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Search results 1 to 19 out of 19 for Cbl

Category restricted to InteractionExperiment (x)

0.019s

Categories

Category: InteractionExperiment
Type Details Score
Interaction Experiment
Description: ErbB2 and ErbB4 Cbl binding sites can functionally replace the ErbB1 Cbl binding site.
Interaction Experiment
Description: Cbl and Akt regulate CXCL8-induced and CXCR1- and CXCR2-mediated chemotaxis.
Interaction Experiment
Description: E3 ligase-defective Cbl mutants lead to a generalized mastocytosis and myeloproliferative disease.
Interaction Experiment
Description: Intersectin 1 enhances Cbl ubiquitylation of epidermal growth factor receptor through regulation of Sprouty2-Cbl interaction.
Interaction Experiment
Description: Negative regulation of Rap1 activation by the Cbl E3 ubiquitin ligase.
Interaction Experiment
Description: Hck enhances the adherence of lipopolysaccharide-stimulated macrophages via Cbl and phosphatidylinositol 3-kinase.
Interaction Experiment
Description: Fyn associates with Cbl and phosphorylates tyrosine 731 in Cbl, a binding site for phosphatidylinositol 3-kinase.
Interaction Experiment
Description: Dynamin forms a Src kinase-sensitive complex with Cbl and regulates podosomes and osteoclast activity.
Interaction Experiment
Description: Abl family kinases and Cbl cooperate with the Nck adaptor to modulate Xenopus development.
Interaction Experiment
Description: Association between phosphatidylinositol-3 kinase, Cbl and other tyrosine phosphorylated proteins in colony-stimulating factor-1-stimulated macrophages.
Interaction Experiment
Description: Cbl-mediated negative regulation of platelet-derived growth factor receptor-dependent cell proliferation. A critical role for Cbl tyrosine kinase-binding domain.
Interaction Experiment
Description: A positive regulatory role for Cbl family proteins in tumor necrosis factor-related activation-induced cytokine (trance) and CD40L-mediated Akt activation.
Interaction Experiment
Description: A beta 1 integrin signaling pathway involving Src-family kinases, Cbl and PI-3 kinase is required for macrophage spreading and migration.
Interaction Experiment
Description: Berberine Inhibits Proliferation and Down-Regulates Epidermal Growth Factor Receptor through Activation of Cbl in Colon Tumor Cells.
Interaction Experiment
Description: Phagocytosis in macrophages lacking Cbl reveals an unsuspected role for Fc gamma receptor signaling and actin assembly in target binding.
Interaction Experiment
Description: Binding of Cbl to a phospholipase Cgamma1-docking site on platelet-derived growth factor receptor beta provides a dual mechanism of negative regulation.
Interaction Experiment
Description: Physical and functional association of the cbl protooncogen product with an src-family protein tyrosine kinase, p53/56lyn, in the B cell antigen receptor-mediated signaling.
Interaction Experiment
Description: B cell receptor-mediated antigen gathering requires ubiquitin ligase Cbl and adaptors Grb2 and Dok-3 to recruit dynein to the signaling microcluster.
Interaction Experiment
Description: Requirements for pYXXM motifs in Cbl for binding to the p85 subunit of phosphatidylinositol 3-kinase and Crk, and activation of atypical protein kinase C and glucose transport during insulin action in 3T3/L1 adipocytes.