of epigenetic regulator TET2 and oncogenic KIT regulate myeloid cell transformation via PI3K pathway.
Volume: 3
Issue: 4
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Publication
18508457 | -
 
First Author: Loesch M
Year: 2008
Journal: Front Biosci
Title: The p38 MAPK stress pathway as a tumor suppressor or more?
Volume: 13
Pages: 3581-93
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Publication
28903453 | -
First Author: Corre I
Year: 2017
Journal: Oncotarget
Title: The p38 pathway, a major pleiotropic cascade that transduces stress and metastatic signals in endothelial cells.
Volume: 8
Issue: 33
Pages: 55684-55714
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Publication
17534150 | -
First Author: Perdiguero E
Year: 2007
Journal: Cell Cycle
Title: Genetic deficiency of p38alpha reveals its critical role in myoblast cell cycle exit: the p38alpha-JNK connection.
Volume: 6
Issue: 11
Pages: 1298-303
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Publication
17957136 | -
First Author: Hui L
Year: 2007
Journal: Cell Cycle
Title: p38alpha: a suppressor of cell proliferation and tumorigenesis.
Volume: 6
Issue: 20
Pages: 2429-33
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Protein Domain
IPR038784 | p38alpha
Type: Family
Description: p38 kinases are mitogen-activated protein kinases (MAPKs), serving as important mediators of cellular responses to extracellular signals. They function in the regulation of the cell cycle, cell development, cell differentiation, senescence, tumorigenesis, apoptosis, pain development and pain progression, and immune responses. p38 kinases are activated by the MAPK kinases MKK3 and MKK6, which in turn are activated by upstream MAPK kinase kinases including TAK1, ASK1, and MLK3, in response to cellular stresses or inflammatory cytokines []. p38 substrates include other protein kinases and factors that regulate transcription, nuclear export, mRNA stability and translation. p38 kinases are drug targets for the inflammatory diseases psoriasis, rheumatoid arthritis, and chronic pulmonary disease [, ].Vertebrates contain four p38 kinases, named alpha, beta, gamma, and delta, which show varying substrate specificity and expression patterns.p38alpha/MAPK14 is expressed in most tissues and is the major isoform involved in the immune and inflammatory response. It is the central p38 MAPK involved in myogenesis []. It plays a role in regulating cell cycle check-point transition and promoting cell differentiation. p38alpha also regulates cell proliferation and death through crosstalk with the JNK pathway []. Its substrates include MAPK activated protein kinase 2 (MK2), MK5, and the transcription factors ATF2 and Mitf [].
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Strain
MGI:6792071 | STOCK Braf<tm1Mmcm> Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze> Tg(Mitf-cre)7114Gsb/Cvrk
Attribute String: mutant stock, targeted mutation, transgenic
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Strain
MGI:5702902 | C3FeJ.Cg-Gt(ROSA)26Sor<tm1(GNAQ*)Cvrk>/Gt(ROSA)26Sor<tm1Sor> Tg(Mitf-cre)7114Gsb/Cvrk
Attribute String: congenic, mutant strain, targeted mutation, transgenic
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Strain
MGI:6792057 | C3FeJ.Cg-Gt(ROSA)26Sor<tm1(GNAQ*)Cvrk>/Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze> Tg(Mitf-cre)7114Gsb/Cvrk
Attribute String: congenic, mutant strain, targeted mutation, transgenic
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor Tg(Mitf-cre)7114Gsb/?
Background: C3FeJ.Cg-Gt(ROSA)26Sor/Gt(ROSA)26Sor Tg(Mitf-cre)7114Gsb/Cvrk
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Adamts9/Adamts9 Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Mitf-cre)7114Gsb/?
Background: involves: 129S6/SvEvTac * C3HeB/FeJ * C57BL/6N * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor Tg(Mitf-cre)7114Gsb/?
Background: C3FeJ.Cg-Gt(ROSA)26Sor/Gt(ROSA)26Sor Tg(Mitf-cre)7114Gsb/Cvrk
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Braf/Braf<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Mitf-cre)7114Gsb/?
Background: STOCK Braf Gt(ROSA)26Sor Tg(Mitf-cre)7114Gsb/Cvrk
Zygosity: cn
Has Mutant Allele: true
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Publication
11141502 | J:67337
First Author: Ge Y
Year: 2001
Journal: Am J Pathol
Title: Independent influence of strain difference and mi transcription factor on the expression of mouse mast cell chymases.
Volume: 158
Issue: 1
Pages: 281-92
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Publication
26486273 | J:313949
First Author: Pan L
Year: 2015
Journal: Cell Prolif
Title: Microphthalmia-associated transcription factor/T-box factor-2 axis acts through Cyclin D1 to regulate melanocyte proliferation.
Volume: 48
Issue: 6
Pages: 631-42
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Publication
12668617 | J:82934
First Author: Lang D
Year: 2003
Journal: Hum Mol Genet
Title: Sox10 and Pax3 physically interact to mediate activation of a conserved c-RET enhancer.
Volume: 12
Issue: 8
Pages: 937-45
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Publication
17184764 | J:118797
First Author: Halilagic A
Year: 2007
Journal: Dev Biol
Title: Retinoids control anterior and dorsal properties in the developing forebrain.
Volume: 303
Issue: 1
Pages: 362-75
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Publication
12444107 | J:80529
First Author: Sánchez-Martín M
Year: 2002
Journal: Hum Mol Genet
Title: SLUG (SNAI2) deletions in patients with Waardenburg disease.
Volume: 11
Issue: 25
Pages: 3231-6
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Publication
20501942 | J:161631
First Author: Ito Y
Year: 2010
Journal: J Clin Invest
Title: Cdc42 regulates bone modeling and remodeling in mice by modulating RANKL/M-CSF signaling and osteoclast polarization.
Volume: 120
Issue: 6
Pages: 1981-93
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Publication
33283624 | J:335419
First Author: Assenmacher CA
Year: 2021
Journal: J Histochem Cytochem
Title: Classification and Grading of Melanocytic Lesions in a Mouse Model of NRAS-driven Melanomagenesis.
Volume: 69
Issue: 3
Pages: 203-218
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Publication
35649693 | J:341494
 
First Author: Wang J
Year: 2022
Journal: Life Sci Alliance
Title: VDAC1 negatively regulates melanogenesis through the Ca(2+)-calcineurin-CRTC1-MITF pathway.
Volume: 5
Issue: 10
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Publication
20036645 | J:157090
First Author: Takemura K
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Class A scavenger receptor promotes osteoclast differentiation via the enhanced expression of receptor activator of NF-kappaB (RANK).
Volume: 391
Issue: 4
Pages: 1675-80
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Publication
27078017 | J:252394
First Author: Bhattacharyya S
Year: 2016
Journal: PLoS One
Title: Inhibition of Phosphatase Activity Follows Decline in Sulfatase Activity and Leads to Transcriptional Effects through Sustained Phosphorylation of Transcription Factor MITF.
Volume: 11
Issue: 4
Pages: e0153463
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Publication
24107965 | J:202754
First Author: Kokkinaki M
Year: 2013
Journal: J Neurosci
Title: Klotho regulates retinal pigment epithelial functions and protects against oxidative stress.
Volume: 33
Issue: 41
Pages: 16346-59
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Publication
25256614 | J:217894
First Author: Smith MP
Year: 2014
Journal: Cancer Discov
Title: The immune microenvironment confers resistance to MAPK pathway inhibitors through macrophage-derived TNFα.
Volume: 4
Issue: 10
Pages: 1214-1229
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Publication
14982938 | J:201036
First Author: Esumi N
Year: 2004
Journal: J Biol Chem
Title: Analysis of the VMD2 promoter and implication of E-box binding factors in its regulation.
Volume: 279
Issue: 18
Pages: 19064-73
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Publication
11700328 | J:73642
First Author: Du J
Year: 2002
Journal: J Biol Chem
Title: Identification of Aim-1 as the underwhite mouse mutant and its transcriptional regulation by MITF.
Volume: 277
Issue: 1
Pages: 402-6
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Publication
29062096 | J:255707
First Author: Dong C
Year: 2017
Journal: Sci Rep
Title: Functional Role of Cyclin-Dependent Kinase 5 in the Regulation of Melanogenesis and Epidermal Structure.
Volume: 7
Issue: 1
Pages: 13783
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Publication
9256061 | J:42217
First Author: Yasumoto K
Year: 1997
Journal: Biochim Biophys Acta
Title: Molecular cloning of cDNA encoding a human TFEC isoform, a newly identified transcriptional regulator.
Volume: 1353
Issue: 1
Pages: 23-31
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Publication
10068667 | J:53440
First Author: Jippo T
Year: 1999
Journal: Blood
Title: Deficient transcription of mouse mast cell protease 4 gene in mutant mice of mi/mi genotype.
Volume: 93
Issue: 6
Pages: 1942-50
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Publication
10487831 | J:57499
First Author: King R
Year: 1999
Journal: Am J Pathol
Title: Microphthalmia transcription factor. A sensitive and specific melanocyte marker for MelanomaDiagnosis.
Volume: 155
Issue: 3
Pages: 731-8
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Publication
16197942 | J:104480
First Author: Bordogna W
Year: 2005
Journal: Exp Cell Res
Title: EMX homeobox genes regulate microphthalmia and alter melanocyte biology.
Volume: 311
Issue: 1
Pages: 27-38
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Publication
19214986 | J:146625
First Author: Hachiya A
Year: 2009
Journal: J Pathol
Title: Stem cell factor-KIT signalling plays a pivotal role in regulating pigmentation in mammalian hair.
Volume: 218
Issue: 1
Pages: 30-9
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Publication
20207963 | J:164097
First Author: Liu Y
Year: 2010
Journal: Invest Ophthalmol Vis Sci
Title: Taz-tead1 links cell-cell contact to zeb1 expression, proliferation, and dedifferentiation in retinal pigment epithelial cells.
Volume: 51
Issue: 7
Pages: 3372-8
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Publication
25447045 | J:216961
First Author: Dadras SS
Year: 2015
Journal: Am J Pathol
Title: A novel role for microphthalmia-associated transcription factor-regulated pigment epithelium-derived factor during melanoma progression.
Volume: 185
Issue: 1
Pages: 252-65
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Publication
29022913 | J:278709
First Author: Wang J
Year: 2017
Journal: Cell Death Dis
Title: MBD2 upregulates miR-301a-5p to induce kidney cell apoptosis during vancomycin-induced AKI.
Volume: 8
Issue: 10
Pages: e3120
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Publication
27859996 | J:303452
First Author: Ohba K
Year: 2016
Journal: Genes Cells
Title: Microphthalmia-associated transcription factor ensures the elongation of axons and dendrites in the mouse frontal cortex.
Volume: 21
Issue: 12
Pages: 1365-1379
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Publication
31065107 | J:303002
First Author: Laurette P
Year: 2020
Journal: Cell Death Differ
Title: Chromatin remodellers Brg1 and Bptf are required for normal gene expression and progression of oncogenic Braf-driven mouse melanoma.
Volume: 27
Issue: 1
Pages: 29-43
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Publication
34156976 | J:308506
 
First Author: Panza E
Year: 2021
Journal: J Clin Invest
Title: The clear cell sarcoma functional genomic landscape.
Volume: 131
Issue: 15
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Publication
18641651 | J:139244
First Author: McGowan KA
Year: 2008
Journal: Nat Genet
Title: Ribosomal mutations cause p53-mediated dark skin and pleiotropic effects.
Volume: 40
Issue: 8
Pages: 963-70
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Publication
26113083 | J:225597
First Author: Huang JL
Year: 2015
Journal: Cancer Res
Title: Oncogenic G Protein GNAQ Induces Uveal Melanoma and Intravasation in Mice.
Volume: 75
Issue: 16
Pages: 3384-97
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Protein
Q64092
Organism: Mus musculus/domesticus
Length: 572  
Fragment?: false
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Protein
Q9WTW4
Organism: Mus musculus/domesticus
Length: 317  
Fragment?: false
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Protein
Q9R210
Organism: Mus musculus/domesticus
Length: 475  
Fragment?: false
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Protein
Q3UKG7
Organism: Mus musculus/domesticus
Length: 534  
Fragment?: false
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Protein
A2AEW1
Organism: Mus musculus/domesticus
Length: 572  
Fragment?: false
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Protein
Q3U1L5
Organism: Mus musculus/domesticus
Length: 539  
Fragment?: true
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Protein
A2AEW0
Organism: Mus musculus/domesticus
Length: 537  
Fragment?: false
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Protein
Q6P203
Organism: Mus musculus/domesticus
Length: 534  
Fragment?: false
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Protein
Q3U327
Organism: Mus musculus/domesticus
Length: 475  
Fragment?: false
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Publication
10770922 | J:63660
First Author: Carreira S
Year: 2000
Journal: J Biol Chem
Title: The gene encoding the T-box factor Tbx2 is a target for the microphthalmia-associated transcription factor in melanocytes.
Volume: 275
Issue: 29
Pages: 21920-7
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Publication
29781574 | J:262498
     
First Author: Tharmarajah G
Year: 2018
Journal: Pigment Cell Melanoma Res
Title: Melanocyte development in the mouse tail epidermis requires the Adamts9 metalloproteinase.
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Protein
Q8R010
Organism: Mus musculus/domesticus
Length: 320  
Fragment?: false
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Publication
23954936 | -
First Author: Arthur JS
Year: 2013
Journal: Nat Rev Immunol
Title: Mitogen-activated protein kinases in innate immunity.
Volume: 13
Issue: 9
Pages: 679-92
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Protein
Q8C5F1
Organism: Mus musculus/domesticus
Length: 306  
Fragment?: false
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Protein
F6W7D6
Organism: Mus musculus/domesticus
Length: 334  
Fragment?: true
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Protein
D3Z6Q7
Organism: Mus musculus/domesticus
Length: 267  
Fragment?: false
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Publication
34939927 | J:318008
   
First Author: Urtatiz O
Year: 2021
Journal: Elife
Title: Crosstalk with keratinocytes causes GNAQ oncogene specificity in melanoma.
Volume: 10
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Publication
- | J:312561
     
First Author: Urtatiz1 O
Year: 2021
Journal: bioRxiv
Title: Crosstalk with keratinocytes causes GNAQ oncogene specificity in melanoma.
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Publication
22810304 | J:196495
First Author: Deo M
Year: 2013
Journal: J Invest Dermatol
Title: Differential effects of neurofibromin gene dosage on melanocyte development.
Volume: 133
Issue: 1
Pages: 49-58
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Protein
P47811
Organism: Mus musculus/domesticus
Length: 360  
Fragment?: false
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Protein
Q5U421
Organism: Mus musculus/domesticus
Length: 360  
Fragment?: false
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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