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Search results 701 to 732 out of 732 for Nr1h4

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Type Details Score
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Allele
Name: nuclear receptor subfamily 1, group H, member 4; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Allele
Name: nuclear receptor subfamily 1, group H, member 4; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
Publication  
First Author: Modica S
Year: 2010
Journal: Nucl Recept Signal
Title: Deciphering the nuclear bile acid receptor FXR paradigm.
Volume: 8
Pages: e005
Publication
First Author: Hollman DA
Year: 2012
Journal: Biochim Biophys Acta
Title: Anti-inflammatory and metabolic actions of FXR: insights into molecular mechanisms.
Volume: 1821
Issue: 11
Pages: 1443-52
Publication  
First Author: Bijsmans IT
Year: 2015
Journal: Sci Rep
Title: The glucocorticoid mometasone furoate is a novel FXR ligand that decreases inflammatory but not metabolic gene expression.
Volume: 5
Pages: 14086
Protein Domain
Type: Domain
Description: This entry represents the ligand binding domain found in bile acid receptor NR1H4 (also known as farnesoid X-activated receptor, FXR). NR1H4 is a ligand-activated transcription factor belonging to the nuclear receptor (NR) superfamily. It regulates bile salt, glucose and cholesterol homeostasis by binding to DNA response elements, thereby activating gene expression []. It is a receptor for bile acids (BAs) such as chenodeoxycholic acid (CDCA), lithocholic acid, deoxycholic acid (DCA) and allocholic acid (ACA) []. It also inhibits the immune response via tethering to NF-kappaB [].
Allele
Name: nuclear receptor subfamily 1, group H, member 4; targeted mutation 1, Frank Gonzalez
Allele Type: Targeted
Attribute String: Null/knockout
Publication
First Author: Aboudehen K
Year: 2017
Journal: J Am Soc Nephrol
Title: Hepatocyte Nuclear Factor-1β Regulates Urinary Concentration and Response to Hypertonicity.
Volume: 28
Issue: 10
Pages: 2887-2900
Publication
First Author: Leclerc D
Year: 2013
Journal: Cancer Prev Res (Phila)
Title: Genes with aberrant expression in murine preneoplastic intestine show epigenetic and expression changes in normal mucosa of colon cancer patients.
Volume: 6
Issue: 11
Pages: 1171-81
Strain
Attribute String: targeted mutation, mutant stock
Strain
Attribute String: targeted mutation, mutant strain, congenic
Strain
Attribute String: targeted mutation, congenic
Genotype
Symbol: Nr1h4/Nr1h4
Background: involves: 129X1/SvJ * C57BL/6N
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Nr1h4/Nr1h4
Background: involves: 129
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Nr1h4/Nr1h4
Background: involves: 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Nr1h4/Nr1h4
Background: STOCK Nr1h4/J
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Nr1h4/Nr1h4
Background: involves: 129X1/SvJ * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Nr1h4/Nr1h4
Background: B6.129(FVB)-Nr1h4
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Nr1h4/Nr1h4 Xbp1/Xbp1
Background: involves: 129 * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
Publication
First Author: Trenteseaux C
Year: 2017
Journal: Arterioscler Thromb Vasc Biol
Title: Perinatal Hypercholesterolemia Exacerbates Atherosclerosis Lesions in Offspring by Altering Metabolism of Trimethylamine-N-Oxide and Bile Acids.
Volume: 37
Issue: 11
Pages: 2053-2063
Strain
Attribute String: congenic, mutant strain, targeted mutation
Genotype
Symbol: Nr0b2/Nr0b2 Nr1h4/Nr1h4
Background: B6.129(FVB)-Nr0b2 Nr1h4
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Nr1h4/Nr1h4 Speer6-ps1/Speer6-ps1<+> Xbp1/Xbp1
Background: involves: 129 * C57BL/6J * DBA
Zygosity: cn
Has Mutant Allele: true
Protein
Organism: Mus musculus/domesticus
Length: 488  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 497  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 484  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 497  
Fragment?: false