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Search results 101 to 200 out of 732 for Nr1h4

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Type Details Score
Publication
24291500 | J:211881
First Author: Peng X
Year: 2014
Journal: Biochem Biophys Res Commun
Title: Activation of farnesoid X receptor induces RECK expression in mouse liver.
Volume: 443
Issue: 1
Pages: 211-6
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23178280 | J:193337
First Author: Zhu Y
Year: 2013
Journal: Toxicol Appl Pharmacol
Title: Modulation of farnesoid X receptor results in post-translational modification of poly (ADP-ribose) polymerase 1 in the liver.
Volume: 266
Issue: 2
Pages: 260-6
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Publication
14729567 | J:87780
First Author: Zhang Y
Year: 2004
Journal: Genes Dev
Title: Peroxisome proliferator-activated receptor-gamma coactivator 1alpha (PGC-1alpha) regulates triglyceride metabolism by activation of the nuclear receptor FXR.
Volume: 18
Issue: 2
Pages: 157-69
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Publication
23372731 | J:195920
First Author: Renga B
Year: 2013
Journal: PLoS One
Title: The bile acid sensor FXR is required for immune-regulatory activities of TLR-9 in intestinal inflammation.
Volume: 8
Issue: 1
Pages: e54472
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Publication
30354208 | J:285164
First Author: Singh AB
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: Farnesoid X Receptor Activation by Obeticholic Acid Elevates Liver Low-Density Lipoprotein Receptor Expression by mRNA Stabilization and Reduces Plasma Low-Density Lipoprotein Cholesterol in Mice.
Volume: 38
Issue: 10
Pages: 2448-2459
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Publication
22952826 | J:191657
First Author: Williams JA
Year: 2012
Journal: PLoS One
Title: Tissue specific induction of p62/Sqstm1 by farnesoid X receptor.
Volume: 7
Issue: 8
Pages: e43961
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Publication
28380377 | J:251866
First Author: Hao H
Year: 2017
Journal: Cell Metab
Title: Farnesoid X Receptor Regulation of the NLRP3 Inflammasome Underlies Cholestasis-Associated Sepsis.
Volume: 25
Issue: 4
Pages: 856-867.e5
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Publication
18448072 | J:136213
First Author: Inoue J
Year: 2008
Journal: Biochem Biophys Res Commun
Title: PPARalpha gene expression is up-regulated by LXR and PXR activators in the small intestine.
Volume: 371
Issue: 4
Pages: 675-8
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Publication
24091600 | J:210561
First Author: Li G
Year: 2013
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Mechanisms of STAT3 activation in the liver of FXR knockout mice.
Volume: 305
Issue: 11
Pages: G829-37
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Publication
21296199 | J:182376
First Author: Renga B
Year: 2011
Journal: Biochim Biophys Acta
Title: Farnesoid X receptor suppresses constitutive androstane receptor activity at the multidrug resistance protein-4 promoter.
Volume: 1809
Issue: 3
Pages: 157-65
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Publication
16423920 | J:111085
First Author: Boyer JL
Year: 2006
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Upregulation of a basolateral FXR-dependent bile acid efflux transporter OSTalpha-OSTbeta in cholestasis in humans and rodents.
Volume: 290
Issue: 6
Pages: G1124-30
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Publication
16251721 | J:106031
First Author: Lee H
Year: 2006
Journal: J Lipid Res
Title: FXR regulates organic solute transporters alpha and beta in the adrenal gland, kidney, and intestine.
Volume: 47
Issue: 1
Pages: 201-14
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Publication
22447981 | J:187477
First Author: Renga B
Year: 2012
Journal: FASEB J
Title: Glucocorticoid receptor mediates the gluconeogenic activity of the farnesoid X receptor in the fasting condition.
Volume: 26
Issue: 7
Pages: 3021-31
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Publication
25383523 | J:217540
First Author: Seok S
Year: 2014
Journal: Nature
Title: Transcriptional regulation of autophagy by an FXR-CREB axis.
Volume: 516
Issue: 7529
Pages: 108-11
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Publication
16357057 | J:111080
First Author: Zollner G
Year: 2006
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Coordinated induction of bile acid detoxification and alternative elimination in mice: role of FXR-regulated organic solute transporter-alpha/beta in the adaptive response to bile acids.
Volume: 290
Issue: 5
Pages: G923-32
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Publication
36508655 | J:336725
First Author: Fu T
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: FXR mediates ILC-intrinsic responses to intestinal inflammation.
Volume: 119
Issue: 51
Pages: e2213041119
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Publication
14592843 | J:86340
First Author: Korstanje R
Year: 2004
Journal: Arterioscler Thromb Vasc Biol
Title: Quantitative trait locus mapping of genes that regulate phospholipid transfer activity in SM/J and NZB/BlNJ inbred mice.
Volume: 24
Issue: 1
Pages: 155-60
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Publication
30208322 | J:271254
First Author: Han CY
Year: 2018
Journal: Cell Rep
Title: FXR Inhibits Endoplasmic Reticulum Stress-Induced NLRP3 Inflammasome in Hepatocytes and Ameliorates Liver Injury.
Volume: 24
Issue: 11
Pages: 2985-2999
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16557297 | J:107809
First Author: Ma K
Year: 2006
Journal: J Clin Invest
Title: Farnesoid X receptor is essential for normal glucose homeostasis.
Volume: 116
Issue: 4
Pages: 1102-9
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Publication
16473946 | J:107133
First Author: Inagaki T
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor.
Volume: 103
Issue: 10
Pages: 3920-5
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Publication
22057115 | J:319839
First Author: Modica S
Year: 2012
Journal: Gastroenterology
Title: Selective activation of nuclear bile acid receptor FXR in the intestine protects mice against cholestasis.
Volume: 142
Issue: 2
Pages: 355-65.e1-4
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Publication
25651182 | J:219776
First Author: de Aguiar Vallim TQ
Year: 2015
Journal: Cell Metab
Title: MAFG is a transcriptional repressor of bile acid synthesis and metabolism.
Volume: 21
Issue: 2
Pages: 298-310
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28478385 | J:245978
First Author: Pathak P
Year: 2017
Journal: J Biol Chem
Title: Farnesoid X receptor induces Takeda G-protein receptor 5 cross-talk to regulate bile acid synthesis and hepatic metabolism.
Volume: 292
Issue: 26
Pages: 11055-11069
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Publication
24656817 | J:211826
First Author: Degirolamo C
Year: 2014
Journal: Cell Rep
Title: Microbiota modification with probiotics induces hepatic bile acid synthesis via downregulation of the Fxr-Fgf15 axis in mice.
Volume: 7
Issue: 1
Pages: 12-8
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Publication
27170759 | J:234475
First Author: Schupp AK
Year: 2016
Journal: J Virol
Title: Bile Acids Act as Soluble Host Restriction Factors Limiting Cytomegalovirus Replication in Hepatocytes.
Volume: 90
Issue: 15
Pages: 6686-98
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Publication
38258906 | J:345589
 
First Author: Dong X
Year: 2024
Journal: JCI Insight
Title: Farnesoid X receptor mediates macrophage-intrinsic responses to suppress colitis-induced colon cancer progression.
Volume: 9
Issue: 2
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Publication
28894223 | J:255559
First Author: Cariello M
Year: 2017
Journal: Sci Rep
Title: Long-term Administration of Nuclear Bile Acid Receptor FXR Agonist Prevents Spontaneous Hepatocarcinogenesis in Abcb4-/- Mice.
Volume: 7
Issue: 1
Pages: 11203
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Publication
23519696 | J:213311
First Author: de Aguiar Vallim TQ
Year: 2013
Journal: Circ Res
Title: MicroRNA-144 regulates hepatic ATP binding cassette transporter A1 and plasma high-density lipoprotein after activation of the nuclear receptor farnesoid X receptor.
Volume: 112
Issue: 12
Pages: 1602-12
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Publication
28586124 | J:273942
First Author: Akinrotimi O
Year: 2017
Journal: Hepatology
Title: Small heterodimer partner deletion prevents hepatic steatosis and when combined with farnesoid X receptor loss protects against type 2 diabetes in mice.
Volume: 66
Issue: 6
Pages: 1854-1865
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Publication
19965601 | J:160197
First Author: Liu B
Year: 2010
Journal: J Lipid Res
Title: Cyclodextrin overcomes the transport defect in nearly every organ of NPC1 mice leading to excretion of sequestered cholesterol as bile acid.
Volume: 51
Issue: 5
Pages: 933-44
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Publication
29142166 | J:273929
First Author: Miyata M
Year: 2017
Journal: J Toxicol Sci
Title: Fish oil feeding reverses hepatomegaly and disrupted hepatic function due to the lack of FXR signaling.
Volume: 42
Issue: 6
Pages: 671-681
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12891557 | J:228417
First Author: Claudel T
Year: 2003
Journal: Gastroenterology
Title: Farnesoid X receptor agonists suppress hepatic apolipoprotein CIII expression.
Volume: 125
Issue: 2
Pages: 544-55
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16446356 | J:110560
First Author: Cariou B
Year: 2006
Journal: J Biol Chem
Title: The farnesoid X receptor modulates adiposity and peripheral insulin sensitivity in mice.
Volume: 281
Issue: 16
Pages: 11039-49
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16410358 | J:105654
First Author: Zhang Y
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice.
Volume: 103
Issue: 4
Pages: 1006-11
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Publication
19047134 | J:142094
First Author: Modica S
Year: 2008
Journal: Cancer Res
Title: Nuclear bile acid receptor FXR protects against intestinal tumorigenesis.
Volume: 68
Issue: 23
Pages: 9589-94
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Publication
20447400 | J:161322
First Author: Popescu IR
Year: 2010
Journal: FEBS Lett
Title: The nuclear receptor FXR is expressed in pancreatic beta-cells and protects human islets from lipotoxicity.
Volume: 584
Issue: 13
Pages: 2845-51
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Publication
30122655 | J:272709
First Author: Jain U
Year: 2018
Journal: Cell Host Microbe
Title: Temporal Regulation of the Bacterial Metabolite Deoxycholate during Colonic Repair Is Critical for Crypt Regeneration.
Volume: 24
Issue: 3
Pages: 353-363.e5
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27956139 | J:255615
First Author: Bijsmans IT
Year: 2017
Journal: Biochim Biophys Acta
Title: Characterization of stem cell-derived liver and intestinal organoids as a model system to study nuclear receptor biology.
Volume: 1863
Issue: 3
Pages: 687-700
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Publication
22474125 | J:317843
First Author: Prade E
Year: 2012
Journal: Mol Endocrinol
Title: Bile acids down-regulate caveolin-1 in esophageal epithelial cells through sterol responsive element-binding protein.
Volume: 26
Issue: 5
Pages: 819-32
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Publication
33895309 | J:320453
First Author: Zaufel A
Year: 2021
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Secondary (iso)BAs cooperate with endogenous ligands to activate FXR under physiological and pathological conditions.
Volume: 1867
Issue: 8
Pages: 166153
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Publication
16825595 | J:128055
First Author: Zhang Y
Year: 2006
Journal: Arterioscler Thromb Vasc Biol
Title: FXR deficiency causes reduced atherosclerosis in Ldlr-/- mice.
Volume: 26
Issue: 10
Pages: 2316-21
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Publication
20851881 | J:167021
First Author: Abdelkarim M
Year: 2010
Journal: J Biol Chem
Title: The farnesoid X receptor regulates adipocyte differentiation and function by promoting peroxisome proliferator-activated receptor-gamma and interfering with the Wnt/beta-catenin pathways.
Volume: 285
Issue: 47
Pages: 36759-67
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Publication
21123943 | J:171856
First Author: Anakk S
Year: 2011
Journal: J Clin Invest
Title: Combined deletion of Fxr and Shp in mice induces Cyp17a1 and results in juvenile onset cholestasis.
Volume: 121
Issue: 1
Pages: 86-95
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Publication
16844773 | J:111798
First Author: Stedman C
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Benefit of farnesoid X receptor inhibition in obstructive cholestasis.
Volume: 103
Issue: 30
Pages: 11323-8
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Publication
19028791 | J:146332
First Author: Mencarelli A
Year: 2009
Journal: Am J Physiol Heart Circ Physiol
Title: Antiatherosclerotic effect of farnesoid X receptor.
Volume: 296
Issue: 2
Pages: H272-81
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Publication
17110163 | J:118172
First Author: Guo GL
Year: 2006
Journal: Biochim Biophys Acta
Title: Effects of FXR in foam-cell formation and atherosclerosis development.
Volume: 1761
Issue: 12
Pages: 1401-9
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16186601 | J:106149
First Author: Hanniman EA
Year: 2005
Journal: J Lipid Res
Title: Loss of functional farnesoid X receptor increases atherosclerotic lesions in apolipoprotein E-deficient mice.
Volume: 46
Issue: 12
Pages: 2595-604
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Publication
32034442 | J:288188
First Author: Qiu Y
Year: 2020
Journal: Diabetologia
Title: The glucose-lowering effects of α-glucosidase inhibitor require a bile acid signal in mice.
Volume: 63
Issue: 5
Pages: 1002-1016
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Publication
37123234 | J:335732
First Author: Xiang M
Year: 2023
Journal: iScience
Title: Aquaporin-8 ameliorates hepatic steatosis through farnesoid X receptor in obese mice.
Volume: 26
Issue: 4
Pages: 106561
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Publication
30862680 | J:275483
First Author: DePaoli AM
Year: 2019
Journal: Diabetes
Title: FGF19 Analog as a Surgical Factor Mimetic That Contributes to Metabolic Effects Beyond Glucose Homeostasis.
Volume: 68
Issue: 6
Pages: 1315-1328
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11030617 | J:64792
First Author: Sinal CJ
Year: 2000
Journal: Cell
Title: Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.
Volume: 102
Issue: 6
Pages: 731-44
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21804189 | J:178263
First Author: Chennamsetty I
Year: 2011
Journal: J Clin Invest
Title: Farnesoid X receptor represses hepatic human APOA gene expression.
Volume: 121
Issue: 9
Pages: 3724-34
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31862954 | J:287110
First Author: Saeed A
Year: 2019
Journal: Sci Rep
Title: Farnesoid X receptor and bile acids regulate vitamin A storage.
Volume: 9
Issue: 1
Pages: 19493
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Publication
35216094 | J:321595
 
First Author: Kim EY
Year: 2022
Journal: Int J Mol Sci
Title: Transcriptional Control of Trpm6 by the Nuclear Receptor FXR.
Volume: 23
Issue: 4
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32914211 | J:309788
First Author: Alam G
Year: 2020
Journal: Pflugers Arch
Title: Activation of farnesoid X receptor (FXR) induces crystallin zeta expression in mouse medullary collecting duct cells.
Volume: 472
Issue: 11
Pages: 1631-1641
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29739889 | J:262495
First Author: Xu S
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Farnesoid X receptor is essential for the survival of renal medullary collecting duct cells under hypertonic stress.
Volume: 115
Issue: 21
Pages: 5600-5605
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Publication
24365583 | J:323205
First Author: Chow EC
Year: 2014
Journal: Gastroenterology
Title: Vitamin D receptor activation down-regulates the small heterodimer partner and increases CYP7A1 to lower cholesterol.
Volume: 146
Issue: 4
Pages: 1048-59
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Publication
25496033 | J:223255
First Author: Wang YD
Year: 2015
Journal: Mol Endocrinol
Title: Farnesoid X receptor antagonizes JNK signaling pathway in liver carcinogenesis by activating SOD3.
Volume: 29
Issue: 2
Pages: 322-31
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Publication
21224055 | J:168234
First Author: Allen K
Year: 2011
Journal: Am J Pathol
Title: Bile acids induce inflammatory genes in hepatocytes: a novel mechanism of inflammation during obstructive cholestasis.
Volume: 178
Issue: 1
Pages: 175-86
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19996107 | J:159763
First Author: Zhang Y
Year: 2010
Journal: J Biol Chem
Title: Identification of novel pathways that control farnesoid X receptor-mediated hypocholesterolemia.
Volume: 285
Issue: 5
Pages: 3035-43
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20850540 | J:170790
First Author: Iakova P
Year: 2011
Journal: Semin Cancer Biol
Title: Intracellular signaling and hepatocellular carcinoma.
Volume: 21
Issue: 1
Pages: 28-34
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19407337 | J:149881
First Author: Cui YJ
Year: 2009
Journal: Toxicol Sci
Title: Compensatory induction of liver efflux transporters in response to ANIT-induced liver injury is impaired in FXR-null mice.
Volume: 110
Issue: 1
Pages: 47-60
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Publication
25500885 | J:219603
First Author: Jiang C
Year: 2015
Journal: J Clin Invest
Title: Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease.
Volume: 125
Issue: 1
Pages: 386-402
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Publication
17720959 | J:129978
First Author: Kim I
Year: 2007
Journal: J Lipid Res
Title: Differential regulation of bile acid homeostasis by the farnesoid X receptor in liver and intestine.
Volume: 48
Issue: 12
Pages: 2664-72
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Publication
29976576 | J:264621
First Author: Miyazaki-Anzai S
Year: 2018
Journal: J Lipid Res
Title: Simultaneous inhibition of FXR and TGR5 exacerbates atherosclerotic formation.
Volume: 59
Issue: 9
Pages: 1709-1713
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Publication
28891815 | J:247719
First Author: Tarling EJ
Year: 2017
Journal: J Clin Invest
Title: RNA-binding protein ZFP36L1 maintains posttranscriptional regulation of bile acid metabolism.
Volume: 127
Issue: 10
Pages: 3741-3754
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16609145 | J:112052
First Author: Ratliff EP
Year: 2006
Journal: J Lipid Res
Title: Transgenic expression of CYP7A1 in LDL receptor-deficient mice blocks diet-induced hypercholesterolemia.
Volume: 47
Issue: 7
Pages: 1513-20
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Publication
21593203 | J:186756
First Author: Prawitt J
Year: 2011
Journal: Diabetes
Title: Farnesoid X receptor deficiency improves glucose homeostasis in mouse models of obesity.
Volume: 60
Issue: 7
Pages: 1861-71
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12923173 | J:129256
First Author: Guo GL
Year: 2003
Journal: J Biol Chem
Title: Complementary roles of farnesoid X receptor, pregnane X receptor, and constitutive androstane receptor in protection against bile acid toxicity.
Volume: 278
Issue: 46
Pages: 45062-71
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17289919 | J:118368
First Author: Volle DH
Year: 2007
Journal: Genes Dev
Title: The small heterodimer partner is a gonadal gatekeeper of sexual maturation in male mice.
Volume: 21
Issue: 3
Pages: 303-15
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16614213 | J:108344
First Author: Huang W
Year: 2006
Journal: Science
Title: Nuclear receptor-dependent bile acid signaling is required for normal liver regeneration.
Volume: 312
Issue: 5771
Pages: 233-6
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29718219 | J:262945
First Author: Kim KH
Year: 2018
Journal: Endocrinology
Title: Xenobiotic Nuclear Receptor Signaling Determines Molecular Pathogenesis of Progressive Familial Intrahepatic Cholestasis.
Volume: 159
Issue: 6
Pages: 2435-2446
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23172628 | J:317849
First Author: Jiang Y
Year: 2013
Journal: Hepatology
Title: Farnesoid X receptor inhibits gankyrin in mouse livers and prevents development of liver cancer.
Volume: 57
Issue: 3
Pages: 1098-106
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Publication
22542490 | J:320452
First Author: Lan T
Year: 2012
Journal: J Hepatol
Title: Mouse organic solute transporter alpha deficiency alters FGF15 expression and bile acid metabolism.
Volume: 57
Issue: 2
Pages: 359-65
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22261820 | J:316227
First Author: Zhang Y
Year: 2012
Journal: Mol Endocrinol
Title: Loss of FXR protects against diet-induced obesity and accelerates liver carcinogenesis in ob/ob mice.
Volume: 26
Issue: 2
Pages: 272-80
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16284190 | J:118817
First Author: Gutierrez A
Year: 2006
Journal: Arterioscler Thromb Vasc Biol
Title: Bile acids decrease hepatic paraoxonase 1 expression and plasma high-density lipoprotein levels via FXR-mediated signaling of FGFR4.
Volume: 26
Issue: 2
Pages: 301-6
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Publication
27358174 | J:249807
First Author: Arab JP
Year: 2017
Journal: Hepatology
Title: Bile acids and nonalcoholic fatty liver disease: Molecular insights and therapeutic perspectives.
Volume: 65
Issue: 1
Pages: 350-362
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19056864 | J:144235
First Author: Zhang L
Year: 2009
Journal: Mol Endocrinol
Title: Significance and mechanism of CYP7a1 gene regulation during the acute phase of liver regeneration.
Volume: 23
Issue: 2
Pages: 137-45
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23549084 | J:197607
First Author: Seyer P
Year: 2013
Journal: J Clin Invest
Title: Hepatic glucose sensing is required to preserve β cell glucose competence.
Volume: 123
Issue: 4
Pages: 1662-76
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30464200 | J:269976
First Author: Gadaleta RM
Year: 2018
Journal: Sci Rep
Title: Suppression of Hepatic Bile Acid Synthesis by a non-tumorigenic FGF19 analogue Protects Mice from Fibrosis and Hepatocarcinogenesis.
Volume: 8
Issue: 1
Pages: 17210
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21690373 | J:174303
First Author: Sekiya S
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Glycogen synthase kinase 3 β-dependent Snail degradation directs hepatocyte proliferation in normal liver regeneration.
Volume: 108
Issue: 27
Pages: 11175-80
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22144677 | J:180806
First Author: Li T
Year: 2012
Journal: J Biol Chem
Title: Glucose and insulin induction of bile acid synthesis: mechanisms and implication in diabetes and obesity.
Volume: 287
Issue: 3
Pages: 1861-73
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34505013 | J:313519
First Author: Liu S
Year: 2021
Journal: iScience
Title: Metabolic nuclear receptors coordinate energy metabolism to regulate Sox9+ hepatocyte fate.
Volume: 24
Issue: 9
Pages: 103003
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28446510 | J:243442
First Author: Byun S
Year: 2017
Journal: EMBO J
Title: A postprandial FGF19-SHP-LSD1 regulatory axis mediates epigenetic repression of hepatic autophagy.
Volume: 36
Issue: 12
Pages: 1755-1769
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